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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introdu&#231;&#227;o</span><p id="par0005" class="elsevierStylePara elsevierViewall">O per&#237;odo neonatal &#233; uma &#233;poca de adapta&#231;&#227;o&#44; na qual as rea&#231;&#245;es patol&#243;gicas e fisiol&#243;gicas muitas vezes se confundem&#44; as altera&#231;&#245;es cut&#226;neas s&#227;o comuns nesse per&#237;odo&#46;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">1&#8211;4</span></a> Alguns autores relataram que 57 a 99&#44;4&#37; dos rec&#233;m&#8208;nascidos &#40;RN&#41; apresentam alguma altera&#231;&#227;o na pele e 84&#37; t&#234;m mais de um achado dermatol&#243;gico&#46;<a class="elsevierStyleCrossRefs" href="#bib0140"><span class="elsevierStyleSup">3&#44;5&#44;6</span></a> A frequ&#234;ncia dessas manifesta&#231;&#245;es difere entre os distintos grupos &#233;tnicos&#46;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">1&#44;3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">A maioria s&#227;o les&#245;es transit&#243;rias e pr&#243;prias do per&#237;odo neonatal&#44; como o lanugo&#44; a hiperplasia de gl&#226;ndulas seb&#225;ceas e a descama&#231;&#227;o da cut&#226;nea&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">5</span></a> As marcas de nascimento&#44; tais como a mancha salm&#227;o e a melanocitose d&#233;rmica&#44; geralmente s&#227;o identificadas logo ap&#243;s o nascimento&#44; em grande parte s&#227;o decorrentes da matura&#231;&#227;o da pele do neonato ou do aprofundamento do pigmento cut&#226;neo ao longo do tempo&#46;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">2</span></a> As pustuloses benignas neonatais&#44; que costumam ser observadas nas primeiras semanas de vida&#44; incluem o eritema t&#243;xico neonatal &#40;ETN&#41;&#44; a melanose pustulosa transit&#243;ria neonatal &#40;MPTN&#41; e a pustulose cef&#225;lica benigna &#40;PCB&#41;&#46;<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">7&#8211;9</span></a> Quanto &#224;s anomalias do desenvolvimento que ocorrem na pele e podem ser observadas no per&#237;odo neonatal&#44; as mais frequentes s&#227;o&#58; aplasia c&#250;tis&#44; f&#237;stulas e cistos&#44; mamilo extranumer&#225;rio e p&#243;lipo anexial perimamilar&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">10</span></a> Ademais&#44; a introdu&#231;&#227;o de novas tecnologias e abordagens no cuidado com o RN&#44; somada &#224; fragilidade da pele nessa faixa et&#225;ria&#44; faz com que as complica&#231;&#245;es cut&#226;neas sejam observadas com maior frequ&#234;ncia&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">11</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Estudos para estimar a frequ&#234;ncia das altera&#231;&#245;es cut&#226;neas em neonatos foram conduzidos em diversos pa&#237;ses&#44; por&#233;m no Brasil o assunto foi pouco estudado&#46; Com este estudo queremos aumentar o conhecimento m&#233;dico sobre as caracter&#237;sticas cut&#226;neas do neonato&#44; bem como associ&#225;&#8208;lo com fatores neonatais&#44; gestacionais e sazonalidade&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Material e m&#233;todos</span><p id="par0020" class="elsevierStylePara elsevierViewall">Estudo prospectivo e multic&#234;ntrico&#44; feito nas maternidades de Porto Alegre&#58; Hospital de Cl&#237;nicas de Porto Alegre &#40;HCPA&#41;&#44; Complexo Hospitalar Santa Casa de Porto Alegre e Hospital F&#234;mina &#8211; Grupo Hospitalar Concei&#231;&#227;o &#40;GHC&#41;&#44; de julho de 2011 a junho de 2012&#46; A aleatoriedade dos RN selecionados para o estudo foi estabelecida pela data de nascimento&#58; o programa <span class="elsevierStyleItalic">Pepi4&#8208;Random &#8211; Procedures using Random Numbers Version 4&#46;0</span> &#40;Winpepi&#44; Pepi&#8208;for&#8208;Windows&#44; NY&#44; EUA&#41; foi usado para randomizar oito datas mensais durante um ano&#46; Foram inclu&#237;dos no estudo todos os neonatos nascidos nos dias randomizados para a coleta de dados&#44; cujos respons&#225;veis concordaram em participar e assinar o Termo de Consentimento Livre e Esclarecido&#46; Foram exclu&#237;dos da an&#225;lise deste estudo os neonatos admitidos na Unidade de Tratamento Intensivo &#40;UTI&#41;&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">O exame dermatol&#243;gico foi feito por dermatologistas com treinamento padronizado e com aux&#237;lio da dermatoscopia&#46; As reavalia&#231;&#245;es foram feitas no Centro de Pesquisa Cl&#237;nica do HCPA&#46; O estudo foi aprovado no Comit&#234; de &#201;tica em Pesquisa das tr&#234;s Institui&#231;&#245;es &#224;s quais foi submetido&#58; HCPA <span class="elsevierStyleItalic">&#8211;</span> Projeto 1101013&#59; Complexo Hospitalar Santa Casa de Porto Alegre <span class="elsevierStyleItalic">&#8211;</span> Protocolo 3513&#47;1 e Hospital F&#234;mina <span class="elsevierStyleItalic">&#8211;</span> Projeto 11&#8208;065&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Os achados dermatol&#243;gicos foram classificados em&#58; les&#245;es cut&#226;neas transit&#243;rias neonatais&#44; marcas de nascimento&#44; pustulose benigna neonatal&#44; hemangioma ou precursores&#44; les&#245;es secund&#225;rias ao trauma&#44; malforma&#231;&#227;o cut&#226;nea e doen&#231;a infecciosa&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Os dados obtidos foram analisados no programa SPSS v&#46;20&#46;0 &#40;IBM Corp&#46; Released 2013&#46; IBM SPSS Statistics para Windows&#44; vers&#227;o 22&#46;0&#46; NY&#44; EUA&#41;&#46; Foram descritas as vari&#225;veis categ&#243;ricas por frequ&#234;ncias e percentuais e as preval&#234;ncias pelo seu intervalo de confian&#231;a de 95&#37;&#46; Na an&#225;lise secund&#225;ria dos dados&#44; as vari&#225;veis categ&#243;ricas foram associadas entre si pelo teste de qui&#8208;quadrado e as quantitativas foram comparadas pelo teste <span class="elsevierStyleItalic">t</span> de Student para amostras independentes&#46; Para avaliar poss&#237;veis associa&#231;&#245;es entre diferentes fatores em estudo e les&#245;es e ajustar para potenciais fatores de confus&#227;o&#44; foi feita uma an&#225;lise multivari&#225;vel de Regress&#227;o de Poisson com vari&#226;ncia robusta&#46; Foi considerado um n&#237;vel de signific&#226;ncia entre 2 e 5&#37;&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="par0040" class="elsevierStylePara elsevierViewall">Dos 2&#46;839 neonatos selecionados para participar do estudo&#44; 309 foram exclu&#237;dos por terem sido admitidos em Unidade de Tratamento Intensivo &#40;UTI&#41;&#46; A idade gestacional m&#233;dia foi de 38&#44;41 semanas &#40;mediana 39 &#8211; percentil 25&#8208;50 e 75&#58; 38&#8208;39 e 40 respectivamente&#41;&#59; a cor do RN foi predominantemente branca&#59; 57&#44;6&#37; nasceram de parto vaginal&#46; Quanto &#224;s m&#227;es&#44; 92&#44;5&#37; fizeram o pr&#233;&#8208;natal&#44; 59&#44;8&#37; eram mult&#237;paras e 44&#44;1&#37; tinham algum fator de risco gestacional &#40;FRG&#41;&#46; A <a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a> mostra as caracter&#237;sticas neonatais e os FRG&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">Dos neonatos examinados&#44; 95&#44;8&#37; apresentavam algum achado dermatol&#243;gico&#46; Desses&#44; 88&#44;6&#37; tinham alguma manifesta&#231;&#227;o cut&#226;nea transit&#243;ria neonatal&#44; 42&#44;6&#37; marca de nascimento&#44; 26&#44;8&#37; pustulose benigna neonatal&#44; 2&#37; alguma les&#227;o cut&#226;nea secund&#225;ria ao trauma&#44; 0&#44;5&#37; malforma&#231;&#227;o cut&#226;nea e 0&#44;1&#37; doen&#231;a infecciosa &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabela 2</a>&#41;&#46; Foi observada uma m&#233;dia de 3&#44;23 achados dermatol&#243;gicos por neonato com alguma manifesta&#231;&#227;o cut&#226;nea&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">O achado dermatol&#243;gico mais frequente foi o lanugo&#44; encontrado em 38&#44;9&#37; dos RN&#44; seguido por hiperplasia de gl&#226;ndulas seb&#225;ceas &#40;35&#37;&#41;&#44; melanocitose d&#233;rmica &#40;24&#44;6&#37;&#41;&#44; descama&#231;&#227;o da pele &#40;23&#44;3&#37;&#41;&#44; ETN &#40;23&#37;&#41;&#44; mancha salm&#227;o &#40;20&#44;4&#37;&#41;&#44; eritema da pele &#40;19&#37;&#41;&#44; hiperpigmenta&#231;&#227;o da genit&#225;lia &#40;18&#44;4&#37;&#41;&#44; edema palpebral &#40;17&#44;4&#37;&#41;&#44; cistos de m&#237;lia &#40;17&#44;3&#37;&#41;&#44; hipertrofia da genit&#225;lia &#40;12&#37;&#41;&#44; cianose das extremidades &#40;11&#44;7&#37;&#41; e xerose cut&#226;nea &#40;10&#44;9&#37;&#41; &#40;<a class="elsevierStyleCrossRefs" href="#fig0005">figs&#46; 1 e 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">Foi encontrada&#44; tamb&#233;m&#44; uma preval&#234;ncia de 3&#44;7&#37; de MPTN&#44; 2&#44;8&#37; de pele moteada&#59; 2&#44;6&#37; de bossa&#59; 2&#44;3 de mili&#225;ria cristalina&#59; 1&#44;8&#37; de mancha caf&#233; com leite solit&#225;ria e de melanocitose d&#233;rmica aberrante&#59; 1&#44;4&#37; de v&#233;rnix caseosa&#59; 1&#44;2&#37; de nevo cong&#234;nito&#59; 1&#37; de m&#225;scara ecm&#243;tica e 0&#44;1&#37; hematoma por pun&#231;&#227;o&#59; 0&#44;74&#37; de hemangioma ou precursor de hemangioma&#59; 0&#44;7&#37; de mili&#225;ria rubra&#44; 0&#44;5&#37; de c&#233;falo&#8208;hematoma&#59; 0&#44;4&#37; de p&#243;lipo anexial perimamilar&#59; 0&#44;3&#37; de nevo seb&#225;ceo&#44; bolhas de suc&#231;&#227;o e mudan&#231;a de cor Arlequin&#46; Foi observada uma preval&#234;ncia de 0&#44;14&#37; de doen&#231;as infecciosas&#44; que corresponderam a tr&#234;s casos de s&#237;filis cong&#234;nita e um caso de impetigo bolhoso&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">Foi observada nos prematuros maior preval&#234;ncia de lanugo &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Os RN a termo apresentaram mais pustuloses benignas neonatais e cistos de m&#237;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; J&#225; no p&#243;s&#8208;maturo foi maior a preval&#234;ncia de les&#245;es de pele transit&#243;rias &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; como a hiperpigmenta&#231;&#227;o da genit&#225;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e a xerose cut&#226;nea &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;02&#41;&#59; e tamb&#233;m de marcas de nascimento &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; como a mancha mong&#243;lica e a mancha salm&#227;o &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; O ETN apresentou associa&#231;&#227;o positiva com a idade gestacional &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Quanto &#224; etnia do RN&#44; foi observada nos RN brancos maior preval&#234;ncia de ETN &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; al&#233;m de algumas les&#245;es transit&#243;rias&#44; como cistos de m&#237;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;005&#41;&#44; eritema da pele &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; hiperplasia de gl&#226;ndulas seb&#225;ceas &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;005&#41; e mancha salm&#227;o &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;017&#41;&#46; Nos RN negros&#44; foram mais prevalentes a mancha mong&#243;lica&#44; a descama&#231;&#227;o das extremidades&#44; a hiperpigmenta&#231;&#227;o da genit&#225;lia e a xerose cut&#226;nea &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Nos pardos foi maior a preval&#234;ncia de achados dermatol&#243;gicos neonatais&#44; devido aos achados transit&#243;rios &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; como a hipertrofia da genit&#225;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Quanto ao g&#234;nero&#44; foi observado no RN feminino maior preval&#234;ncia dos achados transit&#243;rios &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;026&#41;&#46; J&#225; nos masculinos foram mais prevalentes o ETN &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;002&#41; e a hiperpigmenta&#231;&#227;o da genit&#225;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Em rela&#231;&#227;o ao &#193;pgar no primeiro minuto de vida&#44; observamos maior preval&#234;ncia de ETN em neonatos com &#237;ndice de &#193;pgar entre 8 e 10 &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; E para o &#237;ndice de &#193;pgar no 5&#176; minuto de vida&#44; os neonatos com &#193;pgar entre 0 e 3 apresentaram maior preval&#234;ncia de lanugo&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">O tipo de parto tamb&#233;m influenciou na presen&#231;a de alguns achados dermatol&#243;gicos&#46; Os neonatos nascidos de parto vaginal tiveram uma preval&#234;ncia maior de hiperpigmenta&#231;&#227;o da genit&#225;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e hipertrofia da genit&#225;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;011&#41;&#59; e tamb&#233;m de marcas de nascimento &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Os RN nascidos por parto vaginal com aux&#237;lio apresentaram mais descama&#231;&#227;o da pele &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;048&#41;&#44; descama&#231;&#227;o das extremidades &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;002&#41; e edema e eritema palpebral &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; O parto vaginal foi feito com maior frequ&#234;ncia nos RN com peso entre 2&#46;500 e 3&#46;999<span class="elsevierStyleHsp" style=""></span>g e nos RN a termo ou p&#243;s&#8208;termo &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Ao avaliar os FRG&#44; observamos que os neonatos nascidos de m&#227;es com algum fator de risco apresentaram uma preval&#234;ncia maior de achados dermatol&#243;gicos &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;047&#41;&#46; Diferen&#231;a que &#233; observada tamb&#233;m para as les&#245;es transit&#243;rias neonatais &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; J&#225; os RN de m&#227;es sem fatores de risco apresentaram maior preval&#234;ncia de marcas de nascimento &#40;0&#44;016&#41; e de ETN &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Os RN de m&#227;es que tiveram diabetes gestacional apresentaram mais eritema da pele &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;048&#41; e menor preval&#234;ncia de lanugo &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Ao avaliar hipertens&#227;o gestacional foi observada uma preval&#234;ncia maior de eritema de pele &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;013&#41; e de hipertrofia da genit&#225;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;028&#41;&#46; Foi observado que 1&#44;7&#37; das m&#227;es apresentava sorologia positiva para HIV&#44; por&#233;m n&#227;o foi encontrada associa&#231;&#227;o com a presen&#231;a de achados dermatol&#243;gicos neonatais&#46; A idade materna tamb&#233;m n&#227;o influenciou na presen&#231;a de achados dermatol&#243;gicos neonatais&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Quanto &#224; sazonalidade&#44; observou&#8208;se que no ver&#227;o ocorreram mais les&#245;es transit&#243;rias &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;008&#41;&#44; como a hiperplasia de gl&#226;ndula seb&#225;cea &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;049&#41; e a xerose cut&#226;nea &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Na primavera foi maior a preval&#234;ncia de ETN &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;004&#41;&#46; No outono foi maior a preval&#234;ncia de edema palpebral &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e eritema da pele &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#59; nos meses de inverno foram mais prevalentes a descama&#231;&#227;o cut&#226;nea &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e a hipertrofia da genit&#225;lia &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discuss&#227;o</span><p id="par0095" class="elsevierStylePara elsevierViewall">Diversos autores avaliaram a preval&#234;ncia dos achados dermatol&#243;gicos neonatais em diferentes pa&#237;ses&#46; Contudo n&#227;o h&#225; uniformiza&#231;&#227;o na terminologia usada e tampouco no delineamento&#44; o que dificulta a compara&#231;&#227;o entre os trabalhos&#46; N&#227;o foram encontrados outros autores que avaliaram a sazonalidade dos achados dermatol&#243;gicos neonatais&#44; este estudo &#233; in&#233;dito quanto a essa vari&#225;vel&#46; Apesar da diferen&#231;a metodol&#243;gica entre os trabalhos&#44; a preval&#234;ncia dos achados dermatol&#243;gicos encontrada &#233; semelhante &#224; descrita por outros autores&#44; que observaram esses achados em 90&#37; dos RN&#46; Por&#233;m&#44; maior do que o relatado por autores da Turquia&#44; que encontraram uma frequ&#234;ncia de 67&#44;3&#37; de achados cut&#226;neos em 1&#46;234 neonatos com at&#233; 48 horas de vida&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">6</span></a></p><p id="par0100" class="elsevierStylePara elsevierViewall">A descama&#231;&#227;o fisiol&#243;gica &#233; observada na maioria dos neonatos e costuma ser mais intensa entre o sexto e s&#233;timo dia de vida&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">12</span></a> O resultado deste estudo mostra diferen&#231;as em rela&#231;&#227;o a outros dados j&#225; publicados&#59; foi menor do que o relatado por autores que examinaram neonatos com uma semana de vida<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">12</span></a> e maior do que o relatado por autores que avaliaram RN com at&#233; 48 horas de vida&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">3</span></a> Acreditamos que essa diferen&#231;a tenha sido porque o exame dermatol&#243;gico foi feito nas primeiras 72 horas de vida&#44; per&#237;odo no qual esse achado costuma ser menos intenso&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">A preval&#234;ncia da mancha salm&#227;o foi menor do que a relatada por alguns autores&#44; que observaram uma preval&#234;ncia de 26 a 83&#37;&#44;<a class="elsevierStyleCrossRefs" href="#bib0140"><span class="elsevierStyleSup">3&#44;13&#44;14</span></a> e semelhante &#224; relatada por outros&#44; como o estudo feito na Turquia que mostrou uma preval&#234;ncia de 19&#44;2&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">15</span></a> J&#225; a preval&#234;ncia de melanocitose d&#233;rmica foi maior do que a descrita para crian&#231;as da etnia branca&#44; que foi relatada por ocorrer em menos de 10&#37; RN brancos&#44;<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">2&#44;13</span></a> provavelmente devido &#224;s caracter&#237;sticas de miscigena&#231;&#227;o da popula&#231;&#227;o do estudo&#46; Tanto a mancha salm&#227;o quanto a melanocitose d&#233;rmica apresentaram correla&#231;&#227;o positiva com a idade gestacional e&#44; apesar do n&#250;mero de RN p&#243;s&#8208;termo examinados neste estudo ter sido pequeno&#44; pode indicar que as marcas de nascimento possam ser um marcador de maturidade cut&#226;nea no neonato&#46; Ademais&#44; a diferen&#231;a com os dados publicados por outros autores pode indicar que as caracter&#237;sticas populacionais apresentaram influ&#234;ncia importante na presen&#231;a das marcas de nascimento&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">A preval&#234;ncia de cistos de m&#237;lia foi semelhante &#224; encontrada em RN espanh&#243;is&#44; que foi de 16&#44;6&#37;&#44;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a> entretanto maior do que a relatada por autores americanos&#44; que foi de 8&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">13</span></a> Os cistos de m&#237;lia foram mais prevalentes nos neonatos a termo&#44; pode tamb&#233;m ser um indicador de maturidade cut&#226;nea&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Foi observada uma preval&#234;ncia de v&#233;rnix caseosa menor do que a relatada em RN espanh&#243;is&#44; que foi de 42&#44;9&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a> Supomos que essa diferen&#231;a seja porque a maioria dos neonatos examinados j&#225; havia recebido o primeiro banho&#44; que nas maternidades nas quais o estudo foi conduzido &#233; habitualmente dado entre 24 e 48 horas ap&#243;s o nascimento&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Foi observada uma preval&#234;ncia maior do que a esperada para as primeiras 48 horas de vida das pustuloses benignas neonatais &#40;PBN&#41;&#46;<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">17&#44;18</span></a> A preval&#234;ncia de ETN foi semelhante &#224; relatada em um estudo prospectivo conduzido na Espanha com 365 RN que encontrou uma preval&#234;ncia de 25&#44;3&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">19</span></a> No entanto&#44; foi observado que o ETN ocorreu com maior frequ&#234;ncia do que o esperado para RN dentro das primeiras 48 horas de vida&#44; quando comparado com um estudo feito na Calif&#243;rnia que mostrou uma preval&#234;ncia de 7&#37; de ETN em neonatos com at&#233; 48 horas de vida&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">13</span></a> Diferentemente dos autores que relataram que ETN foi mais prevalente em parto ces&#225;rio<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">4&#44;6</span></a> e de outros que observaram maior preval&#234;ncia de ETN nos RN de parto vaginal&#44;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">20</span></a> neste estudo n&#227;o foi observada diferen&#231;a entre o tipo de parto e a frequ&#234;ncia de ETN&#46; A preval&#234;ncia de MPTN tamb&#233;m foi maior do que a esperada para uma popula&#231;&#227;o predominantemente branca&#44; provavelmente devido &#224;s caracter&#237;sticas de miscigena&#231;&#227;o da popula&#231;&#227;o do estudo&#46; O ETN foi mais prevalente nos meses de primavera&#44; semelhante ao observado por outros autores que relataram que o ETN &#233; mais comum em clima quente e &#250;mido&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">21</span></a> Tamb&#233;m foi observado que o ETN foi mais prevalente em RN que nasceram em &#243;timas condi&#231;&#245;es e sem FRG&#44; o que pode indicar ser o ETN um achado dermatol&#243;gico do RN saud&#225;vel&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">N&#227;o observamos rela&#231;&#227;o entre prematuridade e hiperpigmenta&#231;&#227;o genital ou c&#250;tis marmorata como relatado por alguns autores&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">20</span></a> Ao contr&#225;rio&#44; encontramos maior frequ&#234;ncia de hiperpigmenta&#231;&#227;o da genit&#225;lia no RN p&#243;s&#8208;termo&#44; o que tamb&#233;m poderia ser um indicador de maturidade cut&#226;nea&#46; N&#227;o foi encontrada rela&#231;&#227;o com a maturidade do RN e hiperplasia de gl&#226;ndulas seb&#225;ceas e descama&#231;&#227;o cut&#226;nea como relatado por outros autores&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a></p><p id="par0130" class="elsevierStylePara elsevierViewall">A frequ&#234;ncia dos achados dermatol&#243;gicos neonatais foi maior em RN de m&#227;es com FRG devido &#224;s les&#245;es transit&#243;rias neonatais&#46; Pode indicar que determinadas comorbidades maternas possam ter influ&#234;ncia sobre a pele do RN&#44; como o diabetes e a hipertens&#227;o gestacional&#44; que tiveram associa&#231;&#227;o com o eritema da pele e a hipertens&#227;o gestacional com a hipertrofia da genit&#225;lia&#46; Tamb&#233;m foi encontrada uma preval&#234;ncia maior de hipertrofia da genit&#225;lia nos RN de m&#227;es que tiveram HAS gestacional&#46; Outros autores encontraram associa&#231;&#227;o entre hipertrofia da genit&#225;lia com doen&#231;a gestacional e uso de medicamentos durante a gesta&#231;&#227;o&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">22</span></a> No entanto&#44; n&#227;o foram avaliados os medicamentos usados durante a gesta&#231;&#227;o neste estudo&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">Foi observada uma preval&#234;ncia de sorologia para o HIV positiva na gesta&#231;&#227;o maior do que a esperada para mulheres de todas as idades no Brasil&#44; que &#233; de 0&#44;42&#37;&#59; maior do que a relatada por outros autores para gestantes entre 15 e 24 anos atendidas em hospitais cl&#237;nicos brasileiros&#44; que foi de 0&#44;7&#37;&#44;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">23</span></a> e tamb&#233;m maior do que a relatada em gestantes de outras regi&#245;es do Brasil&#46;<a class="elsevierStyleCrossRefs" href="#bib0240"><span class="elsevierStyleSup">24&#44;25</span></a> Apesar de a preval&#234;ncia de HIV positivo ter sido alta&#44; na compara&#231;&#227;o com outras regi&#245;es do Brasil&#44; n&#227;o teve associa&#231;&#227;o com les&#245;es cut&#226;neas&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">A preval&#234;ncia de les&#245;es infecciosas neste estudo foi menor do que a relatada para RN na UTI neonatal&#44; que foi de 4&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a> Provavelmente porque este estudo incluiu apenas os neonatos no alojamento conjunto&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">Quanto &#224; sazonalidade dos achados dermatol&#243;gicos&#44; acreditamos que a maior preval&#234;ncia de hiperplasia de gl&#226;ndulas seb&#225;ceas nos meses de ver&#227;o possa ser devida a uma maior atividade glandular nos meses mais quentes&#46; O ETN foi mais prevalente na primavera&#44; como relatado por outros autores&#44; a preval&#234;ncia de ETN pode sofrer influ&#234;ncia do clima quente e &#250;mido&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">21</span></a> A temperatura mais fria&#44; acompanhada da umidade&#44; caracter&#237;stica dos meses de inverno&#44; pode precipitar a descama&#231;&#227;o cut&#226;nea nos neonatos&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">Os achados dermatol&#243;gicos s&#227;o frequentemente identificados nos RN&#44; muitos caracterizam a pele do neonato&#44; o que justifica um exame dermatol&#243;gico detalhado&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">24</span></a> Os achados cut&#226;neos mais comumente observados em neonatos s&#227;o em geral transit&#243;rios e resultam da resposta fisiol&#243;gica normal&#46; Usualmente se limitam aos primeiros dias ou semanas de vida&#44; portanto raramente s&#227;o avaliados por dermatologistas&#46; A correta identifica&#231;&#227;o desses achados &#233; importante para saber diferenciar dos achados patol&#243;gicos&#44; evitar procedimentos diagn&#243;sticos e terap&#234;uticos desnecess&#225;rios&#44; bem como diminuir a preocupa&#231;&#245;es dos pais e assistentes&#46;<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">4</span></a></p><p id="par0155" class="elsevierStylePara elsevierViewall">Este estudo multic&#234;ntrico com dados coletados durante um ano&#44; em uma cidade com as esta&#231;&#245;es clim&#225;ticas bem definidas&#44; com o uso da nomenclatura dermatol&#243;gica correta e com o exame da pele feito por especialistas&#44; fornece dados importantes sobre a preval&#234;ncia dos achados dermatol&#243;gicos nas primeiras 72 horas de vida&#44; bem como a influ&#234;ncia da etnicidade&#44; dos FRG e da sazonalidade&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">Foi observada uma alta preval&#234;ncia de achados dermatol&#243;gicos neonatais nas primeiras 72 horas de vida na regi&#227;o na qual o estudo foi conduzido&#44; o que evidencia a import&#226;ncia do exame dermatol&#243;gico detalhado&#46; A etnia do neonato e os fatores de risco gestacionais maternos influenciaram na presen&#231;a de achados dermatol&#243;gicos&#46; Ademais&#44; foi encontrada associa&#231;&#227;o entre manifesta&#231;&#245;es cut&#226;neas espec&#237;ficas e determinadas caracter&#237;sticas neonatais&#44; tais como a idade gestacional&#44; a etnia&#44; o g&#234;nero e o &#237;ndice de &#193;pgar no primeiro e quinto minuto de vida&#59; e com as caracter&#237;sticas gestacionais&#44; como o tipo de parto&#46; Os achados dermatol&#243;gicos mais prevalentes tamb&#233;m foram distintos nas diferentes esta&#231;&#245;es no ano&#46;</p><p id="par0165" class="elsevierStylePara elsevierViewall">A diferen&#231;a da preval&#234;ncia das manifesta&#231;&#245;es cut&#226;neas em compara&#231;&#227;o com outros estudos mostra que tanto as caracter&#237;sticas populacionais como o per&#237;odo em que a pele do RN foi examinada podem influenciar na presen&#231;a de achados dermatol&#243;gicos&#44; por&#233;m essa rela&#231;&#227;o ainda n&#227;o est&#225; clara&#44; h&#225; a necessidade de mais estudos espec&#237;ficos&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Financiamento</span><p id="par0170" class="elsevierStylePara elsevierViewall">Fundo de Incentivo &#224; Pesquisa do Hospital de Cl&#237;nicas de Porto Alegre &#40;Fipe&#41;&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Conflitos de interesse</span><p id="par0175" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
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            0 => "Newborn"
            1 => "Neonatology"
            2 => "Child health services"
            3 => "Child health"
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            0 => "Rec&#233;m&#8208;nascido"
            1 => "Neonatologia"
            2 => "Servi&#231;os de sa&#250;de da crian&#231;a"
            3 => "Sa&#250;de da crian&#231;a"
            4 => "Cuidado do lactente"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To determine the prevalence of neonatal dermatological findings and analyze whether there is an association between these findings and neonatal and pregnancy characteristics and seasonality&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Newborns from three maternity hospitals in a Brazilian capital city were randomly selected to undergo dermatological assessment by dermatologists&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">2938 neonates aged up to three days of life were randomly selected&#44; of whom 309 were excluded due to Intensive Care Unit admission&#46; Of the 2530 assessed neonates&#44; 49&#46;6&#37; were Caucasians&#44; 50&#46;5&#37; were males&#44; 57&#46;6&#37; were born by vaginal delivery&#44; and 92&#46;5&#37; of the mothers received prenatal care&#46; Some dermatological finding was observed in 95&#46;8&#37; of neonates&#59; of these&#44; 88&#46;6&#37; had transient neonatal skin conditions&#44; 42&#46;6&#37; had congenital birthmarks&#44; 26&#46;8&#37; had some benign neonatal pustulosis&#44; 2&#37; had lesions secondary to trauma &#40;including scratches&#41;&#44; 0&#46;5&#37; had skin malformations&#44; and 0&#46;1&#37; had an infectious disease&#46; The most prevalent dermatological findings were&#58; lanugo&#44; which was observed in 38&#46;9&#37; of the newborns&#44; sebaceous hyperplasia &#40;35&#37;&#41;&#44; dermal melanocytosis &#40;24&#46;61&#37;&#41;&#44; skin desquamation &#40;23&#46;3&#37;&#41;&#44; erythema toxicum neonatorum &#40;23&#37;&#41;&#44; salmon patch &#40;20&#46;4&#37;&#41;&#44; skin erythema &#40;19&#37;&#41;&#44; genital hyperpigmentation &#40;18&#46;4&#37;&#41;&#44; eyelid edema &#40;17&#46;4&#37;&#41;&#44; milia &#40;17&#46;3&#37;&#41;&#44; genital hypertrophy &#40;12&#37;&#41;&#44; and skin xerosis &#40;10&#46;9&#37;&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Dermatological findings are frequent during the first days of life and some of them characterize the newborn&#39;s skin&#46; Mixed&#8208;race newborns and those whose mothers had some gestational risk factor had more dermatological findings&#46; The gestational age&#44; newborn&#39;s ethnicity&#44; gender&#44; Apgar at the first and fifth minutes of life&#44; type of delivery&#44; and seasonality influenced the presence of specific neonatal dermatological findings&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Verificar a preval&#234;ncia dos achados dermatol&#243;gicos nos primeiros dias de vida e analisar se h&#225; associa&#231;&#227;o com caracter&#237;sticas neonatais&#44; gestacionais e sazonalidade&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Rec&#233;m&#8208;nascidos de tr&#234;s maternidades de uma capital brasileira foram selecionados aleatoriamente para serem submetidos ao exame dermatol&#243;gico feito por dermatologistas&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Foram selecionados aleatoriamente 2&#46;839 neonatos com at&#233; 72 horas de vida&#44; 309 foram exclu&#237;dos por terem sido admitidos em Unidade de Tratamento Intensivo&#46; Dos 2&#46;530 neonatos examinados&#44; 49&#44;6&#37; eram da etnia branca e 50&#44;5&#37; do sexo masculino&#46; Foi observado algum achado dermatol&#243;gico em 95&#44;8&#37; dos rec&#233;m&#8208;nascidos&#59; desses&#44; 88&#44;6&#37; tinham les&#245;es cut&#226;neas transit&#243;rias neonatais&#44; 42&#44;6&#37; marca de nascimento&#44; 26&#44;8&#37; pustulose benigna neonatal&#44; 2&#37; les&#245;es secund&#225;rias ao trauma&#44; 0&#44;5&#37; malforma&#231;&#227;o cut&#226;nea e 0&#44;1&#37; doen&#231;a infecciosa&#46; O achado dermatol&#243;gico mais frequente foi o lanugo&#44; observado em 38&#44;9&#37; dos neonatos&#44; seguido por hiperplasia de gl&#226;ndulas seb&#225;ceas &#40;35&#37;&#41;&#44; melanocitose d&#233;rmica &#40;24&#44;6&#37;&#41;&#44; descama&#231;&#227;o da pele &#40;23&#44;3&#37;&#41;&#44; eritema t&#243;xico neonatal &#40;23&#37;&#41;&#44; mancha salm&#227;o &#40;20&#44;4&#37;&#41;&#44; eritema da pele &#40;19&#37;&#41;&#44; hiperpigmenta&#231;&#227;o da genit&#225;lia &#40;18&#44;4&#37;&#41;&#44; edema palpebral &#40;17&#44;4&#37;&#41;&#44; cistos de m&#237;lia &#40;17&#44;3&#37;&#41;&#44; hipertrofia da genit&#225;lia &#40;12&#37;&#41; e xerose cut&#226;nea &#40;10&#44;9&#37;&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#245;es</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Os achados dermatol&#243;gicos s&#227;o frequentemente identificados nos primeiros dias de vida e muitos deles caracterizam a pele do rec&#233;m&#8208;nascido&#46; Os neonatos pardos e aqueles cujas m&#227;es apresentavam algum fator de risco gestacional tiveram mais achados dermatol&#243;gicos&#46; A idade gestacional&#44; a etnia do neonato&#44; o g&#234;nero&#44; o &#237;ndice de &#193;pgar&#44; o tipo de parto e a sazonalidade influenciaram na presen&#231;a de manifesta&#231;&#245;es cut&#226;neas espec&#237;ficas&#46;</p></span>"
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            "identificador" => "abst0025"
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      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Como citar este artigo&#58; Reginatto FP&#44; DeVilla D&#44; Muller FM&#44; Peruzzo J&#44; Peres LP&#44; Steglich RB&#44; et al&#46; Prevalence and characterization of neonatal skin disorders in the first 72 h of life&#46; J Pediatr &#40;Rio J&#41;&#46; 2017&#59;93&#58;238&#8211;45&#46;</p>"
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        "etiqueta" => "&#9734;&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0010">O trabalho est&#225; vinculado ao Programa de P&#243;s&#8208;Gradua&#231;&#227;o em Sa&#250;de da Crian&#231;a e Adolescente&#44; Universidade Federal do Rio Grande do Sul &#40;UFRGS&#41;&#59; e ao Hospital de Cl&#237;nicas de Porto Alegre &#40;HCPA&#41;&#44; Universidade Federal do Rio Grande do Sul &#40;UFRGS&#41;&#44; Porto Alegre&#44; RS&#44; Brasil&#46;</p>"
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        "descripcion" => array:1 [
          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41; Lanugo&#59; &#40;B&#41; cistos de m&#237;lia do dorso nasal&#59; &#40;C&#41; Eritema da pele&#59; &#40;D&#41; melanocitose d&#233;rmica&#46;</p>"
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        "descripcion" => array:1 [
          "pt" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41; poliose&#59; &#40;B&#41; nevo melanoc&#237;tico no couro cabeludo&#59; &#40;C&#41; descama&#231;&#227;o da pele do neonato&#59; &#40;D&#41; hemangioma&#46;</p>"
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Idade gestacional</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#60; 37 semanas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>37&#8208;42 semanas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">91&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#62; ou igual a 42 semanas&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Cor&#47;etnia do RN</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Branco&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Negro&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#205;ndio &#40;m&#227;e ou pai &#237;ndio&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Asi&#225;tico &#40;m&#227;e ou pai asi&#225;tico&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N&#227;o sabiam ou n&#227;o informaram a cor do pai&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Sexo do RN</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Feminino&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Masculino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">50&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Peso ao nascimento &#40;g&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>1&#46;500&#8208;2&#46;500<span class="elsevierStyleHsp" style=""></span>g&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>2&#46;500&#8208;4&#46;000<span class="elsevierStyleHsp" style=""></span>g&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#8805; 4&#46;000<span class="elsevierStyleHsp" style=""></span>g&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">&#193;pgar no primeiro minuto</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>7&#8208;10&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">99&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#60; 7&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">M&#227;es fator de risco gestacional</span>&nbsp;\t\t\t\t\t\t\n
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Achados dermatol&#243;gicos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Preval&#234;ncia &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">IC 95&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Presen&#231;a de les&#245;es de pele</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">95&#44;1&#8208;96&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Les&#245;es transit&#243;rias</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">88&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">87&#8208;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bolhas de suc&#231;&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Bossa&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cefalo&#8208;hematoma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cianose de extremidades&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#8208;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cistos de m&#237;lia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">16&#8208;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dermatite perineal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dermatite seborreica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Descama&#231;&#227;o da pele ou extremidades&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">23&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22&#8208;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Edema palpebral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">16&#8208;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eritema da pele&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">18&#8208;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hiperplasia de gl&#226;ndula seb&#225;cea&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">34&#8208;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hiperpigmenta&#231;&#227;o da genit&#225;lia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17&#8208;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertrofia genit&#225;lia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#8208;13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Icter&#237;cia fisiol&#243;gica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lanugo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">38&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">37&#8208;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>M&#225;scara ecm&#243;tica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Melanon&#237;quia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mili&#225;ria cristalina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mili&#225;ria rubra&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mudan&#231;a de cor Arlequin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pele moteada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Rea&#231;&#227;o ao col&#237;rio de nitrato de prata&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sangramento vaginal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Secre&#231;&#227;o vaginal clara&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>V&#233;rnix caseoso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Xerose cut&#226;nea&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10&#8208;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Marcas de nascimento</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">40&#8208;44&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Manchas caf&#233; com leite m&#250;ltiplas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mancha caf&#233; com leite solit&#225;ria&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Melanocitose d&#233;rmica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">23&#8208;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Lombar e sacra&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Localiza&#231;&#227;o aberrante&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mancha salm&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19&#8208;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mancha vinho do Porto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleItalic">Nevo cong&#234;nito</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>&#60; 1&#44;5<span class="elsevierStyleHsp" style=""></span>cm&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>1&#44;5&#8208;10<span class="elsevierStyleHsp" style=""></span>cm&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nevo despigmentado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nevo seb&#225;ceo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hemangioma e linfangioma</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;74&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hemangioma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Precursor hemangioma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Linfangioma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Pustuloses benignas neonatais</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">25&#8208;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eritema t&#243;xico neonatal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21&#8208;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Melanose pustulosa transit&#46; neonatal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pustulose cef&#225;lica benigna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Doen&#231;as infecciosas</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Impetigo bolhoso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>S&#237;filis cong&#234;nita&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Malforma&#231;&#245;es cut&#226;nea</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dedo supranumer&#225;rio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Episp&#225;dia ou hiposp&#225;dia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>F&#237;stula periauricular&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fissura labial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Malforma&#231;&#227;o da h&#233;lice orelha&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mamilo extranumer&#225;rio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>P&#233; torto cong&#234;nito&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>P&#243;lipo anexial perimamilar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Trago ou aur&#237;cula acess&#243;ria&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="3" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Les&#227;o por trauma</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Escoria&#231;&#245;es por arranhaduras&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Trauma pelo f&#243;rceps ou bisturi&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;59&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hematomas por pun&#231;&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fratura de clav&#237;cula&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "pt" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Preval&#234;ncia dos achados dermatol&#243;gicos de rec&#233;m&#8208;nascidos sem interna&#231;&#227;o na UTI neonatal&#44; em maternidades de Porto Alegre</p>"
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      "titulo" => "Refer&#234;ncias"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
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            0 => array:3 [
              "identificador" => "bib0130"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Enfermidades neonatales"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46; Larralde"
                            1 => "A&#46; Giachetti"
                            2 => "E&#46; Baselga"
                            3 => "M&#46;F&#46; Greco"
                            4 => "L&#46; Frieden"
                          ]
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                  ]
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                        "titulo" => "Dermatolog&#237;a pedi&#225;trica"
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                        "paginaFinal" => "53"
                        "edicion" => "2<span class="elsevierStyleSup">a</span> ed&#46;"
                        "serieFecha" => "2010"
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              "identificador" => "bib0135"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "One&#8208;year survey of cutaneous lesions in 1000 consecutive Iranian newborns"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "Z&#46; Moosavi"
                            1 => "T&#46; Hosseini"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1525-1470.2006.00172.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Dermatol"
                        "fecha" => "2006"
                        "volumen" => "23"
                        "paginaInicial" => "61"
                        "paginaFinal" => "63"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16445415"
                            "web" => "Medline"
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                      "titulo" => "Cutaneous lesions in Turkish neonates born in a teaching hospital"
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                          "autores" => array:4 [
                            0 => "G&#46; Gokdemir"
                            1 => "H&#46;K&#46; Erdogan"
                            2 => "A&#46; Koslu"
                            3 => "B&#46; Baksu"
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                    0 => array:2 [
                      "doi" => "10.4103/0378-6323.57742"
                      "Revista" => array:5 [
                        "tituloSerie" => "Indian J Dermatol Venereol Leprol"
                        "fecha" => "2009"
                        "volumen" => "75"
                        "paginaInicial" => "638"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19915262"
                            "web" => "Medline"
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              "identificador" => "bib0145"
              "etiqueta" => "4"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reci&#233;n nacido&#58; lesiones cut&#225;neas benignas transitorias"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Bautista"
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                      "LibroEditado" => array:5 [
                        "titulo" => "Protocolos de dermatolog&#237;a"
                        "paginaInicial" => "309"
                        "paginaFinal" => "316"
                        "edicion" => "2<span class="elsevierStyleSup">a</span> ed&#46;"
                        "serieFecha" => "2007"
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