Factors related to the association of social anxiety disorder and alcohol use among adolescents: a systematic review

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associação de transtorno de ansiedade social e uso de álcool entre adolescentes: uma revisão sistemática" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "fuente" => "Source: “Prisma: Transparent Reporting of Systematic Reviews and Meta-Analyses”." 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It is considered as a chronic pathology, capable of incapacitating the individual and promoting the development of high rates of psychiatric comorbidities, such as depression, generalized anxiety disorder, and agoraphobia, being the most common anxiety disorder and the third most frequent psychiatric disorder.<a class="elsevierStyleCrossRefs" href="#bib0155">1–4</a>These individuals have difficulties in interpersonal relationships (family and social interactions), low self-esteem, low school performance, school dropout, and impairment in memory, perception, and thinking processes. It is noteworthy that SAD usually precedes abuse and dependence of alcohol and other illicit substances, which aggravates symptoms.<a class="elsevierStyleCrossRef" href="#bib0175">5</a>Considered a public health problem, alcohol experimentation typically begins in adolescence, between the ages of 12 and 15 years, regardless of social context; individuals with early onset of SAD are at risk for developing depression or alcoholism.<a class="elsevierStyleCrossRefs" href="#bib0160">2,6,7</a> This diagnosis occurs shortly before or concurrently with the onset of substance use, which suggests an association between these two health problems and that, even in the face of this evidence, this type of disorder in adolescence has shown a conflicting association with the use of alcohol.The present systematic review aimed to identify the risk factors related to the association between SAD and alcohol use among adolescents.MethodA systematic review of the literature was carried out based on a search in the Medical Literature Analyses and Retrieval Online (Medline), Latin American and Caribbean Literature in Health Sciences (LILACS), PubMed, Indice Bibliográfico Español de Ciencias de la Salud (IBECS), and the Cochrane Library databases.For each research portal, a specific strategy was developed for crossing Descriptors in Health Sciences (DeCS, a Brazilian database of medical keywords) or Medical Subject Headings (MeSH). The keywords used for the study selection were: Phobic Disorders, Adolescents, Behavior, Ethanol, Risk Factors, and the corresponding terms in Portuguese. The Boolean operator “AND” was used to combine keywords and terms for searches. The selection was limited to studies published in Portuguese, English, or Spanish between 2010 and 2015.After the articles were identified, eligibility, selection, and exclusion criteria were applied. Original articles that had alcohol use as a risk factor for SADs were considered eligible. The Population, Intervention, Comparison, Outcome, Study Design (PICO) research strategy was used to construct the research question, in order to carry out the search for clinical evidence of the association between social phobia and alcohol use.<a class="elsevierStyleCrossRefs" href="#bib0190">8,9</a> The following were selected: cross-sectional, prospective/retrospective, and case–control studies, carried out in humans aged 10–19 years<a class="elsevierStyleCrossRef" href="#bib0200">10</a>; original studies; with alcoholism as a risk factor for phobic disorders. Studies that did not mention alcoholism and phobic disorders in the article title were excluded, as well as those with a population of young adults aged 20–24 years.Article selection was carried out in three steps, following the Transparent Reporting of Systematic Reviews and Meta-Analyses (PRISMA) method.<a class="elsevierStyleCrossRef" href="#bib0205">11</a> In the first step, two independent researchers read the titles without knowledge of the authors and the journal where they were published. After the exclusion of the repeated articles, the second step began, in which the abstracts of the selected studies were read and, likewise, those that did not meet the inclusion criteria were excluded. Disagreements were resolved by consensus. In the third step, all studies not excluded in the previous steps were read in full to select those that would be included in this review (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).<elsevierMultimedia ident="fig0005"></elsevierMultimedia>ResultsAfter exclusion of the repeated articles, 277 studies were eligible: 94 in MEDLINE, 68 in Pubmed, 12 in IBCS, and three in LILACS. The titles and abstracts were independently read by two examiners, totaling eight articles for analysis in this review.<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> shows the characteristics of the eight studies and the type of protocols used; one study was carried out in Finland and seven in the United States. A total of 4579 adolescents, aged 10–19 years, who had symptoms of SAD and who consumed alcohol were investigated. In 62.5% of the studies, the female gender predominated, accounting for 54% of the total sample.<elsevierMultimedia ident="tbl0005"></elsevierMultimedia>The association between social anxiety symptoms and alcohol use was confirmed in six studies, two of which were carried out in a group of adolescents with mean age between 10 and 11 years, whereas the others evaluated adolescents older than 15 years. The risk factors attributed by the studies for this association were female gender, peer acceptance, and affective problems for alcohol use, as well as the presence of secondary comorbidities, such as depression, generalized anxiety, agoraphobia, separation anxiety, and obsessive–compulsive disorder. Other factors such as cultural aspects, frequency of alcohol use, and frequency of intoxication investigated by the studies did not appear to be related to this association (<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>).<elsevierMultimedia ident="tbl0010"></elsevierMultimedia>DiscussionThe findings show that the evaluated association is still unclear, due to the small number of studies retrieved; however, 75% of the studies showed positive evidence between the association of SAD and alcohol use.Contextualization of study locationThis review identified a predominance of studies carried out in developed countries, primarily in the United States, which may be related to greater epidemiological surveillance in mental health for children and adolescents.It is important to remember that approximately one in five adolescents in that country suffer from a mental disorder severe enough to have an impact on their activities of daily living, and these are relevant data for the increase in the investigations.<a class="elsevierStyleCrossRef" href="#bib0210">12</a>In Brazil, population-based studies have shown that the onset of anxiety disorders occurs at the mean age of 13 years and the use of alcohol between 12 and 15 years, while substance abuse begins later, at the age of 24 years. This may be an indication that the resources available for the treatment of mental disorders in children and adolescents might be deficient, consequently increasing the rates of comorbidity in early adult life.<a class="elsevierStyleCrossRefs" href="#bib0215">13,14</a> This review did not retrieve any Brazilian publication that could clarify the national reality about the association between SAD and alcohol use.These data are important to emphasize the need to diagnose and follow-up adolescents who are predisposed to developing mental disorders and to initially establish preventive actions in schools and healthcare services, thus reducing the long-term associated burden on the individual, family, and community.SAD and alcohol useGiven that SAD is one of the most prevalent psychiatric conditions in the world's population, second only to depression,<a class="elsevierStyleCrossRef" href="#bib0180">6</a> and that its development precedes the onset of alcohol use disorders, it is important to carry out alcohol intervention activities,<a class="elsevierStyleCrossRef" href="#bib0225">15</a> as young individuals with SAD are five times more likely to develop alcohol dependence than those without the disorder.<a class="elsevierStyleCrossRefs" href="#bib0220">14,16–20</a>Studies that failed to show a significant association between SAD and alcohol use in adolescents,<a class="elsevierStyleCrossRefs" href="#bib0225">15,21</a> still indicated the possibility of reaching different results when cultural differences were observed, such as free access to alcohol by adolescents. Another observed risk was the development of this association with depression, which may occur in late adolescence or take more than two years to develop.It is worth emphasizing the importance of recognizing and treating anxiety disorders in childhood, especially among girls, aiming to help them prevent the development of substance use disorders and secondary comorbidities.<a class="elsevierStyleCrossRef" href="#bib0260">22</a>According to the Differential Diagnostic Guidelines for Social Anxiety Disorder, the age of SAD onset tends to occur earlier and the distribution between the genders is more homogeneous.<a class="elsevierStyleCrossRef" href="#bib0165">3</a> When analyzing gender in association with alcohol consumption among Brazilian adolescents in the National School Health Survey (PeNSE 2012), a higher prevalence of the female gender (51.7%; 95%CI: 50.8–52.6) was observed.<a class="elsevierStyleCrossRef" href="#bib0265">23</a> When assessing the influence of gender on the association between illicit substance use and social anxiety, it was observed that women with higher levels of social anxiety had a higher number of friends who use drugs and alcohol.<a class="elsevierStyleCrossRef" href="#bib0270">24</a>However, there are differences between the patterns observed in adolescents and the results of studies with adults, i.e., the association between anxiety disorders and substance use can change from adolescence to adulthood.<a class="elsevierStyleCrossRef" href="#bib0260">22</a> What is initially used as an anxiety coping tool, attenuating inhibition and making them feel safe while alleviating the fear in social situations throughout life, can lead to embarrassing situations and dependence, as well as the persistence of phobic symptoms.<a class="elsevierStyleCrossRef" href="#bib0275">25</a>In the study carried out at schools, libraries, and adolescent clubs in the Washington, DC, United States metropolitan area, the rates of alcohol use were relatively low; however, the results indicated that young individuals were more likely to have problems with alcohol consumption over time.<a class="elsevierStyleCrossRef" href="#bib0280">26</a>In the study that investigated social anxiety, generalized anxiety, and substance use (cigarettes and alcohol) in the early adolescence phase, it was observed that for the female gender, social anxiety is a risk factor when alcohol use approval use by peers is high (high levels of peer approval and high levels of social anxiety were associated with a high likelihood of substance use), whereas for generalized anxiety, it is considered a risk factor when the use by peers is low.<a class="elsevierStyleCrossRef" href="#bib0285">27</a>However, gender was not significantly associated with social anxiety and alcohol use, emphasizing age, frequency of alcohol use, and affective problems.<a class="elsevierStyleCrossRef" href="#bib0290">28</a> Nevertheless, this association was associated with affective problems, as well as reasons for survival and coping, so that young individuals who had elevated symptoms of the disorder reported increased motivation to drink associated with coping purposes. This was also demonstrated in the three models used to assess the groups of people with social anxiety who used alcohol in situations of confrontation and/or compliance reasons.<a class="elsevierStyleCrossRef" href="#bib0295">29</a>Adolescents with elevated social anxiety symptoms consume less alcohol, but show a higher association when it is related with coping endorsement and compliance motives.<a class="elsevierStyleCrossRef" href="#bib0300">30</a>Future perspectivesThe limitations of the analyzed studies are based on sample size; on the short period of follow-up of the adolescents; on the fact that, as it was not possible to observe the students’ behavior during the transition period from elementary to high school,<a class="elsevierStyleCrossRefs" href="#bib0225">15,26,28</a> the results cannot be generalized for all phases of adolescence or for all regions (rural and urban areas), since each phase has different characteristics and behaviors regarding the decision-making for use of alcohol according to the place of residence<a class="elsevierStyleCrossRef" href="#bib0285">27</a>; and on the use of a combination of variables regarding the use of alcohol, cigarettes, marijuana, and other substances, which has implications for their association with anxiety, as each substance has unique properties and distinct physiological effects.<a class="elsevierStyleCrossRefs" href="#bib0255">21,22,27</a>Regarding future investigations, it is necessary to assess the individuals at the initial, middle, and late adolescence phases, as well as to expand racial and ethnic groups; to use both the descriptive analysis (perceptions of the drinking behavior) and the analysis of precautionary norms (approval/disapproval of the drinking behavior); to evaluate the treatment and its effects on the adolescent; and to assess the coping reasons for drinking and problematic use of alcohol, with the ultimate goal of developing prevention programs aimed at young individuals at risk.LimitationsThe present systematic review study had as limitations: (a) non-use of the Web of Science and Pschynfo scientific databases, with the latter being the database specialized in behavioral and social science research; (b) scarcity of studies published in Portuguese, English, or Spanish; and (c) the small number of articles included in the analysis.Despite the limitations, this review becomes relevant, as it allowed the identification and understanding of the main risk factors associated with SAD and alcohol use in adolescents, in addition to broadening the knowledge about the subject.ConclusionsThe association between SAD and alcohol use in adolescents appears to be unclear, due to the few identified studies, the methodological heterogeneity, and their regionalization. Nevertheless, this review raised interesting evidence on the existence of this association and identified the main risk factors related to the association between SAD and alcohol use among adolescents, such as female gender, peer acceptance, and affective problems regarding alcohol use, as well as the presence of secondary comorbidities, such as depression and anxiety disorders. Therefore, studies with representative samples, with an increase in the racial and ethnic groups and that contemplate the initial, middle, and late phases of adolescence are still necessary.Some authors also suggest that prospective studies be carried out to observe students’ behavior during the transition period from elementary to high school, as well as evaluate the onset period of the first symptoms of SAD and the risks for alcohol use; assess the reasons for alcohol use; evaluate treatment and its effects on adolescents; and to implement corrective intervention guidelines for alcohol use among socially anxious students.Conflicts of interestThe authors declare no conflicts of interest." "textoCompletoSecciones" => array:1 [ "secciones" => array:11 [ 0 => array:3 [ "identificador" => "xres904113" "titulo" => "Abstract" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Objective" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Source of data" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Synthesis of data" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Conclusions" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec884732" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres904114" "titulo" => "Resumo" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abst0025" "titulo" => "Objetivo" ] 1 => array:2 [ "identificador" => "abst0030" "titulo" => "Fontes dos dados" ] 2 => array:2 [ "identificador" => "abst0035" "titulo" => "Síntese dos dados" ] 3 => array:2 [ "identificador" => "abst0040" "titulo" => "Conclusões" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec884731" "titulo" => "Palavras-chave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Method" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Results" ] 7 => array:3 [ "identificador" => "sec0020" "titulo" => "Discussion" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0025" "titulo" => "Contextualization of study location" ] 1 => array:2 [ "identificador" => "sec0030" "titulo" => "SAD and alcohol use" ] 2 => array:2 [ "identificador" => "sec0035" "titulo" => "Future perspectives" ] 3 => array:2 [ "identificador" => "sec0040" "titulo" => "Limitations" ] ] ] 8 => array:2 [ "identificador" => "sec0045" "titulo" => "Conclusions" ] 9 => array:2 [ "identificador" => "sec0050" "titulo" => "Conflicts of interest" ] 10 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2016-10-20" "fechaAceptado" => "2017-01-09" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec884732" "palabras" => array:5 [ 0 => "Phobic disorders" 1 => "Adolescent" 2 => "Behavior" 3 => "Ethanol" 4 => "Risk factors" ] ] ] "pt" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palavras-chave" "identificador" => "xpalclavsec884731" "palabras" => array:5 [ 0 => "Transtornos fóbicos" 1 => "Adolescente" 2 => "Comportamento" 3 => "Etanol" 4 => "Fatores de risco" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:3 [ "titulo" => "Abstract" "resumen" => "ObjectiveTo identify the risk factors related to the association between social anxiety disorder and alcohol use in adolescents. Source of dataThe PICO research strategy was used to perform a systematic review in Medline, LILACS, Pubmed, IBECS and Cochrane Library databases. DeCS/MeSH: Phobic Disorders, Adolescent, Behavior, Ethanol, Risk Factors, and the Boolean operator “AND” were used. Inclusion criteria were: cross-sectional, prospective/retrospective cohort, and case-control studies, carried out in adolescents (10–19 years), original articles on social anxiety disorder and alcohol use published between 2010 and 2015. Studies that did not report the terms “anxiety disorder” and “alcohol use” in the title and abstract were excluded. Synthesis of data409 articles were retrieved; after the exclusion of 277 repeated articles, the following were eligible: 94 in MEDLINE, 68 in Pubmed, 12 in IBCS, and three in LILACS. Titles and abstracts were independently read by two examiners, which resulted in the selection of eight articles for the analysis. Risk factors associated to the two disorders were female gender, age, peer approval and affective problems for alcohol use, confrontation situations and/or compliance reasons, frequency of alcohol use, and secondary comorbidities, such as depression and generalized anxiety. ConclusionsIt is necessary to assess the period of social anxiety disorders first symptom onset, as well as the risks for alcohol use in order to establish corrective intervention guidelines, especially for socially anxious students." "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Objective" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Source of data" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Synthesis of data" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Conclusions" ] ] ] "pt" => array:3 [ "titulo" => "Resumo" "resumen" => "ObjetivoIdentificar os fatores de risco relacionados a associação entre o transtorno de ansiedade social e uso de álcool entre adolescentes. Fontes dos dadosUtilizou-se a estratégia de pesquisa PICO para realizar a revisão sistemática nas bases Medline, LILACS, Pubmed, IBECS e Biblioteca Cochrane. Foi utilizado os DeCS/MeSH: Transtornos Fóbicos, Adolescente, Comportamento, Etanol, Fatores de Risco e o operador boleano “AND”. Os critérios de inclusão foram: estudo transversal, coorte prospectiva/retrospectiva e caso-controle, realizados em adolescentes (10 a 19 anos), artigos originais sobre transtorno de ansiedade social e uso de álcool publicado entre 2010 a 2015. Excluíram-se os estudos que não referiam transtorno de ansiedade e uso de álcool no título e no resumo. Síntese dos dados409 artigos foram identificados e após exclusão repetidos 277 estudos foram elegíveis: 94 no MEDLINE, 68 em Pubmed, 12 IBCS e 3 LILACS. Foi realizada a leitura dos títulos e resumos de forma independente por dois examinadores, que resultou na seleção de 8 artigos para análise. Fatores de riscos associados aos dois transtornos: predominância do gênero feminino, idade, aprovações pelos pares e problemas afetivos para o uso de álcool, situações de enfrentamentos e/ou motivos de conformidades, frequência de uso do álcool e comorbidades secundárias como depressão e ansiedade generalizada. ConclusõesÉ necessário avaliar o período de surgimento dos primeiros sintomas de transtorno de ansiedade social e dos riscos para o uso de álcool e instituir normas corretivas de intervenções, principalmente para os alunos socialmente ansiosos." "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abst0025" "titulo" => "Objetivo" ] 1 => array:2 [ "identificador" => "abst0030" "titulo" => "Fontes dos dados" ] 2 => array:2 [ "identificador" => "abst0035" "titulo" => "Síntese dos dados" ] 3 => array:2 [ "identificador" => "abst0040" "titulo" => "Conclusões" ] ] ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Cruz EL, Martins PD, Diniz PR. Factors related to the association of social anxiety disorder and alcohol use among adolescents: a systematic review. J Pediatr (Rio J). 2017;93:442–51." ] ] "multimedia" => array:3 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "fuente" => "Source: “Prisma: Transparent Reporting of Systematic Reviews and Meta-Analyses”." "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2181 "Ancho" => 2252 "Tamanyo" => 238389 ] ] "descripcion" => array:1 [ "en" => "Flowchart representing the selection steps of articles about social anxiety disorder and alcohol abuse in adolescents." ] ] 1 => array:8 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at1" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Authors, year, and impact factor (IF) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Country \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Study duration and sample \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Gender and age \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Type of study \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Research tool \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Fröjd et al. (2011) IF: 1.09 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Finland \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">48 months Sample: 2070 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Boys: 903 Girls: 1167 Mean age: 17.6 (SD=0.41) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Longitudinal study \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Social Phobia Inventory (SPIN) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Terlecki et al. (2012) IF: 1.36 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">USA \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Sample: 52 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Boys: 35 Girls: 17 Mean age: 20.38 (SD=1.46) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Longitudinal study \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Alcohol Use Disorder Identification Test (AUDIT) Brief Alcohol Screening and Intervention for College Students (BASICS) Quantity/Frequency/Peak Index (QFI) Drinking Norms Rating Form (DNRF) Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS) Spielberger Trait Anxiety Inventory \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Dahne et al. (2014) IF: 1.41 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">USA \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">48 months Sample: 277 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Boys: 156 Girls: 121 Mean age de 11 (SD=0.81) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Longitudinal study \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Generalized estimating equations (GEE) The Revised Child Anxiety and Depression Scale (RCADS) Youth Risk Behavior Surveillance System \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Zehe et al. (2013) IF: 1.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">USA \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">12 months Sample: 387 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Boys: 174 Girls: 213 Mean age: 12.1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Longitudinal study \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Social Anxiety Scale For Children – Revised (SASC-R) Youth Self-Report Survey (YSR) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Terlecki and Buckner (2015) IF: 1.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">USA \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Sample: 232 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Boys: 71 Girls: 161 Mean age: 19.32 (SD=1.34) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Cross-sectional study \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Social Phobia Scale (SPS) Social Interaction Anxiety Scale (SIAS) Drinking Motives Questionnaire Revised (DMQR) Drinking Context Scale-Revised (DCS-R) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Blumenthal et al. (2010) IF: 1.36 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">USA \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Sample: 50 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Boys: 24 Girls: 26 Mean age 16.35 (SD=1.10) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Cross-sectional study \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Adolescent Alcohol and Drug Involvement Scale (AADIS) Youth Self Report (YSR) Drinking Motives Questionnaire Revised (DMQ-R) Revised Child Anxiety and Depression Scale – Social phobia subscale (RCADSSP) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Wu et al. (2010) IF: 1.47 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">USA  \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Sample: 781 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Boys: 412 Girls: 369 Mean age: 15 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Cross-sectional study \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Diagnostic Interview Schedule for Children (DISC)  \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Clerkin. Barnett (2012) IF: 1.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">USA \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">12 months Sample: 730 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Boys: 295 Girls: 435 Mean age 18.35 (SD=0.47) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Cross-sectional study \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Social Avoidance and Distress Scale (SADS) Drinking Motives Questionnaire – Revised The Graduated Frequency for Alcohol Questionnaire Young Adult Alcohol Problems Screening Test \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1520115.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Characteristics of the studies and types of protocols used." ] ] 2 => array:8 [ "identificador" => "tbl0010" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at2" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Authors, year and impact factor (IF) \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Objective \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Analyzed risk factors \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Results \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Conclusions \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Fröjd et al. (2011) IF: 1.09 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">To investigate whether the association between anxiety and alcohol and other substances are already evident in the middle adolescence, and whether the general anxiety or social phobia symptoms affects the continuity of frequent use of alcohol, frequent drunkenness, and marijuana use. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Generalized anxiety Social phobia Substance use Frequency of use Drunkenness frequency Use of marijuana \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Anxiety preceded the use of the substance, while no reciprocal associations were observed. Depression-mediated associations between anxiety and substance use. Symptoms of social phobia did not increase the incidence of substance use, but overall anxiety. General anxiety increased the persistence of frequent alcohol use, while co-morbid social phobia decreased its persistence. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">General anxiety in adolescence puts adolescents at risk for substance use. The risk may, however, be associated with depression. Social phobia in middle adolescence may protect against substance use. Adolescents with symptoms of internalization may need guidance in coping with symptoms, even though the symptoms did not meet the criteria of mood or anxiety disorder.  \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Terlecki et al. (2012) IF: 1.36 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">To evaluate whether socially anxious students showed less change in alcohol use behavior among college students.  \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Social anxiety Typical drinks Rules for drinking \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Among students with minor changes in rules, being a member of a group with social anxiety was associated with heavier drinking of typical drinks. Among students with major changes in rules, being a member of a social anxiety group was not significant. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Generalized anxiety in middle adolescence puts adolescents at risk for concomitant substance use and subsequently in late adolescence. The risk may, however, be associated with depression. Social anxiety and use of alcohol or substance was not observed in middle and late adolescence. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Dahne et al. (2014) IF: 1.41 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">To assess whether social phobia symptoms predicted increased likelihood of alcohol use over time. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Demographic data Psychopathology Alcohol use \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">There were correlations between the baseline predictors (child's age, child's gender, baseline alcohol use, social phobia symptoms) and waves 1–5 alcohol use In general, the concurrent associations were low to moderate. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">It highlights the importance of social phobia symptoms in predicting alcohol use over time among young adolescents. Several future directions within this line of research would be valuable, including expanding the assessed age range to younger children and adolescents/older young adults. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Zehe et al. (2013) IF: 1.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">To assess the association between social and generalized anxiety symptoms and alcohol and cigarette use in early adolescence and as a precautionary measure (perceived peer use approval) and (perceived use point) descriptive rules may moderate the association. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Peer norms Gender differences \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Peer norms were moderated for the association between social anxiety symptoms, generalized anxiety, and the likelihood of alcohol and cigarette use by girls, but not for boys. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Girls with high levels of social anxiety symptoms were at risk for use when perceived peer approval of use was high, and protected from use when perceived peer approval of use was low. Profiles of anxiety symptoms and perceived peer approval of use may help identify girls who are potential targets for intervention, but the nature of these interventions is still unclear, since this study did not assess the potential risk mechanisms. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Terlecki and Buckner (2015) IF: 1.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Identify cognitive/motivational factors related to drinking in high-risk situations. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Demographic data Social anxiety and Reasons to drink \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">High social anxiety was associated with greater coping and compliance reasons. Both coping and compliance motives were mediated, the association between social anxiety to heavy alcohol consumption to negative emotional and personal/intimate contexts. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Multiple mediation analysis has indicated that to mediate anxiety situations university students drink socially, such that heavy drinking among college students with clinically elevated social anxiety can be attributed jointly to the desire to deal with negative affect and to avoid social scrutiny.  \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Blumenthal et al. (2010) IF: 1.36 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">To assess the reasons for alcohol use among young individuals as a function of social anxiety, associated variables (age, gender, frequency of alcohol use, affective problems) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Age Frequency of alcohol use Affective problems \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">High social anxiety was significantly associated with a high level of affective problems, as well as with coping reasons. Social anxiety was significantly associated with coping motives, so that young individuals who had high social anxiety reported greater motivation to drink for coping-related purposes. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Socially anxious young individuals endorse higher consumption motives, related to coping issues, a characteristic that may put them at risk for developing alcoholism problems. Prospective studies focused on clarifying associations between adolescent social anxiety, dealing with reasons for drinking and problematic use of alcohol, with the ultimate goal of designing prevention programs targeting young individuals at risk for social anxiety. \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Wu et al. (2010) IF: 1.47 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">To assess the use of three substance categories by adolescents (frequent smoking, frequent drinking/heavy use, and use of illicit drugs) in relation to each of the six anxiety disorders (social phobia, agoraphobia, high anxiety disorder/generalized anxiety disorder, separation anxiety, and obsessive-compulsive disorder). \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Substance use Anxiety disorder Demographics and family factors Depression \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Social phobia was associated with smoking only among boys. For girls, social phobia appeared to be negatively associated with drug use. For the other anxiety disorders, associations with substance use tend to be stronger among girls. There was an association between social anxiety symptoms and alcohol use only in girls. Frequent or heavy drinking was more common among boys than girls, but this difference was only marginally significant. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">The differences between the patterns observed in the study sample of adolescents and the results of studies with adults regarding social phobia to some extent indicate that the association between anxiety disorders and substance use may change from adolescence to adulthood.  \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Clerkin and Barnett (2012) IF: 1.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">To test the separate and interactive effects of drinking motives and social anxiety symptoms in predicting drinking and drinking-related problems. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Social anxiety symptoms Reasons to drink Alcohol consumption Problems with alcohol \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Increased social anxiety symptoms were significantly associated with less alcohol consumption, and there was some evidence that greater social anxiety symptoms were also associated with greater problems with alcohol. \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">The main effects of social anxiety symptoms and consumption motives were more influential in predicting consumption outcomes. Greater social anxiety was associated with greater endorsement of coping and compliance motives, and less endorsement of reasons for enhancement. Symptoms of social anxiety were associated to lower alcohol consumption, and also with more problems with drinking. \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1520114.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Summary of studies and risk factors associated with social anxiety disorder and alcohol use in adolescents." ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:30 [ 0 => array:3 [ "identificador" => "bib0155" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Saúde mental na escola: o que os educadores devem saber" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.M. 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Fatores relacionados à associação de transtorno de ansiedade social e uso de álcool entre adolescentes: uma revisão sistemática

Elisabeth Lima Dias da Cruza,

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elisabeth.cruz@gmail.com

Corresponding author.

, Priscila Diniz de Carvalho Martinsb, Paula Rejane Beserra Diniza

a Universidade Federal de Pernambuco (UFPE), Pós-graduação em Neuropsiquiatria e Ciência do Comportamento, Recife, PE, Brazil

b Universidade Federal de Pernambuco (UFPE), Pós-graduação em Saúde da Criança e do Adolescente, Recife, PE, Brazil

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    "titulo" => "Factors related to the association of social anxiety disorder and alcohol use among adolescents&#58; a systematic review"
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          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Flowchart representing the selection steps of articles about social anxiety disorder and alcohol abuse in adolescents&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Social anxiety disorder &#40;SAD&#41; is a condition that starts in childhood&#47;adolescence and is characterized by excessive fear or intense anxiety when the individual is faced with social exposure situations in public or meeting new people&#46; It is estimated that between 5&#37; and 13&#37; of the population have this problem&#46; It is considered as a chronic pathology&#44; capable of incapacitating the individual and promoting the development of high rates of psychiatric comorbidities&#44; such as depression&#44; generalized anxiety disorder&#44; and agoraphobia&#44; being the most common anxiety disorder and the third most frequent psychiatric disorder&#46;<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">1&#8211;4</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">These individuals have difficulties in interpersonal relationships &#40;family and social interactions&#41;&#44; low self-esteem&#44; low school performance&#44; school dropout&#44; and impairment in memory&#44; perception&#44; and thinking processes&#46; It is noteworthy that SAD usually precedes abuse and dependence of alcohol and other illicit substances&#44; which aggravates symptoms&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">5</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Considered a public health problem&#44; alcohol experimentation typically begins in adolescence&#44; between the ages of 12 and 15 years&#44; regardless of social context&#59; individuals with early onset of SAD are at risk for developing depression or alcoholism&#46;<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">2&#44;6&#44;7</span></a> This diagnosis occurs shortly before or concurrently with the onset of substance use&#44; which suggests an association between these two health problems and that&#44; even in the face of this evidence&#44; this type of disorder in adolescence has shown a conflicting association with the use of alcohol&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The present systematic review aimed to identify the risk factors related to the association between SAD and alcohol use among adolescents&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Method</span><p id="par0025" class="elsevierStylePara elsevierViewall">A systematic review of the literature was carried out based on a search in the Medical Literature Analyses and Retrieval Online &#40;Medline&#41;&#44; Latin American and Caribbean Literature in Health Sciences &#40;LILACS&#41;&#44; PubMed&#44; Indice Bibliogr&#225;fico Espa&#241;ol de Ciencias de la Salud &#40;IBECS&#41;&#44; and the Cochrane Library databases&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">For each research portal&#44; a specific strategy was developed for crossing Descriptors in Health Sciences &#40;DeCS&#44; a Brazilian database of medical keywords&#41; or Medical Subject Headings &#40;MeSH&#41;&#46; The keywords used for the study selection were&#58; Phobic Disorders&#44; Adolescents&#44; Behavior&#44; Ethanol&#44; Risk Factors&#44; and the corresponding terms in Portuguese&#46; The Boolean operator &#8220;AND&#8221; was used to combine keywords and terms for searches&#46; The selection was limited to studies published in Portuguese&#44; English&#44; or Spanish between 2010 and 2015&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">After the articles were identified&#44; eligibility&#44; selection&#44; and exclusion criteria were applied&#46; Original articles that had alcohol use as a risk factor for SADs were considered eligible&#46; The Population&#44; Intervention&#44; Comparison&#44; Outcome&#44; Study Design &#40;PICO&#41; research strategy was used to construct the research question&#44; in order to carry out the search for clinical evidence of the association between social phobia and alcohol use&#46;<a class="elsevierStyleCrossRefs" href="#bib0190"><span class="elsevierStyleSup">8&#44;9</span></a> The following were selected&#58; cross-sectional&#44; prospective&#47;retrospective&#44; and case&#8211;control studies&#44; carried out in humans aged 10&#8211;19 years<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">10</span></a>&#59; original studies&#59; with alcoholism as a risk factor for phobic disorders&#46; Studies that did not mention alcoholism and phobic disorders in the article title were excluded&#44; as well as those with a population of young adults aged 20&#8211;24 years&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Article selection was carried out in three steps&#44; following the Transparent Reporting of Systematic Reviews and Meta-Analyses &#40;PRISMA&#41; method&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">11</span></a> In the first step&#44; two independent researchers read the titles without knowledge of the authors and the journal where they were published&#46; After the exclusion of the repeated articles&#44; the second step began&#44; in which the abstracts of the selected studies were read and&#44; likewise&#44; those that did not meet the inclusion criteria were excluded&#46; Disagreements were resolved by consensus&#46; In the third step&#44; all studies not excluded in the previous steps were read in full to select those that would be included in this review &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0045" class="elsevierStylePara elsevierViewall">After exclusion of the repeated articles&#44; 277 studies were eligible&#58; 94 in MEDLINE&#44; 68 in Pubmed&#44; 12 in IBCS&#44; and three in LILACS&#46; The titles and abstracts were independently read by two examiners&#44; totaling eight articles for analysis in this review&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> shows the characteristics of the eight studies and the type of protocols used&#59; one study was carried out in Finland and seven in the United States&#46; A total of 4579 adolescents&#44; aged 10&#8211;19 years&#44; who had symptoms of SAD and who consumed alcohol were investigated&#46; In 62&#46;5&#37; of the studies&#44; the female gender predominated&#44; accounting for 54&#37; of the total sample&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">The association between social anxiety symptoms and alcohol use was confirmed in six studies&#44; two of which were carried out in a group of adolescents with mean age between 10 and 11 years&#44; whereas the others evaluated adolescents older than 15 years&#46; The risk factors attributed by the studies for this association were female gender&#44; peer acceptance&#44; and affective problems for alcohol use&#44; as well as the presence of secondary comorbidities&#44; such as depression&#44; generalized anxiety&#44; agoraphobia&#44; separation anxiety&#44; and obsessive&#8211;compulsive disorder&#46; Other factors such as cultural aspects&#44; frequency of alcohol use&#44; and frequency of intoxication investigated by the studies did not appear to be related to this association &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0060" class="elsevierStylePara elsevierViewall">The findings show that the evaluated association is still unclear&#44; due to the small number of studies retrieved&#59; however&#44; 75&#37; of the studies showed positive evidence between the association of SAD and alcohol use&#46;</p><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Contextualization of study location</span><p id="par0065" class="elsevierStylePara elsevierViewall">This review identified a predominance of studies carried out in developed countries&#44; primarily in the United States&#44; which may be related to greater epidemiological surveillance in mental health for children and adolescents&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">It is important to remember that approximately one in five adolescents in that country suffer from a mental disorder severe enough to have an impact on their activities of daily living&#44; and these are relevant data for the increase in the investigations&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">12</span></a></p><p id="par0075" class="elsevierStylePara elsevierViewall">In Brazil&#44; population-based studies have shown that the onset of anxiety disorders occurs at the mean age of 13 years and the use of alcohol between 12 and 15 years&#44; while substance abuse begins later&#44; at the age of 24 years&#46; This may be an indication that the resources available for the treatment of mental disorders in children and adolescents might be deficient&#44; consequently increasing the rates of comorbidity in early adult life&#46;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">13&#44;14</span></a> This review did not retrieve any Brazilian publication that could clarify the national reality about the association between SAD and alcohol use&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">These data are important to emphasize the need to diagnose and follow-up adolescents who are predisposed to developing mental disorders and to initially establish preventive actions in schools and healthcare services&#44; thus reducing the long-term associated burden on the individual&#44; family&#44; and community&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">SAD and alcohol use</span><p id="par0085" class="elsevierStylePara elsevierViewall">Given that SAD is one of the most prevalent psychiatric conditions in the world&#39;s population&#44; second only to depression&#44;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">6</span></a> and that its development precedes the onset of alcohol use disorders&#44; it is important to carry out alcohol intervention activities&#44;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a> as young individuals with SAD are five times more likely to develop alcohol dependence than those without the disorder&#46;<a class="elsevierStyleCrossRefs" href="#bib0220"><span class="elsevierStyleSup">14&#44;16&#8211;20</span></a></p><p id="par0090" class="elsevierStylePara elsevierViewall">Studies that failed to show a significant association between SAD and alcohol use in adolescents&#44;<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">15&#44;21</span></a> still indicated the possibility of reaching different results when cultural differences were observed&#44; such as free access to alcohol by adolescents&#46; Another observed risk was the development of this association with depression&#44; which may occur in late adolescence or take more than two years to develop&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">It is worth emphasizing the importance of recognizing and treating anxiety disorders in childhood&#44; especially among girls&#44; aiming to help them prevent the development of substance use disorders and secondary comorbidities&#46;<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">22</span></a></p><p id="par0100" class="elsevierStylePara elsevierViewall">According to the Differential Diagnostic Guidelines for Social Anxiety Disorder&#44; the age of SAD onset tends to occur earlier and the distribution between the genders is more homogeneous&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">3</span></a> When analyzing gender in association with alcohol consumption among Brazilian adolescents in the National School Health Survey &#40;PeNSE 2012&#41;&#44; a higher prevalence of the female gender &#40;51&#46;7&#37;&#59; 95&#37;CI&#58; 50&#46;8&#8211;52&#46;6&#41; was observed&#46;<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">23</span></a> When assessing the influence of gender on the association between illicit substance use and social anxiety&#44; it was observed that women with higher levels of social anxiety had a higher number of friends who use drugs and alcohol&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">24</span></a></p><p id="par0105" class="elsevierStylePara elsevierViewall">However&#44; there are differences between the patterns observed in adolescents and the results of studies with adults&#44; <span class="elsevierStyleItalic">i&#46;e&#46;</span>&#44; the association between anxiety disorders and substance use can change from adolescence to adulthood&#46;<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">22</span></a> What is initially used as an anxiety coping tool&#44; attenuating inhibition and making them feel safe while alleviating the fear in social situations throughout life&#44; can lead to embarrassing situations and dependence&#44; as well as the persistence of phobic symptoms&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">25</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">In the study carried out at schools&#44; libraries&#44; and adolescent clubs in the Washington&#44; DC&#44; United States metropolitan area&#44; the rates of alcohol use were relatively low&#59; however&#44; the results indicated that young individuals were more likely to have problems with alcohol consumption over time&#46;<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">26</span></a></p><p id="par0115" class="elsevierStylePara elsevierViewall">In the study that investigated social anxiety&#44; generalized anxiety&#44; and substance use &#40;cigarettes and alcohol&#41; in the early adolescence phase&#44; it was observed that for the female gender&#44; social anxiety is a risk factor when alcohol use approval use by peers is high &#40;high levels of peer approval and high levels of social anxiety were associated with a high likelihood of substance use&#41;&#44; whereas for generalized anxiety&#44; it is considered a risk factor when the use by peers is low&#46;<a class="elsevierStyleCrossRef" href="#bib0285"><span class="elsevierStyleSup">27</span></a></p><p id="par0120" class="elsevierStylePara elsevierViewall">However&#44; gender was not significantly associated with social anxiety and alcohol use&#44; emphasizing age&#44; frequency of alcohol use&#44; and affective problems&#46;<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">28</span></a> Nevertheless&#44; this association was associated with affective problems&#44; as well as reasons for survival and coping&#44; so that young individuals who had elevated symptoms of the disorder reported increased motivation to drink associated with coping purposes&#46; This was also demonstrated in the three models used to assess the groups of people with social anxiety who used alcohol in situations of confrontation and&#47;or compliance reasons&#46;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">29</span></a></p><p id="par0125" class="elsevierStylePara elsevierViewall">Adolescents with elevated social anxiety symptoms consume less alcohol&#44; but show a higher association when it is related with coping endorsement and compliance motives&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">30</span></a></p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Future perspectives</span><p id="par0130" class="elsevierStylePara elsevierViewall">The limitations of the analyzed studies are based on sample size&#59; on the short period of follow-up of the adolescents&#59; on the fact that&#44; as it was not possible to observe the students&#8217; behavior during the transition period from elementary to high school&#44;<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">15&#44;26&#44;28</span></a> the results cannot be generalized for all phases of adolescence or for all regions &#40;rural and urban areas&#41;&#44; since each phase has different characteristics and behaviors regarding the decision-making for use of alcohol according to the place of residence<a class="elsevierStyleCrossRef" href="#bib0285"><span class="elsevierStyleSup">27</span></a>&#59; and on the use of a combination of variables regarding the use of alcohol&#44; cigarettes&#44; marijuana&#44; and other substances&#44; which has implications for their association with anxiety&#44; as each substance has unique properties and distinct physiological effects&#46;<a class="elsevierStyleCrossRefs" href="#bib0255"><span class="elsevierStyleSup">21&#44;22&#44;27</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">Regarding future investigations&#44; it is necessary to assess the individuals at the initial&#44; middle&#44; and late adolescence phases&#44; as well as to expand racial and ethnic groups&#59; to use both the descriptive analysis &#40;perceptions of the drinking behavior&#41; and the analysis of precautionary norms &#40;approval&#47;disapproval of the drinking behavior&#41;&#59; to evaluate the treatment and its effects on the adolescent&#59; and to assess the coping reasons for drinking and problematic use of alcohol&#44; with the ultimate goal of developing prevention programs aimed at young individuals at risk&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Limitations</span><p id="par0140" class="elsevierStylePara elsevierViewall">The present systematic review study had as limitations&#58; &#40;a&#41; non-use of the Web of Science and Pschynfo scientific databases&#44; with the latter being the database specialized in behavioral and social science research&#59; &#40;b&#41; scarcity of studies published in Portuguese&#44; English&#44; or Spanish&#59; and &#40;c&#41; the small number of articles included in the analysis&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">Despite the limitations&#44; this review becomes relevant&#44; as it allowed the identification and understanding of the main risk factors associated with SAD and alcohol use in adolescents&#44; in addition to broadening the knowledge about the subject&#46;</p></span></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Conclusions</span><p id="par0150" class="elsevierStylePara elsevierViewall">The association between SAD and alcohol use in adolescents appears to be unclear&#44; due to the few identified studies&#44; the methodological heterogeneity&#44; and their regionalization&#46; Nevertheless&#44; this review raised interesting evidence on the existence of this association and identified the main risk factors related to the association between SAD and alcohol use among adolescents&#44; such as female gender&#44; peer acceptance&#44; and affective problems regarding alcohol use&#44; as well as the presence of secondary comorbidities&#44; such as depression and anxiety disorders&#46; Therefore&#44; studies with representative samples&#44; with an increase in the racial and ethnic groups and that contemplate the initial&#44; middle&#44; and late phases of adolescence are still necessary&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">Some authors also suggest that prospective studies be carried out to observe students&#8217; behavior during the transition period from elementary to high school&#44; as well as evaluate the onset period of the first symptoms of SAD and the risks for alcohol use&#59; assess the reasons for alcohol use&#59; evaluate treatment and its effects on adolescents&#59; and to implement corrective intervention guidelines for alcohol use among socially anxious students&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Conflicts of interest</span><p id="par0190" class="elsevierStylePara elsevierViewall">The authors declare no conflicts of interest&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To identify the risk factors related to the association between social anxiety disorder and alcohol use in adolescents&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Source of data</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The PICO research strategy was used to perform a systematic review in Medline&#44; LILACS&#44; Pubmed&#44; IBECS and Cochrane Library databases&#46; DeCS&#47;MeSH&#58; Phobic Disorders&#44; Adolescent&#44; Behavior&#44; Ethanol&#44; Risk Factors&#44; and the Boolean operator &#8220;AND&#8221; were used&#46; Inclusion criteria were&#58; cross-sectional&#44; prospective&#47;retrospective cohort&#44; and case-control studies&#44; carried out in adolescents &#40;10&#8211;19 years&#41;&#44; original articles on social anxiety disorder and alcohol use published between 2010 and 2015&#46; Studies that did not report the terms &#8220;anxiety disorder&#8221; and &#8220;alcohol use&#8221; in the title and abstract were excluded&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Synthesis of data</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">409 articles were retrieved&#59; after the exclusion of 277 repeated articles&#44; the following were eligible&#58; 94 in MEDLINE&#44; 68 in Pubmed&#44; 12 in IBCS&#44; and three in LILACS&#46; Titles and abstracts were independently read by two examiners&#44; which resulted in the selection of eight articles for the analysis&#46; Risk factors associated to the two disorders were female gender&#44; age&#44; peer approval and affective problems for alcohol use&#44; confrontation situations and&#47;or compliance reasons&#44; frequency of alcohol use&#44; and secondary comorbidities&#44; such as depression and generalized anxiety&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">It is necessary to assess the period of social anxiety disorders first symptom onset&#44; as well as the risks for alcohol use in order to establish corrective intervention guidelines&#44; especially for socially anxious students&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objective"
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          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Source of data"
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            "identificador" => "abst0015"
            "titulo" => "Synthesis of data"
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      "pt" => array:3 [
        "titulo" => "Resumo"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Identificar os fatores de risco relacionados a associa&#231;&#227;o entre o transtorno de ansiedade social e uso de &#225;lcool entre adolescentes&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Fontes dos dados</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Utilizou-se a estrat&#233;gia de pesquisa PICO para realizar a revis&#227;o sistem&#225;tica nas bases Medline&#44; LILACS&#44; Pubmed&#44; IBECS e Biblioteca Cochrane&#46; Foi utilizado os DeCS&#47;MeSH&#58; Transtornos F&#243;bicos&#44; Adolescente&#44; Comportamento&#44; Etanol&#44; Fatores de Risco e o operador boleano &#8220;AND&#8221;&#46; Os crit&#233;rios de inclus&#227;o foram&#58; estudo transversal&#44; coorte prospectiva&#47;retrospectiva e caso-controle&#44; realizados em adolescentes &#40;10 a 19 anos&#41;&#44; artigos originais sobre transtorno de ansiedade social e uso de &#225;lcool publicado entre 2010 a 2015&#46; Exclu&#237;ram-se os estudos que n&#227;o referiam transtorno de ansiedade e uso de &#225;lcool no t&#237;tulo e no resumo&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">S&#237;ntese dos dados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">409 artigos foram identificados e ap&#243;s exclus&#227;o repetidos 277 estudos foram eleg&#237;veis&#58; 94 no MEDLINE&#44; 68 em Pubmed&#44; 12 IBCS e 3 LILACS&#46; Foi realizada a leitura dos t&#237;tulos e resumos de forma independente por dois examinadores&#44; que resultou na sele&#231;&#227;o de 8 artigos para an&#225;lise&#46; Fatores de riscos associados aos dois transtornos&#58; predomin&#226;ncia do g&#234;nero feminino&#44; idade&#44; aprova&#231;&#245;es pelos pares e problemas afetivos para o uso de &#225;lcool&#44; situa&#231;&#245;es de enfrentamentos e&#47;ou motivos de conformidades&#44; frequ&#234;ncia de uso do &#225;lcool e comorbidades secund&#225;rias como depress&#227;o e ansiedade generalizada&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#245;es</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">&#201; necess&#225;rio avaliar o per&#237;odo de surgimento dos primeiros sintomas de transtorno de ansiedade social e dos riscos para o uso de &#225;lcool e instituir normas corretivas de interven&#231;&#245;es&#44; principalmente para os alunos socialmente ansiosos&#46;</p></span>"
        "secciones" => array:4 [
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            "identificador" => "abst0025"
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            "titulo" => "Fontes dos dados"
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          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "S&#237;ntese dos dados"
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            "identificador" => "abst0040"
            "titulo" => "Conclus&#245;es"
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    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Cruz EL&#44; Martins PD&#44; Diniz PR&#46; Factors related to the association of social anxiety disorder and alcohol use among adolescents&#58; a systematic review&#46; J Pediatr &#40;Rio J&#41;&#46; 2017&#59;93&#58;442&#8211;51&#46;</p>"
      ]
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        "fuente" => "<span class="elsevierStyleItalic">Source</span>&#58; &#8220;Prisma&#58; Transparent Reporting of Systematic Reviews and Meta-Analyses&#8221;&#46;"
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          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Flowchart representing the selection steps of articles about social anxiety disorder and alcohol abuse in adolescents&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Authors&#44; year&#44; and impact factor &#40;IF&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Country&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Study duration and sample&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Gender and age&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Type of study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Research tool&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Fr&#246;jd et al&#46; &#40;2011&#41;<br>IF&#58; 1&#46;09&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Finland&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48 months<br>Sample&#58; 2070&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Boys&#58; 903<br>Girls&#58; 1167<br>Mean age&#58; 17&#46;6 &#40;SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;41&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Longitudinal study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Social Phobia Inventory &#40;SPIN&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Terlecki et al&#46; &#40;2012&#41;<br>IF&#58; 1&#46;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">USA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Sample&#58; 52&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Boys&#58; 35<br>Girls&#58; 17<br>Mean age&#58; 20&#46;38 &#40;SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;46&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Longitudinal study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Alcohol Use<br>Disorder Identification Test &#40;AUDIT&#41;<br>Brief Alcohol Screening and Intervention for College<br>Students &#40;BASICS&#41;<br>Quantity&#47;Frequency&#47;Peak Index &#40;QFI&#41;<br>Drinking Norms Rating Form &#40;DNRF&#41;<br>Social Phobia Scale &#40;SPS&#41; and the Social Interaction Anxiety Scale &#40;SIAS&#41;<br>Spielberger Trait Anxiety Inventory&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Dahne et al&#46; &#40;2014&#41;<br>IF&#58; 1&#46;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">USA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48 months<br>Sample&#58; 277&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Boys&#58; 156<br>Girls&#58; 121<br>Mean age de 11 &#40;SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;81&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Longitudinal study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Generalized estimating equations &#40;GEE&#41;<br>The Revised Child Anxiety and Depression Scale &#40;RCADS&#41;<br>Youth Risk Behavior Surveillance System&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Zehe et al&#46; &#40;2013&#41;<br>IF&#58; 1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">USA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12 months<br>Sample&#58; 387&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Boys&#58; 174<br>Girls&#58; 213<br>Mean age&#58; 12&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Longitudinal study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Social Anxiety Scale For Children &#8211; Revised &#40;SASC-R&#41;<br>Youth Self-Report Survey &#40;YSR&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Terlecki and Buckner &#40;2015&#41;<br>IF&#58; 1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">USA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Sample&#58; 232&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Boys&#58; 71<br>Girls&#58; 161<br>Mean age&#58; 19&#46;32 &#40;SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;34&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Cross-sectional study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Social Phobia Scale &#40;SPS&#41;<br>Social Interaction Anxiety Scale &#40;SIAS&#41;<br>Drinking Motives Questionnaire Revised &#40;DMQR&#41;<br>Drinking Context Scale-Revised &#40;DCS-R&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Blumenthal et al&#46; &#40;2010&#41;<br>IF&#58; 1&#46;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">USA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Sample&#58; 50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Boys&#58; 24<br>Girls&#58; 26<br>Mean age 16&#46;35 &#40;SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Cross-sectional study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Adolescent Alcohol and Drug Involvement Scale &#40;AADIS&#41;<br>Youth Self Report &#40;YSR&#41;<br>Drinking Motives Questionnaire Revised &#40;DMQ-R&#41;<br>Revised Child Anxiety and Depression Scale &#8211; Social phobia subscale &#40;RCADSSP&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Wu et al&#46; &#40;2010&#41;<br>IF&#58; 1&#46;47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">USA<br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Sample&#58; 781&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Boys&#58; 412<br>Girls&#58; 369<br>Mean age&#58; 15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Cross-sectional study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Diagnostic Interview Schedule for Children &#40;DISC&#41;<br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Clerkin&#46; Barnett &#40;2012&#41;<br>IF&#58; 1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">USA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">12 months<br>Sample&#58; 730&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Boys&#58; 295<br>Girls&#58; 435<br>Mean age 18&#46;35 &#40;SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;47&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Cross-sectional study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Social Avoidance and Distress Scale &#40;SADS&#41;<br>Drinking Motives Questionnaire &#8211; Revised<br>The Graduated Frequency for Alcohol Questionnaire<br>Young Adult Alcohol Problems Screening Test&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Authors&#44; year and impact factor &#40;IF&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Objective&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Analyzed risk factors&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Results&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Conclusions&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Fr&#246;jd et al&#46; &#40;2011&#41;<br>IF&#58; 1&#46;09&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">To investigate whether the association between anxiety and alcohol and other substances are already evident in the middle adolescence&#44; and whether the general anxiety or social phobia symptoms affects the continuity of frequent use of alcohol&#44; frequent drunkenness&#44; and marijuana use&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Generalized anxiety<br>Social phobia<br>Substance use<br>Frequency of use<br>Drunkenness frequency<br>Use of marijuana&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Anxiety preceded the use of the substance&#44; while no reciprocal associations were observed&#46;<br>Depression-mediated associations between anxiety and substance use&#46;<br>Symptoms of social phobia did not increase the incidence of substance use&#44; but overall anxiety&#46;<br>General anxiety increased the persistence of frequent alcohol use&#44; while co-morbid social phobia decreased its persistence&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">General anxiety in adolescence puts adolescents at risk for substance use&#46; The risk may&#44; however&#44; be associated with depression&#46; Social phobia in middle adolescence may protect against substance use&#46;<br>Adolescents with symptoms of internalization may need guidance in coping with symptoms&#44; even though the symptoms did not meet the criteria of mood or anxiety disorder&#46;<br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Terlecki et al&#46; &#40;2012&#41;<br>IF&#58; 1&#46;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">To evaluate whether socially anxious students showed less change in alcohol use behavior among college students&#46;<br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Social anxiety<br>Typical drinks<br>Rules for drinking&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Among students with minor changes in rules&#44; being a member of a group with social anxiety was associated with heavier drinking of typical drinks&#46;<br>Among students with major changes in rules&#44; being a member of a social anxiety group was not significant&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Generalized anxiety in middle adolescence puts adolescents at risk for concomitant substance use and subsequently in late adolescence&#46;<br>The risk may&#44; however&#44; be associated with depression&#46;<br>Social anxiety and use of alcohol or substance was not observed in middle and late adolescence&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Dahne et al&#46; &#40;2014&#41;<br>IF&#58; 1&#46;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">To assess whether social phobia symptoms predicted increased likelihood of alcohol use over time&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Demographic data<br>Psychopathology<br>Alcohol use&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">There were correlations between the baseline predictors &#40;child&#39;s age&#44; child&#39;s gender&#44; baseline alcohol use&#44; social phobia symptoms&#41; and waves 1&#8211;5 alcohol use<br>In general&#44; the concurrent associations were low to moderate&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">It highlights the importance of social phobia symptoms in predicting alcohol use over time among young adolescents&#46;<br>Several future directions within this line of research would be valuable&#44; including expanding the assessed age range to younger children and adolescents&#47;older young adults&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Zehe et al&#46; &#40;2013&#41;<br>IF&#58; 1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">To assess the association between social and generalized anxiety symptoms and alcohol and cigarette use in early adolescence and as a precautionary measure &#40;perceived peer use approval&#41; and &#40;perceived use point&#41; descriptive rules may moderate the association&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Peer norms<br>Gender differences&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Peer norms were moderated for the association between social anxiety symptoms&#44; generalized anxiety&#44; and the likelihood of alcohol and cigarette use by girls&#44; but not for boys&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Girls with high levels of social anxiety symptoms were at risk for use when perceived peer approval of use was high&#44; and protected from use when perceived peer approval of use was low&#46;<br>Profiles of anxiety symptoms and perceived peer approval of use may help identify girls who are potential targets for intervention&#44; but the nature of these interventions is still unclear&#44; since this study did not assess the potential risk mechanisms&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Terlecki and Buckner &#40;2015&#41;<br>IF&#58; 1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Identify cognitive&#47;motivational factors related to drinking in high-risk situations&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Demographic data<br>Social anxiety and Reasons to drink&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">High social anxiety was associated with greater coping and compliance reasons&#46;<br>Both coping and compliance motives were mediated&#44; the association between social anxiety to heavy alcohol consumption to negative emotional and personal&#47;intimate contexts&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Multiple mediation analysis has indicated that to mediate anxiety situations university students drink socially&#44; such that heavy drinking among college students with clinically elevated social anxiety can be attributed jointly to the desire to deal with negative affect and to avoid social scrutiny&#46;<br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Blumenthal et al&#46; &#40;2010&#41;<br>IF&#58; 1&#46;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">To assess the reasons for alcohol use among young individuals as a function of social anxiety&#44; associated variables &#40;age&#44; gender&#44; frequency of alcohol use&#44; affective problems&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Age<br>Frequency of alcohol use<br>Affective problems&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">High social anxiety was significantly associated with a high level of affective problems&#44; as well as with coping reasons&#46;<br>Social anxiety was significantly associated with coping motives&#44; so that young individuals who had high social anxiety reported greater motivation to drink for coping-related purposes&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Socially anxious young individuals endorse higher consumption motives&#44; related to coping issues&#44; a characteristic that may put them at risk for developing alcoholism problems&#46;<br>Prospective studies focused on clarifying associations between adolescent social anxiety&#44; dealing with reasons for drinking and problematic use of alcohol&#44; with the ultimate goal of designing prevention programs targeting young individuals at risk for social anxiety&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Wu et al&#46; &#40;2010&#41;<br>IF&#58; 1&#46;47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">To assess the use of three substance categories by adolescents &#40;frequent smoking&#44; frequent drinking&#47;heavy use&#44; and use of illicit drugs&#41; in relation to each of the six anxiety disorders &#40;social phobia&#44; agoraphobia&#44; high anxiety disorder&#47;generalized anxiety disorder&#44; separation anxiety&#44; and obsessive-compulsive disorder&#41;&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Substance use<br>Anxiety disorder<br>Demographics and family factors<br>Depression&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Social phobia was associated with smoking only among boys&#46; For girls&#44; social phobia appeared to be negatively associated with drug use&#46;<br>For the other anxiety disorders&#44; associations with substance use tend to be stronger among girls&#46;<br>There was an association between social anxiety symptoms and alcohol use only in girls&#46; Frequent or heavy drinking was more common among boys than girls&#44; but this difference was only marginally significant&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">The differences between the patterns observed in the study sample of adolescents and the results of studies with adults regarding social phobia to some extent indicate that the association between anxiety disorders and substance use may change from adolescence to adulthood&#46;<br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Clerkin and Barnett &#40;2012&#41;<br>IF&#58; 1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">To test the separate and interactive effects of drinking motives and social anxiety symptoms in predicting drinking and drinking-related problems&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Social anxiety symptoms<br>Reasons to drink<br>Alcohol consumption<br>Problems with alcohol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Increased social anxiety symptoms were significantly associated with less alcohol consumption&#44; and there was some evidence that greater social anxiety symptoms were also associated with greater problems with alcohol&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">The main effects of social anxiety symptoms and consumption motives were more influential in predicting consumption outcomes&#46;<br>Greater social anxiety was associated with greater endorsement of coping and compliance motives&#44; and less endorsement of reasons for enhancement&#46;<br>Symptoms of social anxiety were associated to lower alcohol consumption&#44; and also with more problems with drinking&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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Article information

ISSN: 00217557
Original language: English

DOI:10.1016/j.jped.2017.05.001

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Year/Month	Html	Pdf	Total

2024 November	4	1	5
2024 October	24	24	48
2024 September	47	23	70
2024 August	42	39	81
2024 July	36	34	70
2024 June	21	15	36
2024 May	17	7	24
2024 April	24	23	47
2024 March	28	17	45
2024 February	29	19	48
2024 January	24	23	47
2023 December	20	26	46
2023 November	18	28	46
2023 October	25	31	56
2023 September	51	33	84
2023 August	40	13	53
2023 July	35	17	52
2023 June	20	7	27
2023 May	28	13	41
2023 April	24	7	31
2023 March	46	16	62
2023 February	28	20	48
2023 January	33	24	57
2022 December	56	19	75
2022 November	33	29	62
2022 October	24	29	53
2022 September	22	35	57
2022 August	34	30	64
2022 July	52	34	86
2022 June	50	33	83
2022 May	47	27	74
2022 April	37	30	67
2022 March	32	39	71
2022 February	26	20	46
2022 January	59	18	77
2021 December	13	19	32
2021 November	17	14	31
2021 October	16	17	33
2021 September	10	16	26
2021 August	18	11	29
2021 July	15	10	25
2021 June	8	6	14
2021 May	13	15	28
2021 April	17	16	33
2021 March	25	8	33
2021 February	10	6	16
2021 January	7	14	21
2020 December	12	11	23
2020 November	8	11	19
2020 October	9	7	16
2020 September	11	10	21
2020 August	5	1	6
2020 July	5	4	9
2020 June	14	5	19
2020 May	6	3	9
2020 April	7	14	21
2020 March	4	2	6
2020 February	22	15	37
2020 January	9	17	26
2019 December	1	5	6
2019 November	4	7	11
2019 October	12	14	26
2019 September	8	11	19
2019 August	8	8	16
2019 July	11	11	22
2019 June	14	17	31
2019 May	9	22	31
2019 April	23	7	30
2019 March	16	6	22
2019 February	5	7	12
2019 January	6	6	12
2018 December	14	6	20
2018 November	48	6	54
2018 October	69	14	83
2018 September	16	11	27
2018 August	12	4	16
2018 July	5	4	9
2018 June	12	5	17
2018 May	22	8	30
2018 April	13	3	16
2018 March	21	5	26
2018 February	11	5	16
2018 January	6	5	11
2017 December	11	4	15
2017 November	24	10	34
2017 October	31	17	48
2017 September	9	9	18
2017 August	1	8	9
2017 July	0	8	8
2017 June	0	9	9

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