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    "titulo" => "TyG in insulin resistance prediction"
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        "autoresLista" => "Wendell Arthur Lopes, Gustavo Henrique de Oliveira, Jo&#227;o Carlos Locateli, Caroline Ferraz Sim&#245;es"
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          2 => array:2 [
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        "titulo" => "TyG na predi&#231;&#227;o da resist&#234;ncia &#224; insulina"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with interest the article &#8220;The TyG index cutoff point and its association with body adiposity and lifestyle in children&#8221; by Vieira-Ribeiro et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> published in the <span class="elsevierStyleItalic">Jornal de Pediatria&#44;</span> which proposes TyG &#40;triglyceride-glucose &#237;ndex&#41; cutoff points for the prediction of insulin resistance &#40;IR&#41; in school-aged children and preschoolers&#46; The study makes an important contribution to the topic&#44; considering the need to establish cutoff points to use this tool in the Brazilian pediatric population&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">From this perspective&#44; we believe it is very important to warn the authors about a probable mistake in the calculation of TyG&#46; Although the calculation error does not impair the predictive capacity of this method&#44; the proposed cutoff points are significantly altered&#46; This method was proposed by Guerrero-Romero in an article published in 2010&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> and the calculation is described as follows&#58; &#91;ln&#40;fasting triglycerides&#41; &#40;mg&#47;dL&#41;<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>fasting glucose &#40;mg&#47;dL&#41;&#47;2&#93;&#44; and the values found by the authors was 3&#46;7 &#40;values for healthy adults&#41;&#46; However&#44; in another publication by the same authors in 2016&#44;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> we can verify that the indicated calculation is as follows&#58;&#91;ln&#40;fasting triglycerides &#40;mg&#47;dL&#41;<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>fasting glucose &#40;mg&#47;dL&#41;&#93;&#47;2&#44; and the values shown by the authors in this article was 4&#46;5 &#40;values for healthy adult men and women&#41;&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The chart below shows that&#44; according to the formula used&#44; different TyG values will be obtained&#44; since the first formula divides by 2 before performing the logarithmic operation and the second formula divides by 2 after the logarithmic operation of the serum triglyceride and glucose product&#46;<elsevierMultimedia ident="tbl0005"></elsevierMultimedia></p><p id="par0020" class="elsevierStylePara elsevierViewall">Therefore&#44; it is likely that the formula used by the authors who proposed the method is the latter of the two&#44; since the values presented in both articles are between 3&#46;7 and 4&#46;5&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">This error in the formula presentation led other authors&#44;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#8211;6</span></a> including Vieira-Ribeiro et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> to use the first formula to obtain the TyG&#44; achieving much higher values than those shown by the method&#8217;s proponents&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Therefore&#44; we suggest to the authors Vieira-Ribeiro et al&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> that they recalculate the values of TyG based on the second formula&#44; aiming to present more appropriate cutoffs to the original proposal and to allow an appropriate comparison with future studies&#44; which also must adhere to the proper calculation of this index&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare no conflicts of interest&#46;</p></span></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Lopes WA&#44; Oliveira GH&#44; Locateli JC&#44; Sim&#245;es CF&#46; TyG in insulin resistance prediction&#46; J Pediatr &#40;Rio J&#41;&#46; 2020&#59;96&#58;132&#8211;3&#46;</p>"
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Letter to the Editor
TyG in insulin resistance prediction
TyG na predição da resistência à insulina
Wendell Arthur Lopes
Corresponding author
warthurlopes@gmail.com

Corresponding author.
, Gustavo Henrique de Oliveira, João Carlos Locateli, Caroline Ferraz Simões
Universidade Estadual de Maringá (UEM), Centro de Ciências da Saúde, Departamento de Educação Física, Curitiba, PR, Brazil
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        "autoresLista" => "Wendell Arthur Lopes, Gustavo Henrique de Oliveira, Jo&#227;o Carlos Locateli, Caroline Ferraz Sim&#245;es"
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      "es" => array:1 [
        "titulo" => "TyG na predi&#231;&#227;o da resist&#234;ncia &#224; insulina"
      ]
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with interest the article &#8220;The TyG index cutoff point and its association with body adiposity and lifestyle in children&#8221; by Vieira-Ribeiro et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> published in the <span class="elsevierStyleItalic">Jornal de Pediatria&#44;</span> which proposes TyG &#40;triglyceride-glucose &#237;ndex&#41; cutoff points for the prediction of insulin resistance &#40;IR&#41; in school-aged children and preschoolers&#46; The study makes an important contribution to the topic&#44; considering the need to establish cutoff points to use this tool in the Brazilian pediatric population&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">From this perspective&#44; we believe it is very important to warn the authors about a probable mistake in the calculation of TyG&#46; Although the calculation error does not impair the predictive capacity of this method&#44; the proposed cutoff points are significantly altered&#46; This method was proposed by Guerrero-Romero in an article published in 2010&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> and the calculation is described as follows&#58; &#91;ln&#40;fasting triglycerides&#41; &#40;mg&#47;dL&#41;<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>fasting glucose &#40;mg&#47;dL&#41;&#47;2&#93;&#44; and the values found by the authors was 3&#46;7 &#40;values for healthy adults&#41;&#46; However&#44; in another publication by the same authors in 2016&#44;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> we can verify that the indicated calculation is as follows&#58;&#91;ln&#40;fasting triglycerides &#40;mg&#47;dL&#41;<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>fasting glucose &#40;mg&#47;dL&#41;&#93;&#47;2&#44; and the values shown by the authors in this article was 4&#46;5 &#40;values for healthy adult men and women&#41;&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The chart below shows that&#44; according to the formula used&#44; different TyG values will be obtained&#44; since the first formula divides by 2 before performing the logarithmic operation and the second formula divides by 2 after the logarithmic operation of the serum triglyceride and glucose product&#46;<elsevierMultimedia ident="tbl0005"></elsevierMultimedia></p><p id="par0020" class="elsevierStylePara elsevierViewall">Therefore&#44; it is likely that the formula used by the authors who proposed the method is the latter of the two&#44; since the values presented in both articles are between 3&#46;7 and 4&#46;5&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">This error in the formula presentation led other authors&#44;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#8211;6</span></a> including Vieira-Ribeiro et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> to use the first formula to obtain the TyG&#44; achieving much higher values than those shown by the method&#8217;s proponents&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Therefore&#44; we suggest to the authors Vieira-Ribeiro et al&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> that they recalculate the values of TyG based on the second formula&#44; aiming to present more appropriate cutoffs to the original proposal and to allow an appropriate comparison with future studies&#44; which also must adhere to the proper calculation of this index&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare no conflicts of interest&#46;</p></span></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Lopes WA&#44; Oliveira GH&#44; Locateli JC&#44; Sim&#245;es CF&#46; TyG in insulin resistance prediction&#46; J Pediatr &#40;Rio J&#41;&#46; 2020&#59;96&#58;132&#8211;3&#46;</p>"
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                  \t\t\t\t">168&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">88&#46;3&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">4&#46;80&nbsp;\t\t\t\t\t\t\n
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                            3 => "A&#46;Q&#46; Ribeiro"
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                            3 => "E&#46; Mart&#237;nez-Abundis"
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Jornal de Pediatria (English Edition)
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