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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Curvas de distribui&#231;&#227;o normal com valor de corte &#40;VC&#41; para colesterol n&#227;o HDL em meninos &#40;A&#44; B&#44; C&#41; e meninas &#40;D&#44; E&#44; F&#41; obesos e n&#227;o obesos de acordo com a classifica&#231;&#227;o fornecida pelo IMC&#44; RCE e PGC&#44; respectivamente&#46;</p> <p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">IMC&#44; &#237;ndice de massa corporal&#59; RCE&#44; raz&#227;o cintura&#47;estatura&#59; PGC&#44; percentual de gordura corporal&#46;</p>"
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associa&#231;&#227;o entre obesidade e dislipidemia&#44; estudos em todo o mundo confirmaram que o perfil lip&#237;dico desfavor&#225;vel &#233; mais prevalente em crian&#231;as e adolescentes com sobrepeso e obesas do que as com peso normal&#46;<a class="elsevierStyleCrossRefs" href="#bib0170"><span class="elsevierStyleSup">4&#8211;7</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Dados do Estudo do Cora&#231;&#227;o de Bogalusa<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">8</span></a> mostraram que&#44; conforme o aumento do IMC para a idade&#44; h&#225; um aumento acentuado na propor&#231;&#227;o de crian&#231;as com m&#250;ltiplos fatores de risco metab&#243;lico&#46; Apesar de o IMC ser reconhecido como importante indicador de progn&#243;stico de diabetes e doen&#231;a do cora&#231;&#227;o&#44;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">9</span></a> sua adequa&#231;&#227;o como marcador fenot&#237;pico de adiposidade foi contestada&#44; pois o IMC n&#227;o estima composi&#231;&#227;o corporal e n&#227;o pode diferenciar entre gordura e m&#250;sculo em crian&#231;as&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">10</span></a> Al&#233;m disso&#44; estudos sugeriram que a raz&#227;o cintura&#47;estatura &#40;RCE&#41; foi melhor vari&#225;vel preditora de risco cardiovascular e metab&#243;lico&#44;<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">11&#8211;14</span></a> apesar de a heterogeneidade substancial entre os estudos garantir investiga&#231;&#245;es adicionais&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Recentemente&#44; uma metan&#225;lise dos estudos que investigam a associa&#231;&#227;o entre a gordura corporal avaliada por absorciometria de raio X de dupla energia &#40;Dexa&#41; &#8211; o padr&#227;o de base para avaliar composi&#231;&#227;o corporal &#8211; com IMC ou RCE revelou que ambos os indicadores de situa&#231;&#227;o do peso podem ser &#250;teis na defini&#231;&#227;o de adiposidade entre crian&#231;as e adolescentes&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">16</span></a> Contudo&#44; pouco se sabe se esses indicadores de situa&#231;&#227;o do peso s&#227;o equivalentes como substitutos da gordura corporal para discriminar indiv&#237;duos com perfil lip&#237;dico desfavor&#225;vel&#46; Portanto&#44; este estudo buscou investigar se o IMC e a RCE s&#227;o semelhantes ao percentual de gordura corporal &#40;PGC&#41; no que diz respeito &#224; identifica&#231;&#227;o de crian&#231;as e adolescentes obesas com perfil lip&#237;dico desfavor&#225;vel&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">M&#233;todos</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Modelo do estudo e sele&#231;&#227;o da amostra</span><p id="par0020" class="elsevierStylePara elsevierViewall">Estudo transversal conduzido com dados de uma amostra de conveni&#234;ncia&#46; As vari&#225;veis de interesse foram retiradas da base de dados do projeto intitulada &#8220;Determinantes da eleva&#231;&#227;o da press&#227;o arterial em crian&#231;as e adolescentes de diferentes ancestralidades&#8221;&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">A amostra foi decorrente de um projeto social chamado Esta&#231;&#227;o Conhecimento em Serra&#44; Esp&#237;rito Santo&#44; Brasil&#46; Na &#233;poca da coleta de dados&#44; cerca de 900 crian&#231;as e adolescentes foram registradas nessa institui&#231;&#227;o&#44; que fornece apoio acad&#234;mico gratuito e oportunidade para praticar esportes e desenvolver atividades art&#237;sticas&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">De fevereiro de 2014 a abril de 2016&#44; os participantes compareceram &#224; Cl&#237;nica de Investiga&#231;&#227;o Cardiovascular &#40;CIC&#41; localizada no Hospital Universit&#225;rio Cassiano Ant&#244;nio de Moraes &#40;Hucam&#8208;Ufes&#41; para ser submetidos a exames cl&#237;nicos e laboratoriais&#46; Os exames foram feitos na manh&#227; ap&#243;s jejum noturno&#46; Todos os dados foram coletados em uma &#250;nica visita por uma equipe treinada previamente certificada pelo investigador s&#234;nior &#40;JGM&#41;&#46; Para a presente an&#225;lise&#44; foram exclu&#237;dos 16 participantes com dados ausentes na base de dados&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">O projeto foi aprovado pelo Comit&#234; de &#201;tica do Centro de Ci&#234;ncias da Sa&#250;de &#40;n&#176; de registro&#58; 30385014&#46;8&#46;0000&#46;5060&#41; e o consentimento informado por escrito foi obtido dos pais ou respons&#225;veis legais antes da participa&#231;&#227;o&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Antropometria</span><p id="par0040" class="elsevierStylePara elsevierViewall">O peso foi obtido com uma balan&#231;a eletr&#244;nica com precis&#227;o de 0&#44;05<span class="elsevierStyleHsp" style=""></span>kg &#40;Toledo&#44; SP&#44; Brasil&#41; em indiv&#237;duos descal&#231;os que usavam apenas roupas &#237;ntimas&#46; O peso foi obtido em um estadi&#244;metro de parede &#40;Estadi&#244;metro Seca&#59; Seca GmBH &#38; Co&#44; Hamburgo&#44; Alemanha&#41; com precis&#227;o de 0&#44;1<span class="elsevierStyleHsp" style=""></span>cm&#46; O percentual de gordura corporal &#40;PGC&#41; foi medido por an&#225;lise de imped&#226;ncia bioel&#233;trica multifrequ&#234;ncia &#40;MF&#8208;BIA8&#44; InBody 230&#44; Bioespace&#44; Coreia do Sul&#41;&#46; O IMC foi calculado como raz&#227;o entre peso e estatura ao quadrado&#46; A circunfer&#234;ncia da cintura foi medida no topo da crista il&#237;aca&#46; A RCE foi obtida como raz&#227;o entre a circunfer&#234;ncia da cintura e a estatura&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Como o ac&#250;mulo de gordura corporal &#233; influenciado por idade e sexo&#44; o percentil &#40;P&#41; do IMC para a idade para meninos e meninas foi fornecido de acordo com as normas do Centro de Controle e Preven&#231;&#227;o de Doen&#231;as para Crian&#231;as e Adolescentes entre dois e 19 anos&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">17</span></a> Tamb&#233;m foram obtidos o <span class="elsevierStyleItalic">p</span> do PGC e o <span class="elsevierStyleItalic">p</span> da RCE espec&#237;ficos para a idade e o sexo correspondentes&#46; Al&#233;m disso&#44; os mesmos indiv&#237;duos foram classificados em n&#227;o obesos &#40;<span class="elsevierStyleItalic">p</span> &#60; 95&#41; ou obesos &#40;<span class="elsevierStyleItalic">p</span> &#8805; 95&#41; com o PGC e os indicadores de situa&#231;&#227;o do peso&#44; o IMC e a RCE&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Exame bioqu&#237;mico</span><p id="par0050" class="elsevierStylePara elsevierViewall">A coleta de sangue foi obtida por flebotomia ap&#243;s jejum noturno &#40;8&#8208;14<span class="elsevierStyleHsp" style=""></span>h&#41; e enviada para um laborat&#243;rio central &#40;Laborat&#243;rio Tommasi&#44; Vit&#243;ria&#44; Brasil&#41; para determinar as concentra&#231;&#245;es s&#233;ricas de colesterol total&#44; LDL&#8208;C&#44; HDL&#8208;C&#44; TG e glicemia de jejum&#46; O LDL&#8208;C foi calculado pela equa&#231;&#227;o de Friedwald para aqueles com TG &#8804; 400<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#46; O colesterol n&#227;o HDL foi calculado como colesterol total menos HDL&#8208;C&#46; O valor de corte para colesterol n&#227;o HDL &#40;144<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41; foi obtido da I Diretriz Brasileira de Preven&#231;&#227;o Cardiovascular&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> Todas as dosagens foram feitas com kits comercialmente dispon&#237;veis&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Medi&#231;&#227;o da press&#227;o arterial</span><p id="par0055" class="elsevierStylePara elsevierViewall">A press&#227;o arterial sist&#243;lica &#40;PAS&#41;&#44; press&#227;o arterial diast&#243;lica &#40;PAD&#41; e frequ&#234;ncia card&#237;aca &#40;FC&#41; foram obtidas com um dispositivo autom&#225;tico validado com o manguito posicionado no bra&#231;o esquerdo &#40;Omrom 705CP&#44; Intellisense&#44; Jap&#227;o&#41; ap&#243;s um per&#237;odo de descanso de cinco minutos sentado&#41;&#46; Tr&#234;s medidas foram consideradas&#44; com descanso de um minuto entre cada&#46; O resultado da primeira medi&#231;&#227;o foi desconsiderado e calculamos a m&#233;dia das medi&#231;&#245;es 2 e 3&#46; Em um caso de varia&#231;&#227;o de mais de 5<span class="elsevierStyleHsp" style=""></span>mmHg entre 2 e 3&#44; foi feita uma quarta medi&#231;&#227;o e calculamos a m&#233;dia das duas medi&#231;&#245;es mais pr&#243;ximas de 5<span class="elsevierStyleHsp" style=""></span>mmHg&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">An&#225;lise estat&#237;stica</span><p id="par0060" class="elsevierStylePara elsevierViewall">As caracter&#237;sticas da amostra foram expressas como m&#233;dia &#177; desvio&#8208;padr&#227;o&#46; As diferen&#231;as entre os sexos em caracter&#237;sticas gerais foram testadas com o teste <span class="elsevierStyleItalic">t</span> de duas amostras&#46; As caracter&#237;sticas antropom&#233;tricas foram comparadas entre obesos e n&#227;o obesos com o teste <span class="elsevierStyleItalic">t</span> de duas amostras e a associa&#231;&#227;o entre obesidade e fra&#231;&#245;es lip&#237;dicas foi testada com Ancova e idade&#44; PAS e FC como covari&#225;veis&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">A normalidade de todos os dados foi confirmada com o teste de Kolmogorov&#8208;Smirnov&#46; Os dados foram adequados para projetar curvas normalizadas para comparar os escores z calculados com o corte padronizado&#46; Considerando as propriedades da distribui&#231;&#227;o normal padr&#227;o&#44; desvios&#8208;padr&#227;o &#40;DP&#41; de 3&#44;00 para a esquerda ou direito de uma m&#233;dia que abrange 99&#44;76&#37; de uma popula&#231;&#227;o&#46; As m&#233;dias e a distribui&#231;&#227;o ajustada &#40;escore z&#41; foram usadas para identificar a propor&#231;&#227;o de crian&#231;as e adolescentes com colesterol n&#227;o HDL acima do valor de corte &#40;144<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41;&#46; Os obesos foram comparados com os pares n&#227;o obesos em todos os tr&#234;s indicadores&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Todos os procedimentos estat&#237;sticos foram feitos com o pacote estat&#237;stico SPSS 21&#46;0 &#40;SPSS Inc&#46;&#44; Chicago&#44; Illinois&#44; EUA&#41; e curvas normalizadas para colesterol n&#227;o HDL foram projetadas com GraphPad Prism 6&#46;01 &#40;GraphPad Software&#44; Inc&#46; CA&#44; EUA&#41;&#46; O poder estat&#237;stico foi calculado com o <span class="elsevierStyleItalic">software</span> R &#40;vers&#227;o 3&#46;2&#46;2&#44; R Foundation for Statistical Computing&#44; Viena&#44; &#193;ustria&#41;&#46; A relev&#226;ncia estat&#237;stica foi estabelecida em <span class="elsevierStyleItalic">p</span> &#60; 0&#44;05&#46;</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Resultados</span><p id="par0075" class="elsevierStylePara elsevierViewall">As caracter&#237;sticas gerais da amostra estratificada por sexo est&#227;o na <a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#46; Como esperado&#44; maior estatura foi observada entre meninos em compara&#231;&#227;o com as meninas&#46; Apesar de a RCE ter sido semelhante entre os sexos&#44; IMC e PGC foram maiores nas meninas em compara&#231;&#227;o com os meninos &#40;<span class="elsevierStyleItalic">p</span> &#60; 0&#44;05&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0080" class="elsevierStylePara elsevierViewall">A <a class="elsevierStyleCrossRef" href="#tbl0010">tabela 2</a> mostra as caracter&#237;sticas antropom&#233;tricas e o perfil lip&#237;dico entre meninos classificados como obesos ou n&#227;o obesos de acordo com os tr&#234;s indicadores&#46; A idade foi semelhante e&#44; como esperado&#44; o IMC&#44; a RCE e o PGC foram maiores nos indiv&#237;duos obesos em compara&#231;&#227;o com os n&#227;o obesos em todos os indicadores&#46; Entre esses indiv&#237;duos classificados de acordo com o IMC&#44; maior LDL&#8208;C &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;003&#41;&#44; colesterol n&#227;o HDL &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;001&#41; e TG &#40;<span class="elsevierStyleItalic">p</span> &#60; 0&#44;001&#41;&#44; juntamente com menor HDL&#8208;C &#40;<span class="elsevierStyleItalic">p</span> &#60; 0&#44;001&#41;&#44; foram observados em obesos em compara&#231;&#227;o com n&#227;o obesos&#44; mesmo ap&#243;s ajuste para idade&#44; PAS e FC&#46; Resultados semelhantes foram observados quando os indiv&#237;duos foram classificados de acordo com a RCE&#44; al&#233;m de maior colesterol total em obesos em compara&#231;&#227;o com n&#227;o obesos &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;005&#41;&#46; Al&#233;m disso&#44; colesterol&#44; LDL&#8208;C&#44; n&#227;o HDL e TG foram maiores &#40;todos <span class="elsevierStyleItalic">p</span> &#60; 0&#44;001&#41; em obesos em compara&#231;&#227;o com n&#227;o obesos da classifica&#231;&#227;o fornecida pela PGC&#44; ao passo que o HDL&#8208;C foi semelhante entre os grupos&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">A <a class="elsevierStyleCrossRef" href="#tbl0015">tabela 3</a> mostra as caracter&#237;sticas antropom&#233;tricas e o perfil lip&#237;dico entre meninas classificadas como obesas ou n&#227;o obesas de acordo com os tr&#234;s indicadores&#46; A compara&#231;&#227;o entre meninas obesas e n&#227;o obesas em todos os indicadores &#233; disposta com ajuste para idade&#44; PAS e FC&#46; Foram observados maior TG &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;001&#41; e menor HDL&#8208;C &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;025&#41; em meninas obesas em compara&#231;&#227;o com n&#227;o obesas classificadas pelo IMC&#44; ao passou que n&#227;o foi detectada diferen&#231;a significativa entre os grupos para colesterol&#44; LDL&#8208;C e colesterol n&#227;o HDL&#46; Ao usar RCE como indicador&#44; n&#227;o foi detectada diferen&#231;a significativa entre as meninas obesas e n&#227;o obesas para qualquer fra&#231;&#227;o de lip&#237;dios&#46; Por outro lado&#44; o colesterol total &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;021&#41;&#44; LDL&#8208;C &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;003&#41;&#44; colesterol n&#227;o HDL &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;001&#41; e TG &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;003&#41; foram maiores e HDL&#8208;C foi menor &#40;<span class="elsevierStyleItalic">p</span> &#61; 0&#44;013&#41; em meninas obesas em compara&#231;&#227;o com meninas n&#227;o obesas classificadas por PGC&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0090" class="elsevierStylePara elsevierViewall">As curvas de normalidade sobrepostas que mostram a distribui&#231;&#227;o do colesterol n&#227;o HDL entre meninos obesos e n&#227;o obesos de acordo com os indicadores de situa&#231;&#227;o do peso e PGC s&#227;o mostradas nos gr&#225;ficos da <a class="elsevierStyleCrossRef" href="#fig0005">figura 1</a>&#46; A forma das curvas de normalidade revela que n&#227;o apenas as m&#233;dias&#44; mas tamb&#233;m a distribui&#231;&#227;o de colesterol n&#227;o HDL foi diferente em meninas obesas em compara&#231;&#227;o com n&#227;o obesas&#46; Em todos os indicadores&#44; pode&#8208;se observar um valor justo de sobreposi&#231;&#227;o &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>A&#8208;C&#41;&#44; embora haja uma maior mudan&#231;a para a direita na curva de distribui&#231;&#227;o de colesterol n&#227;o HDL de meninos obesos quando o PGC foi o indicador de refer&#234;ncia &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>C&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0095" class="elsevierStylePara elsevierViewall">Entre as meninas&#44; as curvas de distribui&#231;&#227;o normal de colesterol n&#227;o HDL de indiv&#237;duos obesos e n&#227;o obesos s&#227;o quase completamente sobrepostas com o IMC &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>D&#41; e a RCE como indicadores &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>E&#41;&#46; Por outro lado&#44; uma grande mudan&#231;a para a direita na curva de distribui&#231;&#227;o de colesterol n&#227;o HDL de meninas obesas foi observada quando o PGC foi usado para discriminar obesas e n&#227;o obesas &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>F&#41;&#46; Para fins de compara&#231;&#227;o&#44; entre os meninos classificados como obesos pela RCE&#44; a diferen&#231;a matem&#225;tica da m&#233;dia de colesterol n&#227;o HDL &#40;96<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41; para o ponto de corte &#40;144<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41; resultou em um escore z de 1&#44;85&#59; a &#225;rea desse ponto at&#233; desvios&#8208;padr&#227;o de 3&#44;0 &#224; direita cobre 3&#44;0&#37; dos valores acima do ponto de corte&#46; Por outro lado&#44; entre as meninas classificadas como obesas pelo PGC&#44; a diferen&#231;a matem&#225;tica da m&#233;dia de colesterol n&#227;o HDL &#40;118<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41; para o ponto de corte &#40;144<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41; resultou em um escore z de 1&#44;08&#59; e o restante da &#225;rea &#224; direita cobre 13&#44;8&#37; dos valores acima do ponto de corte&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">Considerando 40 o n&#250;mero de indiv&#237;duos em cada grupo&#44; 22<span class="elsevierStyleHsp" style=""></span>mg&#47;dL a diferen&#231;a m&#233;dia entre os grupos e 25<span class="elsevierStyleHsp" style=""></span>mg&#47;dL o desvio&#8208;padr&#227;o m&#233;dio nos valores de colesterol n&#227;o HDL&#44; o poder estat&#237;stico calculado <span class="elsevierStyleItalic">post&#8208;hoc</span> foi de 0&#44;98&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Discuss&#227;o</span><p id="par0105" class="elsevierStylePara elsevierViewall">O principal achado deste estudo foi que&#44; entre os meninos&#44; o IMC e a RCE foram semelhantes ao PGC&#44; ao passo que&#44; entre meninas&#44; o PGC foi superior ao IMC e RCE com rela&#231;&#227;o &#224; capacidade de detectar a associa&#231;&#227;o entre obesidade e o perfil lip&#237;dico desfavor&#225;vel&#46; Neste estudo&#44; o colesterol n&#227;o HDL foi preferencial sobre as outras fra&#231;&#245;es&#44; devido &#224; sua utilidade na predi&#231;&#227;o de fatores de risco cardiovascular&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> Al&#233;m disso&#44; o colesterol n&#227;o HDL mostra melhor associa&#231;&#227;o com medi&#231;&#245;es de gordura corporal<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">20</span></a> e adiposidade abdominal&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">21</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">A associa&#231;&#227;o entre excesso de adiposidade e perfil lip&#237;dico desfavor&#225;vel foi abordada por v&#225;rios estudos recentes&#46;<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">5&#8211;7&#44;22&#44;23</span></a> Reuter et al&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">7</span></a> estudaram de forma transversal 1&#46;234 crian&#231;as e adolescentes &#40;7&#8208;17 anos&#41; do Brasil e relataram que a dislipidemia foi mais prevalente nos meninos e meninas sedent&#225;rios e acima do peso&#47;obesos&#44; mesmo ap&#243;s ajuste para a idade&#46; Em um acompanhamento por dez anos de crian&#231;as e adolescentes chineses &#40;6&#8208;18 anos&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">5</span></a> foi observada uma tend&#234;ncia significativa de aumento na m&#233;dia de n&#237;veis s&#233;ricos de colesterol&#44; TG&#44; LDL&#8208;C e colesterol n&#227;o HDL e&#44; exceto para colesterol&#44; o perfil lip&#237;dico mostrou pioria em indiv&#237;duos obesos&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">No presente estudo&#44; al&#233;m dos valores m&#233;dios&#44; mostramos que a distribui&#231;&#227;o dos n&#237;veis de colesterol n&#227;o HDL foi afetada por obesidade&#44; embora em um grau diferente entre meninos&#44; depende do indicador de refer&#234;ncia&#46; Por outro lado&#44; entre meninas&#44; as obesas e n&#227;o obesas apresentaram curvas de distribui&#231;&#227;o dos n&#237;veis de colesterol n&#227;o HDL quase superpostas quando usados o IMC e a RCE&#44; ao passo que as obesas apresentaram maior mudan&#231;a para a direita na curva de distribui&#231;&#227;o dos n&#237;veis dos n&#237;veis de colesterol n&#227;o HDL quando usado o PGC&#46; Essa diferen&#231;a de sexo pode acontecer devido ao fato de&#44; entre as meninas&#44; a curva de colesterol n&#227;o HDL ter uma cauda mais curta para a direita &#40;ou seja&#44; menores valores de colesterol n&#227;o HDL &#224; direita da m&#233;dia&#41;&#46; Assim&#44; a propor&#231;&#227;o de meninas obesas com altos n&#237;veis de colesterol n&#227;o HDL identificadas pelo PGC foi duas vezes maior em compara&#231;&#227;o com o IMC e quatro vezes maior em compara&#231;&#227;o com a RCE&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">O melhor desempenho da BIA pode ser explicado por sua maior capacidade de discriminar entre gordura e massa magra&#44; ao passo que o IMC e a RCE usam vari&#225;veis antropom&#233;tricas n&#227;o espec&#237;ficas&#44; como peso&#44; estatura e circunfer&#234;ncia&#46; Al&#233;m disso&#44; a BIA foi feita com um dispositivo tetrapolar com eletrodos t&#225;teis&#44; que permite maior precis&#227;o na medi&#231;&#227;o de gordura corporal&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">24</span></a></p><p id="par0125" class="elsevierStylePara elsevierViewall">Um estudo recente que envolveu uma grande amostra de crian&#231;as e adolescentes &#40;n &#61; 1&#46;134&#41; do Brasil mostrou que os indicadores IMC&#44; RCE e espessura da dobra dermocut&#226;nea apresentaram baixo poder discriminat&#243;rio para prever dislipidemia&#44;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">25</span></a> apesar de um indicador espec&#237;fico de adiposidade&#44; como percentual de gordura corporal&#44; n&#227;o ter sido testado&#46; Ademais&#44; como a estat&#237;stica <span class="elsevierStyleItalic">c</span> &#40;&#225;rea sob a curva ROC&#41; tem como base apenas classifica&#231;&#245;es&#44; seu uso pode subestimar a probabilidade preditiva real em modelos de predi&#231;&#227;o de risco cl&#237;nico&#46;<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">26</span></a></p><p id="par0130" class="elsevierStylePara elsevierViewall">A obesidade na inf&#226;ncia &#233; amplamente associada a v&#225;rios fatores de risco cardiovascular&#44; como hipertens&#227;o&#44; resist&#234;ncia &#224; insulina e dislipidemia&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">8</span></a> O fraco perfil lip&#237;dico encontrado em grande parte das crian&#231;as obesas pode ser parcialmente explicado por resist&#234;ncia &#224; insulina relacionada &#224; obesidade&#46; Estudos mostraram que a insulina &#233; um poss&#237;vel inibidor de lipase sens&#237;vel a horm&#244;nios &#40;LSH&#41;&#59; enzima respons&#225;vel pela lipose no tecido adiposo&#46;<a class="elsevierStyleCrossRef" href="#bib0285"><span class="elsevierStyleSup">27</span></a> Assim&#44; na presen&#231;a de resist&#234;ncia &#224; insulina&#44; o aumento na atividade da LSH induz lipose e maior oferta de &#225;cidos graxos livres para circula&#231;&#227;o&#46; Esse mecanismo aumenta a produ&#231;&#227;o de TG no f&#237;gado<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">28</span></a> que gera aumento de LDL&#8208;C e redu&#231;&#227;o de HDL&#8208;C no plasma&#46;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">29</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">Este estudo mostra limita&#231;&#245;es e pontos fortes&#46; N&#227;o usamos uma amostra aleat&#243;ria da popula&#231;&#227;o de crian&#231;as e adolescentes de faixa et&#225;ria semelhante&#46; Portanto&#44; h&#225; uma limita&#231;&#227;o na extrapola&#231;&#227;o dos resultados para a popula&#231;&#227;o geral&#46; Contudo&#44; a diferen&#231;a em todos os indicadores n&#227;o deve ser prejudicada por vi&#233;s de sele&#231;&#227;o&#46; N&#227;o fizemos uma valida&#231;&#227;o interna da BIA para estabelecer sua capacidade de avaliar a gordura corporal na popula&#231;&#227;o estudada&#46; Contudo&#44; a valida&#231;&#227;o de imped&#226;ncia bioel&#233;trica multifrequ&#234;ncia com eletrodos t&#225;teis de oito pontos com rela&#231;&#227;o &#224; Dexa foi estabelecida para crian&#231;as e adolescentes&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">30</span></a> Uma grande amostra de crian&#231;as e adolescentes que possibilitou uma ampla avalia&#231;&#227;o da distribui&#231;&#227;o de colesterol foi o principal ponto forte&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">Nossos achados demonstraram que o percentual de gordura corporal avaliado por BIA foi superior aos indicadores de situa&#231;&#227;o do peso&#44; IMC e RCE para identificar crian&#231;as e adolescentes com perfil lip&#237;dico desfavor&#225;vel&#44; principalmente entre meninas&#46; Esse resultado incentiva o uso de percentual de gordura corporal em vez de indicadores de situa&#231;&#227;o do peso em estudos futuros de associa&#231;&#227;o entre obesidade e dist&#250;rbios metab&#243;licos em popula&#231;&#245;es pedi&#225;tricas&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Financiamento</span><p id="par0145" class="elsevierStylePara elsevierViewall">Funda&#231;&#227;o de Amparo &#224; Pesquisa do Estado do Esp&#237;rito Santo &#40;Fapes&#41;&#47;Programa de Pesquisa para o Sistema &#218;nico de Sa&#250;de &#40;Ppsus&#41; &#40;n&#176; 65854420&#47;2014&#41; e Funda&#231;&#227;o Vale&#46;</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Conflitos de interesse</span><p id="par0150" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
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        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To assess whether the indicators of weight status body mass index and waist&#8208;to&#8208;height ratio are similar to body fat percentage to identify obese children and adolescents with unfavorable lipid profile&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">This was a cross&#8208;sectional study involving 840 children and adolescents &#40;6&#8211;18 years&#41;&#46; The same individuals were classified as non&#8208;obese &#40;<span class="elsevierStyleSup">95</span>&#41; or obese &#40;&#8805;P<span class="elsevierStyleSup">95</span>&#41; according to body fat percentage and indicators of weight status&#44; body mass index&#44; and waist&#8208;to&#8208;height ratio&#46; Body fat percentage was obtained by multi&#8208;frequency bioelectrical impedance&#46; Linear association between obesity and increased lipid fractions was tested by ANCOVA&#46; Normal distribution curves of non&#8208;HDL cholesterol were designed for obese and non&#8208;obese&#46; To provide the proportion of obese individuals with elevated non&#8208;HDL&#8208;c across all indicators&#44; <span class="elsevierStyleItalic">Z</span>&#8208;score was calculated&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Obese boys presented higher non&#8208;HDL cholesterol when compared with those non&#8208;obese&#44; classified by body mass index &#40;107<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>28 <span class="elsevierStyleItalic">vs</span>&#46; 94<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>25<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#44; waist&#8208;to&#8208;height ratio &#40;115<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>29 <span class="elsevierStyleItalic">vs</span>&#46; 94<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>25<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41; and body fat percentage &#40;119<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>33 <span class="elsevierStyleItalic">vs</span>&#46; 94<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>24<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46; Differently&#44; obese girls presented with higher non&#8208;HDL cholesterol when compared with those non&#8208;obese only according to the body fat percentage classification &#40;118<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>24 <span class="elsevierStyleItalic">vs</span>&#46; 96<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>26<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46; A large shift to the right in the distribution curve of non&#8208;HDL cholesterol among obese girls compared with non&#8208;obese was observed only when body fat percentage was used to discriminate between obese and non&#8208;obese&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Body fat percentage was better than the indicators of weight status to identify children and adolescents with unfavorable lipid profile&#44; mainly among girls&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Investigar se os indicadores da condi&#231;&#227;o do peso&#44; &#237;ndice de massa corporal e raz&#227;o cintura&#47;estatura s&#227;o semelhantes ao percentual de gordura corporal para identifica&#231;&#227;o de crian&#231;as e adolescentes obesos com perfil lip&#237;dico desfavor&#225;vel&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudo transversal que envolveu 840 crian&#231;as e adolescentes &#40;6&#8208;18 anos&#41;&#46; Os mesmos indiv&#237;duos foram classificados em n&#227;o obesos &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>95&#41; ou obesos &#40;p<span class="elsevierStyleHsp" style=""></span>&#8805;<span class="elsevierStyleHsp" style=""></span>95&#41; de acordo com o percentual de gordura corporal e os indicadores da condi&#231;&#227;o do peso&#44; &#237;ndice de massa corporal e raz&#227;o cintura&#47;estatura&#46; O percentual de gordura corporal foi obtido por bioimped&#226;ncia multifrequencial tetrapolar&#46; A associa&#231;&#227;o linear entre obesidade e aumento das fra&#231;&#245;es lip&#237;dicas foi tesada por ANCOVA&#46; As curvas de distribui&#231;&#227;o normal de colesterol n&#227;o HDL foram constru&#237;das para obesos e n&#227;o obesos&#46; Para fornecer a propor&#231;&#227;o de indiv&#237;duos obesos com colesterol n&#227;o HDL elevado para todos os indicadores&#44; o escore z foi calculado&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Os meninos obesos apresentaram maior colesterol n&#227;o HDL em compara&#231;&#227;o com n&#227;o obesos de acordo com a classifica&#231;&#227;o fornecida pelo &#237;ndice de massa corporal &#40;107<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>28 em compara&#231;&#227;o com 94<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>25<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; raz&#227;o cintura&#47;estatura &#40;115<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>29 em compara&#231;&#227;o com 94<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>25<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e percentual de gordura corporal &#40;119<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>33 em compara&#231;&#227;o com 94<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>24<span class="elsevierStyleHsp" style=""></span>g&#47;dL&#44; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Diferentemente&#44; as meninas obesas apresentaram maior colesterol n&#227;o HDL em compara&#231;&#227;o com as n&#227;o obesas&#44; somente de acordo com a classifica&#231;&#227;o fornecida pelo percentual de gordura corporal &#40;118<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>24 em compara&#231;&#227;o com 96<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>26<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Um grande deslocamento para a direita na curva de distribui&#231;&#227;o de colesterol n&#227;o HDL entre meninas obesas em compara&#231;&#227;o com n&#227;o obesas foi observado somente quando o percentual de gordura corporal foi utilizado para discriminar obesas e n&#227;o obesas&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#227;o</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">O percentual de gordura corporal &#233; melhor do que os indicadores da condi&#231;&#227;o do peso na identifica&#231;&#227;o de crian&#231;as e adolescentes com perfil lip&#237;dico desfavor&#225;vel&#44; principalmente entre meninas&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Como citar este artigo&#58; Oliosa PR&#44; Zaniqueli D&#44; Alvim RO&#44; Barbosa MC&#44; Mill JG&#46; Body fat percentage is better than indicators of weight status to identify children and adolescents with unfavorable lipid profile&#46; J Pediatr &#40;Rio J&#41;&#46; 2019&#59;95&#58;112&#8211;8&#46;</p>"
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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Curvas de distribui&#231;&#227;o normal com valor de corte &#40;VC&#41; para colesterol n&#227;o HDL em meninos &#40;A&#44; B&#44; C&#41; e meninas &#40;D&#44; E&#44; F&#41; obesos e n&#227;o obesos de acordo com a classifica&#231;&#227;o fornecida pelo IMC&#44; RCE e PGC&#44; respectivamente&#46;</p> <p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">IMC&#44; &#237;ndice de massa corporal&#59; RCE&#44; raz&#227;o cintura&#47;estatura&#59; PGC&#44; percentual de gordura corporal&#46;</p>"
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          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">CC&#44; circunfer&#234;ncia da cintura&#59; FC&#44; frequ&#234;ncia card&#237;aca&#59; HDL&#8208;C&#44; colesterol de lipoprote&#237;na de alta densidade&#59; colesterol n&#227;o HDL&#44; colesterol total menos HDL&#8208;C&#59; IMC&#44; &#237;ndice de massa corporal&#59; LDL&#8208;C&#44; colesterol de lipoprote&#237;na de baixa densidade&#59; PAD&#44; press&#227;o arterial diast&#243;lica&#59; PAS&#44; press&#227;o arterial sist&#243;lica&#59; PGC&#44; percentual de gordura corporal&#59; RCE&#44; raz&#227;o cintura&#47;estatura&#59; TG&#44; triglicer&#237;deos&#46;</p><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Os dados s&#227;o expressos como m&#233;dia &#177; DP&#44; <span class="elsevierStyleItalic">p</span> &#60; 0&#44;05 para relev&#226;ncia estat&#237;stica&#46;</p>"
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                  <table border="0" frame="\n
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Todos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Masculino&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Valor de <span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">840&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">471&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">369&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Idade &#40;anos&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#44;3 &#177; 2&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#44;4 &#177; 2&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;642&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Estatura &#40;cm&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">150&#44;4 &#177; 16&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">148&#44;3 &#177; 14&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;049&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Peso &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44&#44;1 &#177; 15&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44&#44;1 &#177; 15&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44&#44;2 &#177; 14&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;957&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">IMC &#40;kg&#47;m<span class="elsevierStyleSup">2</span>&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;9 &#177; 3&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19&#44;5 &#177; 4&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;016&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">CC &#40;cm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">64&#44;7 &#177; 9&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">64&#44;9 &#177; 9&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">64&#44;4 &#177; 9&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;395&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">RCE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;43 &#177; 0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;43 &#177; 0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;43 &#177; 0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;525&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PGC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22&#44;8 &#177; 9&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">20&#44;1 &#177; 9&#44;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">26&#44;2 &#177; 8&#44;21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PAS &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">104 &#177; 9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">105 &#177; 10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">103 &#177; 8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PAD &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">62 &#177; 6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">62 &#177; 7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">63 &#177; 6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;027&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FC &#40;bpm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">74 &#177; 11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">71 &#177; 11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">77 &#177; 11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Colesterol total &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">143&#44;8 &#177; 27&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">143 &#177; 28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">145 &#177; 28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;285&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">LDL&#8208;C &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">78&#44;4 &#177; 24&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">78 &#177; 24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">79 &#177; 25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;431&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">HDL&#8208;C &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">47&#44;5 &#177; 9&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">47 &#177; 9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48 &#177; 10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;819&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Colesterol n&#227;o HDL &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">96 &#177; 26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">95 &#177; 25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">97 &#177; 26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;269&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TG &#40;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">69&#44;7 &#177; 29&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">68 &#177; 29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72 &#177; 30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;113&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "leyenda" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">HDL&#8208;C&#44; colesterol de lipoprote&#237;na de alta densidade&#59; colesterol n&#227;o HDL&#44; colesterol total menos HDL&#8208;C&#59; IMC&#44; &#237;ndice de massa corporal&#59; LDL&#8208;C&#44; colesterol de lipoprote&#237;na de baixa densidade&#59; PGC&#44; percentual de gordura corporal&#59; RCE&#44; raz&#227;o cintura&#47;estatura&#59; TG&#44; triglicer&#237;deos&#46;</p><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Os dados s&#227;o expressos como m&#233;dia &#177; DP&#44; <span class="elsevierStyleItalic">p</span> &#60; 0&#44;05 para relev&#226;ncia estat&#237;stica&#46;</p>"
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                0 => """
                  <table border="0" frame="\n
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">IMC</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">RCE</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">BFP</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Valor de <span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">P &#8805; 95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Valor de <span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#8805; P<span class="elsevierStyleSup">95th</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">410&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">434&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">437&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Idade &#40;anos&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#44;3 &#177; 2&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#44;6 &#177; 2&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;074&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#44;3 &#177; 2&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#44;4 &#177; 1&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;017&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#44;4 &#177; 2&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#44;7 &#177; 1&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;067&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">IMC &#40;kg&#47;m<span class="elsevierStyleSup">2</span>&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;0 &#177; 2&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">26&#44;5 &#177; 3&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;4 &#177; 3&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">26&#44;7 &#177; 3&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;6 &#177; 3&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">26&#44;3 &#177; 3&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">RCE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;42 &#177; 0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;54 &#177; 0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;42 &#177; 0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;52 &#177; 0&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;43 &#177; 0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;56 &#177; 0&#44;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PGC &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;1 &#177; 7&#44;2&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#44;9 &#177; 7&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">40&#44;0 &#177; 7&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19&#44;0 &#177; 7&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44&#44;6 &#177; 4&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">142 &#177; 27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">150 &#177; 30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;058&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">142 &#177; 27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">158 &#177; 30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">142 &#177; 27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">164 &#177; 35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">LDL&#8208;C &#40;mg&#47;dL&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">77 &#177; 24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">88 &#177; 28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">76 &#177; 24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">96 &#177; 29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">76 &#177; 23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">102 &#177; 32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">HDL&#8208;C &#40;mg&#47;dL&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">43 &#177; 10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48 &#177; 9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">43 &#177; 10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;022&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48 &#177; 9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">45 &#177; 9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;167&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Colesterol n&#227;o HDL &#40;mg&#47;dL&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">94 &#177; 25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">107 &#177; 28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">94 &#177; 25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">115 &#177; 29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">94 &#177; 24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">119 &#177; 33&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TG &#40;mg&#47;dL&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">65 &#177; 25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">96 &#177; 33&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">66 &#177; 22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">108 &#177; 39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">67 &#177; 27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">99 &#177; 46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">IMC</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">RCE</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">PGC</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">P &#60; 95&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">P &#8805; 95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Valor de <span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">P &#60; 95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">P &#8805; 95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Valor de <span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">334&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">334&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Idade &#40;anos&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#44;8 &#177; 2&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;217&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#44;8 &#177; 2&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;439&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#44;3 &#177; 2&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;061&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">27&#44;0 &#177; 4&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">145 &#177; 29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">150 &#177; 27&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">145 &#177; 29&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">144 &#177; 29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">160 &#177; 26&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">79 &#177; 25&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">78 &#177; 25&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">96 &#177; 26&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70 &#177; 29&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70 &#177; 29&nbsp;\t\t\t\t\t\t\n
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