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Vol. 89. Issue 6.
Pages 554-558 (November - December 2013)
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Vol. 89. Issue 6.
Pages 554-558 (November - December 2013)
ARTIGO ORIGINAL
Open Access
Cow's milk allergy: color Doppler ultrasound findings in infants with hematochezia
Alergia ao leite de vaca: achados do ultrassom com Doppler colorido em neonatos com hematoquezia
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Matias Epifanioa,
Corresponding author
mepifanio@hotmail.com

Corresponding author.
, Jose Vicente Spolidoroa, Nathalia Guarienti Missimab, Ricardo Bernardi Soderc, Pedro Celiny Ramos Garciad, Matteo Baldisserottoc
a Departamento de Gastroenterologia Pediátrica, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brasil
b Escola de Medicina, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brasil
c Departamento de Radiologia, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brasil
d Departamento de Pediatria, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brasil
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Article information
Abstract
Objective

ultrasound (US) has been an important diagnostic tool to identify several cau- ses of gastrointestinal bleeding. Infants with cow's milk allergy (CMA) may present hema- tochezia and the confirmation of the diagnosis can be difficult. The aim of this study is to describe grayscale and color Doppler ultrasound findings in patients with CMA.

Methods

we retrospectively studied 13 infants with CMA. All infants presented severe hematochezia and abdominal pain. All underwent an US study with the diagnosis of aller- gic colitis. This diagnosis was based on clinical findings, recovery after infant or mother exclusion diets in the case of exclusive breastfeeding and positive oral challenge test.

Results

the mean age ranged from 1 to 6 months (mean = 3.53). Seven out of 13 infants (53.8%) had grayscale and color Doppler sonographic repeated after exclusion diet. Twelve out of 13 (92,3%) showed abnormalities at US and CDUS at beginning. The positive findings suggesting colitis were thickened bowel walls and increased vascularity, espe- cially in the descending and sigmoid colon. Colonoscopy and histopathological findings were compatible with allergic colitis. After a diet change the 13 infants recovered and their oral challenge tests were positive.

Conclusion

Doppler US may be very useful in diagnosing secondary colitis, such as CMA, and to exclude several other abdominal diseases that can emulate this disease.

Keywords:
Cow's milk allergy
Colitis
Ultrasound
Resumo
Objetivo

: o ultrassom (US) tem sido uma importante ferramenta de diagnóstico para identificar várias causas de hemorragia gastrointestinal. Neonatos com alergia ao leite de vaca (ALV) podem apresentar hematoquezia, e a confirmação do diagnóstico pode ser difícil. O objetivo deste estudo é descrever achados com ultrassom em escala de cinza e com Doppler colorido em pacientes com ALV.

Métodos

: estudamos, retrospectivamente, 13 neonatos com ALV. Todos eles apresenta- ram hematoquezia severa e dor abdominal e foram submetidos a um estudo com US, com o diagnóstico de colite alérgica. O diagnóstico teve como base os achados clínicos, a recuperação após a dieta de exclusão do neonato ou da mãe, no caso de amamentação exclusiva, e o teste de provocação oral positivo.

Resultados

: a idade média variou de um a seis meses (média = 3,53). Sete dos 13 neona- tos (53,8%) passaram novamente por ultrassonografia em escala de cinza e com Doppler colorido após a dieta de exclusão. Dentre eles, 12 dos 13 (92,3%) mostraram anormali- dades no US e no ultrassom com Doppler colorido (USDC) no início. Os achados positivos que sugeriram colite foram paredes intestinais espessas e aumento na vascularização, principalmente no cólon descendente e sigmoide. Os resultados da colonoscopia e histo- patológicos foram compatíveis com colite alérgica. Após uma mudança na dieta, os 13 neonatos se recuperaram e seus testes de provocação oral foram positivos.

Conclusão

: o US com Doppler pode ser muito útil para diagnosticar a colite secundária, como a ALV, e para excluir várias outras doenças abdominais que podem imitar essa doença.

Palavras-chave:
Alergia ao leite de vaca
Colite
Ultrassom
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Como citar este artigo: Epifanio M, Spolidoro JV, Missima NG, Soder RB, Garcia PC, Baldisserotto M. Cow's milk allergy: color Doppler ultrasound findings in infants with hematochezia. J Pediatr (Rio J). 2013: 89; 554-8.

Copyright © 2013. Brasileira de Pediatria
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