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Vol. 90. Issue 1.
Pages 85-91 (January - February 2014)
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Vol. 90. Issue 1.
Pages 85-91 (January - February 2014)
ARTIGO ORIGINAL
Open Access
First report on simplified diagnostic criteria for pre-hypertension and hypertension in a national sample of adolescents from the Middle East and North Africa: the CASPIAN-III study
Primeiro relatório sobre critérios de diagnóstico simplificado para pré-hipertensão e hipertensão em uma amostra nacional de adolescentes do Oriente Médio e da África do Norte: o estudo CASPIAN-III
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Roya Kelishadia, Ramin Heshmatb, Gelayol Ardalanc, Mostafa Qorbanid,e, Mahnaz Taslimif, Parinaz Poursafag, Kasra Keramatianh, Majzoubeh Taheric, Mohammad-Esmaeil Motlaghh,
Corresponding author
mohammad-motlagh1389@yahoo.com

Corresponding author.
a Departamento de Pediatria, Centro de Pesquisa de Crescimento e Desenvolvimento Infantil, Isfahan University of Medical Sciences, Isfahan, Irã
b Centro de Pesquisa de Doenças Crônicas, Instituto de Ciências para Endocrinologia e Metabolismo da População, Instituto de Pesquisa em Endocrinologia e Metabolismo, Tehran University of Medical Sciences, Teerã, Irã
c Secretaria de Saúde da População, Família e Escola, Ministério da Saúde e Educação Médica, Teerã, Irã
d Departamento de Saúde Pública, Alborz University of Medical Sciences, Karaj, Irã
e Departamento de Epidemiologia, Iran University of Medical Sciences, Teerã, Irã
f Departamento de Saúde da Escola, Secretaria de Saúde e Forma Física, Ministério da Educação, Teerã, Irã
g Departamento de Meio Ambiente, Centro de Pesquisa Ambiental, Isfahan University of Medical Sciences, Isfahan, Irã
h Departamento de Pediatria, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Irã
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Article information
Abstract
Objective

This study aimed to simplify the diagnostic criteria of pre-hypertension (pre- HTN) and hypertension (HTN) in the pediatric age group, and to determine the accuracy of these simple indexes in a nationally-representative sample of Iranian children and adolescents.

Method

The diagnostic accuracy of the indexes of systolic blood pressure-to-height ratio (SBPHR) and diastolic BPHR (DBPHR) to define pre-HTN and HTN was determined by the area under the curve of the receiver operator characteristic curves.

Results

The study population consisted of 5,738 Iranian students (2,875 females) with mean (SD) age of 14.7 (2.4) years. The prevalences of pre-HTN and HTN were 6.9% and 5.6%. The optimal thresholds for defining pre-HTN were 0.73 in males and 0.71 in females for SBPHR, and 0.47 in males and 0.45 in females for DBPHR, respectively.

The corresponding figures for HTNwere 0.73, 0.71, 0.48, and 0.46, respectively. In both genders, the accuracies of SBPHR and DBPHR in diagnosing pre-HTN and HTN were approximately 80%.

Conclusions

BPHR is a valid, simple, inexpensive, and accurate tool to diagnose pre-HTN and HTN in adolescents. The optimal thresholds of SBPHR and DBPHR were consistent with the corresponding figures in other populations of children and adolescents with different racial and ethnic backgrounds. Thus, it is suggested that the use of these indexes can be generalized in programs aiming to screen elevated blood pressure in the pediatric age group.

Keywords:
Blood pressure
Screening
Pre-hypertension
Hypertension
Adolescence
Resumo
Objetivo

Este estudo visa simplificar os critérios de diagnóstico da pré-hipertensão (pré-HTA) e hipertensão (HTA) na faixa etária pediátrica e determinar a precisão desses índices simple sem uma amostra nacionalmente representativa de crianças e adolescen- tes iranianos.

Método

A precisão diagnóstica dos índices de relação pressão arterial sistólica/altura (RPASA) e RPAA diastólica (RPADA) para definir a pré-HTA e HTA foi determinada pela área sob as curvas de características de operação do receptor.

Resultados

A população estudada contou com 5738 alunos iranianos (2875 meninas) com idade média (DP) de 14,7 (2,4) anos. A prevalência de pré-HTA e HTA foi 6,9% e 5,6%. Os limites ideais para a definição de pré-HTA foram 0,73 em meninos e 0,71 em meninas com relação à RPASA e 0,47 em meninos e 0,45 em meninas com relação à RPADA, res- pectivamente. Os valores correspondentes com relação à HTA foram 0,73, 0,71, 0,48 e 0,46, respectivamente. Em ambos os gêneros, a precisão de RPASA e RPADA no diagnós- tico de pré-HTA e HTA foi de aproximadamente 80%.

Conclusões

A RPAA é uma ferramenta válida, simples, barata e precisa no diagnóstico da pré-HTA e HTA em adolescentes. Os limites ideais de RPASA e RPADA foram compatíveis comos números correspondentes em outra população de crianças e adolescentes com diferentes históricos raciais e étnicos, assim, sugerimos que a utilização desses índices possa ser generalizada em programas de triagem com relação à PA elevada na faixa etária pediátrica.

Palavras-chave:
Pressão sanguínea
Triagem
Pré-hipertensão
Hipertensão
Adolescência
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Como citar este artigo: Kelishadi R, Heshmat R, Ardalan G, Qorbani M, Taslimi M, Poursafa P, et al. First report on simplified diagnostic criteria for pre-hypertension and hypertension in a national sample of adolescents from the Middle East and North Africa: the CASPIAN-III study. J Pediatr (Rio J). 2014;90:85-91.

Copyright © 2013. Brasileira de Pediatria
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