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visto que exerce um papel fundamental no desenvolvimento do risco cardiometab&#243;lico&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Existem diferentes t&#233;cnicas para avaliar a adiposidade corporal&#44; a absorciometria de raios X de dupla energia &#40;DXA&#41; &#233; considerada um m&#233;todo refer&#234;ncia para avaliar a adiposidade central em crian&#231;as de todas as idades&#44; pois estima a quantidade de gordura na regi&#227;o androide&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">4</span></a> No entanto&#44; sua aplica&#231;&#227;o em estudos epidemiol&#243;gicos e na pr&#225;tica cl&#237;nica tamb&#233;m &#233; limitada por apresentar custo elevado e execu&#231;&#227;o complexa&#44; s&#227;o necess&#225;rios m&#233;todos simples e menos dispendiosos&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Nesse aspecto&#44; o per&#237;metro do pesco&#231;o &#40;PP&#41; tem sido proposto como uma ferramenta &#250;til para identificar indiv&#237;duos jovens com excesso de peso e risco cardiometab&#243;lico por ser um m&#233;todo simples&#44; de baixo custo e ter uma menor varia&#231;&#227;o ao longo do dia comparado ao per&#237;metro da cintura&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">5</span></a> No entanto&#44; at&#233; o momento&#44; n&#227;o foram encontrados estudos na literatura que avaliaram a associa&#231;&#227;o e a capacidade do PP de identificar o excesso de adiposidade central estimada por um m&#233;todo refer&#234;ncia&#44; como a gordura na regi&#227;o androide determinada pelo DXA&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">A aus&#234;ncia da defini&#231;&#227;o de pontos de corte espec&#237;ficos de PP para crian&#231;as brasileiras pode ser uma limita&#231;&#227;o para seu uso rotineiro&#46; Na literatura&#44; segundo o nosso conhecimento&#44; encontra&#8208;se apenas um estudo de delineamento transversal com adolescentes brasileiros matriculados em escolas p&#250;blicas do munic&#237;pio de S&#227;o Paulo&#8208;SP que prop&#244;s pontos de corte de PP para identificar sobrepeso e obesidade&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">6</span></a> Diante disso&#44; s&#227;o escassos os estudos com essa abordagem em idades mais precoces&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Assim&#44; o objetivo deste estudo foi&#58; 1&#41; avaliar a capacidade do PP de identificar o excesso de gordura androide&#59; 2&#41; propor pontos de corte de PP para determinar o excesso de gordura androide em crian&#231;as brasileiras&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">M&#233;todos</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Popula&#231;&#227;o e delineamento do estudo</span><p id="par0035" class="elsevierStylePara elsevierViewall">Estudo transversal feito com amostra representativa de crian&#231;as de oito e nove anos&#44; matriculadas em escolas p&#250;blicas e privadas da &#225;rea urbana do munic&#237;pio de Vi&#231;osa&#8208;MG&#44; de maio a dezembro de 2015&#46; O munic&#237;pio de Vi&#231;osa fica na Zona da Mata Mineira&#44; a 227<span class="elsevierStyleHsp" style=""></span>km da capital Belo Horizonte&#46; De acordo com o Censo 2010&#44; Vi&#231;osa apresenta uma extens&#227;o territorial de 299 km<span class="elsevierStyleSup">2</span> e 72&#46;244 habitantes&#44; 93&#44;2&#37; residem em &#225;rea urbana&#46; O Produto Interno Bruto &#40;PIB&#41; <span class="elsevierStyleItalic">per capita</span> &#233; de R&#36; <span class="elsevierStyleItalic">19&#46;391&#44;08</span>&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">7</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Os participantes deste estudo foram provenientes da Pesquisa de Avalia&#231;&#227;o da Sa&#250;de do Escolar &#40;PASE&#41;&#44; investiga&#231;&#227;o transversal que teve o objetivo de avaliar a sa&#250;de cardiovascular desse p&#250;blico infantil no munic&#237;pio de Vi&#231;osa&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">8</span></a> Em 2015&#44; o munic&#237;pio contava com 17 escolas p&#250;blicas e sete particulares na &#225;rea urbana que atendiam crian&#231;as de oito e nove anos&#44; total de 1&#46;464 crian&#231;as matriculadas&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">C&#225;lculo amostral e processo de amostragem</span><p id="par0045" class="elsevierStylePara elsevierViewall">O c&#225;lculo amostral foi feito no <span class="elsevierStyleItalic">software</span> Epi Info &#40;vers&#227;o 7&#46;2&#59; Atlanta&#44; GA&#41;&#44; considerando o n&#250;mero total de estudantes de oito e nove anos em 2015 &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;464&#41;&#44; preval&#234;ncia de 10&#44;7&#37; de obesidade&#44;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">9</span></a> erro tolerado de 3&#37;&#44; n&#237;vel de confian&#231;a de 95&#37; e acr&#233;scimo de 20&#37; para cobertura de perdas&#44; total de 384 crian&#231;as a serem estudadas&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">As crian&#231;as foram selecionadas por amostragem aleat&#243;ria estratificada&#44; a amostra de cada escola atingiu a proporcionalidade dos alunos matriculados por idade e sexo&#46; A sele&#231;&#227;o de crian&#231;as foi feita por sorteio aleat&#243;rio simples at&#233; que o n&#250;mero necess&#225;rio para cada escola fosse alcan&#231;ado&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Ap&#243;s a sele&#231;&#227;o&#44; fez&#8208;se contato telef&#244;nico com os respons&#225;veis pelas crian&#231;as&#44; as quais foram convidadas a participar do estudo&#46; Foram explicados os objetivos e a metodologia do estudo e foi agendado o primeiro encontro&#44; no qual&#44; ap&#243;s explica&#231;&#227;o de cada etapa aos respons&#225;veis&#44; aqueles que concordaram em participar assinaram o Termo de Consentimento Livre e Esclarecido &#40;TCLE&#41;&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">N&#227;o foram inclu&#237;das crian&#231;as que apresentassem algum problema de sa&#250;de que alterasse o estado nutricional ou a composi&#231;&#227;o corporal &#40;defici&#234;ncias f&#237;sicas&#44; cognitivas ou m&#250;ltiplas&#44; dist&#250;rbios da tireoide etc&#46;&#41;&#44; bem como em uso cr&#244;nico de medicamentos que interferissem no metabolismo da glicose e&#47;ou lip&#237;dios &#40;corticosteroides&#44; estatinas&#44; hipoglicemiantes etc&#46;&#41; e em uso de suplementos vitam&#237;nicos ou minerais no decorrer da pesquisa ou nos &#250;ltimos tr&#234;s meses &#40;suplementa&#231;&#227;o de vitamina D e zinco&#41;&#46; E ainda nos casos de impossibilidade de contato com os pais ou respons&#225;vel ap&#243;s tr&#234;s tentativas&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Foi feito em fevereiro de 2015 um estudo&#8208;piloto com 10&#37; da amostra&#44; que incluiu crian&#231;as de oito e nove anos matriculadas em uma escola p&#250;blica&#44; selecionada de forma aleat&#243;ria&#44; as quais n&#227;o fizeram parte da amostra final do estudo&#46; Por meio do estudo piloto&#44; foi poss&#237;vel testar a aplica&#231;&#227;o dos question&#225;rios&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Dados demogr&#225;ficos&#44; socioecon&#244;micos e de estilo de vida</span><p id="par0070" class="elsevierStylePara elsevierViewall">Foi aplicado um question&#225;rio semiestruturado com informa&#231;&#245;es socioecon&#244;micas e demogr&#225;ficas&#44; como idade&#44; sexo&#44; tipo de escola &#40;p&#250;blica ou privada&#41; e renda <span class="elsevierStyleItalic">per capita</span> &#40;categorizada de acordo com a mediana da amostra total&#44; equivalente a R&#36; 500&#44;00&#41;&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Um question&#225;rio sobre estilo de vida foi aplicado para estimar o tempo de tela em horas por dia &#40;tempo gasto sentado por longos per&#237;odos na frente da televis&#227;o&#44; videogame ou computador&#41;&#46; O comportamento sedent&#225;rio foi classificado como tempo de tela maior do que duas horas&#47;dia&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">10</span></a></p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Antropometria e composi&#231;&#227;o corporal</span><p id="par0080" class="elsevierStylePara elsevierViewall">A coleta de dados foi feita em ambiente apropriado por um membro da equipe treinado&#44; com os volunt&#225;rios sem cal&#231;ados e com roupas leves&#46; O peso foi aferido em balan&#231;a digital eletr&#244;nica&#44; com capacidade de 150<span class="elsevierStyleHsp" style=""></span>kg e precis&#227;o de 0&#44;1<span class="elsevierStyleHsp" style=""></span>kg &#40;<span class="elsevierStyleItalic">Tanita</span>&#174; Modelo Ironman BC 553&#44; Tanita Corporation of America Inc&#46;&#44; Artlington Heights&#44; USA&#41; e a estatura foi determinada com um estadi&#244;metro&#44; dividido em cent&#237;metros e subdividido em mil&#237;metros &#40;<span class="elsevierStyleItalic">Alturexata</span>&#174;&#44; Belo Horizonte&#44; Brasil&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Com os dados de peso e estatura obtidos&#44; foi calculado o &#237;ndice de massa corporal &#40;IMC&#41; e para a classifica&#231;&#227;o do estado nutricional das crian&#231;as&#44; foram usados os pontos de corte de IMC por idade &#40;IMC&#47;I&#41; em escore&#8208;z&#44; estabelecidos pela Organiza&#231;&#227;o Mundial da Sa&#250;de&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">11</span></a> Para avalia&#231;&#227;o do estado nutricional das m&#227;es&#44; foram adotados os crit&#233;rios para classifica&#231;&#227;o do IMC preconizados pela Organiza&#231;&#227;o Mundial de Sa&#250;de&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">12</span></a> Crian&#231;as e m&#227;es com sobrepeso e obesidade foram agrupadas em excesso de peso&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">O PP foi avaliado com a crian&#231;a em p&#233;&#44; ereta com a cabe&#231;a&#44; no plano horizontal de Frankfurt&#44; com uma fita m&#233;trica inextens&#237;vel &#40;<span class="elsevierStyleItalic">TBW</span>&#174;&#44; S&#227;o Paulo&#44; Brasil&#41;&#44; exatamente abaixo da proemin&#234;ncia lar&#237;ngea no pesco&#231;o&#44; perpendicularmente ao maior eixo do pesco&#231;o&#46; Foi exercida press&#227;o m&#237;nima&#44; de forma que permitisse o contato completo da fita com a pele&#46; A aferi&#231;&#227;o foi feita em duplicata&#44; foi considerada a m&#233;dia das duas medidas&#46; Para classifica&#231;&#227;o&#44; foram usados os pontos de corte obtidos nas curvas <span class="elsevierStyleItalic">Receiver Operating Characteristic</span> &#40;ROC&#41; com melhores valores de sensibilidade&#44; especificidade e valores preditivos para excesso gordura androide&#44; de acordo com o sexo&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">O percentual de gordura na regi&#227;o androide foi determinado pela absorciometria de raios X de dupla energia &#40;DXA&#41; &#40;Lunar Prodigy Advance&#59; GE Medical Systems Lunar&#44; Milwaukee&#44; WI&#44; USA&#41;&#44; usou&#8208;se o <span class="elsevierStyleItalic">software</span> do pr&#243;prio equipamento para an&#225;lise de composi&#231;&#227;o corporal&#46; A gordura androide foi identificada na regi&#227;o entre as costelas e a pelve&#44; a demarca&#231;&#227;o superior foi feita a 20&#37; da dist&#226;ncia da crista il&#237;aca e do pesco&#231;o e a demarca&#231;&#227;o inferior feita acima da pelve&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">4</span></a> N&#227;o foram encontrados na literatura pontos de corte para o diagn&#243;stico de gordura androide elevada em crian&#231;as&#46; Por isso&#44; considerou&#8208;se como valores aumentados o percentil 85<span class="elsevierStyleHsp" style=""></span>da amostra de acordo com o sexo&#44; que corresponderam aos valores de 34&#44;0&#37; e 28&#44;9&#37; para meninas e meninos&#44; respectivamente&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Avalia&#231;&#227;o bioqu&#237;mica e de press&#227;o arterial</span><p id="par0100" class="elsevierStylePara elsevierViewall">A coleta de sangue foi feita ap&#243;s jejum de 12 horas no Laborat&#243;rio de An&#225;lises Cl&#237;nicas da Divis&#227;o de Sa&#250;de da Universidade Federal de Vi&#231;osa &#40;UFV&#41;&#46; As amostras foram coletadas por pun&#231;&#227;o venosa em tubo soro&#44; foram centrifugadas por 15 minutos a 3&#46;500<span class="elsevierStyleHsp" style=""></span>rpm e depois separadas em <span class="elsevierStyleItalic">eppendorfs</span> de 1&#44;5<span class="elsevierStyleHsp" style=""></span>mL e armazenadas em <span class="elsevierStyleItalic">ultrafreezer</span> a &#8208;80<span class="elsevierStyleHsp" style=""></span>&#176;C&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">O perfil lip&#237;dico &#40;colesterol total&#44; lipoprote&#237;na de alta densidade &#8208; HDL&#8208;c&#44; lipoprote&#237;na de baixa densidade &#8208; LDL&#8208;c e triglicer&#237;deo&#41; e a glicemia de jejum foram determinados pelo m&#233;todo enzim&#225;tico colorim&#233;trico&#44; usou&#8208;se kit comercial Bioclin&#174; &#40;Belo Horizonte&#44; MG&#44; Brasil&#41; e foram dosados em equipamento analisador autom&#225;tico &#40;BS&#8208;200 Mindray&#174;&#44; Nanshan&#44; China&#41; no Laborat&#243;rio de An&#225;lises Cl&#237;nicas &#40;LAC&#41; do Departamento de Nutri&#231;&#227;o e Sa&#250;de da UFV&#46; A classifica&#231;&#227;o dos componentes do perfil lip&#237;dico foi feita de acordo com a Atualiza&#231;&#227;o da Diretriz Brasileira de Dislipidemias e Preven&#231;&#227;o da Aterosclerose&#46;<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">13</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">A insulina de jejum foi determinada pelo m&#233;todo de imunoensaio por quimioluminesc&#234;ncia no laborat&#243;rio Diagn&#243;sticos do Brasil&#44; foi quantificada pelo teste&#160;Elecsys Insulin&#174; com limite de detec&#231;&#227;o de 0&#44;200&#8208;1&#46;000<span class="elsevierStyleHsp" style=""></span>&#956;U&#47;mL&#46; Para a classifica&#231;&#227;o da resist&#234;ncia &#224; insulina&#44; foi usado o valor de HOMA&#8208;IR maior ou igual a 3&#44;16&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">14</span></a></p><p id="par0115" class="elsevierStylePara elsevierViewall">Para aferir a press&#227;o arterial usou&#8208;se um equipamento eletr&#244;nico digital no bra&#231;o com infla&#231;&#227;o e defla&#231;&#227;o autom&#225;tica do ar&#44; o tamanho do manguito foi apropriado para o paciente&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a> Para avaliar a press&#227;o arterial consideraram&#8208;se sexo&#44; idade e percentil de estatura&#44; tamb&#233;m de acordo com a classifica&#231;&#227;o preconizada pela Sociedade Brasileira de Cardiologia&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a></p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">An&#225;lises estat&#237;sticas</span><p id="par0120" class="elsevierStylePara elsevierViewall">Foram feitas no <span class="elsevierStyleItalic">software Statistical Package for the Social Sciences for</span><span class="elsevierStyleItalic">Windows</span>&#44; vers&#227;o 23&#46;0 &#40;SPSS Inc&#46; Chicago&#44; USA&#41;&#46; O teste de normalidade de Kolmogorov&#8208;Smirnov foi usado para determinar se as vari&#225;veis quantitativas cont&#237;nuas apresentavam distribui&#231;&#227;o normal&#46; O n&#237;vel de signific&#226;ncia adotado para todos os testes de hip&#243;teses foi de 5&#37;&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Foram feitas an&#225;lises descritivas dos dados&#44; por meio de frequ&#234;ncias relativas&#44; m&#233;dias &#40;desvio&#8208;padr&#227;o&#41; ou medianas &#40;intervalo interquartil&#41;&#46; Para compara&#231;&#227;o de m&#233;dias ou medianas entre duas amostras independentes foram feitos os testes <span class="elsevierStyleItalic">t</span> de Student ou de Mann&#8208;Whitney&#44; respectivamente&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">A associa&#231;&#227;o entre o PP &#40;vari&#225;vel independente&#41; e a gordura androide &#40;vari&#225;vel dependente&#41; foi avaliada pela regress&#227;o linear m&#250;ltipla&#46; As vari&#225;veis de ajuste que compuseram o modelo final foram&#58; sexo&#44; tipo de escola &#40;p&#250;blica ou privada&#41;&#44; colesterol total&#44; HDL&#8208;c&#44; HOMA&#8208;IR e IMC materno&#46; O modelo final foi avaliado de acordo com os pressupostos da linearidade&#44; homocedasticidade&#44; normalidade&#44; independ&#234;ncia&#44; multicolinearidade e res&#237;duos padronizados&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">As curvas <span class="elsevierStyleItalic">Receiver Operating Characteristic</span> &#40;ROC&#41; determinaram a capacidade do PP de identificar o excesso de gordura androide&#46; Al&#233;m disso&#44; foram estimados os pontos de corte de PP com melhores valores de sensibilidade &#40;S&#41; e especificidade &#40;E&#41;&#44; valores preditivos positivo &#40;VPP&#41; e negativo &#40;VPN&#41;&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Aspectos &#233;ticos</span><p id="par0140" class="elsevierStylePara elsevierViewall">Este estudo foi feito de acordo com as diretrizes estabelecidas na Declara&#231;&#227;o de Helsinque e aprovado pelo Comit&#234; de &#201;tica em Pesquisa com Seres Humanos da Universidade Federal de Vi&#231;osa &#40;parecer n&#176; 663&#46;171&#47;2014&#41;&#46; O mesmo tamb&#233;m foi aprovado pela Secretaria Municipal de Educa&#231;&#227;o&#44; Superintend&#234;ncia Regional de Ensino e dire&#231;&#227;o das escolas&#46;</p></span></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Resultados</span><p id="par0145" class="elsevierStylePara elsevierViewall">A amostra final foi constitu&#237;da por 376 crian&#231;as&#44; houve perda de 2&#44;1&#37; dos participantes por n&#227;o completarem todas as etapas da pesquisa &#40;n&#227;o fizeram a coleta de sangue para exames bioqu&#237;micos&#41;&#46; A partir dos pontos de cortes propostos nas curvas ROC&#44; observou&#8208;se que 20&#44;2&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>76&#41; das crian&#231;as apresentaram PP elevado &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0150" class="elsevierStylePara elsevierViewall">Na amostra geral&#44; o PP e o percentual de gordura androide apresentaram medianas de 27&#44;0<span class="elsevierStyleHsp" style=""></span>cm e 14&#44;9&#37;&#44; respectivamente&#46; Observaram&#8208;se maiores percentuais de gordura androide em crian&#231;as do sexo feminino&#44; de escolas privadas&#44; com excesso de peso&#44; perfil lip&#237;dico indesejado&#44; resist&#234;ncia &#224; insulina&#44; press&#227;o arterial elevada e excesso de peso materno&#46; Os mesmos resultados foram encontrados para os maiores valores do PP&#44; com exce&#231;&#227;o para o tipo de escola&#44; colesterol total e LDL&#8208;c &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">No modelo final de regress&#227;o linear m&#250;ltipla&#44; observou&#8208;se associa&#231;&#227;o positiva entre o PP e o percentual de gordura androide&#46; O aumento em 1<span class="elsevierStyleHsp" style=""></span>cm no PP esteve associado ao aumento de 2&#44;94&#37; na gordura androide&#44; ao ser ajustado por sexo&#44; tipo de escola&#44; colesterol total&#44; HDL&#8208;c&#44; HOMA&#8208;IR e IMC materno &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabela 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0160" class="elsevierStylePara elsevierViewall">A an&#225;lise na curva ROC demonstrou que o PP foi capaz de identificar o excesso de gordura androide em meninas &#40;AUC&#58; 0&#44;909&#59; IC95&#37;&#58; 0&#44;859&#59; 0&#44;945&#41; e meninos &#40;AUC&#58; 0&#44;938&#59; IC95&#37;&#58; 0&#44;892&#59; 0&#44;968&#41;&#46; Os pontos de corte propostos para o sexo feminino &#40;28&#44;3<span class="elsevierStyleHsp" style=""></span>cm&#41; e masculino &#40;28&#44;6<span class="elsevierStyleHsp" style=""></span>cm&#41; tiveram valores de S &#40;feminino&#58; 76&#44;1&#37;&#59; masculino&#58; 85&#44;2&#37;&#41;&#44; E &#40;feminino&#58; 92&#44;7&#37;&#59; masculino&#58; 87&#44;6&#37;&#41; e valores preditivos &#40;feminino&#58; VPP 76&#44;1&#37;&#44; VPN 92&#44;7&#37;&#59; masculino&#58; VPP 56&#44;4&#37;&#44; VPN 97&#44;1&#37;&#41; satisfat&#243;rios &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Discuss&#227;o</span><p id="par0165" class="elsevierStylePara elsevierViewall">At&#233; o presente momento&#44; este &#233; o primeiro estudo brasileiro feito com amostra representativa de crian&#231;as que demonstrou a capacidade do PP de identificar o excesso de gordura androide&#46; Ademais&#44; o PP apresentou associa&#231;&#227;o direta com a gordura androide&#44; independentemente do sexo&#44; tipo de escola&#44; das concentra&#231;&#245;es s&#233;ricas de colesterol total e HDL&#8208;c&#44; HOMA&#8208;IR e IMC materno&#46; Ressalta&#8208;se que os pontos de corte propostos apresentaram valores de S&#44; E e valores preditivos satisfat&#243;rios&#44; viabilizaram o uso do PP em estudos epidemiol&#243;gicos&#44; triagens do risco cardiometab&#243;lico e atendimentos ambulatoriais&#46;</p><p id="par0170" class="elsevierStylePara elsevierViewall">O uso do PP em adultos &#233; amplamente estudado&#44; observou&#8208;se sua associa&#231;&#227;o direta com o tecido adiposo visceral e o HOMA&#8208;IR em obesos&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">16</span></a> Al&#233;m disso&#44; um estudo de base populacional com adultos brasileiros demonstrou que o PP pode ser usado para identificar s&#237;ndrome metab&#243;lica e resist&#234;ncia &#224; insulina&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">17</span></a></p><p id="par0175" class="elsevierStylePara elsevierViewall">Nesse sentido&#44; o uso do PP na popula&#231;&#227;o pedi&#225;trica se torna importante&#44; a maioria dos estudos com esse p&#250;blico o comparou com m&#233;todos de estimativa de adiposidade duplamente indiretos&#44; como IMC&#44;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> per&#237;metro da cintura<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> e rela&#231;&#227;o cintura&#8208;estatura&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">20</span></a> Em indiv&#237;duos de nove a 13 anos da Gr&#233;cia&#44; o PP esteve associado diretamente &#224;s concentra&#231;&#245;es s&#233;ricas de triglicer&#237;deo e insulina&#44; HOMA&#8208;IR e press&#227;o arterial&#59; e inversamente &#224; concentra&#231;&#227;o s&#233;rica de HDL&#8208;c&#44; <span class="elsevierStyleItalic">quantitative insulin sensitivity check index</span> &#40;QUICKI&#41; e raz&#227;o glicose&#8208;insulina de jejum &#40;FGIR&#41;&#46; O mesmo estudo demonstrou que outras medidas antropom&#233;tricas usadas em crian&#231;as e adolescentes&#44; como escore&#8208;z de IMC&#44; per&#237;metro da cintura e do quadril&#44; rela&#231;&#227;o cintura&#8208;estatura e rela&#231;&#227;o cintura&#8208;quadril&#44; apresentaram associa&#231;&#245;es com os marcadores de risco cardiometab&#243;lico semelhantes ao PP&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">21</span></a></p><p id="par0180" class="elsevierStylePara elsevierViewall">O PP &#233; considerado uma op&#231;&#227;o para identificar adiposidade central por apresentar algumas vantagens em rela&#231;&#227;o ao per&#237;metro da cintura&#44; tais como&#58; boa concord&#226;ncia inter e intraobservador&#59; n&#227;o &#233; influenciado pelo hor&#225;rio de mensura&#231;&#227;o &#40;per&#237;odo pr&#233;&#8208;prandial e p&#243;s&#8208;prandial&#41;&#59; maior facilidade para mensurar&#44; pois n&#227;o requer que o examinado esteja com o m&#237;nimo de vestu&#225;rios&#44; &#233; assim mais aceit&#225;vel socialmente&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> Entretanto&#44; n&#227;o h&#225; um consenso internacional sobre pontos de corte a serem adotados para o p&#250;blico infantil&#46;</p><p id="par0185" class="elsevierStylePara elsevierViewall">Existem pontos de corte do PP propostos a partir de curvas ROC<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> e de percentis<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">22</span></a> para crian&#231;as e adolescentes de acordo com o sexo e a idade em diferentes localidades&#46; No entanto&#44; a grande maioria &#233; de pontos de corte capazes de determinar o excesso de peso&#47;obesidade pelo IMC&#46;<a class="elsevierStyleCrossRefs" href="#bib0240"><span class="elsevierStyleSup">18&#44;22</span></a> Por isso&#44; o presente estudo prop&#244;s pontos de corte de PP que podem ser usados para identificar o excesso de gordura androide pelo DXA&#44; que &#233; capaz de estimar adiposidade central&#44; &#233; um m&#233;todo considerado refer&#234;ncia&#46;<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">23</span></a></p><p id="par0190" class="elsevierStylePara elsevierViewall">Em estudo transversal com adolescentes brasileiros de Campinas&#8208;SP&#44; os pontos de corte de PP sugeridos para determinar resist&#234;ncia &#224; insulina foram de 32&#44;0 e 30&#44;3<span class="elsevierStyleHsp" style=""></span>cm para meninas e meninos pr&#233;&#8208;p&#250;beres&#44; respectivamente&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> Os pontos de corte propostos em estudo transversal feito por Nafiu et al&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> para identificar o excesso de peso em crian&#231;as americanas de oito e nove anos foram 29&#44;0 e 30&#44;5<span class="elsevierStyleHsp" style=""></span>cm &#40;meninos&#41;&#44; 27&#44;9 e 29&#44;3<span class="elsevierStyleHsp" style=""></span>cm &#40;meninas&#41;&#44; respectivamente&#44; pr&#243;ximos dos valores encontrados no nosso estudo&#46; Diante disso&#44; recomenda&#8208;se a valida&#231;&#227;o dos pontos de corte propostos no presente trabalho para outras popula&#231;&#245;es&#44; com o objetivo de identificar o excesso de adiposidade central e tamb&#233;m outros fatores de risco cardiometab&#243;lico&#46;</p><p id="par0195" class="elsevierStylePara elsevierViewall">S&#227;o de grande relev&#226;ncia estudos que abordam o excesso de adiposidade central no p&#250;blico infantil&#44; visto que as medidas antropom&#233;tricas que estimam adiposidade central apresentaram maior associa&#231;&#227;o com o risco cardiometab&#243;lico&#44; em rela&#231;&#227;o ao IMC em crian&#231;as&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">24</span></a> A gordura na regi&#227;o androide compreende o tecido adiposo visceral&#44; o qual &#233; mais lipol&#237;tico comparado com o das regi&#245;es perif&#233;ricas&#46; Observa&#8208;se maior libera&#231;&#227;o hep&#225;tica de LDL&#8208;c&#44; triglicer&#237;deos e outros &#225;cidos graxos na circula&#231;&#227;o portal&#44; est&#237;mulo da gliconeog&#234;nese hep&#225;tica e inibi&#231;&#227;o da capta&#231;&#227;o hep&#225;tica de insulina&#44; que causam hiperinsulinemia e resist&#234;ncia &#224; insulina&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">25</span></a></p><p id="par0200" class="elsevierStylePara elsevierViewall">Considerando as elevadas preval&#234;ncias de excesso de peso&#44; perfil lip&#237;dico indesejado e comportamento sedent&#225;rio nesta amostra e em outras pesquisas semelhantes&#44;<a class="elsevierStyleCrossRefs" href="#bib0280"><span class="elsevierStyleSup">26&#44;27</span></a> torna&#8208;se necess&#225;rio o diagn&#243;stico precoce do excesso de adiposidade central em crian&#231;as&#46; Sabe&#8208;se que todas essas altera&#231;&#245;es podem permanecer na fase adulta&#44; al&#233;m de estar relacionadas ao processo de aterog&#234;nese e a danos card&#237;acos&#44; que j&#225; podem iniciar na inf&#226;ncia&#46;<a class="elsevierStyleCrossRefs" href="#bib0290"><span class="elsevierStyleSup">28&#44;29</span></a> Ademais&#44; a avalia&#231;&#227;o do estado nutricional materno &#233; importante para identificar o excesso de adiposidade central em crian&#231;as&#44; visto que compartilham fatores gen&#233;ticos&#44; ambientais &#40;disponibilidade de alimentos na resid&#234;ncia&#41; e comportamentais &#40;h&#225;bitos alimentares e de estilo de vida&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">30</span></a></p><p id="par0205" class="elsevierStylePara elsevierViewall">Destaca&#8208;se como aspectos positivos deste estudo a avalia&#231;&#227;o antropom&#233;trica ter sido feita por um &#250;nico pesquisador&#44; o que contribuiu para reduzir os vieses de aferi&#231;&#227;o das medidas&#59; e a amostra ter sido composta exclusivamente por crian&#231;as&#44; o que minimiza as poss&#237;veis influ&#234;ncias hormonais da adolesc&#234;ncia na composi&#231;&#227;o corporal&#46; A an&#225;lise de curva ROC n&#227;o foi feita estratificada pela idade em fun&#231;&#227;o da semelhan&#231;a fisiol&#243;gica entre crian&#231;as de oito e nove anos&#46; Apesar de o DXA ser incapaz de distinguir os tipos de tecido adiposo&#44; a gordura na regi&#227;o androide obtida nesse exame est&#225; fortemente correlacionada ao tecido adiposo visceral em crian&#231;as&#46; Como limita&#231;&#245;es&#44; nota&#8208;se a aus&#234;ncia de valores de refer&#234;ncia para classificar a gordura androide em crian&#231;as&#44; o que nos permitiu usar o percentil 85<span class="elsevierStyleHsp" style=""></span>da amostra de acordo com o sexo&#46; Diante disso&#44; sugerimos estudos que proponham pontos de corte de gordura na regi&#227;o androide e de PP para todas as faixas et&#225;rias infantis&#44; com o prop&#243;sito de se estabelecer um consenso internacional&#46;</p><p id="par0210" class="elsevierStylePara elsevierViewall">Conclu&#237;mos que o PP &#233; uma medida capaz de identificar o excesso de gordura androide em crian&#231;as brasileiras&#46; Os pontos de corte propostos podem ser usados em estudos populacionais&#44; triagens e atendimentos ambulatoriais&#44; desde que sejam validados para o p&#250;blico infantil em que ser&#227;o aplicados&#46; Dessa maneira&#44; o PP pode fazer parte da rotina de avalia&#231;&#227;o do estado de sa&#250;de de crian&#231;as&#44; por ser uma medida simples e de baixo custo&#44; auxilia na identifica&#231;&#227;o precoce do excesso de adiposidade central&#46;</p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Financiamento</span><p id="par0215" class="elsevierStylePara elsevierViewall">Conselho Nacional de Desenvolvimento Cient&#237;fico e Tecnol&#243;gico &#40;CNPq&#41; &#40;processo&#58; 478910&#47;2013&#8208;4&#41;&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Conflitos de interesse</span><p id="par0220" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
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            3 => "Nutritional assessment"
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            1 => "Antropometria"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To evaluate the ability of neck circumference to identify excess android fat and to propose cutoff points for Brazilian children&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">This was a cross&#8208;sectional study with 376 children aged 8 and 9 years enrolled in public and private schools in the urban area of the municipality of Vi&#231;osa&#44; Minas Gerais&#46; A semi&#8208;structured questionnaire containing sociodemographic and lifestyle information was applied&#46; The following were collected&#58; neck circumference&#44; weight&#44; and height for the calculation of body mass index&#46; The percentage of fat in the android region was determined by dual energy X&#8208;ray absorptiometry&#46; Linear regression analysis was used to evaluate the association between neck circumference and android fat&#44; adopting a significance level of 5&#37;&#46; Receiver operating characteristic curves were used to evaluate the capacity of neck circumference to determine the excess android fat&#44; as well as to estimate the cutoff points of neck circumference according to gender&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Multiple linear regression showed an association between neck circumference and android fat &#40;<span class="elsevierStyleItalic">&#946;</span>&#58; 2&#46;94&#44; 95&#37; CI&#58; 2&#46;41&#44; 3&#46;47&#41;&#46; Neck circumference was able to identify excess android fat in girls &#40;AUC&#58; 0&#46;909&#44; 95&#37; CI&#58; 0&#46;999&#44; 0&#46;945&#41; and boys &#40;AUC&#58; 0&#46;938&#44; 95&#37; CI&#58; 0&#46;892&#44; 0&#46;968&#41;&#46; The proposed cutoff points showed satisfactory sensitivity&#44; specificity&#44; and predictive values&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Neck circumference is capable of identifying excess android fat in children and can be used in clinical practice and in population studies to determine central adiposity&#46; The proposed cutoff points were satisfactory&#44; but should be validated for other populations&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Avaliar a capacidade do per&#237;metro do pesco&#231;o em identificar o excesso de gordura androide e propor pontos de corte para crian&#231;as brasileiras&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudo transversal com 376 crian&#231;as de oito e nove anos&#44; matriculadas em escolas p&#250;blicas e privadas da &#225;rea urbana de Vi&#231;osa&#44; Minas Gerais&#46; Foi aplicado um question&#225;rio semiestruturado com informa&#231;&#245;es sociodemogr&#225;ficas e de estilo de vida&#46; Foram coletados&#58; per&#237;metro do pesco&#231;o&#44; peso e estatura para o c&#225;lculo do &#237;ndice de massa corporal&#46; O percentual de gordura na regi&#227;o androide foi determinado pela absorciometria de raios X de dupla energia&#46; A an&#225;lise de regress&#227;o linear foi utilizada para avaliar a associa&#231;&#227;o entre o per&#237;metro do pesco&#231;o e a gordura androide&#44; adotando-se o n&#237;vel de signific&#226;ncia de 5&#37;&#46; Por meio das curvas <span class="elsevierStyleItalic">Receiver Operating Characteristic</span> avaliou&#8208;se a capacidade do per&#237;metro do pesco&#231;o de determinar o excesso de gordura androide&#44; bem como estimaram&#8208;se os pontos de corte de per&#237;metro do pesco&#231;o segundo o sexo&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">A regress&#227;o linear m&#250;ltipla demonstrou associa&#231;&#227;o entre o per&#237;metro do pesco&#231;o e a gordura androide &#40;&#946;&#58; 2&#44;94&#59; IC95&#37;&#58; 2&#44;41&#59; 3&#44;47&#41;&#46; O per&#237;metro do pesco&#231;o foi capaz de identificar o excesso de gordura androide em meninas &#40;AUC&#58; 0&#44;909&#59; IC95&#37;&#58; 0&#44;859&#59; 0&#44;945&#41; e meninos &#40;AUC&#58; 0&#44;938&#59; IC95&#37;&#58; 0&#44;892&#59; 0&#44;968&#41;&#46; Os pontos de corte propostos tiveram valores de sensibilidade&#44; especificidade e preditivos satisfat&#243;rios&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#245;es</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">O per&#237;metro do pesco&#231;o &#233; uma medida capaz de identificar o excesso de gordura androide em crian&#231;as&#44; pode ser usado na pr&#225;tica cl&#237;nica e em estudos populacionais para determinar a adiposidade central&#46; Os pontos de corte propostos foram satisfat&#243;rios&#44; entretanto devem ser validados para outras popula&#231;&#245;es&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0025">Como citar este artigo&#58; Filgueiras MS&#44; Albuquerque FM&#44; Castro AP&#44; Rocha NP&#44; Milagres LC&#44; Novaes JF&#46; Neck circumference cutoff points to identify excess android fat&#46; J Pediatr &#40;Rio J&#41;&#46; 2020&#59;96&#58;356&#8211;63&#46;</p>"
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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">&#193;reas abaixo da curva <span class="elsevierStyleItalic">Receiver Operating Characteristic</span> &#40;ROC&#41; e pontos de corte do per&#237;metro do pesco&#231;o com melhores valores de sensibilidade&#44; especificidade e valores preditivos para excesso de gordura androide&#44; de acordo com o sexo&#46; Vi&#231;osa&#44; MG&#44; 2015&#46;</p> <p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">AUC&#44; <span class="elsevierStyleItalic">area under the curve</span>&#59; IC95&#37;&#44; intervalo de confian&#231;a de 95&#37;&#59; S&#44; sensibilidade&#59; E&#44; especificidade&#59; VPP&#44; valor preditivo positivo&#59; VPN&#44; valor preditivo negativo&#46;</p>"
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>9 anos&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">194 &#40;51&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">16&#46;30 &#40;7&#44;8&#59; 27&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;101&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>P&#250;blica&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">266 &#40;70&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">19&#44;3 &#40;8&#44;7&#59; 27&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;018<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="4" align="left" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; R&#36;500&#44;00&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">191 &#40;50&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;4 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">17&#44;0 &#40;7&#44;3&#59; 27&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>R&#36;500&#44;00&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">185 &#40;49&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;1 &#40;2&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">12&#44;8 &#40;7&#44;1&#59; 24&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;085&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">0&#44;115&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Tempo de tela&#47;dia</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#62; 2 horas&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">178 &#40;47&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">27&#44;3 &#40;26&#44;0&#59; 28&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">15&#44;5 &#40;7&#44;3&#59; 27&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8804; 2 horas&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">198 &#40;52&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">27&#44;0 &#40;25&#44;7&#59; 28&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;119&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;377&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Excesso de peso</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sim&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">123 &#40;32&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">29&#44;2 &#40;1&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">31&#44;3 &#40;9&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>N&#227;o&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">253 &#40;67&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">26&#44;3 &#40;1&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">11&#44;1 &#40;6&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Per&#237;metro do pesco&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Aumentado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">76 &#40;20&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">29&#44;9 &#40;29&#44;0&#59; 31&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">32&#44;7 &#40;25&#44;3&#59; 39&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">300 &#40;79&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">26&#44;5 &#40;25&#44;5&#59; 27&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">10&#44;5 &#40;6&#44;2&#59; 19&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Gordura androide</span><a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; p85&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">73 &#40;19&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">29&#44;5 &#40;28&#44;5&#59; 30&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">35&#44;9 &#40;32&#44;2&#59; 43&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>p85&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">303 &#40;80&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">26&#44;5 &#40;25&#44;5&#59; 27&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">10&#44;5 &#40;6&#44;3&#59; 18&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Excesso de peso materno</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sim&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">168 &#40;57&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;8 &#40;2&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">18&#44;3 &#40;8&#44;4&#59; 30&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>N&#227;o&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">125 &#40;42&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">26&#44;5 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">11&#44;0 &#40;6&#44;2&#59; 19&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Colesterol total</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; 170 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">86 &#40;22&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;5 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">20&#44;5 &#40;7&#44;5&#59; 29&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>170 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">289 &#40;77&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;2 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;8 &#40;7&#44;1&#59; 24&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;278&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;011<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">HDL&#8208;c</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8804; 45 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">131 &#40;34&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;6 &#40;2&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">18&#44;4 &#40;8&#44;0&#59; 32&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#62; 45 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">244 &#40;65&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;1 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;9 &#40;6&#44;9&#59; 23&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;006<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;005<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">LDL&#8208;c</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; 110 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">58 &#40;15&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">27&#44;7 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">22&#44;0 &#40;12&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>110 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">316 &#40;84&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;2 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#44;8 &#40;12&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;064&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;003<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Triglicer&#237;deo</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; 75 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">176 &#40;46&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;7 &#40;2&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">19&#44;9 &#40;8&#44;2&#59; 30&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>75 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">199 &#40;53&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">26&#44;9 &#40;1&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#44;6 &#40;6&#44;5&#59; 19&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
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Neck circumference cutoff points to identify excess android fat
Pontos de corte do perímetro do pescoço para identificar o excesso de gordura androide
Mariana De Santis Filgueiras
Autor para correspondência
mariana.filgueiras@ufv.br

Autor para correspondência.
, Fernanda Martins de Albuquerque, Ana Paula Pereira Castro, Naruna Pereira Rocha, Luana Cupertino Milagres, Juliana Farias de Novaes
Universidade Federal de Viçosa (UFV), Departamento de Nutrição e Saúde, Viçosa, MG, Brasil
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visto que exerce um papel fundamental no desenvolvimento do risco cardiometab&#243;lico&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Existem diferentes t&#233;cnicas para avaliar a adiposidade corporal&#44; a absorciometria de raios X de dupla energia &#40;DXA&#41; &#233; considerada um m&#233;todo refer&#234;ncia para avaliar a adiposidade central em crian&#231;as de todas as idades&#44; pois estima a quantidade de gordura na regi&#227;o androide&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">4</span></a> No entanto&#44; sua aplica&#231;&#227;o em estudos epidemiol&#243;gicos e na pr&#225;tica cl&#237;nica tamb&#233;m &#233; limitada por apresentar custo elevado e execu&#231;&#227;o complexa&#44; s&#227;o necess&#225;rios m&#233;todos simples e menos dispendiosos&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Nesse aspecto&#44; o per&#237;metro do pesco&#231;o &#40;PP&#41; tem sido proposto como uma ferramenta &#250;til para identificar indiv&#237;duos jovens com excesso de peso e risco cardiometab&#243;lico por ser um m&#233;todo simples&#44; de baixo custo e ter uma menor varia&#231;&#227;o ao longo do dia comparado ao per&#237;metro da cintura&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">5</span></a> No entanto&#44; at&#233; o momento&#44; n&#227;o foram encontrados estudos na literatura que avaliaram a associa&#231;&#227;o e a capacidade do PP de identificar o excesso de adiposidade central estimada por um m&#233;todo refer&#234;ncia&#44; como a gordura na regi&#227;o androide determinada pelo DXA&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">A aus&#234;ncia da defini&#231;&#227;o de pontos de corte espec&#237;ficos de PP para crian&#231;as brasileiras pode ser uma limita&#231;&#227;o para seu uso rotineiro&#46; Na literatura&#44; segundo o nosso conhecimento&#44; encontra&#8208;se apenas um estudo de delineamento transversal com adolescentes brasileiros matriculados em escolas p&#250;blicas do munic&#237;pio de S&#227;o Paulo&#8208;SP que prop&#244;s pontos de corte de PP para identificar sobrepeso e obesidade&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">6</span></a> Diante disso&#44; s&#227;o escassos os estudos com essa abordagem em idades mais precoces&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Assim&#44; o objetivo deste estudo foi&#58; 1&#41; avaliar a capacidade do PP de identificar o excesso de gordura androide&#59; 2&#41; propor pontos de corte de PP para determinar o excesso de gordura androide em crian&#231;as brasileiras&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">M&#233;todos</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Popula&#231;&#227;o e delineamento do estudo</span><p id="par0035" class="elsevierStylePara elsevierViewall">Estudo transversal feito com amostra representativa de crian&#231;as de oito e nove anos&#44; 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o munic&#237;pio contava com 17 escolas p&#250;blicas e sete particulares na &#225;rea urbana que atendiam crian&#231;as de oito e nove anos&#44; total de 1&#46;464 crian&#231;as matriculadas&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">C&#225;lculo amostral e processo de amostragem</span><p id="par0045" class="elsevierStylePara elsevierViewall">O c&#225;lculo amostral foi feito no <span class="elsevierStyleItalic">software</span> Epi Info &#40;vers&#227;o 7&#46;2&#59; Atlanta&#44; GA&#41;&#44; considerando o n&#250;mero total de estudantes de oito e nove anos em 2015 &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;464&#41;&#44; preval&#234;ncia de 10&#44;7&#37; de obesidade&#44;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">9</span></a> erro tolerado de 3&#37;&#44; n&#237;vel de confian&#231;a de 95&#37; e acr&#233;scimo de 20&#37; para cobertura de perdas&#44; total de 384 crian&#231;as a serem estudadas&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">As crian&#231;as foram selecionadas por amostragem aleat&#243;ria estratificada&#44; a amostra de cada escola atingiu a proporcionalidade dos alunos matriculados por idade e sexo&#46; A sele&#231;&#227;o de crian&#231;as foi feita por sorteio aleat&#243;rio simples at&#233; que o n&#250;mero necess&#225;rio para cada escola fosse alcan&#231;ado&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Ap&#243;s a sele&#231;&#227;o&#44; fez&#8208;se contato telef&#244;nico com os respons&#225;veis pelas crian&#231;as&#44; as quais foram convidadas a participar do estudo&#46; Foram explicados os objetivos e a metodologia do estudo e foi agendado o primeiro encontro&#44; no qual&#44; ap&#243;s explica&#231;&#227;o de cada etapa aos respons&#225;veis&#44; aqueles que concordaram em participar assinaram o Termo de Consentimento Livre e Esclarecido &#40;TCLE&#41;&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">N&#227;o foram inclu&#237;das crian&#231;as que apresentassem algum problema de sa&#250;de que alterasse o estado nutricional ou a composi&#231;&#227;o corporal &#40;defici&#234;ncias f&#237;sicas&#44; 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socioecon&#244;micos e de estilo de vida</span><p id="par0070" class="elsevierStylePara elsevierViewall">Foi aplicado um question&#225;rio semiestruturado com informa&#231;&#245;es socioecon&#244;micas e demogr&#225;ficas&#44; como idade&#44; sexo&#44; tipo de escola &#40;p&#250;blica ou privada&#41; e renda <span class="elsevierStyleItalic">per capita</span> &#40;categorizada de acordo com a mediana da amostra total&#44; equivalente a R&#36; 500&#44;00&#41;&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Um question&#225;rio sobre estilo de vida foi aplicado para estimar o tempo de tela em horas por dia &#40;tempo gasto sentado por longos per&#237;odos na frente da televis&#227;o&#44; videogame ou computador&#41;&#46; O comportamento sedent&#225;rio foi classificado como tempo de tela maior do que duas horas&#47;dia&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">10</span></a></p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Antropometria e composi&#231;&#227;o corporal</span><p id="par0080" class="elsevierStylePara elsevierViewall">A coleta de dados foi feita em ambiente apropriado por um membro da equipe treinado&#44; com os volunt&#225;rios sem cal&#231;ados e com roupas leves&#46; O peso foi aferido em balan&#231;a digital eletr&#244;nica&#44; com capacidade de 150<span class="elsevierStyleHsp" style=""></span>kg e precis&#227;o de 0&#44;1<span class="elsevierStyleHsp" style=""></span>kg &#40;<span class="elsevierStyleItalic">Tanita</span>&#174; Modelo Ironman BC 553&#44; Tanita Corporation of America Inc&#46;&#44; Artlington Heights&#44; USA&#41; e a estatura foi determinada com um estadi&#244;metro&#44; dividido em cent&#237;metros e subdividido em mil&#237;metros &#40;<span class="elsevierStyleItalic">Alturexata</span>&#174;&#44; Belo Horizonte&#44; Brasil&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Com os dados de peso e estatura obtidos&#44; foi calculado o &#237;ndice de massa corporal &#40;IMC&#41; e para a classifica&#231;&#227;o do estado nutricional das crian&#231;as&#44; foram usados os pontos de corte de IMC por idade &#40;IMC&#47;I&#41; em escore&#8208;z&#44; estabelecidos pela Organiza&#231;&#227;o Mundial da Sa&#250;de&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">11</span></a> Para avalia&#231;&#227;o do estado nutricional das m&#227;es&#44; foram adotados os crit&#233;rios para classifica&#231;&#227;o do IMC preconizados pela Organiza&#231;&#227;o Mundial de Sa&#250;de&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">12</span></a> Crian&#231;as e m&#227;es com sobrepeso e obesidade foram agrupadas em excesso de peso&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">O PP foi avaliado com a crian&#231;a em p&#233;&#44; ereta com a cabe&#231;a&#44; no plano horizontal de Frankfurt&#44; com uma fita m&#233;trica inextens&#237;vel &#40;<span class="elsevierStyleItalic">TBW</span>&#174;&#44; S&#227;o Paulo&#44; Brasil&#41;&#44; exatamente abaixo da proemin&#234;ncia lar&#237;ngea no pesco&#231;o&#44; perpendicularmente ao maior eixo do pesco&#231;o&#46; Foi exercida press&#227;o m&#237;nima&#44; de forma que permitisse o contato completo da fita com a pele&#46; A aferi&#231;&#227;o foi feita em duplicata&#44; foi considerada a m&#233;dia das duas medidas&#46; Para classifica&#231;&#227;o&#44; foram usados os pontos de corte obtidos nas curvas <span class="elsevierStyleItalic">Receiver Operating Characteristic</span> &#40;ROC&#41; com melhores valores de sensibilidade&#44; especificidade e valores preditivos para excesso gordura androide&#44; de acordo com o sexo&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">O percentual de gordura na regi&#227;o androide foi determinado pela absorciometria de raios X de dupla energia &#40;DXA&#41; &#40;Lunar Prodigy Advance&#59; GE Medical Systems Lunar&#44; Milwaukee&#44; WI&#44; USA&#41;&#44; usou&#8208;se o <span class="elsevierStyleItalic">software</span> do pr&#243;prio equipamento para an&#225;lise de composi&#231;&#227;o corporal&#46; A gordura androide foi identificada na regi&#227;o entre as costelas e a pelve&#44; a demarca&#231;&#227;o superior foi feita a 20&#37; da dist&#226;ncia da crista il&#237;aca e do pesco&#231;o e a demarca&#231;&#227;o inferior feita acima da pelve&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">4</span></a> N&#227;o foram encontrados na literatura pontos de corte para o diagn&#243;stico de gordura androide elevada em crian&#231;as&#46; Por isso&#44; considerou&#8208;se como valores aumentados o percentil 85<span class="elsevierStyleHsp" style=""></span>da amostra de acordo com o sexo&#44; que corresponderam aos valores de 34&#44;0&#37; e 28&#44;9&#37; para meninas e meninos&#44; respectivamente&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Avalia&#231;&#227;o bioqu&#237;mica e de press&#227;o arterial</span><p id="par0100" class="elsevierStylePara elsevierViewall">A coleta de sangue foi feita ap&#243;s jejum de 12 horas no Laborat&#243;rio de An&#225;lises Cl&#237;nicas da Divis&#227;o de Sa&#250;de da Universidade Federal de Vi&#231;osa &#40;UFV&#41;&#46; As amostras foram coletadas por pun&#231;&#227;o venosa em tubo soro&#44; foram centrifugadas por 15 minutos a 3&#46;500<span class="elsevierStyleHsp" style=""></span>rpm e depois separadas em <span class="elsevierStyleItalic">eppendorfs</span> de 1&#44;5<span class="elsevierStyleHsp" style=""></span>mL e armazenadas em <span class="elsevierStyleItalic">ultrafreezer</span> a &#8208;80<span class="elsevierStyleHsp" style=""></span>&#176;C&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">O perfil lip&#237;dico &#40;colesterol total&#44; lipoprote&#237;na de alta densidade &#8208; HDL&#8208;c&#44; lipoprote&#237;na de baixa densidade &#8208; LDL&#8208;c e triglicer&#237;deo&#41; e a glicemia de jejum foram determinados pelo m&#233;todo enzim&#225;tico colorim&#233;trico&#44; usou&#8208;se kit comercial Bioclin&#174; &#40;Belo Horizonte&#44; MG&#44; Brasil&#41; e foram dosados em equipamento analisador autom&#225;tico &#40;BS&#8208;200 Mindray&#174;&#44; Nanshan&#44; China&#41; no Laborat&#243;rio de An&#225;lises Cl&#237;nicas &#40;LAC&#41; do Departamento de Nutri&#231;&#227;o e Sa&#250;de da UFV&#46; A classifica&#231;&#227;o dos componentes do perfil lip&#237;dico foi feita de acordo com a Atualiza&#231;&#227;o da Diretriz Brasileira de Dislipidemias e Preven&#231;&#227;o da Aterosclerose&#46;<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">13</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">A insulina de jejum foi determinada pelo m&#233;todo de imunoensaio por quimioluminesc&#234;ncia no laborat&#243;rio Diagn&#243;sticos do Brasil&#44; foi quantificada pelo teste&#160;Elecsys Insulin&#174; com limite de detec&#231;&#227;o de 0&#44;200&#8208;1&#46;000<span class="elsevierStyleHsp" style=""></span>&#956;U&#47;mL&#46; Para a classifica&#231;&#227;o da resist&#234;ncia &#224; insulina&#44; foi usado o valor de HOMA&#8208;IR maior ou igual a 3&#44;16&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">14</span></a></p><p id="par0115" class="elsevierStylePara elsevierViewall">Para aferir a press&#227;o arterial usou&#8208;se um equipamento eletr&#244;nico digital no bra&#231;o com infla&#231;&#227;o e defla&#231;&#227;o autom&#225;tica do ar&#44; o tamanho do manguito foi apropriado para o paciente&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a> Para avaliar a press&#227;o arterial consideraram&#8208;se sexo&#44; idade e percentil de estatura&#44; tamb&#233;m de acordo com a classifica&#231;&#227;o preconizada pela Sociedade Brasileira de Cardiologia&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a></p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">An&#225;lises estat&#237;sticas</span><p id="par0120" class="elsevierStylePara elsevierViewall">Foram feitas no <span class="elsevierStyleItalic">software Statistical Package for the Social Sciences for</span><span class="elsevierStyleItalic">Windows</span>&#44; vers&#227;o 23&#46;0 &#40;SPSS Inc&#46; Chicago&#44; USA&#41;&#46; O teste de normalidade de Kolmogorov&#8208;Smirnov foi usado para determinar se as vari&#225;veis quantitativas cont&#237;nuas apresentavam distribui&#231;&#227;o normal&#46; O n&#237;vel de signific&#226;ncia adotado para todos os testes de hip&#243;teses foi de 5&#37;&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Foram feitas an&#225;lises descritivas dos dados&#44; por meio de frequ&#234;ncias relativas&#44; m&#233;dias &#40;desvio&#8208;padr&#227;o&#41; ou medianas &#40;intervalo interquartil&#41;&#46; Para compara&#231;&#227;o de m&#233;dias ou medianas entre duas amostras independentes foram feitos os testes <span class="elsevierStyleItalic">t</span> de Student ou de Mann&#8208;Whitney&#44; respectivamente&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">A associa&#231;&#227;o entre o PP &#40;vari&#225;vel independente&#41; e a gordura androide &#40;vari&#225;vel dependente&#41; foi avaliada pela regress&#227;o linear m&#250;ltipla&#46; As vari&#225;veis de ajuste que compuseram o modelo final foram&#58; sexo&#44; tipo de escola &#40;p&#250;blica ou privada&#41;&#44; colesterol total&#44; HDL&#8208;c&#44; HOMA&#8208;IR e IMC materno&#46; O modelo final foi avaliado de acordo com os pressupostos da linearidade&#44; homocedasticidade&#44; normalidade&#44; independ&#234;ncia&#44; multicolinearidade e res&#237;duos padronizados&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">As curvas <span class="elsevierStyleItalic">Receiver Operating Characteristic</span> &#40;ROC&#41; determinaram a capacidade do PP de identificar o excesso de gordura androide&#46; Al&#233;m disso&#44; foram estimados os pontos de corte de PP com melhores valores de sensibilidade &#40;S&#41; e especificidade &#40;E&#41;&#44; valores preditivos positivo &#40;VPP&#41; e negativo &#40;VPN&#41;&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Aspectos &#233;ticos</span><p id="par0140" class="elsevierStylePara elsevierViewall">Este estudo foi feito de acordo com as diretrizes estabelecidas na Declara&#231;&#227;o de Helsinque e aprovado pelo Comit&#234; de &#201;tica em Pesquisa com Seres Humanos da Universidade Federal de Vi&#231;osa &#40;parecer n&#176; 663&#46;171&#47;2014&#41;&#46; O mesmo tamb&#233;m foi aprovado pela Secretaria Municipal de Educa&#231;&#227;o&#44; Superintend&#234;ncia Regional de Ensino e dire&#231;&#227;o das escolas&#46;</p></span></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Resultados</span><p id="par0145" class="elsevierStylePara elsevierViewall">A amostra final foi constitu&#237;da por 376 crian&#231;as&#44; houve perda de 2&#44;1&#37; dos participantes por n&#227;o completarem todas as etapas da pesquisa &#40;n&#227;o fizeram a coleta de sangue para exames bioqu&#237;micos&#41;&#46; A partir dos pontos de cortes propostos nas curvas ROC&#44; observou&#8208;se que 20&#44;2&#37; &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>76&#41; das crian&#231;as apresentaram PP elevado &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0150" class="elsevierStylePara elsevierViewall">Na amostra geral&#44; o PP e o percentual de gordura androide apresentaram medianas de 27&#44;0<span class="elsevierStyleHsp" style=""></span>cm e 14&#44;9&#37;&#44; respectivamente&#46; Observaram&#8208;se maiores percentuais de gordura androide em crian&#231;as do sexo feminino&#44; de escolas privadas&#44; com excesso de peso&#44; perfil lip&#237;dico indesejado&#44; resist&#234;ncia &#224; insulina&#44; press&#227;o arterial elevada e excesso de peso materno&#46; Os mesmos resultados foram encontrados para os maiores valores do PP&#44; com exce&#231;&#227;o para o tipo de escola&#44; colesterol total e LDL&#8208;c &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">No modelo final de regress&#227;o linear m&#250;ltipla&#44; observou&#8208;se associa&#231;&#227;o positiva entre o PP e o percentual de gordura androide&#46; O aumento em 1<span class="elsevierStyleHsp" style=""></span>cm no PP esteve associado ao aumento de 2&#44;94&#37; na gordura androide&#44; ao ser ajustado por sexo&#44; tipo de escola&#44; colesterol total&#44; HDL&#8208;c&#44; HOMA&#8208;IR e IMC materno &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabela 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0160" class="elsevierStylePara elsevierViewall">A an&#225;lise na curva ROC demonstrou que o PP foi capaz de identificar o excesso de gordura androide em meninas &#40;AUC&#58; 0&#44;909&#59; IC95&#37;&#58; 0&#44;859&#59; 0&#44;945&#41; e meninos &#40;AUC&#58; 0&#44;938&#59; IC95&#37;&#58; 0&#44;892&#59; 0&#44;968&#41;&#46; Os pontos de corte propostos para o sexo feminino &#40;28&#44;3<span class="elsevierStyleHsp" style=""></span>cm&#41; e masculino &#40;28&#44;6<span class="elsevierStyleHsp" style=""></span>cm&#41; tiveram valores de S &#40;feminino&#58; 76&#44;1&#37;&#59; masculino&#58; 85&#44;2&#37;&#41;&#44; E &#40;feminino&#58; 92&#44;7&#37;&#59; masculino&#58; 87&#44;6&#37;&#41; e valores preditivos &#40;feminino&#58; VPP 76&#44;1&#37;&#44; VPN 92&#44;7&#37;&#59; masculino&#58; VPP 56&#44;4&#37;&#44; VPN 97&#44;1&#37;&#41; satisfat&#243;rios &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Discuss&#227;o</span><p id="par0165" class="elsevierStylePara elsevierViewall">At&#233; o presente momento&#44; este &#233; o primeiro estudo brasileiro feito com amostra representativa de crian&#231;as que demonstrou a capacidade do PP de identificar o excesso de gordura androide&#46; Ademais&#44; o PP apresentou associa&#231;&#227;o direta com a gordura androide&#44; independentemente do sexo&#44; tipo de escola&#44; das concentra&#231;&#245;es s&#233;ricas de colesterol total e HDL&#8208;c&#44; HOMA&#8208;IR e IMC materno&#46; Ressalta&#8208;se que os pontos de corte propostos apresentaram valores de S&#44; E e valores preditivos satisfat&#243;rios&#44; viabilizaram o uso do PP em estudos epidemiol&#243;gicos&#44; triagens do risco cardiometab&#243;lico e atendimentos ambulatoriais&#46;</p><p id="par0170" class="elsevierStylePara elsevierViewall">O uso do PP em adultos &#233; amplamente estudado&#44; observou&#8208;se sua associa&#231;&#227;o direta com o tecido adiposo visceral e o HOMA&#8208;IR em obesos&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">16</span></a> Al&#233;m disso&#44; um estudo de base populacional com adultos brasileiros demonstrou que o PP pode ser usado para identificar s&#237;ndrome metab&#243;lica e resist&#234;ncia &#224; insulina&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">17</span></a></p><p id="par0175" class="elsevierStylePara elsevierViewall">Nesse sentido&#44; o uso do PP na popula&#231;&#227;o pedi&#225;trica se torna importante&#44; a maioria dos estudos com esse p&#250;blico o comparou com m&#233;todos de estimativa de adiposidade duplamente indiretos&#44; como IMC&#44;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> per&#237;metro da cintura<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> e rela&#231;&#227;o cintura&#8208;estatura&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">20</span></a> Em indiv&#237;duos de nove a 13 anos da Gr&#233;cia&#44; o PP esteve associado diretamente &#224;s concentra&#231;&#245;es s&#233;ricas de triglicer&#237;deo e insulina&#44; HOMA&#8208;IR e press&#227;o arterial&#59; e inversamente &#224; concentra&#231;&#227;o s&#233;rica de HDL&#8208;c&#44; <span class="elsevierStyleItalic">quantitative insulin sensitivity check index</span> &#40;QUICKI&#41; e raz&#227;o glicose&#8208;insulina de jejum &#40;FGIR&#41;&#46; O mesmo estudo demonstrou que outras medidas antropom&#233;tricas usadas em crian&#231;as e adolescentes&#44; como escore&#8208;z de IMC&#44; per&#237;metro da cintura e do quadril&#44; rela&#231;&#227;o cintura&#8208;estatura e rela&#231;&#227;o cintura&#8208;quadril&#44; apresentaram associa&#231;&#245;es com os marcadores de risco cardiometab&#243;lico semelhantes ao PP&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">21</span></a></p><p id="par0180" class="elsevierStylePara elsevierViewall">O PP &#233; considerado uma op&#231;&#227;o para identificar adiposidade central por apresentar algumas vantagens em rela&#231;&#227;o ao per&#237;metro da cintura&#44; tais como&#58; boa concord&#226;ncia inter e intraobservador&#59; n&#227;o &#233; influenciado pelo hor&#225;rio de mensura&#231;&#227;o &#40;per&#237;odo pr&#233;&#8208;prandial e p&#243;s&#8208;prandial&#41;&#59; maior facilidade para mensurar&#44; pois n&#227;o requer que o examinado esteja com o m&#237;nimo de vestu&#225;rios&#44; &#233; assim mais aceit&#225;vel socialmente&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> Entretanto&#44; n&#227;o h&#225; um consenso internacional sobre pontos de corte a serem adotados para o p&#250;blico infantil&#46;</p><p id="par0185" class="elsevierStylePara elsevierViewall">Existem pontos de corte do PP propostos a partir de curvas ROC<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> e de percentis<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">22</span></a> para crian&#231;as e adolescentes de acordo com o sexo e a idade em diferentes localidades&#46; No entanto&#44; a grande maioria &#233; de pontos de corte capazes de determinar o excesso de peso&#47;obesidade pelo IMC&#46;<a class="elsevierStyleCrossRefs" href="#bib0240"><span class="elsevierStyleSup">18&#44;22</span></a> Por isso&#44; o presente estudo prop&#244;s pontos de corte de PP que podem ser usados para identificar o excesso de gordura androide pelo DXA&#44; que &#233; capaz de estimar adiposidade central&#44; &#233; um m&#233;todo considerado refer&#234;ncia&#46;<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">23</span></a></p><p id="par0190" class="elsevierStylePara elsevierViewall">Em estudo transversal com adolescentes brasileiros de Campinas&#8208;SP&#44; os pontos de corte de PP sugeridos para determinar resist&#234;ncia &#224; insulina foram de 32&#44;0 e 30&#44;3<span class="elsevierStyleHsp" style=""></span>cm para meninas e meninos pr&#233;&#8208;p&#250;beres&#44; respectivamente&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> Os pontos de corte propostos em estudo transversal feito por Nafiu et al&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> para identificar o excesso de peso em crian&#231;as americanas de oito e nove anos foram 29&#44;0 e 30&#44;5<span class="elsevierStyleHsp" style=""></span>cm &#40;meninos&#41;&#44; 27&#44;9 e 29&#44;3<span class="elsevierStyleHsp" style=""></span>cm &#40;meninas&#41;&#44; respectivamente&#44; pr&#243;ximos dos valores encontrados no nosso estudo&#46; Diante disso&#44; recomenda&#8208;se a valida&#231;&#227;o dos pontos de corte propostos no presente trabalho para outras popula&#231;&#245;es&#44; com o objetivo de identificar o excesso de adiposidade central e tamb&#233;m outros fatores de risco cardiometab&#243;lico&#46;</p><p id="par0195" class="elsevierStylePara elsevierViewall">S&#227;o de grande relev&#226;ncia estudos que abordam o excesso de adiposidade central no p&#250;blico infantil&#44; visto que as medidas antropom&#233;tricas que estimam adiposidade central apresentaram maior associa&#231;&#227;o com o risco cardiometab&#243;lico&#44; em rela&#231;&#227;o ao IMC em crian&#231;as&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">24</span></a> A gordura na regi&#227;o androide compreende o tecido adiposo visceral&#44; o qual &#233; mais lipol&#237;tico comparado com o das regi&#245;es perif&#233;ricas&#46; Observa&#8208;se maior libera&#231;&#227;o hep&#225;tica de LDL&#8208;c&#44; triglicer&#237;deos e outros &#225;cidos graxos na circula&#231;&#227;o portal&#44; est&#237;mulo da gliconeog&#234;nese hep&#225;tica e inibi&#231;&#227;o da capta&#231;&#227;o hep&#225;tica de insulina&#44; que causam hiperinsulinemia e resist&#234;ncia &#224; insulina&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">25</span></a></p><p id="par0200" class="elsevierStylePara elsevierViewall">Considerando as elevadas preval&#234;ncias de excesso de peso&#44; perfil lip&#237;dico indesejado e comportamento sedent&#225;rio nesta amostra e em outras pesquisas semelhantes&#44;<a class="elsevierStyleCrossRefs" href="#bib0280"><span class="elsevierStyleSup">26&#44;27</span></a> torna&#8208;se necess&#225;rio o diagn&#243;stico precoce do excesso de adiposidade central em crian&#231;as&#46; Sabe&#8208;se que todas essas altera&#231;&#245;es podem permanecer na fase adulta&#44; al&#233;m de estar relacionadas ao processo de aterog&#234;nese e a danos card&#237;acos&#44; que j&#225; podem iniciar na inf&#226;ncia&#46;<a class="elsevierStyleCrossRefs" href="#bib0290"><span class="elsevierStyleSup">28&#44;29</span></a> Ademais&#44; a avalia&#231;&#227;o do estado nutricional materno &#233; importante para identificar o excesso de adiposidade central em crian&#231;as&#44; visto que compartilham fatores gen&#233;ticos&#44; ambientais &#40;disponibilidade de alimentos na resid&#234;ncia&#41; e comportamentais &#40;h&#225;bitos alimentares e de estilo de vida&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">30</span></a></p><p id="par0205" class="elsevierStylePara elsevierViewall">Destaca&#8208;se como aspectos positivos deste estudo a avalia&#231;&#227;o antropom&#233;trica ter sido feita por um &#250;nico pesquisador&#44; o que contribuiu para reduzir os vieses de aferi&#231;&#227;o das medidas&#59; e a amostra ter sido composta exclusivamente por crian&#231;as&#44; o que minimiza as poss&#237;veis influ&#234;ncias hormonais da adolesc&#234;ncia na composi&#231;&#227;o corporal&#46; A an&#225;lise de curva ROC n&#227;o foi feita estratificada pela idade em fun&#231;&#227;o da semelhan&#231;a fisiol&#243;gica entre crian&#231;as de oito e nove anos&#46; Apesar de o DXA ser incapaz de distinguir os tipos de tecido adiposo&#44; a gordura na regi&#227;o androide obtida nesse exame est&#225; fortemente correlacionada ao tecido adiposo visceral em crian&#231;as&#46; Como limita&#231;&#245;es&#44; nota&#8208;se a aus&#234;ncia de valores de refer&#234;ncia para classificar a gordura androide em crian&#231;as&#44; o que nos permitiu usar o percentil 85<span class="elsevierStyleHsp" style=""></span>da amostra de acordo com o sexo&#46; Diante disso&#44; sugerimos estudos que proponham pontos de corte de gordura na regi&#227;o androide e de PP para todas as faixas et&#225;rias infantis&#44; com o prop&#243;sito de se estabelecer um consenso internacional&#46;</p><p id="par0210" class="elsevierStylePara elsevierViewall">Conclu&#237;mos que o PP &#233; uma medida capaz de identificar o excesso de gordura androide em crian&#231;as brasileiras&#46; Os pontos de corte propostos podem ser usados em estudos populacionais&#44; triagens e atendimentos ambulatoriais&#44; desde que sejam validados para o p&#250;blico infantil em que ser&#227;o aplicados&#46; Dessa maneira&#44; o PP pode fazer parte da rotina de avalia&#231;&#227;o do estado de sa&#250;de de crian&#231;as&#44; por ser uma medida simples e de baixo custo&#44; auxilia na identifica&#231;&#227;o precoce do excesso de adiposidade central&#46;</p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Financiamento</span><p id="par0215" class="elsevierStylePara elsevierViewall">Conselho Nacional de Desenvolvimento Cient&#237;fico e Tecnol&#243;gico &#40;CNPq&#41; &#40;processo&#58; 478910&#47;2013&#8208;4&#41;&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Conflitos de interesse</span><p id="par0220" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
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            3 => "Nutritional assessment"
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            1 => "Antropometria"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To evaluate the ability of neck circumference to identify excess android fat and to propose cutoff points for Brazilian children&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">This was a cross&#8208;sectional study with 376 children aged 8 and 9 years enrolled in public and private schools in the urban area of the municipality of Vi&#231;osa&#44; Minas Gerais&#46; A semi&#8208;structured questionnaire containing sociodemographic and lifestyle information was applied&#46; The following were collected&#58; neck circumference&#44; weight&#44; and height for the calculation of body mass index&#46; The percentage of fat in the android region was determined by dual energy X&#8208;ray absorptiometry&#46; Linear regression analysis was used to evaluate the association between neck circumference and android fat&#44; adopting a significance level of 5&#37;&#46; Receiver operating characteristic curves were used to evaluate the capacity of neck circumference to determine the excess android fat&#44; as well as to estimate the cutoff points of neck circumference according to gender&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Multiple linear regression showed an association between neck circumference and android fat &#40;<span class="elsevierStyleItalic">&#946;</span>&#58; 2&#46;94&#44; 95&#37; CI&#58; 2&#46;41&#44; 3&#46;47&#41;&#46; Neck circumference was able to identify excess android fat in girls &#40;AUC&#58; 0&#46;909&#44; 95&#37; CI&#58; 0&#46;999&#44; 0&#46;945&#41; and boys &#40;AUC&#58; 0&#46;938&#44; 95&#37; CI&#58; 0&#46;892&#44; 0&#46;968&#41;&#46; The proposed cutoff points showed satisfactory sensitivity&#44; specificity&#44; and predictive values&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Neck circumference is capable of identifying excess android fat in children and can be used in clinical practice and in population studies to determine central adiposity&#46; The proposed cutoff points were satisfactory&#44; but should be validated for other populations&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Avaliar a capacidade do per&#237;metro do pesco&#231;o em identificar o excesso de gordura androide e propor pontos de corte para crian&#231;as brasileiras&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudo transversal com 376 crian&#231;as de oito e nove anos&#44; matriculadas em escolas p&#250;blicas e privadas da &#225;rea urbana de Vi&#231;osa&#44; Minas Gerais&#46; Foi aplicado um question&#225;rio semiestruturado com informa&#231;&#245;es sociodemogr&#225;ficas e de estilo de vida&#46; Foram coletados&#58; per&#237;metro do pesco&#231;o&#44; peso e estatura para o c&#225;lculo do &#237;ndice de massa corporal&#46; O percentual de gordura na regi&#227;o androide foi determinado pela absorciometria de raios X de dupla energia&#46; A an&#225;lise de regress&#227;o linear foi utilizada para avaliar a associa&#231;&#227;o entre o per&#237;metro do pesco&#231;o e a gordura androide&#44; adotando-se o n&#237;vel de signific&#226;ncia de 5&#37;&#46; Por meio das curvas <span class="elsevierStyleItalic">Receiver Operating Characteristic</span> avaliou&#8208;se a capacidade do per&#237;metro do pesco&#231;o de determinar o excesso de gordura androide&#44; bem como estimaram&#8208;se os pontos de corte de per&#237;metro do pesco&#231;o segundo o sexo&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">A regress&#227;o linear m&#250;ltipla demonstrou associa&#231;&#227;o entre o per&#237;metro do pesco&#231;o e a gordura androide &#40;&#946;&#58; 2&#44;94&#59; IC95&#37;&#58; 2&#44;41&#59; 3&#44;47&#41;&#46; O per&#237;metro do pesco&#231;o foi capaz de identificar o excesso de gordura androide em meninas &#40;AUC&#58; 0&#44;909&#59; IC95&#37;&#58; 0&#44;859&#59; 0&#44;945&#41; e meninos &#40;AUC&#58; 0&#44;938&#59; IC95&#37;&#58; 0&#44;892&#59; 0&#44;968&#41;&#46; Os pontos de corte propostos tiveram valores de sensibilidade&#44; especificidade e preditivos satisfat&#243;rios&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#245;es</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">O per&#237;metro do pesco&#231;o &#233; uma medida capaz de identificar o excesso de gordura androide em crian&#231;as&#44; pode ser usado na pr&#225;tica cl&#237;nica e em estudos populacionais para determinar a adiposidade central&#46; Os pontos de corte propostos foram satisfat&#243;rios&#44; entretanto devem ser validados para outras popula&#231;&#245;es&#46;</p></span>"
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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">&#193;reas abaixo da curva <span class="elsevierStyleItalic">Receiver Operating Characteristic</span> &#40;ROC&#41; e pontos de corte do per&#237;metro do pesco&#231;o com melhores valores de sensibilidade&#44; especificidade e valores preditivos para excesso de gordura androide&#44; de acordo com o sexo&#46; Vi&#231;osa&#44; MG&#44; 2015&#46;</p> <p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">AUC&#44; <span class="elsevierStyleItalic">area under the curve</span>&#59; IC95&#37;&#44; intervalo de confian&#231;a de 95&#37;&#59; S&#44; sensibilidade&#59; E&#44; especificidade&#59; VPP&#44; valor preditivo positivo&#59; VPN&#44; valor preditivo negativo&#46;</p>"
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Masculino&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">180 &#40;47&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;4 &#40;26&#44;4&#59; 28&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;7 &#40;5&#44;9&#59; 22&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>8 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">182 &#40;48&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26&#44;6 &#40;25&#44;5&#59; 28&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#44;1 &#40;6&#44;8&#59; 23&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>9 anos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">194 &#40;51&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;5 &#40;26&#44;2&#59; 28&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#46;30 &#40;7&#44;8&#59; 27&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;101&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Tipo de escola</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>P&#250;blica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">266 &#40;70&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;2 &#40;2&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;5 &#40;6&#44;9&#59; 25&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Privada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">110 &#40;29&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;4 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">19&#44;3 &#40;8&#44;7&#59; 27&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;448&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;018<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Renda per capita</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; R&#36;500&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">191 &#40;50&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;4 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&#44;0 &#40;7&#44;3&#59; 27&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>R&#36;500&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">185 &#40;49&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;1 &#40;2&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;8 &#40;7&#44;1&#59; 24&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;085&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;115&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Tempo de tela&#47;dia</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#62; 2 horas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">178 &#40;47&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;3 &#40;26&#44;0&#59; 28&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15&#44;5 &#40;7&#44;3&#59; 27&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8804; 2 horas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">198 &#40;52&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;0 &#40;25&#44;7&#59; 28&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#44;2 &#40;7&#44;1&#59; 25&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;119&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;377&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Excesso de peso</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sim&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">123 &#40;32&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">31&#44;3 &#40;9&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>N&#227;o&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">253 &#40;67&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">26&#44;3 &#40;1&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">11&#44;1 &#40;6&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Per&#237;metro do pesco&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Aumentado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">76 &#40;20&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">29&#44;9 &#40;29&#44;0&#59; 31&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">32&#44;7 &#40;25&#44;3&#59; 39&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">300 &#40;79&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">26&#44;5 &#40;25&#44;5&#59; 27&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">10&#44;5 &#40;6&#44;2&#59; 19&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Gordura androide</span><a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; p85&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">73 &#40;19&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">29&#44;5 &#40;28&#44;5&#59; 30&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">35&#44;9 &#40;32&#44;2&#59; 43&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>p85&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">303 &#40;80&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">26&#44;5 &#40;25&#44;5&#59; 27&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">10&#44;5 &#40;6&#44;3&#59; 18&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8208;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Excesso de peso materno</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sim&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">168 &#40;57&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">27&#44;8 &#40;2&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">18&#44;3 &#40;8&#44;4&#59; 30&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>N&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">125 &#40;42&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">26&#44;5 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">11&#44;0 &#40;6&#44;2&#59; 19&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Colesterol total</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; 170 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">86 &#40;22&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;5 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">20&#44;5 &#40;7&#44;5&#59; 29&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>170 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">289 &#40;77&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">27&#44;2 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;8 &#40;7&#44;1&#59; 24&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">0&#44;278&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;011<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="4" align="left" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8804; 45 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">131 &#40;34&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">27&#44;6 &#40;2&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">18&#44;4 &#40;8&#44;0&#59; 32&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#62; 45 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">244 &#40;65&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">27&#44;1 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;9 &#40;6&#44;9&#59; 23&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;006<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;005<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">LDL&#8208;c</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; 110 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">58 &#40;15&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#44;7 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">22&#44;0 &#40;12&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>110 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">316 &#40;84&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;2 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">16&#44;8 &#40;12&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;064&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;003<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Triglicer&#237;deo</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; 75 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">176 &#40;46&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;7 &#40;2&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">19&#44;9 &#40;8&#44;2&#59; 30&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>75 mg&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">199 &#40;53&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26&#44;9 &#40;1&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#44;6 &#40;6&#44;5&#59; 19&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">HOMA&#8208;IR</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#8805; 3&#44;16&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9 &#40;2&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">30&#44;1 &#40;1&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>3&#44;16&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">362 &#40;97&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">27&#44;2 &#40;1&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">17&#44;3 &#40;11&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>p&#8208;valor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Press&#227;o arterial</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Aumentada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">25 &#40;6&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">29&#44;1 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Worldwide trends in body&#8208;mass index&#44; underweight&#44; overweight&#44; and obesity from 1975 to 2016&#58; a pooled analysis of 2416 population&#8208;based measurement studies in 128&#46; 9 million children&#44; adolescents&#44; and adults"
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                      "doi" => "10.1016/S0140-6736(17)32129-3"
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                0 => array:2 [
                  "contribucion" => array:1 [
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                      "titulo" => "Pesquisa de Or&#231;amentos Familiares 2008&#8211;2009&#46; Antropometria e estado nutricional de crian&#231;as&#44; adolescentes e adultos no Brasil"
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                            0 => "Instituto Brasileiro de Geografia e Estat&#237;stica &#40;IBGE&#41;"
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                        "editorialLocalizacion" => "Rio de Janeiro"
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                      "titulo" => "Insulin resistance and obesity in childhood"
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                          "autores" => array:2 [
                            0 => "F&#46; Chiarelli"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dual&#8208;energy X&#8208;ray absorptiometry for total body and regional bone&#8208;mineral and soft&#8208;tissue composition"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;B&#46; Mazess"
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                            2 => "J&#46; Hanson"
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                        ]
                      ]
                    ]
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                    0 => array:2 [
                      "doi" => "10.1093/ajcn/51.6.1106"
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                        "tituloSerie" => "Am J Clin Nutr"
                        "fecha" => "1990"
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                            0 => "O&#46;O&#46; Nafiu"
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ISSN: 22555536
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