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o pH da pele &#233; menor do que 5 &#40;pH<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>5&#41;&#46; J&#225; na pele mais fina&#44; especialmente em prematuros&#44; o pH tende ao neutro&#44; resulta em significativa perda da defesa contra a prolifera&#231;&#227;o microbiana e tamb&#233;m maior perda transepid&#233;rmica de &#225;gua&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> Ao nascimento&#44; o RN a termo tem um pH cut&#226;neo que varia de 6&#44;3 a 7&#44;5&#46;<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">10&#44;11</span></a> Dentro das duas primeiras semanas de vida&#44; o pH cai para aproximadamente 5&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">11</span></a> Entre a segunda e quarta semana de vida o pH torna&#8208;se gradativamente &#225;cido&#44; varia entre 4&#44;2 a 5&#44;9&#44; depende da &#225;rea do corpo&#44; prevalecem valores maiores nas axilas&#44; na regi&#227;o genital e na interdigital&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">12</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">O banho &#233; um momento de descontra&#231;&#227;o e de intera&#231;&#227;o m&#227;e e filho&#44; al&#233;m de indispens&#225;vel para a manuten&#231;&#227;o da higiene e sa&#250;de da pele&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">13</span></a> O banho mant&#233;m a pele livre de subst&#226;ncias irritantes &#40;saliva&#44; secre&#231;&#245;es nasais&#44; urina&#44; fezes e enzimas fecais&#41;&#44; p&#243; e germes&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">1</span></a> Segundo a Organiza&#231;&#227;o Mundial de Sa&#250;de &#40;OMS&#41;&#44; &#233; recomendado que o primeiro banho seja dado seis horas ap&#243;s o parto&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> Sugeriu&#8208;se que o banho apenas com &#225;gua fosse o m&#233;todo menos nocivo de limpeza do RN&#44; foi adotado nos protocolos nacionais de cuidados p&#243;s&#8208;natais em muitos pa&#237;ses&#44; dentre eles a Inglaterra&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> Entretanto&#44; a capacidade de tamponamento da &#225;gua tem sido questionada&#44; j&#225; que ela pode aumentar o pH da pele de 5&#44;5 para 7&#44;5&#46; Al&#233;m disso&#44; o emprego isolado de &#225;gua foi identificado como um agente de limpeza inefetivo&#44; j&#225; que n&#227;o remove subst&#226;ncias oleosas como fezes e sebo&#46;<a class="elsevierStyleCrossRefs" href="#bib0180"><span class="elsevierStyleSup">14&#44;15</span></a> Os protocolos americanos recomendam o uso de &#225;gua pot&#225;vel morna&#44; com a op&#231;&#227;o de associar um produto de limpeza suave que apresente pH fisiologicamente adequado &#40;5&#44;5 a 7&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">14</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Acredita&#8208;se que o emprego repetido dos agentes de limpeza pode alterar o pH da superf&#237;cie da pele em longo prazo&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">12</span></a> Os sabonetes tradicionais t&#234;m pH alcalino&#44; que pode destruir a camada lip&#237;dica da pele&#44;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> elevar o pH da pele acima de 8 e levar a ressecamento e irrita&#231;&#227;o&#46;<a class="elsevierStyleCrossRefs" href="#bib0170"><span class="elsevierStyleSup">12&#44;14&#44;16&#8211;19</span></a> Um pH de 7&#44;5 &#233; capaz de aumentar a atividade das proteases cut&#226;neas e inibir a s&#237;ntese da lamela lip&#237;dica e levar a um colapso da barreira cut&#226;nea&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">14</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Os sindets s&#227;o formulados a partir de tensoativos sint&#233;ticos que t&#234;m bom efeito detergente&#44; pH neutro ou ligeiramente &#225;cido e provocam menos irrita&#231;&#227;o&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> Estudos demonstram que o banho com esse tipo de sabonete &#233; compar&#225;vel ao banho somente com &#225;gua ou at&#233; superior a ele&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">20</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Um bom produto de limpeza para os RN deve ter pH pr&#243;ximo de 5&#44;5 e algum tamp&#227;o com capacidade para manter o pH pr&#243;ximo a isso&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">14</span></a> As ind&#250;strias de cosm&#233;ticos colocam no mercado uma grande variedade desses produtos e classificam&#8208;nos como &#8220;suaves&#8221;&#46; No entanto&#44; n&#227;o existe um crit&#233;rio internacional para estabelecer suavidade em agentes de limpeza e geralmente v&#225;rios produtos destinados &#224; peles sens&#237;veis apresentam efeitos irritativos significantes&#46;<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">21</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Assim&#44; o principal objetivo deste estudo foi avaliar o pH dos sabonetes infantis&#44; antibacterianos e sindets habitualmente usados no banho de crian&#231;as e beb&#234;s&#44; a fim de verificar se esse &#233; ligeiramente &#225;cido e&#44; portanto&#44; condizente com a manuten&#231;&#227;o do manto lip&#237;dico e da fun&#231;&#227;o de barreira&#46; E&#44; secundariamente&#44; verificar se h&#225; nos r&#243;tulos desses produtos informa&#231;&#227;o acerca do seu pH&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Material e m&#233;todos</span><p id="par0040" class="elsevierStylePara elsevierViewall">Estudo observacional&#44; anal&#237;tico&#44; transversal e quantitativo&#46; Foram obtidos produtos de todas as marcas de sabonetes &#40;l&#237;quidos ou em barra&#41; infantis&#44; antibacterianos e sindets encontrados nos postos de venda &#40;supermercados&#44; farm&#225;cias e lojas de cosm&#233;ticos&#41; situados em um raio de 7<span class="elsevierStyleHsp" style=""></span>km do Hospital de Cl&#237;nicas&#44; na regi&#227;o central de Curitiba&#46; Essas amostras foram adquiridas com verba das pr&#243;prias pesquisadoras&#44; de modo a evitar qualquer conflito de interesse&#46; Foram analisados 90 sabonetes &#40;62 em barra e 28 l&#237;quidos&#41;&#44; divididos em tr&#234;s categorias&#44; 67 infantis&#44; 17 antibacterianos e 6 sindets&#46; Esses grupos foram ainda subdivididos em 5 categorias por faixas de pH&#58; menor do que 5&#59; entre 5 e 5&#44;9&#59; entre 6 e 6&#44;9&#59; entre 7 e 7&#44;9&#59; e acima de 8&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">O pH de todos os sabonetes foi medido com pHmetro<span class="elsevierStyleSup">&#174;</span> &#40;Hanna Instruments&#44; modelo H19321&#44; Texas&#44; EUA&#41; em uma dilui&#231;&#227;o a 1&#37; em &#225;gua destilada &#40;pH<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>9&#44;1&#41;&#46; Foi feita uma compara&#231;&#227;o entre as dilui&#231;&#245;es de 1&#37; e 10&#37; e verificou&#8208;se que os valores do pH se mantiveram os mesmos&#46; Dessa forma&#44; devido &#224; maior facilidade de uso de volumes menores&#44; optou&#8208;se pela dilui&#231;&#227;o a 1&#37;&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Os dados foram armazenados em planilha do Microsoft Excel<span class="elsevierStyleSup">&#174;</span> e avaliados no programa R<span class="elsevierStyleSup">&#174;</span>&#44; vers&#227;o 3&#46;0&#46;2 &#40;Microsoft<span class="elsevierStyleSup">&#174;</span>&#44; Washington&#44; EUA&#41;&#46; As medidas de resumo usadas na estat&#237;stica descritiva foram m&#233;dia&#44; desvio padr&#227;o&#44; mediana&#44; valores m&#237;nimo e m&#225;ximo e frequ&#234;ncias&#44; na depend&#234;ncia do tipo da vari&#225;vel estudada&#46; Aplicou&#8208;se o teste qui&#8208;quadrado de Persons&#47;Yates e o <span class="elsevierStyleItalic">t</span> de Student considerando o n&#237;vel de signific&#226;ncia de 5&#37;&#46; Os testes usados para a estat&#237;stica inferencial &#40;compara&#231;&#227;o entre os dados&#41; foram o de Wilcoxon&#8208;Mann&#8208;Whitney&#44; exato de Fisher e o de Kruskal&#8208;Wallis&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">O trabalho foi dispensado da aprova&#231;&#227;o pelo comit&#234; de &#233;tica por n&#227;o envolver seres humanos&#44; apenas a an&#225;lise bioqu&#237;mica dos sabonetes&#46; Parecer n<span class="elsevierStyleSup">o</span> 064&#46;2012&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="par0060" class="elsevierStylePara elsevierViewall">O pH dos sabonetes variou de 4&#44;4 a 11&#44;5&#44; com uma mediana de 10&#44;7&#46; Dois &#40;2&#44;2&#37;&#41; tinham pH menor do que 5&#44; oito &#40;8&#44;8&#37;&#41; entre 5 e 5&#44;9&#44; nove &#40;10&#37;&#41; entre 6 e 6&#44;9&#44; dez &#40;11&#44;1&#37;&#41; entre 7 e 7&#44;9 e 61 &#40;67&#44;7&#37;&#41; maior do que 8&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">No grupo de sabonetes infantis&#44; 47 eram em barra e 20 eram l&#237;quidos &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46; Apenas um dos sabonetes em barra teve pH abaixo de oito &#40;2&#44;2&#37;&#41;&#46; J&#225; entre os l&#237;quidos&#44; um &#40;5&#37;&#41; apresentou pH&#60; 5&#44;0&#59; tr&#234;s &#40;15&#37;&#41; entre 5&#44;0&#8208;5&#44;9&#59; nove &#40;45&#37;&#41; entre 6&#44;0&#8208;6&#44;9 e sete &#40;35&#37;&#41; entre 7&#44;0&#8208;7&#44;9&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">No grupo de sabonetes antibacterianos&#44; 14 eram em barra e tr&#234;s em apresenta&#231;&#227;o l&#237;quida &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46; Todos os sabonetes em barra &#40;100&#37;&#41; apresentaram pH&#62; 8&#44;0&#59; j&#225; entre os l&#237;quidos&#44; um &#40;33&#44;3&#37;&#41; apresentou pH<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>5&#44;0&#59; um &#40;33&#44;3&#37;&#41; entre 5&#44;0&#8208;5&#44;9 e um &#40;33&#44;3&#37;&#41; &#62;<span class="elsevierStyleHsp" style=""></span>8&#44;0&#46; Apenas dois sabonetes antibacterianos na forma l&#237;quida apresentaram pH pr&#243;ximo do fisiol&#243;gico&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">No grupo de sindets&#44; dois eram em barra e quatro eram l&#237;quidos &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46; Dentre os em barra&#44; um &#40;50&#37;&#41; apresentou pH entre 5&#8208;5&#44;9 e um &#40;50&#37;&#41; &#62;<span class="elsevierStyleHsp" style=""></span>8&#44;0&#59; e entre os l&#237;quidos tr&#234;s &#40;75&#37;&#41; apresentaram pH entre 5&#8208;5&#44;9 e um &#40;25&#37;&#41; entre 7&#8208;7&#44;9&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Quando comparados os valores de pH entre os sabonetes l&#237;quidos e em barra&#44; pelo teste exato de Fischer&#44; houve diferen&#231;a estatisticamente significativa &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;0001&#41;&#44; os l&#237;quidos apresentaram valores menores de pH &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">Quando divididos os sabonetes por categoria&#44; infantil&#44; antibacteriano e sindets&#44; tamb&#233;m foram encontrados valores diferentes de pH entre eles pelo teste de Kruskal&#8208;Wallis &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;0017&#41;&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Usou&#8208;se o teste de compara&#231;&#245;es m&#250;ltiplas &#40;exato de Fischer&#41;&#44; o qual demonstrou que existe diferen&#231;a estatisticamente significativa do pH &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;0032&#41; entre os grupos infantil e sindets e entre os grupos antibacteriano e sindets &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;0002&#41;&#46; Os sindets apresentaram pH significativamente menor quando comparados com os demais &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0095" class="elsevierStylePara elsevierViewall">Apenas dois dos sabonetes analisados apresentavam no r&#243;tulo a indica&#231;&#227;o do pH&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discuss&#227;o</span><p id="par0100" class="elsevierStylePara elsevierViewall">As altera&#231;&#245;es do pH da pele provocadas pelo uso de diferentes tipos de sabonetes j&#225; s&#227;o conhecidas&#46;<a class="elsevierStyleCrossRefs" href="#bib0115"><span class="elsevierStyleSup">1&#44;7&#44;9&#44;12&#44;13</span></a> Tamb&#233;m &#233; conhecido que o pH da pele &#233; ligeiramente &#225;cido e que pHs muito alcalinos podem danificar o manto &#225;cido que atua como uma barreira antibacteriana&#44; bem como desestruturar as lamelas da epiderme&#44; favorecer o ressecamento pela maior perda transepid&#233;rmica de &#225;gua e permitir a entrada de potenciais irritantes e al&#233;rgenos&#46;<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">7&#44;9&#44;12&#44;13</span></a> Isso ocorre porque o sabonete em contato com a &#225;gua sofre uma rea&#231;&#227;o de hidr&#243;lise&#44; libera o &#225;lcali contido nesses produtos e eleva o pH da pele para 10 a 11&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">12</span></a> Com base nos resultados apresentados&#44; observa&#8208;se que os sabonetes na forma l&#237;quida s&#227;o os mais indicados para o uso di&#225;rio&#44; principalmente em crian&#231;as e lactentes&#44; cuja pele &#233; mais sens&#237;vel e delicada&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Tal qual demonstrado em nosso estudo&#44; Volchtchuk et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">12</span></a> em trabalho feito na mesma institui&#231;&#227;o&#44; j&#225; haviam demonstrado diferen&#231;as importantes de pH entre as formas l&#237;quidas e em barra de sabonetes&#44; por&#233;m o estudo avaliou sabonetes tanto de uso adulto quanto infantil&#46; As apresenta&#231;&#245;es em barra apresentavam pH acima de 6&#44; a maioria entre 9 e 10&#46; E dentre as apresenta&#231;&#245;es l&#237;quidas&#44; a maioria demonstrou pH entre 6 e 6&#44;9&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">11</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">Os sindets na forma l&#237;quida t&#234;m o pH mais pr&#243;ximo ao fisiol&#243;gico &#40;aproximadamente 5&#41;&#44; s&#227;o recomendados especialmente para os portadores de doen&#231;as que alteram a barreira cut&#226;nea &#40;como a dermatite at&#243;pica e a ictiose&#41;&#44; ou ainda para as crian&#231;as com pele sens&#237;vel&#46; Nesses indiv&#237;duos&#44; o uso de sabonetes com pH elevado piora a xerose&#44; pode gerar solu&#231;&#245;es de continuidade na pele&#44; que servem de porta para os pat&#243;genos&#46; A a&#231;&#227;o dos sindets se d&#225; de duas maneiras&#58; a primeira &#233; reduz a intera&#231;&#227;o entre os agentes tensoativos e as prote&#237;nas e lip&#237;deos da pele&#59; e a segunda restaura lip&#237;deos e umectantes perdidos durante as lavagens&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">19</span></a> Assim&#44; a pele n&#227;o resseca e permanece hidratada&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Os sabonetes antibacterianos em barra apresentaram os maiores valores de pH de todos os avaliados&#46; Isso demonstra que esses produtos podem ser agressivos para a pele da crian&#231;a e que n&#227;o deveriam ser usados de maneira rotineira&#44; mas apenas em situa&#231;&#245;es espec&#237;ficas e por curtos per&#237;odos&#44; bem como em localiza&#231;&#245;es restritas&#44; e n&#227;o no corpo todo&#44; preferencialmente na forma l&#237;quida&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Verificou&#8208;se que os r&#243;tulos dos sabonetes adquiridos&#44; &#224; exce&#231;&#227;o de um&#44; n&#227;o apresentavam informa&#231;&#245;es relacionadas ao pH do produto&#46; Esse dado tamb&#233;m foi referido no estudo de Tarun et al&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">22</span></a> Observamos que mesmo os que continham express&#245;es como &#8220;pH neutro&#8221;&#44; &#8220;pH balanceado&#8221; ou &#8220;dermatologicamente testado&#8221; apresentavam pH acima da faixa esperada&#46; Dessa forma&#44; conclu&#237;mos que v&#225;rios desses produtos trazem informa&#231;&#245;es que podem confundir o consumidor&#44; uma vez que n&#227;o s&#227;o de conhecimento geral as particularidades da leve acidez do extrato c&#243;rneo e da sua import&#226;ncia para a manuten&#231;&#227;o da fun&#231;&#227;o de barreira da pele&#46; Apenas uma marca &#40;Eucerin barra e l&#237;quido&#44; Eucerin<span class="elsevierStyleSup">&#174;</span>&#44; EUA&#41; continha a especifica&#231;&#227;o do pH na embalagem&#44; o que traz grande dificuldade para a escolha ou indica&#231;&#227;o desses produtos pela popula&#231;&#227;o leiga e pelos profissionais da sa&#250;de&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">A maioria dos sabonetes analisados &#233; produzida e vendida no Brasil&#46; Apesar de alguns deles representarem marcas de renome internacional&#44; n&#227;o podemos afirmar que sua composi&#231;&#227;o qu&#237;mica e&#44; consequentemente&#44; seu pH sejam o mesmo em todo o mundo&#46; No entanto&#44; por termos escolhido marcas de produtos que est&#227;o tamb&#233;m dispon&#237;veis em outros pa&#237;ses&#44; em estabelecimentos de f&#225;cil acesso e popularidade&#44; e&#44; ainda&#44; por termos adquirido a maior quantidade de marcas poss&#237;vel&#44; acreditamos que nossos resultados podem ser extrapolados para outras cidades do Brasil e de outras regi&#245;es do mundo&#44; devem ser corroborados por estudos nesses locais&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Este trabalho salienta a inadequa&#231;&#227;o do pH de diversos produtos infantis livremente dispon&#237;veis em postos de venda&#46; Pediatras&#44; pais e cuidadores devem estar atentos &#224;s caracter&#237;sticas dos produtos usados na faixa et&#225;ria pedi&#225;trica&#44; alguns podem at&#233;&#44; causar danos &#224; pele de crian&#231;as e rec&#233;m&#8208;nascidos&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">Com base nisso&#44; seria importante que os &#243;rg&#227;os de vigil&#226;ncia que normatizam a libera&#231;&#227;o de produtos para uso infantil estabelecessem crit&#233;rios mais r&#237;gidos para a sua venda&#44; bem como para as informa&#231;&#245;es que deveriam constar em suas embalagens&#44; entre elas o pH do produto&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conflitos de interesse</span><p id="par0140" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
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          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec665343"
          "palabras" => array:5 [
            0 => "Hydrogen&#8208;ion concentration"
            1 => "Soaps"
            2 => "Detergents"
            3 => "Anti&#8208;bacterial agents"
            4 => "Childcare"
          ]
        ]
      ]
      "pt" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palavras&#8208;chave"
          "identificador" => "xpalclavsec665344"
          "palabras" => array:5 [
            0 => "Concentra&#231;&#227;o de &#237;ons de hidrog&#234;nio"
            1 => "Sab&#245;es"
            2 => "Detergentes"
            3 => "Antibacterianos"
            4 => "Cuidado da crian&#231;a"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To evaluate the pH value of children&#39;s antibacterial soaps and syndets used in children&#39;s baths and verify whether there is information regarding pH on the product label&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Quantitative&#44; cross&#8208;sectional&#44; analytical observational study that included ninety soap samples&#44; both in bar and liquid presentations&#44; as follows&#58; 67 children&#39;s soap &#40;group 1&#41;&#44; 17 antibacterial soaps &#40;group 2&#41;&#44; and six syndets &#40;group 3&#41;&#46; Each sample had its pH measured after 1&#37; dilution&#46; In addition to descriptive statistics&#44; the Pearson&#8208;Yates chi&#8208;squared test and Student&#39;s <span class="elsevierStyleItalic">t</span>&#8208;tests were applied&#44; considering the minimal significance level of 5&#37;&#46; The Wilcoxon&#8208;Mann&#8208;Whitney test&#44; Fisher&#39;s exact test&#44; and the Kruskal&#8208;Wallis test were used for inferential statistics&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The pH levels varied considerably between liquid and bar presentations&#44; with lower levels &#40;4&#46;4 to 7&#46;9&#41; found for the liquids &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; Syndets showed pH levels close to the ideal &#40;slightly acid&#41; and the antibacterial soaps showed the highest pH levels &#40;up to 11&#46;34&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; Only two of the soaps included in the study had information about their pH levels on the product packaging&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Knowledge of the pH of children&#39;s soap by doctors and users is important&#44; considering the great pH variability found in this study&#46; Moreover&#44; liquid soaps&#44; and especially syndets&#44; are the most recommended for the sensitive skin of neonates and infants&#44; in order to guarantee skin barrier efficacy&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objective"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Methods"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusions"
          ]
        ]
      ]
      "pt" => array:3 [
        "titulo" => "Resumo"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivos</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Avaliar o pH dos sabonetes infantis&#44; antibacterianos e sindets &#40;<span class="elsevierStyleItalic">syntetic detergents</span>&#41; habitualmente usados em crian&#231;as&#44; bem como verificar se h&#225; no r&#243;tulo desses produtos informa&#231;&#227;o sobre seu pH&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudo observacional&#44; anal&#237;tico&#44; transversal e quantitativo&#44; que incluiu 90 sabonetes nas apresenta&#231;&#245;es em barra e l&#237;quida&#44; 67 infantis &#40;grupo 1&#41;&#44; 17 antibacterianos &#40;grupo 2&#41; e 6 sindets &#40;grupo 3&#41;&#46; Procedeu&#8208;se &#224; mensura&#231;&#227;o do pH das amostras ap&#243;s dilui&#231;&#227;o a 1&#37;&#46; Al&#233;m da estat&#237;stica descritiva&#44; foram usados os testes de qui&#8208;quadrado Persons&#47;Yates e <span class="elsevierStyleItalic">t</span> de Student&#44; com n&#237;vel de signific&#226;ncia m&#237;nimo de 5&#37;&#46; Para a estat&#237;stica inferencial&#44; foram usados os testes de Wilcoxon&#8208;Mann&#8208;Whitney&#44; exato de Fisher e Kruskal&#8208;Wallis&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">O pH variou consideravelmente entre as formas l&#237;quida e em barra&#44; com pHs menores &#40;de 4&#44;4 a 7&#44;9&#41; nos l&#237;quidos &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41;&#46; Os sindets mostraram pHs pr&#243;ximos ao ideal &#40;levemente &#225;cidos&#41; e os antibacterianos apresentaram os maiores pHs &#40;at&#233; 11&#44;34&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; Apenas dois dos sabonetes analisados apresentavam no r&#243;tulo a indica&#231;&#227;o do pH&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#245;es</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A observa&#231;&#227;o do pH dos sabonetes infantis pelos m&#233;dicos e usu&#225;rios &#233; importante&#44; haja vista a grande variabilidade de valores de pH encontrados&#46; Al&#233;m disso&#44; os sabonetes l&#237;quidos&#44; e especialmente os sindets&#44; s&#227;o os mais recomendados para uso em rec&#233;m&#8208;nascidos e lactentes com pele sens&#237;vel&#44; de forma a garantir a efic&#225;cia da barreira cut&#226;nea&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Objetivos"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "M&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclus&#245;es"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Como citar este artigo&#58; Mendes BR&#44; Shimabukuro DM&#44; Uber M&#44; Abagge KT&#46; Critical assessment of the pH of children&#39;s soap&#46; J Pediatr &#40;Rio J&#41;&#46; 2016&#59;92&#58;290&#8211;5&#46;</p>"
      ]
    ]
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      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figura 1"
        "tipo" => "MULTIMEDIAFIGURA"
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        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 888
            "Ancho" => 1601
            "Tamanyo" => 45323
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        ]
        "descripcion" => array:1 [
          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Varia&#231;&#227;o do potencial hidrogeni&#244;nico &#40;pH&#41; conforme a apresenta&#231;&#227;o dos sabonetes &#40;l&#237;quido e barra&#41; n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>90&#46;</p>"
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        "identificador" => "fig0010"
        "etiqueta" => "Figura 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 868
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        ]
        "descripcion" => array:1 [
          "pt" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Varia&#231;&#227;o do potencial hidrogeni&#244;nico &#40;pH&#41; conforme o grupo dos sabonetes &#40;infantil&#44; antibacteriano ou sindets&#41; n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>90&#46;</p>"
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        "identificador" => "tbl0005"
        "etiqueta" => "Tabela 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
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            "identificador" => "at1"
            "detalle" => "Tabela "
            "rol" => "short"
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        ]
        "tabla" => array:1 [
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              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">pH&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sabonetes infantis em barra</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baruel Xuxinha amarelo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;72&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baruel Xuxinha camomila&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baruel Xuxinha lavanda&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Biocrema The Flintstone&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Baby Boti&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;66&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Sophie Fantasy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Sophie Jeans&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;74&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Sophie Magic&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Spul&#243;kis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cetrilan suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cremer Disney&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cremer Disney Princesas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Davene Beb&#234; vida com extrato natural de aveia e glicerina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;83&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dove baby&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;61&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dove baby da cabe&#231;a aos p&#233;s&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;88&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Galderma Proderm&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Granado Glicerina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;62&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Granado Glicerina Erva doce&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Granado Lavanda&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Ch&#225; de camomila&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Extra suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;77&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Toque de am&#234;ndoas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;73&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hydrata Cuidado perfumado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;99&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hydratta Beb&#234; cuidado suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;59&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hydratta Cuidado delicado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Baby&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Hora de brincar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s &#211;leo de am&#234;ndoas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;79&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Milk&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Hora do sono&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muriel Baby Menina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muriel Baby Menino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Cuca fresca glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;72&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Mam&#227;e e Beb&#234; com extrato de Passiflora&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Natur&#233; Bolol&#244;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Natur&#233; Mistureba&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nazca Acqua Kids Extrato de ma&#231;&#227; e Camomila&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nazca Acqua Kids Pele delicada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;55&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nazca Acqua Kids Cheirinho de erva doce e hortel&#227;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom Camomila e erva cidreira&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom Glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;44&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom Leite e Mel&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom Lo&#231;&#227;o hidratante&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;85&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom &#211;leo de am&#234;ndoas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;97&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Topz Tom &#38; Jerry Limpeza Suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sabonetes infantis liquidos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Avon Baby Calming&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Beb&#234; natureza Extrato de algod&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Sophie&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;94&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Baby Boti&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;76&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cremer Disney&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dove baby da cabe&#231;a aos p&#233;s&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;48&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fischer Price&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;45&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fofo Glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;44&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Galinha Pintadinha Extrato de Algod&#227;o e glicerina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;52&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Giovanna Baby Orange com Giby Care&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Granado Glicerina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;98&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Turma da M&#244;nica Cream Oil&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Turma da M&#244;nica Extra suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Hora de Brincar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Baby rec&#233;m&#8208;nascido&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muriel Baby Menina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muriel Baby Menino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Mam&#227;e e Beb&#234; Glicerina com &#243;leo de passiflora&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;83&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Panvel Baby Club&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Patati Patata Extrato de Aloe Vera&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sabonetes antibacterianos em barra</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dettol Cool&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dettol Cuidado Di&#225;rio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dettol Suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Aveia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Care&#38;Clinical 10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Cream&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Fresh&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Total&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Cream&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Erva doce&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Limpeza profunda&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex &#212;mega 3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Pr&#243;polis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;93&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;91&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dettol original&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;40&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;90&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;50&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eucerin Ph5 Syndet&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;81&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>La Roche Posay Lipikar Surgras&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sindets l&#237;quidos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eucerin Pele Sens&#237;vel pH5 Syndet&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>La Roche Posay Lipikar Surgras&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cetaphil Restoraderm&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;93&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fisiogel Sabonete L&#237;quido Hidratante&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "pt" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Sabonetes de acordo com o grupo&#44; a apresenta&#231;&#227;o e seus respectivos potenciais hidrogeni&#244;nicos &#40;pH&#41;</p>"
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      "titulo" => "Refer&#234;ncias"
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        0 => array:2 [
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                            0 => "G&#46;N&#46; Stamatas"
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                          "etal" => false
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                        "paginaInicial" => "2"
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                        "editorial" => "J&#46; Johnson Editor"
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Critical assessment of the pH of children's soap
Avaliação crítica do pH dos sabonetes infantis
Bruna Rafaela Mendesa, Danielle Midori Shimabukuroa, Marjorie Ubera, Kerstin Taniguchi Abaggeb,
Autor para correspondência
kerstinabagge@gmail.com

Autor para correspondência.
a Universidade Federal do Paraná (UFPR), Curitiba, PR, Brasil
b Unidade de Dermatologia Pediátrica, Departamento de Pediatria, Hospital de Clínicas, Curitiba, PR, Brasil
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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Varia&#231;&#227;o do potencial hidrogeni&#244;nico &#40;pH&#41; conforme a apresenta&#231;&#227;o dos sabonetes &#40;l&#237;quido e barra&#41; n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>90&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introdu&#231;&#227;o</span><p id="par0005" class="elsevierStylePara elsevierViewall">A pele do rec&#233;m&#8208;nascido &#40;RN&#41; exerce fun&#231;&#245;es indispens&#225;veis ao seu desenvolvimento&#58; promove prote&#231;&#227;o por barreira&#44;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">1</span></a> auxilia a termorregula&#231;&#227;o&#44; a troca gasosa&#44; a manuten&#231;&#227;o da hidrata&#231;&#227;o e contribui com a imunidade inata&#46;<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">2</span></a> Al&#233;m disso&#44; seu pH levemente &#225;cido fornece uma prote&#231;&#227;o adicional contra pat&#243;genos&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">1</span></a> A ruptura dessa barreira natural permite que microrganismos oportunistas afetem o RN com dissemina&#231;&#227;o na corrente sangu&#237;nea&#44; principalmente em prematuros&#44; devido &#224; imaturidade do sistema imunol&#243;gico&#46;<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">3</span></a> Estudos indicam que a pele do lactente continua a se desenvolver por at&#233; 12 meses ap&#243;s o nascimento<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">4&#44;5</span></a> e difere da pele do adulto em v&#225;rios aspectos&#44; como composi&#231;&#227;o&#44; estrutura&#44; fun&#231;&#227;o e suscetibilidade a infec&#231;&#245;es&#46;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">4&#44;6&#44;7</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">O potencial hidrogeni&#244;nico &#40;pH&#41; ligeiramente &#225;cido da pele &#233; um importante fator de prote&#231;&#227;o contra microrganismos &#8211; &#233; essencial para a matura&#231;&#227;o da barreira epid&#233;rmica e para os processos de repara&#231;&#227;o&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">8</span></a> Em adultos e adolescentes&#44; o pH da pele &#233; menor do que 5 &#40;pH<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>5&#41;&#46; J&#225; na pele mais fina&#44; especialmente em prematuros&#44; o pH tende ao neutro&#44; resulta em significativa perda da defesa contra a prolifera&#231;&#227;o microbiana e tamb&#233;m maior perda transepid&#233;rmica de &#225;gua&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> Ao nascimento&#44; o RN a termo tem um pH cut&#226;neo que varia de 6&#44;3 a 7&#44;5&#46;<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">10&#44;11</span></a> Dentro das duas primeiras semanas de vida&#44; o pH cai para aproximadamente 5&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">11</span></a> Entre a segunda e quarta semana de vida o pH torna&#8208;se gradativamente &#225;cido&#44; varia entre 4&#44;2 a 5&#44;9&#44; depende da &#225;rea do corpo&#44; prevalecem valores maiores nas axilas&#44; na regi&#227;o genital e na interdigital&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">12</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">O banho &#233; um momento de descontra&#231;&#227;o e de intera&#231;&#227;o m&#227;e e filho&#44; al&#233;m de indispens&#225;vel para a manuten&#231;&#227;o da higiene e sa&#250;de da pele&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">13</span></a> O banho mant&#233;m a pele livre de subst&#226;ncias irritantes &#40;saliva&#44; secre&#231;&#245;es nasais&#44; urina&#44; fezes e enzimas fecais&#41;&#44; p&#243; e germes&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">1</span></a> Segundo a Organiza&#231;&#227;o Mundial de Sa&#250;de &#40;OMS&#41;&#44; &#233; recomendado que o primeiro banho seja dado seis horas ap&#243;s o parto&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> Sugeriu&#8208;se que o banho apenas com &#225;gua fosse o m&#233;todo menos nocivo de limpeza do RN&#44; foi adotado nos protocolos nacionais de cuidados p&#243;s&#8208;natais em muitos pa&#237;ses&#44; dentre eles a Inglaterra&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> Entretanto&#44; a capacidade de tamponamento da &#225;gua tem sido questionada&#44; j&#225; que ela pode aumentar o pH da pele de 5&#44;5 para 7&#44;5&#46; Al&#233;m disso&#44; o emprego isolado de &#225;gua foi identificado como um agente de limpeza inefetivo&#44; j&#225; que n&#227;o remove subst&#226;ncias oleosas como fezes e sebo&#46;<a class="elsevierStyleCrossRefs" href="#bib0180"><span class="elsevierStyleSup">14&#44;15</span></a> Os protocolos americanos recomendam o uso de &#225;gua pot&#225;vel morna&#44; com a op&#231;&#227;o de associar um produto de limpeza suave que apresente pH fisiologicamente adequado &#40;5&#44;5 a 7&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">14</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Acredita&#8208;se que o emprego repetido dos agentes de limpeza pode alterar o pH da superf&#237;cie da pele em longo prazo&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">12</span></a> Os sabonetes tradicionais t&#234;m pH alcalino&#44; que pode destruir a camada lip&#237;dica da pele&#44;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> elevar o pH da pele acima de 8 e levar a ressecamento e irrita&#231;&#227;o&#46;<a class="elsevierStyleCrossRefs" href="#bib0170"><span class="elsevierStyleSup">12&#44;14&#44;16&#8211;19</span></a> Um pH de 7&#44;5 &#233; capaz de aumentar a atividade das proteases cut&#226;neas e inibir a s&#237;ntese da lamela lip&#237;dica e levar a um colapso da barreira cut&#226;nea&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">14</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Os sindets s&#227;o formulados a partir de tensoativos sint&#233;ticos que t&#234;m bom efeito detergente&#44; pH neutro ou ligeiramente &#225;cido e provocam menos irrita&#231;&#227;o&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">9</span></a> Estudos demonstram que o banho com esse tipo de sabonete &#233; compar&#225;vel ao banho somente com &#225;gua ou at&#233; superior a ele&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">20</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Um bom produto de limpeza para os RN deve ter pH pr&#243;ximo de 5&#44;5 e algum tamp&#227;o com capacidade para manter o pH pr&#243;ximo a isso&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">14</span></a> As ind&#250;strias de cosm&#233;ticos colocam no mercado uma grande variedade desses produtos e classificam&#8208;nos como &#8220;suaves&#8221;&#46; No entanto&#44; n&#227;o existe um crit&#233;rio internacional para estabelecer suavidade em agentes de limpeza e geralmente v&#225;rios produtos destinados &#224; peles sens&#237;veis apresentam efeitos irritativos significantes&#46;<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">21</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Assim&#44; o principal objetivo deste estudo foi avaliar o pH dos sabonetes infantis&#44; antibacterianos e sindets habitualmente usados no banho de crian&#231;as e beb&#234;s&#44; a fim de verificar se esse &#233; ligeiramente &#225;cido e&#44; portanto&#44; condizente com a manuten&#231;&#227;o do manto lip&#237;dico e da fun&#231;&#227;o de barreira&#46; E&#44; secundariamente&#44; verificar se h&#225; nos r&#243;tulos desses produtos informa&#231;&#227;o acerca do seu pH&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Material e m&#233;todos</span><p id="par0040" class="elsevierStylePara elsevierViewall">Estudo observacional&#44; anal&#237;tico&#44; transversal e quantitativo&#46; Foram obtidos produtos de todas as marcas de sabonetes &#40;l&#237;quidos ou em barra&#41; infantis&#44; antibacterianos e sindets encontrados nos postos de venda &#40;supermercados&#44; farm&#225;cias e lojas de cosm&#233;ticos&#41; situados em um raio de 7<span class="elsevierStyleHsp" style=""></span>km do Hospital de Cl&#237;nicas&#44; na regi&#227;o central de Curitiba&#46; Essas amostras foram adquiridas com verba das pr&#243;prias pesquisadoras&#44; de modo a evitar qualquer conflito de interesse&#46; Foram analisados 90 sabonetes &#40;62 em barra e 28 l&#237;quidos&#41;&#44; divididos em tr&#234;s categorias&#44; 67 infantis&#44; 17 antibacterianos e 6 sindets&#46; Esses grupos foram ainda subdivididos em 5 categorias por faixas de pH&#58; menor do que 5&#59; entre 5 e 5&#44;9&#59; entre 6 e 6&#44;9&#59; entre 7 e 7&#44;9&#59; e acima de 8&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">O pH de todos os sabonetes foi medido com pHmetro<span class="elsevierStyleSup">&#174;</span> &#40;Hanna Instruments&#44; modelo H19321&#44; Texas&#44; EUA&#41; em uma dilui&#231;&#227;o a 1&#37; em &#225;gua destilada &#40;pH<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>9&#44;1&#41;&#46; Foi feita uma compara&#231;&#227;o entre as dilui&#231;&#245;es de 1&#37; e 10&#37; e verificou&#8208;se que os valores do pH se mantiveram os mesmos&#46; Dessa forma&#44; devido &#224; maior facilidade de uso de volumes menores&#44; optou&#8208;se pela dilui&#231;&#227;o a 1&#37;&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Os dados foram armazenados em planilha do Microsoft Excel<span class="elsevierStyleSup">&#174;</span> e avaliados no programa R<span class="elsevierStyleSup">&#174;</span>&#44; vers&#227;o 3&#46;0&#46;2 &#40;Microsoft<span class="elsevierStyleSup">&#174;</span>&#44; Washington&#44; EUA&#41;&#46; As medidas de resumo usadas na estat&#237;stica descritiva foram m&#233;dia&#44; desvio padr&#227;o&#44; mediana&#44; valores m&#237;nimo e m&#225;ximo e frequ&#234;ncias&#44; na depend&#234;ncia do tipo da vari&#225;vel estudada&#46; Aplicou&#8208;se o teste qui&#8208;quadrado de Persons&#47;Yates e o <span class="elsevierStyleItalic">t</span> de Student considerando o n&#237;vel de signific&#226;ncia de 5&#37;&#46; Os testes usados para a estat&#237;stica inferencial &#40;compara&#231;&#227;o entre os dados&#41; foram o de Wilcoxon&#8208;Mann&#8208;Whitney&#44; exato de Fisher e o de Kruskal&#8208;Wallis&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">O trabalho foi dispensado da aprova&#231;&#227;o pelo comit&#234; de &#233;tica por n&#227;o envolver seres humanos&#44; apenas a an&#225;lise bioqu&#237;mica dos sabonetes&#46; Parecer n<span class="elsevierStyleSup">o</span> 064&#46;2012&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="par0060" class="elsevierStylePara elsevierViewall">O pH dos sabonetes variou de 4&#44;4 a 11&#44;5&#44; com uma mediana de 10&#44;7&#46; Dois &#40;2&#44;2&#37;&#41; tinham pH menor do que 5&#44; oito &#40;8&#44;8&#37;&#41; entre 5 e 5&#44;9&#44; nove &#40;10&#37;&#41; entre 6 e 6&#44;9&#44; dez &#40;11&#44;1&#37;&#41; entre 7 e 7&#44;9 e 61 &#40;67&#44;7&#37;&#41; maior do que 8&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">No grupo de sabonetes infantis&#44; 47 eram em barra e 20 eram l&#237;quidos &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46; Apenas um dos sabonetes em barra teve pH abaixo de oito &#40;2&#44;2&#37;&#41;&#46; J&#225; entre os l&#237;quidos&#44; um &#40;5&#37;&#41; apresentou pH&#60; 5&#44;0&#59; tr&#234;s &#40;15&#37;&#41; entre 5&#44;0&#8208;5&#44;9&#59; nove &#40;45&#37;&#41; entre 6&#44;0&#8208;6&#44;9 e sete &#40;35&#37;&#41; entre 7&#44;0&#8208;7&#44;9&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">No grupo de sabonetes antibacterianos&#44; 14 eram em barra e tr&#234;s em apresenta&#231;&#227;o l&#237;quida &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46; Todos os sabonetes em barra &#40;100&#37;&#41; apresentaram pH&#62; 8&#44;0&#59; j&#225; entre os l&#237;quidos&#44; um &#40;33&#44;3&#37;&#41; apresentou pH<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>5&#44;0&#59; um &#40;33&#44;3&#37;&#41; entre 5&#44;0&#8208;5&#44;9 e um &#40;33&#44;3&#37;&#41; &#62;<span class="elsevierStyleHsp" style=""></span>8&#44;0&#46; Apenas dois sabonetes antibacterianos na forma l&#237;quida apresentaram pH pr&#243;ximo do fisiol&#243;gico&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">No grupo de sindets&#44; dois eram em barra e quatro eram l&#237;quidos &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#41;&#46; Dentre os em barra&#44; um &#40;50&#37;&#41; apresentou pH entre 5&#8208;5&#44;9 e um &#40;50&#37;&#41; &#62;<span class="elsevierStyleHsp" style=""></span>8&#44;0&#59; e entre os l&#237;quidos tr&#234;s &#40;75&#37;&#41; apresentaram pH entre 5&#8208;5&#44;9 e um &#40;25&#37;&#41; entre 7&#8208;7&#44;9&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Quando comparados os valores de pH entre os sabonetes l&#237;quidos e em barra&#44; pelo teste exato de Fischer&#44; houve diferen&#231;a estatisticamente significativa &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;0001&#41;&#44; os l&#237;quidos apresentaram valores menores de pH &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">Quando divididos os sabonetes por categoria&#44; infantil&#44; antibacteriano e sindets&#44; tamb&#233;m foram encontrados valores diferentes de pH entre eles pelo teste de Kruskal&#8208;Wallis &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;0017&#41;&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Usou&#8208;se o teste de compara&#231;&#245;es m&#250;ltiplas &#40;exato de Fischer&#41;&#44; o qual demonstrou que existe diferen&#231;a estatisticamente significativa do pH &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;0032&#41; entre os grupos infantil e sindets e entre os grupos antibacteriano e sindets &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;0002&#41;&#46; Os sindets apresentaram pH significativamente menor quando comparados com os demais &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0095" class="elsevierStylePara elsevierViewall">Apenas dois dos sabonetes analisados apresentavam no r&#243;tulo a indica&#231;&#227;o do pH&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discuss&#227;o</span><p id="par0100" class="elsevierStylePara elsevierViewall">As altera&#231;&#245;es do pH da pele provocadas pelo uso de diferentes tipos de sabonetes j&#225; s&#227;o conhecidas&#46;<a class="elsevierStyleCrossRefs" href="#bib0115"><span class="elsevierStyleSup">1&#44;7&#44;9&#44;12&#44;13</span></a> Tamb&#233;m &#233; conhecido que o pH da pele &#233; ligeiramente &#225;cido e que pHs muito alcalinos podem danificar o manto &#225;cido que atua como uma barreira antibacteriana&#44; bem como desestruturar as lamelas da epiderme&#44; favorecer o ressecamento pela maior perda transepid&#233;rmica de &#225;gua e permitir a entrada de potenciais irritantes e al&#233;rgenos&#46;<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">7&#44;9&#44;12&#44;13</span></a> Isso ocorre porque o sabonete em contato com a &#225;gua sofre uma rea&#231;&#227;o de hidr&#243;lise&#44; libera o &#225;lcali contido nesses produtos e eleva o pH da pele para 10 a 11&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">12</span></a> Com base nos resultados apresentados&#44; observa&#8208;se que os sabonetes na forma l&#237;quida s&#227;o os mais indicados para o uso di&#225;rio&#44; principalmente em crian&#231;as e lactentes&#44; cuja pele &#233; mais sens&#237;vel e delicada&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Tal qual demonstrado em nosso estudo&#44; Volchtchuk et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">12</span></a> em trabalho feito na mesma institui&#231;&#227;o&#44; j&#225; haviam demonstrado diferen&#231;as importantes de pH entre as formas l&#237;quidas e em barra de sabonetes&#44; por&#233;m o estudo avaliou sabonetes tanto de uso adulto quanto infantil&#46; As apresenta&#231;&#245;es em barra apresentavam pH acima de 6&#44; a maioria entre 9 e 10&#46; E dentre as apresenta&#231;&#245;es l&#237;quidas&#44; a maioria demonstrou pH entre 6 e 6&#44;9&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">11</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">Os sindets na forma l&#237;quida t&#234;m o pH mais pr&#243;ximo ao fisiol&#243;gico &#40;aproximadamente 5&#41;&#44; s&#227;o recomendados especialmente para os portadores de doen&#231;as que alteram a barreira cut&#226;nea &#40;como a dermatite at&#243;pica e a ictiose&#41;&#44; ou ainda para as crian&#231;as com pele sens&#237;vel&#46; Nesses indiv&#237;duos&#44; o uso de sabonetes com pH elevado piora a xerose&#44; pode gerar solu&#231;&#245;es de continuidade na pele&#44; que servem de porta para os pat&#243;genos&#46; A a&#231;&#227;o dos sindets se d&#225; de duas maneiras&#58; a primeira &#233; reduz a intera&#231;&#227;o entre os agentes tensoativos e as prote&#237;nas e lip&#237;deos da pele&#59; e a segunda restaura lip&#237;deos e umectantes perdidos durante as lavagens&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">19</span></a> Assim&#44; a pele n&#227;o resseca e permanece hidratada&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Os sabonetes antibacterianos em barra apresentaram os maiores valores de pH de todos os avaliados&#46; Isso demonstra que esses produtos podem ser agressivos para a pele da crian&#231;a e que n&#227;o deveriam ser usados de maneira rotineira&#44; mas apenas em situa&#231;&#245;es espec&#237;ficas e por curtos per&#237;odos&#44; bem como em localiza&#231;&#245;es restritas&#44; e n&#227;o no corpo todo&#44; preferencialmente na forma l&#237;quida&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Verificou&#8208;se que os r&#243;tulos dos sabonetes adquiridos&#44; &#224; exce&#231;&#227;o de um&#44; n&#227;o apresentavam informa&#231;&#245;es relacionadas ao pH do produto&#46; Esse dado tamb&#233;m foi referido no estudo de Tarun et al&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">22</span></a> Observamos que mesmo os que continham express&#245;es como &#8220;pH neutro&#8221;&#44; &#8220;pH balanceado&#8221; ou &#8220;dermatologicamente testado&#8221; apresentavam pH acima da faixa esperada&#46; Dessa forma&#44; conclu&#237;mos que v&#225;rios desses produtos trazem informa&#231;&#245;es que podem confundir o consumidor&#44; uma vez que n&#227;o s&#227;o de conhecimento geral as particularidades da leve acidez do extrato c&#243;rneo e da sua import&#226;ncia para a manuten&#231;&#227;o da fun&#231;&#227;o de barreira da pele&#46; Apenas uma marca &#40;Eucerin barra e l&#237;quido&#44; Eucerin<span class="elsevierStyleSup">&#174;</span>&#44; EUA&#41; continha a especifica&#231;&#227;o do pH na embalagem&#44; o que traz grande dificuldade para a escolha ou indica&#231;&#227;o desses produtos pela popula&#231;&#227;o leiga e pelos profissionais da sa&#250;de&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">A maioria dos sabonetes analisados &#233; produzida e vendida no Brasil&#46; Apesar de alguns deles representarem marcas de renome internacional&#44; n&#227;o podemos afirmar que sua composi&#231;&#227;o qu&#237;mica e&#44; consequentemente&#44; seu pH sejam o mesmo em todo o mundo&#46; No entanto&#44; por termos escolhido marcas de produtos que est&#227;o tamb&#233;m dispon&#237;veis em outros pa&#237;ses&#44; em estabelecimentos de f&#225;cil acesso e popularidade&#44; e&#44; ainda&#44; por termos adquirido a maior quantidade de marcas poss&#237;vel&#44; acreditamos que nossos resultados podem ser extrapolados para outras cidades do Brasil e de outras regi&#245;es do mundo&#44; devem ser corroborados por estudos nesses locais&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Este trabalho salienta a inadequa&#231;&#227;o do pH de diversos produtos infantis livremente dispon&#237;veis em postos de venda&#46; Pediatras&#44; pais e cuidadores devem estar atentos &#224;s caracter&#237;sticas dos produtos usados na faixa et&#225;ria pedi&#225;trica&#44; alguns podem at&#233;&#44; causar danos &#224; pele de crian&#231;as e rec&#233;m&#8208;nascidos&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">Com base nisso&#44; seria importante que os &#243;rg&#227;os de vigil&#226;ncia que normatizam a libera&#231;&#227;o de produtos para uso infantil estabelecessem crit&#233;rios mais r&#237;gidos para a sua venda&#44; bem como para as informa&#231;&#245;es que deveriam constar em suas embalagens&#44; entre elas o pH do produto&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conflitos de interesse</span><p id="par0140" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
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            0 => "Hydrogen&#8208;ion concentration"
            1 => "Soaps"
            2 => "Detergents"
            3 => "Anti&#8208;bacterial agents"
            4 => "Childcare"
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          "palabras" => array:5 [
            0 => "Concentra&#231;&#227;o de &#237;ons de hidrog&#234;nio"
            1 => "Sab&#245;es"
            2 => "Detergentes"
            3 => "Antibacterianos"
            4 => "Cuidado da crian&#231;a"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To evaluate the pH value of children&#39;s antibacterial soaps and syndets used in children&#39;s baths and verify whether there is information regarding pH on the product label&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Quantitative&#44; cross&#8208;sectional&#44; analytical observational study that included ninety soap samples&#44; both in bar and liquid presentations&#44; as follows&#58; 67 children&#39;s soap &#40;group 1&#41;&#44; 17 antibacterial soaps &#40;group 2&#41;&#44; and six syndets &#40;group 3&#41;&#46; Each sample had its pH measured after 1&#37; dilution&#46; In addition to descriptive statistics&#44; the Pearson&#8208;Yates chi&#8208;squared test and Student&#39;s <span class="elsevierStyleItalic">t</span>&#8208;tests were applied&#44; considering the minimal significance level of 5&#37;&#46; The Wilcoxon&#8208;Mann&#8208;Whitney test&#44; Fisher&#39;s exact test&#44; and the Kruskal&#8208;Wallis test were used for inferential statistics&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The pH levels varied considerably between liquid and bar presentations&#44; with lower levels &#40;4&#46;4 to 7&#46;9&#41; found for the liquids &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; Syndets showed pH levels close to the ideal &#40;slightly acid&#41; and the antibacterial soaps showed the highest pH levels &#40;up to 11&#46;34&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; Only two of the soaps included in the study had information about their pH levels on the product packaging&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Knowledge of the pH of children&#39;s soap by doctors and users is important&#44; considering the great pH variability found in this study&#46; Moreover&#44; liquid soaps&#44; and especially syndets&#44; are the most recommended for the sensitive skin of neonates and infants&#44; in order to guarantee skin barrier efficacy&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivos</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Avaliar o pH dos sabonetes infantis&#44; antibacterianos e sindets &#40;<span class="elsevierStyleItalic">syntetic detergents</span>&#41; habitualmente usados em crian&#231;as&#44; bem como verificar se h&#225; no r&#243;tulo desses produtos informa&#231;&#227;o sobre seu pH&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudo observacional&#44; anal&#237;tico&#44; transversal e quantitativo&#44; que incluiu 90 sabonetes nas apresenta&#231;&#245;es em barra e l&#237;quida&#44; 67 infantis &#40;grupo 1&#41;&#44; 17 antibacterianos &#40;grupo 2&#41; e 6 sindets &#40;grupo 3&#41;&#46; Procedeu&#8208;se &#224; mensura&#231;&#227;o do pH das amostras ap&#243;s dilui&#231;&#227;o a 1&#37;&#46; Al&#233;m da estat&#237;stica descritiva&#44; foram usados os testes de qui&#8208;quadrado Persons&#47;Yates e <span class="elsevierStyleItalic">t</span> de Student&#44; com n&#237;vel de signific&#226;ncia m&#237;nimo de 5&#37;&#46; Para a estat&#237;stica inferencial&#44; foram usados os testes de Wilcoxon&#8208;Mann&#8208;Whitney&#44; exato de Fisher e Kruskal&#8208;Wallis&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">O pH variou consideravelmente entre as formas l&#237;quida e em barra&#44; com pHs menores &#40;de 4&#44;4 a 7&#44;9&#41; nos l&#237;quidos &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41;&#46; Os sindets mostraram pHs pr&#243;ximos ao ideal &#40;levemente &#225;cidos&#41; e os antibacterianos apresentaram os maiores pHs &#40;at&#233; 11&#44;34&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05&#41;&#46; Apenas dois dos sabonetes analisados apresentavam no r&#243;tulo a indica&#231;&#227;o do pH&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#245;es</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A observa&#231;&#227;o do pH dos sabonetes infantis pelos m&#233;dicos e usu&#225;rios &#233; importante&#44; haja vista a grande variabilidade de valores de pH encontrados&#46; Al&#233;m disso&#44; os sabonetes l&#237;quidos&#44; e especialmente os sindets&#44; s&#227;o os mais recomendados para uso em rec&#233;m&#8208;nascidos e lactentes com pele sens&#237;vel&#44; de forma a garantir a efic&#225;cia da barreira cut&#226;nea&#46;</p></span>"
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            "rol" => "short"
          ]
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          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">pH&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sabonetes infantis em barra</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baruel Xuxinha amarelo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;72&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baruel Xuxinha camomila&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baruel Xuxinha lavanda&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Biocrema The Flintstone&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Baby Boti&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;66&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Sophie Fantasy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Sophie Jeans&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;74&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Sophie Magic&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Spul&#243;kis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cetrilan suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cremer Disney&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cremer Disney Princesas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Davene Beb&#234; vida com extrato natural de aveia e glicerina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;83&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dove baby&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#44;61&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dove baby da cabe&#231;a aos p&#233;s&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;88&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Galderma Proderm&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Granado Glicerina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;62&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Granado Glicerina Erva doce&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Granado Lavanda&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Ch&#225; de camomila&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Extra suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;77&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Toque de am&#234;ndoas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;73&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hydrata Cuidado perfumado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;99&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hydratta Beb&#234; cuidado suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;59&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hydratta Cuidado delicado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Baby&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Hora de brincar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s &#211;leo de am&#234;ndoas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;79&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Milk&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Hora do sono&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muriel Baby Menina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muriel Baby Menino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Cuca fresca glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;72&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Mam&#227;e e Beb&#234; com extrato de Passiflora&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Natur&#233; Bolol&#244;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Natur&#233; Mistureba&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nazca Acqua Kids Extrato de ma&#231;&#227; e Camomila&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nazca Acqua Kids Pele delicada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;55&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nazca Acqua Kids Cheirinho de erva doce e hortel&#227;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom Camomila e erva cidreira&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom Glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;44&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom Leite e Mel&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom Lo&#231;&#227;o hidratante&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;85&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Pom Pom &#211;leo de am&#234;ndoas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;97&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Topz Tom &#38; Jerry Limpeza Suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sabonetes infantis liquidos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Avon Baby Calming&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Beb&#234; natureza Extrato de algod&#227;o&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Sophie&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;94&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Botic&#225;rio Baby Boti&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;76&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cremer Disney&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dove baby da cabe&#231;a aos p&#233;s&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;48&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fischer Price&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;45&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fofo Glicerinado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;44&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Galinha Pintadinha Extrato de Algod&#227;o e glicerina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;52&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Giovanna Baby Orange com Giby Care&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Granado Glicerina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;98&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Turma da M&#244;nica Cream Oil&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Huggies Turma da M&#244;nica Extra suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Hora de Brincar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Johnson&#39;s Baby rec&#233;m&#8208;nascido&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muriel Baby Menina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muriel Baby Menino&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Natura Mam&#227;e e Beb&#234; Glicerina com &#243;leo de passiflora&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;83&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Panvel Baby Club&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Patati Patata Extrato de Aloe Vera&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6&#44;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sabonetes antibacterianos em barra</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dettol Cool&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dettol Cuidado Di&#225;rio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dettol Suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Aveia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Care&#38;Clinical 10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Cream&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Fresh&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy Total&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Cream&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Erva doce&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Limpeza profunda&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex &#212;mega 3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Pr&#243;polis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;93&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex suave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;91&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sabonetes antibacterianos l&#237;quidos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Dettol original&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#44;40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Protex Cream&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;90&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lifebuoy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#44;50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sindets em barra</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eucerin Ph5 Syndet&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;81&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>La Roche Posay Lipikar Surgras&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#44;35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sindets l&#237;quidos</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eucerin Pele Sens&#237;vel pH5 Syndet&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>La Roche Posay Lipikar Surgras&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cetaphil Restoraderm&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#44;93&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Fisiogel Sabonete L&#237;quido Hidratante&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#44;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "pt" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Sabonetes de acordo com o grupo&#44; a apresenta&#231;&#227;o e seus respectivos potenciais hidrogeni&#244;nicos &#40;pH&#41;</p>"
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      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Refer&#234;ncias"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:22 [
            0 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The infant skin barrier&#58; can we preserve&#44; protect&#44; and enhance the barrier&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "L&#46;S&#46; Telofski"
                            1 => "A&#46;P&#46; Morello"
                            2 => "M&#46;C&#46; Correa"
                            3 => "G&#46;N&#46; Stamatas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Res Pract&#46;"
                        "fecha" => "2012"
                        "volumen" => "2012"
                        "paginaInicial" => "1"
                        "paginaFinal" => "18"
                      ]
                    ]
                  ]
                ]
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              "identificador" => "bib0120"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The skin barrier as an innate immune element"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46;M&#46; Elias"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Immunopathol&#46;"
                        "fecha" => "2007"
                        "volumen" => "29"
                        "paginaInicial" => "3"
                        "paginaFinal" => "14"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17621950"
                            "web" => "Medline"
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                ]
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              "identificador" => "bib0125"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk factors and lethality of laboratory&#8208;confirmed bloodstream infection caused by non&#8208;skin contaminant pathogens in neonates"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46;M&#46; Romanelli"
                            1 => "L&#46;M&#46; Anchieta"
                            2 => "M&#46;V&#46; Mour&#227;o"
                            3 => "F&#46;A&#46; Campos"
                            4 => "F&#46;C&#46; Loyola"
                            5 => "P&#46;H&#46; Mour&#227;o"
                          ]
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Informação do artigo
ISSN: 22555536
Idioma original: Português
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