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Letter to the Editor
Some flaws that could change the effect sizes and limit the extrapolation of these results
Alguns pontos fracos que podem alterar os tamanhos dos efeitos e limitar a extrapolação desses resultados
Carlos Alberto Velasco-Benítez
Corresponding author
, Herney Andrés García-Perdomo
Universidad del Valle, Cali, Colombia
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We have carefully read the article published by de Mello et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> and we have found several important issues to discuss&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Regarding the clinical topic&#44; inclusion of studies was based on Rome III Criteria&#59; however&#44; we found that authors misclassified four out of the nine articles included in this systematic review&#58; Castillejo et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> actually used functional constipation &#40;FC&#41; criteria according to Rome II&#59; Mozaffarpur et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> included patients classified using both Rome III criteria and the Paris Consensus on Childhood Constipation Terminology Criteria&#59; Loening-Baucke<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> defined FC according to the Medical Position Statement of the North American Society for Pediatric Gastroenterology and Nutrition in 1999&#59; finally&#44; Kokke et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> included patients according to Loening-Baucke&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> This unappropriated inclusion of studies might have led to different effect sizes due to clinical heterogeneity&#46; The authors should have stated that they were going to include different Rome Criteria and afterwards&#44; they should have conducted a sensibility or a subgroup analysis to identify the alteration in effect sizes&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Regarding the methods used to perform this systematic review&#44; we have found some flaws in the following issues<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a>&#58;<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">1&#46;</span><p id="par0020" class="elsevierStylePara elsevierViewall">Protocols for systematic reviews and meta-analysis must be published in PROSPERO before performing the entire process and the publication of the final manuscript&#46;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">2&#46;</span><p id="par0025" class="elsevierStylePara elsevierViewall">The search strategy must be based on patient &#40;population&#41;&#44; intervention&#44; and study design according to different manuscripts&#46; This one was based on patient&#44; outcome&#44; and study design&#44; which might lead to selection bias&#46;</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">3&#46;</span><p id="par0030" class="elsevierStylePara elsevierViewall">Using two tools for assessing bias is unnecessary &#40;RoB Cochrane tool and Jadad score&#41;&#46; If the authors wanted to perform another analysis&#44; assessing the quality of evidence using the GRADE tool would have been important and interesting&#46;</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">4&#46;</span><p id="par0035" class="elsevierStylePara elsevierViewall">There was no appropriate description of the strategy to identify non-published literature&#44; for example&#44; Google Scholar&#44; Open Grey database&#44; clinical trials registries&#44; and conferences&#44; among others&#46; This might have created publication bias&#46;</p></li></ul></p><p id="par0040" class="elsevierStylePara elsevierViewall">Consequently&#44; we suggest caution in the use of the findings when extrapolating results to clinical practice&#46;</p><span id="sec0021" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0041">Conflicts of interest</span><p id="par0105" class="elsevierStylePara elsevierViewall">The authors declare no conflicts of interest&#46;</p></span></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Velasco-Ben&#237;tez CA&#44; Garc&#237;a-Perdomo HA&#46; Some flaws that could change the effect sizes and limit the extrapolation of these results&#46; J Pediatr &#40;Rio J&#41;&#46; 2019&#59;95&#58;374&#8211;5&#46;</p>"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
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                            1 => "M&#46; Bullo"
                            2 => "A&#46; Anguera"
                            3 => "J&#46; Escribano"
                            4 => "F&#46;J&#46; Salas-Salvado"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
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                        "paginaFinal" => "e264"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14993586"
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                ]
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                          "etal" => false
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                            5 => "F&#46;J&#46; Tolboom"
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                        "link" => array:1 [
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                          "autores" => array:2 [
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Article information
ISSN: 00217557
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Jornal de Pediatria (English Edition)
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