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Vol. 90. Issue 2.
Pages 203-208 (March - April 2014)
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Vol. 90. Issue 2.
Pages 203-208 (March - April 2014)
ARTIGO ORIGINAL
Open Access
Cholelithiasis in obese adolescents treated at an outpatient clinic
Litíase biliar em adolescentes obesos atendidos em ambulatório
Visits
4180
Marília M. de A. Nunesa,b,
Corresponding author
alberto.marilia@uol.com.br

Corresponding author.
, Carla C.M. Medeirosc,d, Luciana R. Silvaa,e
a Medicina e Saúde, Universidade Federal da Bahia (UFBA), Salvador, BA, Brasil
b Universidade Federal de Campina Grande (UFCG), Campina Grande, PB, Brasil
c Saúde da Criança e do Adolescente, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brasil
d Universidade Estadual da Paraiba, Campina Grande, PB, Brasil
e Centro de Estudos de Gastroenterologia e Hepatologia Pediátricas, Universidade Federal da Bahia (UFBA), Salvador, BA, Brasil
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Article information
Abstract
Objective

to describe the frequency and the factors associated with cholelithiasis in obese adolescents.

Methods

this was a cross-sectional descriptive study performed with the adolescents between 10 and 19 years of age treated at the Child and Adolescent Obesity Outpatient Clinic from May to December of 2011. Obesity was defined as body mass index (BMI) > P97, and overweight as BMI > P85, for age and gender, according to the 2007 World Health Organization reference. A questionnaire concerning the presence of signs and symptoms, such as abdominal pain, nausea, vomiting, and intolerance to fat, was administered. Patients were asked about how many kilograms they had lost and in how much time. Laboratory parameters were: triglycerides, total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) levels. Cholelithiasis and hepatic steatosis were diagnosed by ultrasonography.

Results

cholelithiasis was diagnosed in 6.1% (4/66) of the obese adolescents, most of whom were female (3/4); hepatic steatosis was identified in 21.2% (14/66). Intolerance to dietary fat was reported by all patients with cholelithiasis (4/4) and by 17.7% (11/62) of the group without cholelithiasis (p = 0.001). The average weight loss was 6.0 ± 2.9 kg in the patients with cholelithiasis and 3.2 ± 4.8 kg in the group without cholelithiasis (p = 0.04). However, there was no difference between the two groups regarding the time of weight loss (p = 0.11).

Conclusions

cholelithiasis and hepatic steatosis are frequent among obese adolescents and should be investigated systematically in the presence or absence of symptoms.

Keywords:
Obesity
Cholelithiasis
Hepatic steatosis
Children
Adolescent
Resumo
Objetivo

descrever a frequência e os fatores associados à litíase biliar em adolescentes obesos.

Métodos

estudo descritivo tipo corte transversal com adolescentes entre 10 e 19 anos atendidos em ambulatório de obesidade infanto-juvenil, no período de maio a dezembro de 2011. A obesidade foi definida como índice de massa corporal > P97 e o sobrepeso > P85, para idade e sexo, segundo o referencial OMS 2007. Foi aplicado um questionário com dados relacionados à presença de sinais e sintomas, como: dor abdominal, náusea, vômito e intolerância à gordura. Os pacientes foram questionados sobre quantos quilos perderam e em quanto tempo. As variáveis laboratoriais foram: triglicerídeos, colesterol total, lipoproteína de alta densidade (HDL) e lipoproteína de baixa densidade (LDL), aspartato aminotransferase (AST) e alanina aminotransferase (ALT). A litíase biliar e a esteatose hepática foram diagnosticadas por ultrassonografia.

Resultados

a litíase biliar foi diagnosticada em 6,1% (4/66) dos adolescentes obesos, a maioria do sexo feminino (3/4); a esteatose hepática foi identificada em 21,2% (14/66). Intolerância à gordura da dieta foi referida por todos os portadores de litíase biliar (4/4) e por 17,7% (11/62) do grupo sem litíase biliar (0,001). A média de perda de peso foi de 6,0 ± 2,9 kg nos pacientes com litíase biliar e 3,2 ± 4,8 kg no grupo sem litíase biliar (p = 0,04). Porém, em relação ao tempo de perda não houve diferença entre os dois grupos (p = 0,11).

Conclusões

a litíase biliar e a esteatose hepática são frequentes entre adolescentes obesos e devem ser investigadas sistematicamente na presença ou ausência de sintomas.

Palavras-chave:
Obesidade
Litíase biliar
Esteatose hepática
Criança
Adolescente
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Como citar este artigo: Nunes MM, Medeiros CC, Silva LR. Cholelithiasis in obese adolescents treated at an outpatient clinic. J Pediatr (Rio J). 2014;90:203-8.

Estudo realizado na Universidade Federal da Bahia (UFBA), BA, Brasil.

Copyright © 2013. Brasileira de Pediatria
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