Estatísticas

 array:25 [
  "pii" => "S2255553618301150"
  "issn" => "22555536"
  "doi" => "10.1016/j.jpedp.2018.06.014"
  "estado" => "S300"
  "fechaPublicacion" => "2019-09-01"
  "aid" => "674"
  "copyright" => "Sociedade Brasileira de Pediatria"
  "copyrightAnyo" => "2019"
  "documento" => "article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "fla"
  "cita" => "J Pediatr (Rio J). 2019;95:531-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 594
    "formatos" => array:3 [
      "EPUB" => 44
      "HTML" => 331
      "PDF" => 219
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:20 [
      "pii" => "S0021755718301700"
      "issn" => "00217557"
      "doi" => "10.1016/j.jped.2018.04.010"
      "estado" => "S300"
      "fechaPublicacion" => "2019-09-01"
      "aid" => "674"
      "copyright" => "Sociedade Brasileira de Pediatria"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "J Pediatr (Rio J). 2019;95:531-7"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 596
        "formatos" => array:3 [
          "EPUB" => 62
          "HTML" => 307
          "PDF" => 227
        ]
      ]
      "en" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
        "titulo" => "Physical fitness and activity&#44; metabolic profile&#44; adipokines and endothelial function in children"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "tieneResumen" => array:2 [
          0 => "en"
          1 => "pt"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "531"
            "paginaFinal" => "537"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "pt" => array:1 [
            "titulo" => "Aptid&#227;o e atividade f&#237;sica&#44; perfil metab&#243;lico&#44; adipocinas e fun&#231;&#227;o endotelial em crian&#231;as"
          ]
        ]
        "contieneResumen" => array:2 [
          "en" => true
          "pt" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figure 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 2021
                "Ancho" => 2653
                "Tamanyo" => 239895
              ]
            ]
            "descripcion" => array:1 [
              "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Correlation between post-occlusive reactive hyperemia &#40;FBF&#41; and &#40;A&#41; leptin and &#40;B&#41; body fat&#44; and correlation between the distance ran in the Yo-Yo test and &#40;C&#41; abdominal circumference and &#40;D&#41; body fat&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jociene Terra da Penha, Fernanda Mussi Gazolla, Cec&#237;lia Noronha de Miranda Carvalho, Isabel Rey Madeira, Fl&#225;vio Rodrigues-J&#250;nior, Elisabeth de Amorim Machado, Fernando Lencastre Sicuro, Paulo Farinatti, Eliete Bouskela, Paulo Ferrez Collett-Solberg"
            "autores" => array:10 [
              0 => array:2 [
                "nombre" => "Jociene Terra da"
                "apellidos" => "Penha"
              ]
              1 => array:2 [
                "nombre" => "Fernanda Mussi"
                "apellidos" => "Gazolla"
              ]
              2 => array:2 [
                "nombre" => "Cec&#237;lia Noronha de Miranda"
                "apellidos" => "Carvalho"
              ]
              3 => array:2 [
                "nombre" => "Isabel Rey"
                "apellidos" => "Madeira"
              ]
              4 => array:2 [
                "nombre" => "Fl&#225;vio"
                "apellidos" => "Rodrigues-J&#250;nior"
              ]
              5 => array:2 [
                "nombre" => "Elisabeth de Amorim"
                "apellidos" => "Machado"
              ]
              6 => array:2 [
                "nombre" => "Fernando Lencastre"
                "apellidos" => "Sicuro"
              ]
              7 => array:2 [
                "nombre" => "Paulo"
                "apellidos" => "Farinatti"
              ]
              8 => array:2 [
                "nombre" => "Eliete"
                "apellidos" => "Bouskela"
              ]
              9 => array:2 [
                "nombre" => "Paulo Ferrez"
                "apellidos" => "Collett-Solberg"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "pt" => array:9 [
          "pii" => "S2255553618301964"
          "doi" => "10.1016/j.jpedp.2018.11.007"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "pt"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2255553618301964?idApp=UINPBA000049"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0021755718301700?idApp=UINPBA000049"
      "url" => "/00217557/0000009500000005/v1_201910010656/S0021755718301700/v1_201910010656/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2255553618301460"
    "issn" => "22555536"
    "doi" => "10.1016/j.jpedp.2018.08.010"
    "estado" => "S300"
    "fechaPublicacion" => "2019-09-01"
    "aid" => "688"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "J Pediatr &#40;Rio J&#41;. 2019;95:538-44"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 854
      "formatos" => array:3 [
        "EPUB" => 83
        "HTML" => 513
        "PDF" => 258
      ]
    ]
    "pt" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Artigo Original</span>"
      "titulo" => "ERICA&#58; smoking is associated with more severe asthma in Brazilian adolescents"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "538"
          "paginaFinal" => "544"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "ERICA&#58; tabagismo est&#225; associado a asma mais grave em adolescentes brasileiros"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 2745
              "Ancho" => 1500
              "Tamanyo" => 155585
            ]
          ]
          "descripcion" => array:1 [
            "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Fluxograma com a sele&#231;&#227;o da amostra&#46; ERICA&#44; Brasil&#44; 2013&#8211;14&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Erica Azevedo de Oliveira Costa Jord&#227;o, Fabio Chigres Kuschnir, Valeska Carvalho Figueiredo, Mara Morelo Rocha F&#233;lix, Thiago Luiz Nogueira da Silva, Maria Cristina Caetano Kuschnir, Katia Vergetti Bloch, Moyses Szklo"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "Erica Azevedo de Oliveira Costa"
              "apellidos" => "Jord&#227;o"
            ]
            1 => array:2 [
              "nombre" => "Fabio Chigres"
              "apellidos" => "Kuschnir"
            ]
            2 => array:2 [
              "nombre" => "Valeska Carvalho"
              "apellidos" => "Figueiredo"
            ]
            3 => array:2 [
              "nombre" => "Mara Morelo Rocha"
              "apellidos" => "F&#233;lix"
            ]
            4 => array:2 [
              "nombre" => "Thiago Luiz Nogueira da"
              "apellidos" => "Silva"
            ]
            5 => array:2 [
              "nombre" => "Maria Cristina Caetano"
              "apellidos" => "Kuschnir"
            ]
            6 => array:2 [
              "nombre" => "Katia Vergetti"
              "apellidos" => "Bloch"
            ]
            7 => array:2 [
              "nombre" => "Moyses"
              "apellidos" => "Szklo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S0021755718305461"
        "doi" => "10.1016/j.jped.2018.05.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0021755718305461?idApp=UINPBA000049"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2255553618301460?idApp=UINPBA000049"
    "url" => "/22555536/0000009500000005/v1_201910010646/S2255553618301460/v1_201910010646/pt/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S2255553619301016"
    "issn" => "22555536"
    "doi" => "10.1016/j.jpedp.2019.05.020"
    "estado" => "S300"
    "fechaPublicacion" => "2019-09-01"
    "aid" => "797"
    "copyright" => "Sociedade Brasileira de Pediatria"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "rev"
    "cita" => "J Pediatr &#40;Rio J&#41;. 2019;95:519-30"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 843
      "formatos" => array:3 [
        "EPUB" => 52
        "HTML" => 537
        "PDF" => 254
      ]
    ]
    "pt" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Artigo de revis&#227;o</span>"
      "titulo" => "Analysis of neonatal mortality risk factors in Brazil&#58; a systematic review and meta&#8208;analysis of observational studies"
      "tienePdf" => "pt"
      "tieneTextoCompleto" => "pt"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "pt"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "519"
          "paginaFinal" => "530"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "pt" => array:1 [
          "titulo" => "An&#225;lise dos fatores de risco na mortalidade neonatal no Brasil&#58; uma revis&#227;o sistem&#225;tica e metan&#225;lise de estudos observacionais"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "pt" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "pt" => true
      ]
      "contienePdf" => array:1 [
        "pt" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 2737
              "Ancho" => 2917
              "Tamanyo" => 602724
            ]
          ]
          "descripcion" => array:1 [
            "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Fluxograma da sele&#231;&#227;o dos estudos&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Felipe Camilo Santiago Veloso, Liliana de Meira Lins Kassar, Michelle Jacintha Cavalcante Oliveira, Telmo Henrique Barbosa de Lima, Nassib Bezerra Bueno, Ricardo Queiroz Gurgel, Samir Buainain Kassar"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Felipe Camilo Santiago"
              "apellidos" => "Veloso"
            ]
            1 => array:2 [
              "nombre" => "Liliana de Meira Lins"
              "apellidos" => "Kassar"
            ]
            2 => array:2 [
              "nombre" => "Michelle Jacintha Cavalcante"
              "apellidos" => "Oliveira"
            ]
            3 => array:2 [
              "nombre" => "Telmo Henrique Barbosa de"
              "apellidos" => "Lima"
            ]
            4 => array:2 [
              "nombre" => "Nassib Bezerra"
              "apellidos" => "Bueno"
            ]
            5 => array:2 [
              "nombre" => "Ricardo Queiroz"
              "apellidos" => "Gurgel"
            ]
            6 => array:2 [
              "nombre" => "Samir Buainain"
              "apellidos" => "Kassar"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "pt"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S0021755718310751"
        "doi" => "10.1016/j.jped.2018.12.014"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0021755718310751?idApp=UINPBA000049"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2255553619301016?idApp=UINPBA000049"
    "url" => "/22555536/0000009500000005/v1_201910010646/S2255553619301016/v1_201910010646/pt/main.assets"
  ]
  "pt" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Artigo original</span>"
    "titulo" => "Physical fitness and activity&#44; metabolic profile&#44; adipokines and endothelial function in children"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "531"
        "paginaFinal" => "537"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Jociene Terra da Penha, Fernanda Mussi Gazolla, Cec&#237;lia Noronha de Miranda Carvalho, Isabel Rey Madeira, Fl&#225;vio Rodrigues&#8208;J&#250;nior, Elisabeth de Amorim Machado, Fernando Lencastre Sicuro, Paulo Farinatti, Eliete Bouskela, Paulo Ferrez Collett&#8208;Solberg"
        "autores" => array:10 [
          0 => array:3 [
            "nombre" => "Jociene Terra da"
            "apellidos" => "Penha"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Fernanda Mussi"
            "apellidos" => "Gazolla"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Cec&#237;lia Noronha de Miranda"
            "apellidos" => "Carvalho"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Isabel Rey"
            "apellidos" => "Madeira"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Fl&#225;vio"
            "apellidos" => "Rodrigues&#8208;J&#250;nior"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Elisabeth de Amorim"
            "apellidos" => "Machado"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "Fernando Lencastre"
            "apellidos" => "Sicuro"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          7 => array:3 [
            "nombre" => "Paulo"
            "apellidos" => "Farinatti"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff0025"
              ]
            ]
          ]
          8 => array:3 [
            "nombre" => "Eliete"
            "apellidos" => "Bouskela"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          9 => array:4 [
            "nombre" => "Paulo Ferrez"
            "apellidos" => "Collett&#8208;Solberg"
            "email" => array:1 [
              0 => "paulosolberg@yahoo.com"
            ]
            "referencia" => array:3 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0005"
              ]
              2 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:5 [
          0 => array:3 [
            "entidad" => "Universidade do Estado do Rio de Janeiro &#40;UERJ&#41;&#44; Laborat&#243;rio de Pesquisas Cl&#237;nicas e Experimentais em Biologia Vascular &#40;Biovasc&#41;&#44; Rio de Janeiro&#44; RJ&#44; Brasil"
            "etiqueta" => "a"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Universidade do Estado do Rio de Janeiro &#40;UERJ&#41;&#44; Faculdade de Ci&#234;ncias M&#233;dicas&#44; Rio de Janeiro&#44; RJ&#44; Brasil"
            "etiqueta" => "b"
            "identificador" => "aff0005"
          ]
          2 => array:3 [
            "entidad" => "Universidade do Estado do Rio de Janeiro &#40;UERJ&#41;&#44; Instituto de Nutri&#231;&#227;o&#44; Rio de Janeiro&#44; RJ&#44; Brasil"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Universidade do Estado do Rio de Janeiro &#40;UERJ&#41;&#44; Laborat&#243;rio de Pesquisas Cl&#237;nicas e Experimentais em Biologia Vascular do Centro Biom&#233;dico &#40;Biovasc&#41;&#44; Rio de Janeiro&#44; RJ&#44; Brasil"
            "etiqueta" => "d"
            "identificador" => "aff0020"
          ]
          4 => array:3 [
            "entidad" => "Universidade do Estado do Rio de Janeiro &#40;UERJ&#41;&#44; Instituto de Educa&#231;&#227;o F&#237;sica e Desporto&#44; Laborat&#243;rio de Atividade F&#237;sica e Promo&#231;&#227;o da Sa&#250;de &#40;Labsau&#41;&#44; Rio de Janeiro&#44; RJ&#44; Brasil"
            "etiqueta" => "e"
            "identificador" => "aff0025"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Autor para correspond&#234;ncia&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Aptid&#227;o e atividade f&#237;sica&#44; perfil metab&#243;lico&#44; adipocinas e fun&#231;&#227;o endotelial em crian&#231;as"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figura 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2473
            "Ancho" => 3167
            "Tamanyo" => 308494
          ]
        ]
        "descripcion" => array:1 [
          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Correla&#231;&#227;o entre a hiperemia reativa p&#243;s&#8208;oclusiva &#40;FBF&#41; e &#40;A&#41; leptina e &#40;B&#41; gordura corporal e correla&#231;&#227;o entre a dist&#226;ncia corrida no teste Yo&#8208;yo e &#40;C&#41; circunfer&#234;ncia abdominal e &#40;D&#41; gordura corporal&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introdu&#231;&#227;o</span><p id="par0005" class="elsevierStylePara elsevierViewall">A preval&#234;ncia da obesidade tem aumentado em todo o mundo e &#233; considerada um problema de sa&#250;de p&#250;blica devido &#224; sua epidemia&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">1</span></a> A causa para esse aumento da preval&#234;ncia parece ser uma redu&#231;&#227;o progressiva no n&#237;vel de atividade f&#237;sica<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">2</span></a> e mudan&#231;as nos h&#225;bitos alimentares com um aumento na ingest&#227;o de energia&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">3</span></a> Uma das principais preocupa&#231;&#245;es com a obesidade &#233; sua associa&#231;&#227;o a v&#225;rios fatores de risco para o desenvolvimento de doen&#231;a cardiovascular&#44; como hipertens&#227;o&#44; dislipidemia&#44; hiperinsulinemia e intoler&#226;ncia &#224; glicose culminando em diabetes <span class="elsevierStyleItalic">mellitus</span> tipo 2 &#40;DM2&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">4</span></a> Apesar de a obesidade afetar todas as faixas et&#225;rias&#44; por muitos anos achava&#8208;se que as complica&#231;&#245;es eram encontradas somente em adultos obesos&#46; V&#225;rios estudos demonstraram agora que a obesidade infantil j&#225; apresenta efeitos negativos sobre a sa&#250;de das crian&#231;as&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">A doen&#231;a cardiovascular &#233; principalmente diagnosticada em uma idade mais avan&#231;ada&#44; por&#233;m os processos insidiosos da aterosclerose&#44; a base da doen&#231;a cardiovascular&#44; podem come&#231;ar na primeira inf&#226;ncia&#46; A disfun&#231;&#227;o endotelial &#233; n&#227;o somente a precursora&#44; mas tamb&#233;m pode ser usada como um marcador do processo ateroscler&#243;tico&#44; pois ela prev&#234; mortalidade e morbidez cardiovascular&#46;<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">5&#44;6</span></a> Isso foi demonstrado em adultos e tamb&#233;m em crian&#231;as e adolescentes obesos&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">7</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">A atividade f&#237;sica &#233; um comportamento definido como qualquer movimento produzido pelos m&#250;sculos esquel&#233;ticos que resulta em um aumento substancial no gasto cal&#243;rico&#44; al&#233;m dos n&#237;veis de repouso&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">8</span></a> A adapta&#231;&#227;o corporal &#224; atividade f&#237;sica tem dois componentes principais&#58; aptid&#227;o f&#237;sica e a pr&#225;tica de fato da atividade f&#237;sica&#46; A pr&#225;tica de atividade f&#237;sica com suas vari&#225;veis &#40;regularidade&#44; dura&#231;&#227;o e intensidade&#41; &#233; o principal determinante da aptid&#227;o f&#237;sica&#44; apesar de n&#227;o ser a &#250;nica&#46; A aptid&#227;o f&#237;sica representa a resposta do corpo &#224; atividade f&#237;sica e &#233; influenciada por outras vari&#225;veis&#44; como idade&#44; sexo&#44; sa&#250;de&#44; gen&#233;tica&#44; e fatores ambientais&#44; como dieta&#44; estresse&#44; tabagismo&#44; consumo de &#225;lcool e passado pessoal&#44; o que significa que algu&#233;m que foi muito ativo no passado pode ter uma melhor aptid&#227;o f&#237;sica agora&#44; mesmo se n&#227;o atualmente ativo&#46; Para a maior parte dos indiv&#237;duos&#44; aumentar a pr&#225;tica de atividade f&#237;sica melhora a aptid&#227;o f&#237;sica<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">9</span></a> e os n&#237;veis elevados de ambas est&#227;o relacionados &#224;s menores taxas de morbidez e mortalidade de v&#225;rias causas&#44; inclusive doen&#231;as cardiovasculares&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">10</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Sabe&#8208;se que&#44; em adultos&#44; a pr&#225;tica regular de atividade f&#237;sica melhora a fun&#231;&#227;o endotelial&#44; reduz a mortalidade e morbidez cardiovascular&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">11</span></a> Nas crian&#231;as&#44; a pr&#225;tica regular de atividade f&#237;sica moderada a vigorosa afeta a fun&#231;&#227;o endotelial&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">12</span></a> Estudos longitudinais demonstraram que&#44; em crian&#231;as obesas&#44; o treinamento f&#237;sico pode melhorar a fun&#231;&#227;o endotelial com rela&#231;&#227;o a altera&#231;&#245;es no &#237;ndice de massa corporal &#40;IMC&#41; ou peso corporal&#46;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">13&#44;14</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">&#201; fundamental entender melhor a fisiologia do aumento do risco cardiovascular que come&#231;a na inf&#226;ncia&#46; Nas crian&#231;as&#44; a pr&#225;tica regular de atividade f&#237;sica &#233; um protetor direto da fun&#231;&#227;o endotelial&#44; independentemente do peso&#44; ou o mecanismo pelo qual a atividade f&#237;sica protege a fun&#231;&#227;o endotelial &#233; somente por meio de controle do peso&#63; O fator da aptid&#227;o f&#237;sica tamb&#233;m precisa ser levado em considera&#231;&#227;o&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">O objetivo deste estudo foi investigar se h&#225; disfun&#231;&#227;o endotelial nas crian&#231;as com peso normal ou sobrepeso e se o perfil metab&#243;lico&#44; as adipocinas e a disfun&#231;&#227;o endotelial seriam mais fortemente associados &#224; aptid&#227;o f&#237;sica ou aos n&#237;veis de atividade f&#237;sica&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Material e m&#233;todos</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Indiv&#237;duos</span><p id="par0035" class="elsevierStylePara elsevierViewall">O estudo foi transversal e envolveu crian&#231;as entre 5 e 12 anos&#44; pr&#233;&#8208;p&#250;beres ou no in&#237;cio da puberdade &#40;est&#225;gio puberal 2 de Tanner&#41;&#46; Foram recrutadas das cl&#237;nicas pedi&#225;tricas e escolas em geral&#46; Foram classificadas como acima do peso ou obesas com base nos crit&#233;rios da OMS&#46; As crian&#231;as com escore z de IMC entre &#43; 1 e &#43; 2 foram consideradas com sobrepeso e com valores acima de &#43; 2 foram consideradas obesas&#46; Para a an&#225;lise estat&#237;stica&#44; as crian&#231;as com sobrepeso e obesas integraram um &#250;nico grupo denominado &#8220;acima do peso&#8221;&#46; O escore z foi calculado com o uso da vers&#227;o 1&#46;04 do <span class="elsevierStyleItalic">software</span> Anthro Plu &#40;OMS&#44; Genebra&#44; Su&#237;&#231;a&#41;&#46; Os crit&#233;rios de exclus&#227;o inclu&#237;ram doen&#231;as que podem interferir na avalia&#231;&#227;o da microcircula&#231;&#227;o&#44; dos marcadores de inflama&#231;&#227;o ou no teste para avaliar o condicionamento f&#237;sico&#44; como doen&#231;as renais&#44; hematol&#243;gicas&#44; hep&#225;ticas&#44; reumatol&#243;gicas&#44; cardiovasculares&#44; respirat&#243;rias&#44; infecciosas e end&#243;crinas&#46; A exposi&#231;&#227;o recente a traumas ou cirurgias tamb&#233;m excluiria os indiv&#237;duos do estudo&#46; O estudo foi aprovado pelo Comit&#234; de &#201;tica de nossa institui&#231;&#227;o e foi obtido o consentimento informado dos pais&#47;respons&#225;veis&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Procedimentos</span><p id="par0040" class="elsevierStylePara elsevierViewall">As crian&#231;as foram avaliadas na Cl&#237;nica de Obesidade Infantil do Servi&#231;o de Endocrinologia Pedi&#225;trica do Hospital Universit&#225;rio&#46; A avalia&#231;&#227;o incluiu uma avalia&#231;&#227;o m&#233;dico&#8208;nutricional&#46; A press&#227;o arterial &#40;Tycos&#44; Welch Allyn Company&#44; Arden&#44; Carolina do Norte&#44; EUA&#41; foi avaliada com a crian&#231;a sentada&#44; seguiu o protocolo&#8208;padr&#227;o&#46; O peso foi verificado com uma balan&#231;a digital &#40;Filizola<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; SP&#44; Brasil&#41; com resolu&#231;&#227;o de 100<span class="elsevierStyleHsp" style=""></span>g&#46; A estatura foi medida com um estadi&#244;metro fixado na parede &#40;Tonelli<span class="elsevierStyleSup">&#174;</span>&#44; Crici&#250;ma&#44; SC&#44; Brasil&#41; com resolu&#231;&#227;o de 1<span class="elsevierStyleHsp" style=""></span>mm&#46; Todas as crian&#231;as foram pesadas e medidas com roupas leves e sem sapatos&#46; A circunfer&#234;ncia da cintura foi medida no ponto m&#233;dio entre a crista il&#237;aca e o arco costal&#46; A circunfer&#234;ncia do quadril foi medida na maior parte dos indiv&#237;duos e foi calculada a raz&#227;o cintura&#47;quadril&#46; A circunfer&#234;ncia do abd&#244;men foi medida dois dedos abaixo do umbigo&#46; Todas as circunfer&#234;ncias foram medidas com uma fita n&#227;o distens&#237;vel&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Todas as amostras de sangue foram coletadas de manh&#227;&#44; ap&#243;s jejum de 12 horas&#46; As amostras foram imediatamente centrifugadas&#44; armazenadas e congeladas a &#8722;80<span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleSup">&#176;</span>C para an&#225;lise posterior&#46; A insulina foi medida com o equipamento gamma C12 com uma fase s&#243;lida para radioimunoensaio Coat&#8208;A&#8208;Count<span class="elsevierStyleSup">125</span> 1 &#40;DPC&#44; Los Angeles&#44; CA&#44; EUA&#41;&#46; A leptina e a adiponectina foram medidas por radioimunoensaio no equipamento gamma C12 com kits que usam o m&#233;todo de duplo anticorpo PEG &#40;Linco Reserach&#44; St&#46; Charles&#44; MO&#44; EUA&#41;&#46; Os n&#237;veis de glicose no soro&#44; colesterol total &#40;CT&#41;&#44; lipoprote&#237;na de alta densidade &#40;HDL&#41; e triglicer&#237;deos &#40;TG&#41; foram analisados imediatamente ap&#243;s a coleta&#46; A HOMA&#8208;RI foi calculada com a multiplica&#231;&#227;o do valor da glicemia de jejum &#40;mmol&#47;L&#41; pela insulina de jejum &#40;&#956;IU&#47;mL&#41; e divis&#227;o por 22&#46;5&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Em uma visita separada&#44; a pletismografia de oclus&#227;o venosa &#40;VOP&#41; foi feita ap&#243;s jejum de no m&#237;nimo quatro horas e sem a ingest&#227;o de cafe&#237;na e pr&#225;tica de exerc&#237;cios&#46; Os indiv&#237;duos continuaram em uma sala com temperatura controlada &#40;20&#8208;22<span class="elsevierStyleHsp" style=""></span>&#176;C na posi&#231;&#227;o supina&#41;&#46; O fluxo sangu&#237;neo do antebra&#231;o &#40;FSA&#41;&#44; em mL&#47;min&#46;&#47;100<span class="elsevierStyleHsp" style=""></span>mL de tecido&#44; foi medido com a VOP &#40;Hokanson&#44; EC6&#44; D&#46;E&#46;&#44; Bellevue&#44; WA&#44; EUA&#41; no antebra&#231;o ou perna n&#227;o dominante &#40;com base no tamanho da crian&#231;a&#41;&#44; mantido no n&#237;vel do cora&#231;&#227;o&#44; com um medidor de tens&#227;o de merc&#250;rio &#40;com sensor sil&#225;stico&#41; posicionado no ter&#231;o proximal do membro em sua circunfer&#234;ncia m&#225;xima&#46; Foram feitas as medi&#231;&#245;es do fluxo b&#225;sico e durante a resposta &#224; hiperemia ap&#243;s oclus&#227;o arterial de tr&#234;s minutos no antebra&#231;o&#46; Foi demonstrado que h&#225; um aumento inicial &#40;1&#8208;2 minutos&#41; no volume do antebra&#231;o&#44; com um leve aumento gradual com a continuidade da isquemia&#46; Como este estudo envolvei crian&#231;as jovens&#44; para reduzir o desconforto do exame foi usado um tempo de oclus&#227;o de tr&#234;s minutos&#46; Houve um intervalo de 20 minutos entre a resposta reativa &#224; hiperemia e a segunda medi&#231;&#227;o do fluxo inicial&#46; A m&#233;dia das quatro primeiras medi&#231;&#245;es em cada per&#237;odo de registro foi usada para an&#225;lise&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">A absorciometria de dupla energia de raios X &#40;DXA&#41; &#40;GE Healthcare<span class="elsevierStyleSup">&#174;</span>&#44; San Francisco&#44; CA&#44; EUA&#41; avaliou a massa corporal total e localizada de gordura e massa magra&#46; A crian&#231;a foi orientada a n&#227;o usar medicamentos e vestir roupas sem acess&#243;rios de metal&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">Os escores de atividade f&#237;sica foram avaliados pelo Question&#225;rio de Atividade F&#237;sica &#40;PAQ&#8208;C&#41;&#44; que investiga&#44; ao perguntar aos pais e &#224;s crian&#231;as&#44; a frequ&#234;ncia e a intensidade da atividade f&#237;sica praticada nos sete dias anteriores &#40;inclusive o fim de semana&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">16</span></a> O question&#225;rio consiste em nove perguntas sobre a pr&#225;tica de esportes e jogos&#59; atividades f&#237;sicas na escola e de lazer&#44; inclusive fins de semana&#46; As perguntas t&#234;m valores que variam de 1 a 5&#44; os escores finais s&#227;o obtidos pelas respostas m&#233;dias&#44; de muito sedent&#225;rio &#40;1&#41; a muito ativo &#40;5&#41;&#46; Esse question&#225;rio foi traduzido para o portugu&#234;s e validado para a popula&#231;&#227;o brasileira e para a faixa et&#225;ria e usado em diferentes estudos&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">17</span></a> As crian&#231;as com escore &#60; 4&#44;0 foram consideradas sedent&#225;rias e as crian&#231;as com escore &#62; 4&#44;0 foram consideradas ativas&#46; O question&#225;rio tamb&#233;m avalia o n&#250;mero de horas gastas diante da televis&#227;o por dia&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">A avalia&#231;&#227;o da aptid&#227;o f&#237;sica foi feita pelo Teste Yo&#8208;yo de Resist&#234;ncia Intermitente N&#237;vel 1 de Hardens&#44;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> que consiste em duas marcas de 20 metros cada da velocidade progressiva da corrida&#44; intercalada por cinco segundos de recupera&#231;&#227;o ativa&#46; O indiv&#237;duo teve&#44; ao correr&#44; de seguir os avisos sonoros emitidos pelo CD player&#46; O sinal teve como base a velocidade em km&#47;h&#44; come&#231;ou em 8<span class="elsevierStyleHsp" style=""></span>km&#47;h e aumentou 0&#44;5<span class="elsevierStyleHsp" style=""></span>km&#47;h a cada minuto&#46; O objetivo foi que o indiv&#237;duo chegasse ao outro canto antes do pr&#243;ximo aviso sonoro&#46; A corrida foi parada quando houve interrup&#231;&#227;o volunt&#225;ria pelo participante por exaust&#227;o ou dois atrasos consecutivos&#46; Todas as crian&#231;as foram orientadas a vestir roupas leves e t&#234;nis durante o teste&#46; Quando os indiv&#237;duos n&#227;o conseguiram correr mais de 240 metros &#40;cinco voltas completas&#41; foram classificados como n&#227;o aptos e quando conseguiram correr mais de 240 metros foram considerados aptos&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">An&#225;lise estat&#237;stica</span><p id="par0070" class="elsevierStylePara elsevierViewall">Os c&#225;lculos preliminares mostraram que&#44; para um poder estat&#237;stico de 80&#37;&#44; o tamanho desej&#225;vel da amostra teria sido 99 indiv&#237;duos&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">A normalidade dos dados e a homocedasticidade foram testadas pelos testes de Kolmogorov&#8208;Smirnov e Shapiro&#8208;Wilk&#46; Foram encontrados alguns pequenos problemas de distribui&#231;&#227;o&#59; portanto&#44; os dados foram analisados em uma abordagem n&#227;o param&#233;trica&#46; As diferen&#231;as nos par&#226;metros antropom&#233;tricos e fisiol&#243;gicos entre os tr&#234;s grupos foram testados por meio de uma Anova n&#227;o param&#233;trica de Kruskal&#8208;Wallis&#46; O teste <span class="elsevierStyleItalic">post hoc</span> de Dunn foi usado para identificar diferen&#231;as espec&#237;ficas entre os grupos&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">As compara&#231;&#245;es entre os grupos eutr&#243;fico e acima do peso &#40;grupos sobrepeso &#43; obesos&#41; foram feitas por meio do teste U de Mann&#8208;Whitney&#46; As correla&#231;&#245;es entre as vari&#225;veis entre os grupos foram obtidas por meio do R&#243; de Spearman&#44; bem como as an&#225;lises de correla&#231;&#227;o parcial&#46; As estat&#237;sticas descritivas e comparativas foram feitas com a vers&#227;o 8 do Statistica &#40;StatSoft Inc&#46;&#44; Tulsa&#44; OK&#44; EUA&#41; e os testes de correla&#231;&#227;o foram feitos com a vers&#227;o 3&#46;0&#46;2 do pacote PPCOR do R Linguagem e Ambiente para Computa&#231;&#227;o Estat&#237;stica &#40;R Foundation for Statistical Computing&#44; Viena&#44; &#193;ustria&#41;&#46; O n&#237;vel de relev&#226;ncia estat&#237;stica foi estabelecido em alfa 0&#44;05&#46;</p></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Resultados</span><p id="par0085" class="elsevierStylePara elsevierViewall">Participaram deste estudo 62 crian&#231;as&#44; 31 meninos&#46; Com base no IMC&#44; 27 eram eutr&#243;ficos&#44; dez estavam acima do peso e 25 estavam obesos&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Conforme esperado&#44; as vari&#225;veis antropom&#233;tricas &#40;escore z de IMC&#44; circunfer&#234;ncia da cintura&#44; raz&#227;o cintura&#47;quadril e gordura corporal&#41;&#44; triglicer&#237;deos&#44; colesterol LDL&#44; HOMA&#8208;RI e leptina foram significativamente maiores no grupo de crian&#231;as obesas e acima do peso &#40;individualmente ou agrupados como o grupo acima do peso&#41; em compara&#231;&#227;o com o grupo de eutr&#243;ficos &#40;p &#60; 0&#44;01&#41;&#46; Os n&#237;veis de colesterol HDL e adiponectina estavam mais elevados no grupo de eutr&#243;ficos em compara&#231;&#227;o com o grupo de obesos e com excesso de peso &#40;p &#60; 0&#44;01&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0095" class="elsevierStylePara elsevierViewall">Na an&#225;lise da fun&#231;&#227;o endotelial&#44; a vasodilata&#231;&#227;o mediada pelo fluxo &#40;VMF&#41; ap&#243;s hiperemia foi maior no grupo de eutr&#243;ficos em compara&#231;&#227;o com os indiv&#237;duos obesos e com excesso de peso&#44; demonstrou uma fun&#231;&#227;o endotelial prejudicada nestes &#40;p &#60; 0&#44;05&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46; As altera&#231;&#245;es na VMF ap&#243;s hiperemia foram fortemente correlacionadas negativamente &#224; leptina &#40;r&#243; &#61; &#8722;0&#44;56&#59; p &#61; 0&#44;0001&#41; e ao percentual de gordura corporal &#40;r&#243; &#61; &#8722;0&#44;49&#44; p &#61; 0&#44;0001&#41; conforme mostrado na <a class="elsevierStyleCrossRef" href="#fig0005">figura 1</a>A e B&#44; respectivamente&#44; demonstraram que quanto maior os n&#237;veis de leptina ou gordura corporal&#44; menor a resposta endotelial &#224; hiperemia&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0100" class="elsevierStylePara elsevierViewall">N&#227;o houve diferen&#231;a nos n&#237;veis de atividade f&#237;sica entre os grupos medidos pelo PAQ&#8208;C&#46; Trinta crian&#231;as foram classificadas como ativas &#40;oito eram obesas&#41; e 30 como sedent&#225;rias&#46; Duas crian&#231;as n&#227;o responderam o question&#225;rio PAQ&#8208;C&#46; Com base no teste Yo&#8208;yo&#44; 32 crian&#231;as foram consideradas fisicamente aptas &#40;seis obesas&#41; e 28 n&#227;o aptas&#46; Duas crian&#231;as n&#227;o conclu&#237;ram o teste Yo&#8208;yo&#46; N&#227;o houve correla&#231;&#227;o estatisticamente significativa entre o PAQ&#8208;C ou o teste Yo&#8208;yo e hiperemia reativa na VMF&#46; Houve uma forte correla&#231;&#227;o negativa entre o teste Yo&#8208;yo e a circunfer&#234;ncia da cintura &#40;r&#243; &#61; &#8722;0&#44;50&#44; p &#61; 0&#44;0001&#41; e o percentual de gordura corporal &#40;r&#243; &#61; &#8722;0&#44;57&#44; p &#60; 0&#44;0001&#41;&#44; <a class="elsevierStyleCrossRef" href="#fig0005">figura 1</a>C e D respectivamente&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Como uma das perguntas foi tentar diferenciar entre a influ&#234;ncia do peso corporal e da aptid&#227;o f&#237;sica e a pr&#225;tica de atividade f&#237;sica&#44; foi feita uma an&#225;lise de correla&#231;&#227;o de tr&#234;s formas&#46; Primeiro&#44; investigamos se houve uma correla&#231;&#227;o entre o perfil metab&#243;lico ou os marcadores de inflama&#231;&#227;o e a aptid&#227;o f&#237;sica ou a pr&#225;tica de atividade f&#237;sica&#46; Ap&#243;s isso&#44; fizemos o ajuste para o escore z de IMC para ver se a correla&#231;&#227;o persistiu&#46; A HOMA&#8208;RI e a leptina foram inversamente correlacionadas ao escore z do PAQ&#8208;C&#44; ao passo que a adiponectina foi positivamente correlacionada&#46; Ap&#243;s os ajustes para o escore z de IMC &#40;acrescentando o escore z de IMC &#224; an&#225;lise de correla&#231;&#227;o&#44; como uma terceira vari&#225;vel&#41;&#44; essas correla&#231;&#245;es n&#227;o foram mantidas&#44; demonstrou&#8208;se que as correla&#231;&#245;es iniciais provavelmente dependeram do escore z de IMC &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabela 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0110" class="elsevierStylePara elsevierViewall">Na an&#225;lise de correla&#231;&#227;o com o teste Yo&#8208;yo com o perfil metab&#243;lico e ajustado para o escore z de IMC&#44; o HDL foi correlacionado ao teste Yo&#8208;yo &#40;r&#243; &#61; 0&#44;41&#59; p &#61; 0&#44;01&#41; e essa correla&#231;&#227;o continuou&#44; apesar de mais fraca&#44; quando ajustada para o escore z de IMC &#40;r&#243; &#61; 0&#44;28&#59; p &#61; 0&#44;03&#41;&#44; demonstrou&#8208;se que a obesidade explica alguma correla&#231;&#227;o entre a dist&#226;ncia corrida no teste Yo&#8208;yo e o HDL&#44; por&#233;m n&#227;o &#233; o &#250;nico fator que influencia essa correla&#231;&#227;o&#46; Ao analisar os resultados do teste Yo&#8208;yo e a HOMA&#8208;RI &#40;r&#243; &#61; &#8722;0&#44;38&#59; p &#61; 0&#44;01&#41;&#59; &#40;r&#243; &#61; 0&#44;02&#59; p &#61; 0&#44;92&#41; e leptina &#40;r&#243; &#61; &#8722;0&#44;40&#59; p &#61; 0&#44;01&#41;&#59; &#40;r&#243; &#61; &#8722;0&#44;04&#59; p &#61; 0&#44;82&#41;&#44; houve uma correla&#231;&#227;o inicial&#44; por&#233;m ele n&#227;o foi mantido com o ajuste para o escore z de IMC &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabela 2</a>&#41;&#44; demonstrou&#8208;se que a correla&#231;&#227;o inicial provavelmente dependeu do escore z de IMC&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Discuss&#227;o</span><p id="par0115" class="elsevierStylePara elsevierViewall">Este estudo avaliou a rela&#231;&#227;o entre a aptid&#227;o f&#237;sica&#44; a atividade f&#237;sica&#44; o perfil metab&#243;lico e a fun&#231;&#227;o endotelial em crian&#231;as jovens obesas&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Os c&#225;lculos preliminares mostraram que o tamanho desej&#225;vel da amostra teria sido 99 indiv&#237;duos&#44; por&#233;m&#44; devido a diferentes fatores&#44; somente 56 indiv&#237;duos participaram do estudo&#44; que nos deixa com um poder de 55&#37;&#46; Contudo&#44; mesmo com um tamanho da amostra inferior ao ideal&#44; este estudo mostrou diferen&#231;as nos n&#237;veis de aptid&#227;o f&#237;sica entre as crian&#231;as obesas e n&#227;o obesas e que as pessoas jovens obesas t&#234;m uma predisposi&#231;&#227;o &#224; doen&#231;a ateroscler&#243;tica&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Os n&#237;veis de colesterol LDL&#44; a HOMA&#8208;RI e a leptina&#44; conhecidos marcadores de doen&#231;a cardiovascular&#44; foram mais elevados no grupo de obesos&#46; Ao mesmo tempo&#44; os n&#237;veis s&#233;ricos de colesterol HDL e leptina foram menores&#46; Esse perfil metab&#243;lico indica que mesmo nessa faixa et&#225;ria jovem essas crian&#231;as j&#225; tinham maior risco de desenvolver doen&#231;a cardiovascular no futuro&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a></p><p id="par0130" class="elsevierStylePara elsevierViewall">A disfun&#231;&#227;o endotelial &#233; considerada essencial para o desenvolvimento de doen&#231;a cardiovascular e sua detec&#231;&#227;o precoce pode ser importante no desenvolvimento de estrat&#233;gias de interven&#231;&#227;o em crian&#231;as que t&#234;m maior risco de doen&#231;a ateroscler&#243;tica&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">20</span></a> Em nossos achados&#44; houve altera&#231;&#245;es na fun&#231;&#227;o endotelial em crian&#231;as obesas em compara&#231;&#227;o com os outros grupos&#46; As figuras 1A e B reiteram esses achados&#44; mostram forte correla&#231;&#227;o inversa entre a VMF e a leptina&#44; um marcador de obesidade e a VMF em compara&#231;&#227;o com a gordura corporal&#46; As crian&#231;as jovens com aumento da gordura corporal ou n&#237;veis elevados de leptina &#40;marcador de obesidade&#41; j&#225; t&#234;m fun&#231;&#227;o endotelial prejudicada&#46; Um estudo observacional sobre a rela&#231;&#227;o dos n&#237;veis de atividade f&#237;sica em crian&#231;as de 5&#8208;10 anos&#44; classificadas como moderadamente ativas&#44; encontrou uma correla&#231;&#227;o entre os n&#237;veis de atividade f&#237;sica e a VMF&#44; conclui&#8208;se que seria importante come&#231;ar um programa de atividade f&#237;sica na inf&#226;ncia para influenciar a sa&#250;de arterial&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">21</span></a> Alguns estudos de interven&#231;&#227;o mostraram a efici&#234;ncia da pr&#225;tica de exerc&#237;cio f&#237;sico para melhorar a vasodilata&#231;&#227;o dependente do endot&#233;lio de crian&#231;as e adolescentes obesos&#44;<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">22&#44;23</span></a> o que aumenta a disponibilidade de &#243;xido n&#237;trico&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">24</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">O conceito de &#8220;gordo&#44; por&#233;m saud&#225;vel&#8221; diz que&#44; em adultos&#44; a aptid&#227;o f&#237;sica pode ser t&#227;o importante quanto a quantidade de massa gorda em termos de risco cardiovascular&#46; A dificuldade de investigar esse conceito em crian&#231;as &#233; que a literatura mostra que as crian&#231;as obesas gastam menos tempo praticando certa atividade f&#237;sica do que as crian&#231;as n&#227;o obesas e&#44;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">25</span></a> como esperado&#44; isso parece afetar sua composi&#231;&#227;o corporal e reduzir sua aptid&#227;o f&#237;sica&#46;<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">26</span></a> Um estudo com crian&#231;as entre 7&#8208;11 anos constatou que a obesidade afetou a resist&#234;ncia&#44; a velocidade e a agilidade negativamente e eles foram inversamente associados &#224; aptid&#227;o f&#237;sica&#46;<a class="elsevierStyleCrossRef" href="#bib0285"><span class="elsevierStyleSup">27</span></a> Por outro lado&#44; parece que o estilo de vida sedent&#225;rio em si aumenta os riscos de desenvolver aterosclerose e outras doen&#231;as prematuramente&#44;<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">28</span></a> pois um estudo mostrou que mesmo crian&#231;as saud&#225;veis e com peso normal classificadas como tendo baixa aptid&#227;o cardiorrespirat&#243;ria apresentaram pior perfil metab&#243;lico e inflamat&#243;rio do que as com melhor aptid&#227;o f&#237;sica&#46;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">29</span></a></p><p id="par0140" class="elsevierStylePara elsevierViewall">Apesar de nosso estudo n&#227;o ter mostrado diferen&#231;a na aptid&#227;o f&#237;sica ou atividade f&#237;sica quando comparado com crian&#231;as com sobrepeso e crian&#231;as eutr&#243;ficas&#44; constatamos uma correla&#231;&#227;o inversa entre a dist&#226;ncia corrida no teste Yo&#8208;yo e o percentual de gordura corporal e a circunfer&#234;ncia da cintura&#44; demonstrou&#8208;se que a aptid&#227;o f&#237;sica&#44; mais a pr&#225;tica de atividade f&#237;sica&#44; j&#225; influencia a composi&#231;&#227;o corporal nessa faixa et&#225;ria jovem&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">Para tentar determinar o que foi mais importante para a sa&#250;de cardiovascular das crian&#231;as&#44; a adiposidade ou o sedentarismo&#44; verificamos correla&#231;&#245;es entre a atividade f&#237;sica ou a aptid&#227;o f&#237;sica com os marcadores de DCV&#44; ajustando para o escore z de IMC&#46; Houve uma correla&#231;&#227;o parcial inicial entre a atividade f&#237;sica e o HDL&#44; HOMA&#8208;RI&#44; adiponectina e leptina&#44; por&#233;m essa correla&#231;&#227;o n&#227;o foi mantida quando ajustada para o escore z de IMC&#44; sugeriu&#8208;se uma prov&#225;vel influ&#234;ncia mais forte da massa corporal sobre essas vari&#225;veis&#46; O mesmo foi observado na aptid&#227;o f&#237;sica com rela&#231;&#227;o &#224;s vari&#225;veis HOMA&#8208;RI e leptina&#46; Similarmente a nossos achados em um estudo&#44; as crian&#231;as obesas e com peso normal apresentaram aptid&#227;o cardiorrespirat&#243;ria inversamente associada &#224; HOMA&#8208;RI&#44; por&#233;m essa correla&#231;&#227;o desapareceu quando ajustada para a idade&#44; sexo e massa gorda&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">30</span></a> Contudo&#44; em nosso estudo&#44; a correla&#231;&#227;o com o HDL foi mantida mesmo ap&#243;s ajuste para a massa corporal&#44; sugeriu&#8208;se que a influ&#234;ncia da aptid&#227;o f&#237;sica sobre o perfil lip&#237;dico &#233; mais importante do que do sobrepeso&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">Nosso estudo n&#227;o mostrou diferen&#231;as nos n&#237;veis de atividade f&#237;sica entre as crian&#231;as obesas e n&#227;o obesas&#44; apesar de ter mostrado diferen&#231;as na aptid&#227;o f&#237;sica&#46; Este estudo tamb&#233;m mostrou que as crian&#231;as obesas apresentaram maiores n&#237;veis de colesterol LDL e leptina&#44; menor colesterol HDL e adiponectina e j&#225; apresentam sinais de disfun&#231;&#227;o endotelial&#44; sugeriu&#8208;se fortemente uma predisposi&#231;&#227;o &#224; doen&#231;a ateroscler&#243;tica&#46; Apesar de algumas dessas diferen&#231;as terem sido principalmente relacionadas ao excesso de peso&#44; os n&#237;veis de colesterol HDL est&#227;o correlacionados &#224; aptid&#227;o f&#237;sica&#44; independentemente do IMC&#46; N&#227;o houve correla&#231;&#227;o entre esses marcadores e a atividade f&#237;sica habitual&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Financiamento</span><p id="par0155" class="elsevierStylePara elsevierViewall">Bolsa de estudos da Funda&#231;&#227;o Carlos Chagas Filho de Amparo &#224; Pesquisa do Estado do Rio de Janeiro &#40;Faperj&#41;&#46; Jociene Terra da Penha foi patrocinada por uma bolsa de estudos do Conselho Nacional de Desenvolvimento Cient&#237;fico e Tecnol&#243;gico &#40;CNPq&#41;&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Conflitos de interesse</span><p id="par0160" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:11 [
        0 => array:3 [
          "identificador" => "xres1250763"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Objectives"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Method"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusion"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1159711"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres1250764"
          "titulo" => "Resumo"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Objetivos"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "M&#233;todo"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclus&#227;o"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec1159710"
          "titulo" => "Palavras&#8208;chave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introdu&#231;&#227;o"
        ]
        5 => array:3 [
          "identificador" => "sec0010"
          "titulo" => "Material e m&#233;todos"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Indiv&#237;duos"
            ]
            1 => array:2 [
              "identificador" => "sec0020"
              "titulo" => "Procedimentos"
            ]
            2 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "An&#225;lise estat&#237;stica"
            ]
          ]
        ]
        6 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Resultados"
        ]
        7 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Discuss&#227;o"
        ]
        8 => array:2 [
          "identificador" => "sec0040"
          "titulo" => "Financiamento"
        ]
        9 => array:2 [
          "identificador" => "sec0045"
          "titulo" => "Conflitos de interesse"
        ]
        10 => array:1 [
          "titulo" => "Refer&#234;ncias"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2018-02-08"
    "fechaAceptado" => "2018-04-25"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1159711"
          "palabras" => array:6 [
            0 => "Obesity"
            1 => "Endothelial dysfunction"
            2 => "Cardiovascular disease"
            3 => "Obesity"
            4 => "Overweight"
            5 => "Pediatrics"
          ]
        ]
      ]
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras&#8208;chave"
          "identificador" => "xpalclavsec1159710"
          "palabras" => array:6 [
            0 => "Obesidade"
            1 => "Disfun&#231;&#227;o endotelial"
            2 => "Doen&#231;a cardiovascular"
            3 => "Obesidade"
            4 => "Sobrepeso"
            5 => "Pediatria"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objectives</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The prevalence of obesity is increasing&#46; The aim of this study was to investigate if there is endothelial dysfunction in children with normal or excess weight&#44; and whether the metabolic profile&#44; adipokines&#44; and endothelial dysfunction would be more strongly associated with physical fitness or with physical activity levels&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Cross&#8208;sectional study involving children aged 5&#8211;12 years&#46; The evaluation included venous occlusion plethysmography&#44; serum levels of adiponectin&#44; leptin and insulin&#44; lipid profile&#44; physical activity score &#40;PAQ&#8208;C questionnaire&#41;&#44; and physical fitness evaluation &#40;Yo&#8208;Yo test&#41;&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A total of 62 children participated in this study&#46; Based on the body mass index&#44; 27 were eutrophic&#44; 10 overweight and 25 obese&#46; Triglycerides&#44; LDL cholesterol&#44; HOMA&#8208;IR&#44; and leptin were higher in the obese and excess&#8208;weight groups compared to the eutrophic group &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; HDL cholesterol and adiponectin levels were higher in the eutrophic group compared to the obese and excess&#8208;weight groups &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#46; Flow&#8208;mediated vasodilation after hyperemia was higher in the eutrophic group in comparison to obese and excess&#8208;weight subjects &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; There was no difference in the physical activity levels among groups measured by PAQ&#8208;C&#46; The Yo&#8208;Yo test was significantly associated with HDL cholesterol &#40;rho<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;0&#46;41&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#41;&#44; and this association remained after adjusting for body mass index <span class="elsevierStyleItalic">z</span>&#8208;score &#40;rho<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;28&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;03&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">This study showed that endothelial dysfunction is already present in obese children&#44; suggesting a predisposition to atherosclerotic disease&#46; Moreover&#44; HDL cholesterol levels were correlated with physical fitness&#44; regardless of body mass index&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objectives"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Method"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusion"
          ]
        ]
      ]
      "pt" => array:3 [
        "titulo" => "Resumo"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivos</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">A preval&#234;ncia da obesidade est&#225; aumentando&#46; O objetivo deste estudo foi investigar se h&#225; disfun&#231;&#227;o endotelial nas crian&#231;as com peso normal ou excesso de peso e se o perfil metab&#243;lico&#44; as adipocinas e a disfun&#231;&#227;o endotelial seriam mais fortemente associados &#224; aptid&#227;o f&#237;sica ou aos n&#237;veis de atividade f&#237;sica&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudo transversal que envolve crian&#231;as de 5&#8208;12 anos&#46; A avalia&#231;&#227;o incluiu pletismografia de oclus&#227;o venosa&#44; n&#237;veis s&#233;ricos de adiponectina&#44; leptina&#44; insulina e lipidograma&#44; escore de atividade f&#237;sica &#40;question&#225;rio PAQ&#8208;C&#41; e avalia&#231;&#227;o da aptid&#227;o f&#237;sica &#40;teste Yo&#8208;yo&#41;&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Um total de 62 crian&#231;as participou deste estudo&#46; Com base no &#237;ndice de massa corporal&#44; 27 eram eutr&#243;ficos&#44; 10 estavam acima do peso e 25 estavam obesos&#46; Os n&#237;veis de triglicer&#237;deos&#44; colesterol LDL&#44; HOMA-RI e leptina estavam mais elevados nas crian&#231;as obesas e com excesso de peso que o grupo de eutr&#243;ficos &#40;p &#60; 0&#44;01&#41;&#46; Os n&#237;veis de colesterol HDL e adiponectina estavam mais elevados no grupo de eutr&#243;ficos em compara&#231;&#227;o ao grupo de obesos e com excesso de peso &#40;p &#60; 0&#44;01&#41;&#46; A vasodilata&#231;&#227;o mediada pelo fluxo ap&#243;s hiperemia foi maior no grupo de eutr&#243;ficos em compara&#231;&#227;o aos indiv&#237;duos obesos e com excesso de peso &#40;p &#60; 0&#44;05&#41;&#46; N&#227;o houve nenhuma diferen&#231;a nos n&#237;veis de atividade f&#237;sica entre os grupos medidos pelo PAQ-C&#46; O teste de ida e volta foi significativamente associado ao colesterol HDL &#40;r&#243; &#61; &#8722;0&#44;41&#59; p &#61; 0&#44;01&#41; e essa associa&#231;&#227;o continuou ap&#243;s ajustar o escore z do &#237;ndice de massa corporal &#40;r&#243; &#61; 0&#44;28&#59; p &#61; 0&#44;03&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#227;o</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Este estudo mostrou que a disfun&#231;&#227;o endotelial j&#225; est&#225; presente nas crian&#231;as obesas&#44; sugeriu uma predisposi&#231;&#227;o &#224; doen&#231;a ateroscler&#243;tica&#46; Al&#233;m disso&#44; os n&#237;veis de colesterol HDL foram correlacionados &#224; aptid&#227;o f&#237;sica&#44; independentemente do &#237;ndice de massa corporal&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Objetivos"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "M&#233;todo"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclus&#227;o"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0020">Como citar este artigo&#58; Penha JT&#44; Gazolla FM&#44; Carvalho CN&#44; Madeira IR&#44; Rodrigues&#8208;J&#250;nior F&#44; Machado EA&#44; et al&#46; Physical fitness and activity&#44; metabolic profile&#44; adipokines and endothelial function in children&#46; J Pediatr &#40;Rio J&#41;&#46; 2019&#59;95&#58;531&#8211;7&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figura 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2473
            "Ancho" => 3167
            "Tamanyo" => 308494
          ]
        ]
        "descripcion" => array:1 [
          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Correla&#231;&#227;o entre a hiperemia reativa p&#243;s&#8208;oclusiva &#40;FBF&#41; e &#40;A&#41; leptina e &#40;B&#41; gordura corporal e correla&#231;&#227;o entre a dist&#226;ncia corrida no teste Yo&#8208;yo e &#40;C&#41; circunfer&#234;ncia abdominal e &#40;D&#41; gordura corporal&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Tabela 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Tabela "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Resultados expressos como mediana &#40;quartil inferior&#8208;superior&#41;&#46; O grupo acima do peso representa as crian&#231;as com sobrepeso e obesas combinadas&#46;</p><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">HDL&#44; lipoprote&#237;na de alta densidade&#59; IL&#8208;6&#44; interleucina &#8211; 6&#59; IMC&#44; &#237;ndice de massa corporal&#59; LDL&#44; lipoprote&#237;na de baixa densidade&#59; PAQ&#8208;C&#44; Question&#225;rio de Atividade F&#237;sica para Crian&#231;as&#59; RCQ&#44; Raz&#227;o Cintura&#47;Quadril&#59; TG&#44; triglicer&#237;deos&#59; VMF&#44; Vasodilata&#231;&#227;o Mediada pelo Fluxo&#46;</p><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Compara&#231;&#227;o entre eutr&#243;pico x obeso</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Eutr&#243;ficas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Obesas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Acima do peso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Idade &#40;anos&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;0 &#40;6&#44;0&#8208;10&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;0 &#40;7&#44;0&#8208;11&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;0 &#40;8&#44;0&#8208;9&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;4656&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;0 &#40;8&#44;0&#8208;10&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Escore z de IMC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;33 &#40;&#8722;1&#44;0&#8208;0&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;35 &#40;1&#44;11&#8208;1&#44;52&#41;<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;85 &#40;2&#44;46&#8208;3&#44;78&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;58 &#40;1&#44;85&#8208;3&#44;37&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60; 0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Circunfer&#234;ncia da cintura &#40;cm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">57 &#40;53&#44;5&#8208;62&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">69&#44;05 &#40;63&#44;9&#8208;74&#44;2&#41;<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">84&#44;0 &#40;80&#44;0&#8208;91&#44;0&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">82 &#40;72&#8208;89&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60; 0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">RCQ&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;82 &#40;0&#44;80&#8208;0&#44;83&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;8 &#40;0&#44;78&#8208;0&#44;82&#41;<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;85 &#40;0&#44;82&#8208;0&#44;88&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;84 &#40;0&#44;8&#8208;0&#44;88&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#37; gordura&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">25&#44;2 &#40;20&#44;5&#8208;31&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">35&#44;05 &#40;29&#44;8&#8208;39&#44;8&#41;<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">45&#44;2 &#40;41&#44;8&#8208;48&#44;6&#41;<a class="elsevierStyleCrossRefs" href="#tblfn0005"><span class="elsevierStyleSup">a&#44;c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">43&#44;3 &#40;37&#44;2&#8208;47&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60; 0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Escore z do PAQ&#8208;C&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;39 &#40;3&#44;59&#8208;4&#44;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;5 &#40;3&#44;0&#8208;4&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;8 &#40;3&#44;1&#8208;4&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;1684&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;75 &#40;3&#44;01&#8208;4&#44;67&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Teste Yo&#8208;yo &#40;m&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">250 &#40;240&#8208;320&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">240 &#40;160&#8208;300&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">160 &#40;100&#8208;220&#41;<a class="elsevierStyleCrossRefs" href="#tblfn0005"><span class="elsevierStyleSup">a&#44;c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">195 &#40;115&#8208;240&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TG &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">59&#44;5 &#40;44&#8208;73&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">85 &#40;60&#8208;109&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">100 &#40;80&#8208;121&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">93&#44;5 &#40;74&#44;5&#8208;114&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">LDL &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">88 &#40;76&#8208;107&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">94 &#40;84&#8208;140&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">102 &#40;92&#8208;113&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;09&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">102 &#40;87&#8208;114&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HDL &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">55&#44;5 &#40;47&#8208;61&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">45 &#40;45&#8208;47&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">44 &#40;37&#8208;51&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">45 &#40;38&#44;5&#8208;50&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HOMA&#8208;RI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;1 &#40;1&#44;0&#8208;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;4 &#40;1&#44;7&#8208;4&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;64 &#40;2&#44;7&#8208;6&#44;8&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;3 &#40;2&#44;2&#8208;5&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Adiponectina &#40;&#956;g&#47;mL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#44;3 &#40;11&#44;1&#8208;15&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;57 &#40;7&#44;5&#8208;12&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;91 &#40;5&#44;5&#8208;11&#44;0&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8 &#40;5&#44;6&#8208;11&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Leptina &#40;ng&#47;mL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;6 &#40;2&#44;9&#8208;5&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;87 &#40;4&#44;9&#8208;30&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29&#44;8 &#40;25&#44;7&#8208;43&#44;4&#41;<a class="elsevierStyleCrossRefs" href="#tblfn0005"><span class="elsevierStyleSup">a&#44;c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60; 0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29&#44;6 &#40;13&#44;0&#8208;37&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60; 0&#44;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">VMF &#40;mL&#47;min&#47;100<span class="elsevierStyleHsp" style=""></span>mL tecido&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;6 &#40;1&#44;9&#8208;3&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;2 &#40;2&#44;0&#8208;3&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;15 &#40;1&#44;8&#8208;3&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;6645&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;15 &#40;1&#44;9&#8208;3&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hiperemia na VMF &#40;mL&#47;min&#47;100<span class="elsevierStyleHsp" style=""></span>mL tecido&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;8 &#40;4&#44;9&#8208;6&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;92 &#40;4&#44;5&#8208;5&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;7 &#40;3&#44;4&#8208;5&#44;7&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;71 &#40;3&#44;7&#8208;5&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2139625.png"
              ]
            ]
          ]
          "notaPie" => array:3 [
            0 => array:3 [
              "identificador" => "tblfn0005"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0005">eutr&#243;pico x sobrepeso&#46;</p>"
            ]
            1 => array:3 [
              "identificador" => "tblfn0010"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0010">sobrepeso x obeso</p>"
            ]
            2 => array:3 [
              "identificador" => "tblfn0015"
              "etiqueta" => "c"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0015">N&#237;vel de signific&#226;ncia &#40;p &#60; 0&#44;05&#41;&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "pt" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Compara&#231;&#227;o entre crian&#231;as eutr&#243;ficas&#44; com sobrepeso e obesas com rela&#231;&#227;o aos dados antropom&#233;tricos&#44; atividade f&#237;sica&#44; aptid&#227;o f&#237;sica&#44; perfil metab&#243;lico&#44; adipocinas e VMF</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Tabela 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Tabela "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar1145" class="elsevierStyleSimplePara elsevierViewall">VMF&#44; Vasodilata&#231;&#227;o Mediada pelo Fluxo&#46;</p><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">N&#237;vel de signific&#226;ncia &#40;p &#60; 0&#44;05&#41;&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">r&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">r&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">r&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">r&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TG &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;97&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HDL &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;67&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HOMA&#8208;RI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;42&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;92&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Adiponectina &#40;&#956;g&#47;mL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;42&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Leptina &#40;ng&#47;mL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;42&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hiperemia na VMF&#40;mL&#47;min&#47;100<span class="elsevierStyleHsp" style=""></span>mL tecido&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8722;0&#44;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2139626.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "pt" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Correla&#231;&#227;o entre o PAQ&#8208;C&#44; o teste Yo&#8208;yo e o perfil metab&#243;lico&#44; as adipocinas e a hiperemia na VMF&#46; Corre&#231;&#227;o parcial com escore z do PAQ&#8208;C Ajuste para o escore z de IMC Correla&#231;&#227;o parcial com Teste Yo&#8208;yo</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Refer&#234;ncias"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:30 [
            0 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Childhood obesity&#58; causes and consequences"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46; Sahoo"
                            1 => "B&#46; Sahoo"
                            2 => "A&#46;K&#46; Choudhury"
                            3 => "N&#46;Y&#46; Sofi"
                            4 => "R&#46; Kumar"
                            5 => "A&#46;S&#46; Bhadoria"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/2249-4863.154628"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Family Med Prim Care"
                        "fecha" => "2015"
                        "volumen" => "4"
                        "paginaInicial" => "187"
                        "paginaFinal" => "192"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25949965"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Systematic review of sedentary behavior and health indicators in school&#8208;aged children and youth"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;S&#46; Tremblay"
                            1 => "A&#46;G&#46; LeBlanc"
                            2 => "M&#46;E&#46; Kho"
                            3 => "T&#46;J&#46; Saunders"
                            4 => "R&#46; Larouche"
                            5 => "R&#46;C&#46; Colley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1479-5868-8-98"
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Behav Nutr Phys Act"
                        "fecha" => "2011"
                        "volumen" => "8"
                        "paginaInicial" => "98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21936895"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of childhood obesity in Europe"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "B&#46; Livingstone"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur J Pediatr"
                        "fecha" => "2000"
                        "volumen" => "159"
                        "paginaInicial" => "S14"
                        "paginaFinal" => "S34"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Childhood and adolescent obesity&#46; Prevalence and significance"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46;M&#46; Styne"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Pediatr Clin N Am"
                        "fecha" => "2001"
                        "volumen" => "48"
                        "paginaInicial" => "823"
                        "paginaFinal" => "854"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Endothelial dysfunction&#58; a marker of atherosclerotic risk"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;O&#46; Bonetti"
                            1 => "L&#46;O&#46; Lerman"
                            2 => "A&#46; Lerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arteriocler Thromb Vasc Biol"
                        "fecha" => "2003"
                        "volumen" => "23"
                        "paginaInicial" => "168"
                        "paginaFinal" => "175"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46;G&#46; Reddy"
                            1 => "R&#46;N&#46; Nair"
                            2 => "H&#46;M&#46; Sheehan"
                            3 => "J&#46;M&#46; Hodgson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/0735-1097(94)90627-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Coll Cardiol"
                        "fecha" => "1994"
                        "volumen" => "23"
                        "paginaInicial" => "833"
                        "paginaFinal" => "843"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8106687"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body mass index is directly associated with biomarkers of angiogenesis and inflammation in children and adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Siervo"
                            1 => "D&#46; Ruggiero"
                            2 => "R&#46; Sorice"
                            3 => "T&#46; Nutile"
                            4 => "M&#46; Aversano"
                            5 => "M&#46; Iafusco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.nut.2011.06.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nutrition"
                        "fecha" => "2012"
                        "volumen" => "28"
                        "paginaInicial" => "262"
                        "paginaFinal" => "266"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22113066"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aerobic fitness and the metabolic syndrome in children and adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;C&#46; Eisenmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Peadiatr"
                        "fecha" => "2007"
                        "volumen" => "96"
                        "paginaInicial" => "1723"
                        "paginaFinal" => "1729"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cardiorespiratory fitness relates more strongly than physical activity to cardiovascular disease risk factors in healthy children and adolescents&#58; the European Youth Heart Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Hurtig-Wennolof"
                            1 => "J&#46;R&#46; Ruiz"
                            2 => "M&#46; Harro"
                            3 => "M&#46; Sjostrom"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/HJR.0b013e32808c67e3"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Cardiovasc Prev Rehabil"
                        "fecha" => "2007"
                        "volumen" => "14"
                        "paginaInicial" => "575"
                        "paginaFinal" => "581"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17667650"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fat or fit&#58; what is more important&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46; Hainer"
                            1 => "H&#46; Toplak"
                            2 => "V&#46; Stich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Diabetes Care"
                        "fecha" => "2009"
                        "volumen" => "2"
                        "paginaInicial" => "392"
                        "paginaFinal" => "397"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prognostic importance of endothelial dysfunction and carotid atheroma burden in patients with coronary artery disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46;Y&#46; Chan"
                            1 => "G&#46;B&#46; Mancini"
                            2 => "L&#46; Kuramoto"
                            3 => "M&#46; Schulzer"
                            4 => "J&#46; Frohlich"
                            5 => "A&#46; Ignaszewski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/s0735-1097(03)00927-6"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Coll Cardiol"
                        "fecha" => "2003"
                        "volumen" => "42"
                        "paginaInicial" => "1037"
                        "paginaFinal" => "1043"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13678927"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Physical activity and cardiorespiratory fitness&#44; but not sedentary behavior&#44; are associated with carotid intima&#8208;media thickness in obese adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; Ascenso"
                            1 => "A&#46; Palmeira"
                            2 => "L&#46;M&#46; Pedro"
                            3 => "S&#46; Martins"
                            4 => "H&#46; Fonseca"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00431-015-2654-x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Pediatr"
                        "fecha" => "2016"
                        "volumen" => "175"
                        "paginaInicial" => "391"
                        "paginaFinal" => "398"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26490566"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of exercise training in obese children and adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46; Watts"
                            1 => "E&#46; Davis"
                            2 => "T&#46; Jones"
                            3 => "D&#46;J&#46; Green"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2165/00007256-200535010-00001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Sports Med"
                        "fecha" => "2005"
                        "volumen" => "35"
                        "paginaInicial" => "1"
                        "paginaFinal" => "18"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15651909"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Influence of cardiorespiratory fitness and other precursors on cardiovascular disease and all&#8208;cause mortality in men and women"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;N&#46; Blair"
                            1 => "J&#46;B&#46; Kampert"
                            2 => "H&#46;W&#46; Kohl 3rd"
                            3 => "C&#46;E&#46; Barlow"
                            4 => "C&#46;A&#46; Macera"
                            5 => "R&#46;S&#46; Paffenbarger Jr&#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "1996"
                        "volumen" => "276"
                        "paginaInicial" => "205"
                        "paginaFinal" => "210"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8667564"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Homeostasis model assessment&#58; insulin resistance and beta&#8208;cell function from fasting plasma glucose and insulin concentrations in man"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D&#46;R&#46; Mathews"
                            1 => "J&#46;P&#46; Hosker"
                            2 => "A&#46;S&#46; Rudenski"
                            3 => "B&#46;A&#46; Naylor"
                            4 => "D&#46;F&#46; Treacher"
                            5 => "R&#46;C&#46; Tunner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/bf00280883"
                      "Revista" => array:6 [
                        "tituloSerie" => "Diabetologia"
                        "fecha" => "1985"
                        "volumen" => "28"
                        "paginaInicial" => "412"
                        "paginaFinal" => "419"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3899825"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Measuring general levels of physical activity&#58; preliminary evidence for the Physical Activity Questionnaire for Older Children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46;R&#46; Crocker"
                            1 => "D&#46;A&#46; Bailey"
                            2 => "R&#46;A&#46; Faulkner"
                            3 => "K&#46;C&#46; Kowalski"
                            4 => "R&#46; McGrath"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/00005768-199710000-00011"
                      "Revista" => array:6 [
                        "tituloSerie" => "Med Sci Sports Exerc"
                        "fecha" => "1997"
                        "volumen" => "29"
                        "paginaInicial" => "1344"
                        "paginaFinal" => "1349"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9346166"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Overweight and physical inactivity in children living in favelas in the metropolitan region of Recife&#44; Brazil"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;G&#46; Alves"
                            1 => "P&#46;P&#46; Siqueira"
                            2 => "J&#46;N&#46; Figueiroa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Pediatr &#40;Rio J&#41;"
                        "fecha" => "2009"
                        "volumen" => "85"
                        "paginaInicial" => "67"
                        "paginaFinal" => "71"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Yo&#8208;Yo Intermittent Endurance Test&#8208;Level 1 to monitor changes in aerobic fitness in pre&#8208;pubertal boys"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "L&#46; Fernandes"
                            1 => "P&#46; Krustrup"
                            2 => "G&#46; Silva"
                            3 => "A&#46; Rebelo"
                            4 => "J&#46; Oliveira"
                            5 => "J&#46; Brito"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur J Sport Sci"
                        "fecha" => "2015"
                        "volumen" => "22"
                        "paginaInicial" => "1"
                        "paginaFinal" => "6"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adipocytokines in relation to cardiovascular disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46; Van de Voorde"
                            1 => "B&#46; Pauwels"
                            2 => "C&#46; Boydens"
                            3 => "K&#46; Decaluw&#233;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.metabol.2013.06.004"
                      "Revista" => array:6 [
                        "tituloSerie" => "Metabolism"
                        "fecha" => "2013"
                        "volumen" => "62"
                        "paginaInicial" => "1513"
                        "paginaFinal" => "1521"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23866981"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of exercise training on vascular function in obese children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Watts"
                            1 => "P&#46; Beye"
                            2 => "A&#46; Siafarikas"
                            3 => "G&#46; O&#8217;Driscoll"
                            4 => "T&#46;W&#46; Jones"
                            5 => "E&#46;A&#46; Davis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jpeds.2004.02.027"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Pediatr"
                        "fecha" => "2004"
                        "volumen" => "144"
                        "paginaInicial" => "620"
                        "paginaFinal" => "625"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15126996"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Correlation of habitual physical activity levels with flow&#8208;mediated dilation of the brachial artery in 5&#8211;10 year old children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;A&#46; Abbott"
                            1 => "M&#46;A&#46; Harkness"
                            2 => "P&#46;S&#46; Davies"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/s0021-9150(01)00566-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Atherosclerosis"
                        "fecha" => "2002"
                        "volumen" => "160"
                        "paginaInicial" => "233"
                        "paginaFinal" => "239"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11755942"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Improvement of early vascular changes and cardiovascular risk factors in obese children after a six&#8208;month exercise program"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46;A&#46; Meyer"
                            1 => "G&#46; Kundt"
                            2 => "U&#46; Lenschow"
                            3 => "P&#46; Schuff-Werner"
                            4 => "W&#46; Kienast"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jacc.2006.07.035"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Coll Cardiol"
                        "fecha" => "2006"
                        "volumen" => "48"
                        "paginaInicial" => "1865"
                        "paginaFinal" => "1870"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17084264"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Exercise training normalizes vascular dysfunction and improves central adiposity in obese adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Watts"
                            1 => "P&#46; Beye"
                            2 => "A&#46; Siafarikas"
                            3 => "E&#46;A&#46; Davis"
                            4 => "T&#46;W&#46; Jones"
                            5 => "G&#46; O&#8217;Driscoll"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jacc.2004.01.032"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Coll Cardiol"
                        "fecha" => "2004"
                        "volumen" => "43"
                        "paginaInicial" => "1823"
                        "paginaFinal" => "1827"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15145107"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Four weeks of cycle training increases basal production of nitric oxide from the forearm"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "B&#46;A&#46; Kingwell"
                            1 => "B&#46; Sherrard"
                            2 => "G&#46;L&#46; Jennings"
                            3 => "A&#46;M&#46; Dart"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1152/ajpheart.1997.272.3.H1070"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Physiol"
                        "fecha" => "1997"
                        "volumen" => "272"
                        "paginaInicial" => "H1070"
                        "paginaFinal" => "H1077"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9087577"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Physical activity patterns in nonobese and obese children assessed using minute&#8208;by&#8208;minute accelerometry"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Page"
                            1 => "A&#46;R&#46; Cooper"
                            2 => "E&#46; Stamatakis"
                            3 => "L&#46;J&#46; Foster"
                            4 => "E&#46;C&#46; Crowne"
                            5 => "M&#46; Sabin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Obes &#40;Lond&#41;"
                        "fecha" => "2005"
                        "volumen" => "29"
                        "paginaInicial" => "1070"
                        "paginaFinal" => "1076"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adiposity is related to decrements in cardiorespiratory fitness in obese and normal&#8208;weight children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;D&#46; Tsiros"
                            1 => "A&#46;M&#46; Coates"
                            2 => "P&#46;R&#46; Howe"
                            3 => "J&#46; Walkley"
                            4 => "A&#46;P&#46; Hills"
                            5 => "R&#46;E&#46; Wood"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/ijpo.12037"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Obes"
                        "fecha" => "2016"
                        "volumen" => "11"
                        "paginaInicial" => "144"
                        "paginaFinal" => "150"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25950151"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Deleterious effects of obesity on physical fitness in pre&#8208;pubertal children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Ceschia"
                            1 => "S&#46; Giacomini"
                            2 => "S&#46; Santarossa"
                            3 => "M&#46; Rugo"
                            4 => "D&#46; Salvadego"
                            5 => "A&#46; Da Ponte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1080/17461391.2015.1030454"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Sport Sci"
                        "fecha" => "2016"
                        "volumen" => "16"
                        "paginaInicial" => "271"
                        "paginaFinal" => "278"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25866877"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mini review&#58; physical activity and fitness and its relations to cardiovascular disease risk factors in children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46; Froberg"
                            1 => "L&#46;B&#46; Andersen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Obes &#40;Lond&#41;"
                        "fecha" => "2005"
                        "volumen" => "2"
                        "paginaInicial" => "S34"
                        "paginaFinal" => "S39"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0295"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Non&#8208;traditional markers of metabolic risk in prepubertal children with different levels of cardiorespiratory fitness"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46;J&#46; Llorente-Cantarero"
                            1 => "J&#46;L&#46; P&#233;rez-Navero"
                            2 => "J&#46; de Dios Benitez-Sillero"
                            3 => "M&#46;C&#46; Mu&#241;oz-Villanueva"
                            4 => "M&#46; Guill&#233;n-del Castillo"
                            5 => "M&#46; Gil-Campos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Public Health Nutr"
                        "fecha" => "2012"
                        "volumen" => "10"
                        "paginaInicial" => "1827"
                        "paginaFinal" => "1834"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0300"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Elevated total and central adiposity and low physical activity are associated with insulin resistance in children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46; Krekoukia"
                            1 => "G&#46;P&#46; Nassis"
                            2 => "G&#46; Psarra"
                            3 => "K&#46; Skenderi"
                            4 => "G&#46;P&#46; Chrousos"
                            5 => "L&#46;S&#46; Sidossis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.metabol.2006.09.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "Metabolism"
                        "fecha" => "2007"
                        "volumen" => "56"
                        "paginaInicial" => "206"
                        "paginaFinal" => "213"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17224334"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "pt"
  "url" => "/22555536/0000009500000005/v1_201910010646/S2255553618301150/v1_201910010646/pt/main.assets"
  "Apartado" => array:4 [
    "identificador" => "16682"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Artigos originais"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/22555536/0000009500000005/v1_201910010646/S2255553618301150/v1_201910010646/pt/main.pdf?idApp=UINPBA000049&text.app=https://jped.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2255553618301150?idApp=UINPBA000049"
]