Alterações de peso tecidual e histológicas em ratas gestantes submetidas à desnutrição e ao estresse crônico de nicotina, e em seus recém-nascidos

Abstract

 

The effects of a gestational exposure of 80 rats Wistar EPM- 1 to nicotine and undernutrition was examined. The weight and hystological alterations on the liver and lungs was evaluated on the rats and their offspring. A significantly lower weight gain, including liver and lung weight, was observed in nicotinized groups. There was no alterations on the placental weight. Decidual necrosis and hepatic congestion was frequent in the rats. Lung emphysema was found in the neonates.