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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introdu&#231;&#227;o</span><p id="par0005" class="elsevierStylePara elsevierViewall">Colestase &#233; uma manifesta&#231;&#227;o comum de doen&#231;a hep&#225;tica em crian&#231;as&#44; que ocorre em cerca de 65&#37; desses pacientes&#46; A doen&#231;a consiste no impedimento do fluxo da bile devido a uma obstru&#231;&#227;o no trato biliar ou um impedimento da absor&#231;&#227;o&#44; conjuga&#231;&#227;o ou excre&#231;&#227;o de &#225;cidos biliares&#46;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">1&#44;2</span></a> A colestase prejudica a situa&#231;&#227;o nutricional dessas crian&#231;as&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">3</span></a> A desnutri&#231;&#227;o leva &#224; morbidez e mortalidade cada vez maiores em pacientes com doen&#231;a hep&#225;tica cr&#244;nica&#46; Barshes et al&#46;<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">4</span></a> relataram que a desnutri&#231;&#227;o no per&#237;odo anterior ao transplante est&#225; associada a maior interna&#231;&#227;o e gastos hospitalares&#46; Al&#233;m disso&#44; Moukarzel et al&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">5</span></a> mostraram uma estreita correla&#231;&#227;o entre situa&#231;&#227;o nutricional e resultados do transplante de f&#237;gado em crian&#231;as&#46; Neste estudo&#44; crian&#231;as com um escore Z abaixo de &#8211;2 desvios padr&#227;o apresentaram uma incid&#234;ncia mais elevada de infec&#231;&#227;o no per&#237;odo posterior ao transplante&#44; mais complica&#231;&#245;es cir&#250;rgicas e mortalidade mais elevada&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Aproximadamente 60&#37; das crian&#231;as com doen&#231;a hep&#225;tica cr&#244;nica est&#227;o abaixo do peso e da altura esperados para sua idade&#46;<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">6&#44;7</span></a> Uma assist&#234;ncia nutricional adequada pode evitar a r&#225;pida progress&#227;o da doen&#231;a de base&#44; com melhoria da fun&#231;&#227;o imune&#46;<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">6&#44;8&#44;9</span></a> A avalia&#231;&#227;o nutricional dessas crian&#231;as &#233; essencial&#44; por&#233;m o peso pode ser superestimado em casos de visceromegalia&#44; ascite e edema perif&#233;rico&#59; portanto&#44; separadamente&#44; essa avalia&#231;&#227;o n&#227;o &#233; um bom par&#226;metro para identificar a desnutri&#231;&#227;o&#46; As medidas mais sens&#237;veis para determinar a situa&#231;&#227;o nutricional na doen&#231;a hep&#225;tica cr&#244;nica s&#227;o a circunfer&#234;ncia do bra&#231;o e a prega cut&#226;nea do tr&#237;ceps&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">10</span></a> Um exame f&#237;sico meticuloso&#44; v&#225;rias medidas f&#237;sicas e antropom&#233;tricas e exames complementares individualizados s&#227;o indispens&#225;veis&#46; Como a desnutri&#231;&#227;o &#233; consequ&#234;ncia da colestase cr&#244;nica&#44; o conhecimento do impacto dessa doen&#231;a em crian&#231;as afetadas poder&#225; auxiliar na recomenda&#231;&#227;o de uma interven&#231;&#227;o nutricional&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">O objetivo deste estudo &#233; avaliar a situa&#231;&#227;o nutricional de crian&#231;as diagnosticadas com colestase acompanhadas na Cl&#237;nica de Hepatologia Pedi&#225;trica de nossa institui&#231;&#227;o e correlacionar a ingest&#227;o de alimentos com a situa&#231;&#227;o nutricional&#46; Al&#233;m disso&#44; os &#237;ndices antropom&#233;tricos s&#227;o comparados em pacientes com e sem cirrose hep&#225;tica e crian&#231;as com e sem icter&#237;cia&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Pacientes e m&#233;todos</span><p id="par0020" class="elsevierStylePara elsevierViewall">Este estudo de s&#233;rie de casos foi feito na Cl&#237;nica de Hepatologia Pedi&#225;trica de nossa institui&#231;&#227;o &#40;Hospital das Cl&#237;nicas&#44; UFMG&#44; Brasil&#41; de janeiro de 2009 a dezembro de 2013&#46; Foram inclu&#237;das crian&#231;as com colestase cl&#237;nica e&#47;ou laboratorial persistente&#46; A colestase persistente foi definida como um aumento da bilirrubina direta &#40;bilirrubina direta acima de 20&#37; da bilirrubina total ou acima de 2<span class="elsevierStyleHsp" style=""></span>mg&#47;dL quando os n&#237;veis est&#227;o acima de 5<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; ou bilirrubina direta acima de 1<span class="elsevierStyleHsp" style=""></span>mg&#47;dL quando o total &#233; inferior a 5<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41; ou aumento da enzima canalicular&#44; gamaglutamiltransferase &#40;GGT&#41;&#44; acima do valor de refer&#234;ncia para a idade&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">11</span></a> Todos os pacientes foram submetidos a bi&#243;psia do f&#237;gado&#44; indicada na avalia&#231;&#227;o inicial do paciente para obter um diagn&#243;stico diferenciado da colestase e&#47;ou durante o curso da doen&#231;a para o monitoramento de achados histopatol&#243;gicos&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">O estudo foi aprovado pelo Comit&#234; de &#201;tica de nossa institui&#231;&#227;o &#40;n&#250;mero de protocolo ETIC 310&#47;08&#41;&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">As medidas antropom&#233;tricas foram peso&#44; estatura ou altura&#44; circunfer&#234;ncia do bra&#231;o &#40;CB&#41;&#44; espessura da prega cut&#226;nea do tr&#237;ceps &#40;TST&#41;&#44; circunfer&#234;ncia muscular do bra&#231;o &#40;CMB&#41; e &#237;ndice de massa corporal &#40;IMC&#41;&#46; As vari&#225;veis analisadas foram&#58; sexo&#44; idade em meses na &#233;poca da avalia&#231;&#227;o cl&#237;nica&#44; classifica&#231;&#227;o em com e sem cirrose &#40;com base na histopatologia&#41;&#44; classifica&#231;&#227;o da cirrose pelos crit&#233;rios de Child&#8208;Pugh&#44; testes de laborat&#243;rio &#40;albumina e bilirrubina&#41; e ingest&#227;o cal&#243;rica por meio do di&#225;rio alimentar de 72 horas&#46; Os dados cl&#237;nicos e laboratoriais foram obtidos na mesma &#233;poca da avalia&#231;&#227;o nutricional&#44; ou seja&#44; em um &#250;nico momento&#46; A ingest&#227;o de alimentos foi registrada durante 72 horas ap&#243;s a avalia&#231;&#227;o nutricional&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">As crian&#231;as com menos de dois anos e com peso at&#233; 16<span class="elsevierStyleHsp" style=""></span>kg foram medidas por um antrop&#244;metro horizontal &#40;R&#233;gua Antropom&#233;trica Pedi&#225;trica&#44; NutriVida<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; Brasil&#41; e pesadas&#44; sem roupas e fralda&#44; em uma balan&#231;a eletr&#244;nica digital calibrada &#40;Balan&#231;a Digital Infantil&#44; Welmy<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; Brasil&#41;&#46; O estadi&#244;metro vertical &#40;Physical NutriVida<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; Brasil&#41; e uma plataforma eletr&#244;nica digital calibrada &#40;Balan&#231;a Digital&#44; Balmak<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; Brasil&#41; foram usados para medir crian&#231;as com mais de dois anos&#46; Os pacientes foram avaliados descal&#231;os e&#44; normalmente&#44; apenas com roupas &#237;ntimas&#46; Todos os equipamentos foram verificados antes de ser usados&#46; Essas medidas foram classificadas com o aux&#237;lio do protocolo Sisvan &#40;Sistema de Vigil&#226;ncia Alimentar e Nutricional&#41; 2008<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">12</span></a> por fase da vida&#44; adaptado da Organiza&#231;&#227;o Mundial de Sa&#250;de 2006&#59;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">13</span></a> os pontos de corte usados tiveram os gr&#225;ficos da OMS como refer&#234;ncia e foram calculados pela vers&#227;o 3&#46;2&#46;2 do Anthro da OMS&#46;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">14</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Uma fita inel&#225;stica foi usada para medir a CBe um plic&#244;metro para a medi&#231;&#227;o do TST&#46; Esses par&#226;metros foram calculados e classificados com base nos padr&#245;es da OMS de acordo com idade e altura&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">15</span></a> As medidas foram feitas no lado direito da crian&#231;a&#46; Os pacientes com menos de dois anos foram avaliados de p&#233;&#44; no colo da m&#227;e ou do tutor&#46; A CB foi medida em um ponto intermedi&#225;rio entre o acr&#244;mio e a borda inferior do olecrano&#46; A TST foi medida na mesma posi&#231;&#227;o da CB&#44; ou seja&#44; no lado posterior do bra&#231;o&#46; A medi&#231;&#227;o foi feita ao longo do eixo longitudinal do membro&#46; Tr&#234;s medidas foram tiradas na mesma posi&#231;&#227;o com uma diferen&#231;a de tr&#234;s segundos entre si e a m&#233;dia dos valores foi calculada para evitar poss&#237;veis erros conforme recomendado pela literatura&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">12</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Os pacientes foram classificados com base no c&#225;lculo do <span class="elsevierStyleItalic">software</span> Anthro<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">14</span></a> da OMS ao usar os seguintes valores&#58; deple&#231;&#227;o grave &#40;menos de 70&#37;&#41;&#44; deple&#231;&#227;o moderada &#40;entre 70&#37; e 80&#37;&#41;&#44; deple&#231;&#227;o leve &#40;entre 80&#37; e 90&#37;&#41;&#44; eutrofia &#40;entre 90&#37; e 110&#37;&#41;&#44; sobrepeso &#40;entre 110&#37; e 120&#37;&#41; e obesidade &#40;mais de 120&#37;&#41;&#46; As f&#243;rmulas para esses c&#225;lculos foram&#58; adequa&#231;&#227;o da CB &#40;&#37;&#41;<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#91;CB obtida &#40;cm&#41; &#247; 50&#176; percentil da CB&#93; x 100&#59; adequa&#231;&#227;o da TST &#40;&#37;&#41;<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#91;TST obtida &#40;cm&#41; &#247; 50&#176; percentil da TST&#93; x 100&#59; CMB &#40;cm&#41;<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>CB &#40;cm&#41; &#8208; 3&#44;14 x TST &#40;cm&#41;&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Os valores de CMB&#44; de acordo com sexo e idade&#44; foram comparados com os valores de refer&#234;ncia do Levantamento Nacional de Exame de Sa&#250;de e Nutri&#231;&#227;o &#40;NHANES&#41;&#44; expressos em tabelas de percentis por Frisancho a partir de um ano de idade&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a> Pacientes com menos de um ano foram exclu&#237;dos desta an&#225;lise devido &#224; aus&#234;ncia de valores de refer&#234;ncia para essa faixa et&#225;ria&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Ap&#243;s uma avalia&#231;&#227;o cl&#237;nica&#44; o cuidador da crian&#231;a relatou todos os alimentos ingeridos pela crian&#231;a por tr&#234;s dias consecutivos&#46; Foram informados o n&#250;mero de dias&#44; o hor&#225;rio&#44; o tipo e a quantidade de comida ingerida pela crian&#231;a&#46; Quanto a crian&#231;as exclusivamente amamentadas&#44; a m&#227;e anotou o hor&#225;rio da amamenta&#231;&#227;o para estimar&#44; de acordo com a idade e o tempo de suc&#231;&#227;o&#44; o volume de leite ingerido pelo neonato&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">O c&#225;lculo da ingest&#227;o de calorias e prote&#237;nas foi feito com o <span class="elsevierStyleItalic">software</span> DietPro&#44; vers&#227;o 4&#46;0 &#40;Agrom&#237;dia Softwares<span class="elsevierStyleSup">&#174;</span>&#44; Minas Gerais&#44; Brasil&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">17</span></a> bem como com base na Tabela de Composi&#231;&#227;o de Alimentos de S&#244;nia Tucunduva<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">18</span></a> e na tabela de medidas caseiras&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">19</span></a> incluindo os macronutrientes carboidrato&#44; prote&#237;na e lip&#237;dio&#46; A seguir&#44; as recomenda&#231;&#245;es di&#225;rias de calorias foram calculadas de acordo com a idade pela Organiza&#231;&#227;o das Na&#231;&#245;es Unidas para Agricultura e Alimenta&#231;&#227;o &#40;FAO&#47;OMS&#47;ONU&#41; 1985&#44; com base na necessidade cal&#243;rica de consumo total de energia mais o crescimento de crian&#231;as amamentadas&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">20</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">Os dados foram analisados pelo Epi Info&#44; vers&#227;o 6&#46;04 &#40;Centro de Controle e Preven&#231;&#227;o de Doen&#231;as&#44; Atlanta&#44; EUA&#41;&#46; As vari&#225;veis cont&#237;nuas com distribui&#231;&#227;o n&#227;o gaussiana foram apresentadas como medianas e intervalo interquartil &#40;IQ do 25&#176; ao 75&#176;&#41; e comparadas com o teste de Kruskal&#8208;Wallis n&#227;o param&#233;trico&#46; A distribui&#231;&#227;o das vari&#225;veis dicot&#244;micas foi comparada pelo teste qui&#8208;quadrado&#44; com corre&#231;&#227;o de Yates&#44; ou pelo teste exato de Fisher bicaudal&#44; caso necess&#225;rio&#46; A probabilidade foi considerada significativa quando inferior a 0&#44;05 &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41;&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="par0070" class="elsevierStylePara elsevierViewall">Foram avaliadas 91 crian&#231;as com diagn&#243;stico inicial de colestase&#46; A idade m&#233;dia era de 12 meses e 52&#44;7&#37; delas eram do sexo masculino&#46; As etiologias de colestase eram&#58; atresia biliar em 31 pacientes &#40;34&#44;1&#37;&#41;&#44; hepatite neonatal idiop&#225;tica em 25 &#40;27&#44;5&#37;&#41;&#44; colestase multifatorial em oito &#40;8&#44;8&#37;&#41;&#44; s&#237;ndrome de Alagille em oito &#40;8&#44;8&#37;&#41;&#44; defici&#234;ncia de alfa&#8208;1&#8208;antitripsina em seis &#40;6&#44;6&#37;&#41;&#44; hipoplasia de vias biliares em quatro &#40;4&#44;4&#37;&#41; e outros diagn&#243;sticos em seis &#40;6&#44;6&#37;&#41;&#59; 25 pacientes &#40;27&#44;5&#37;&#41; apresentaram cirrose no exame histopatol&#243;gico &#40;18 com atresia biliar e sete com hepatite neonatal idiop&#225;tica&#41; e 11 pacientes foram classificados como Child&#8208;Pug A &#40;44&#37;&#41;&#44; 12 como B &#40;48&#37;&#41; e dois como C &#40;8&#37;&#41;&#59; 70 &#40;76&#44;9&#37;&#41; apresentaram icter&#237;cia com n&#237;veis excepcionalmente altos de bilirrubina&#44; GGT e aminotransferase&#44; ao passo que 21 crian&#231;as &#40;23&#44;1&#37;&#41; apresentaram n&#237;veis normais de bilirrubina&#44; sem icter&#237;cia&#44; por&#233;m com aumento dos n&#237;veis de GGT&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Dados cl&#237;nicos&#44; laboratoriais&#44; nutricionais e antropom&#233;tricos dos pacientes s&#227;o apresentados nas <a class="elsevierStyleCrossRefs" href="#tbl0005">tabelas 1 e 2</a>&#46; As seguintes abreviaturas foram usadas&#58; P&#47;I&#58; &#237;ndice peso&#47;idade&#59; A&#47;I&#58; &#237;ndice altura&#47;idade&#59; P&#47;A&#58; &#237;ndice peso&#47;altura&#59; IMC&#58; &#237;ndice de massa corporal&#46; Com rela&#231;&#227;o a alguns dados&#44; marcados com um asterisco&#44; foram usadas a mediana e o intervalo interquartil &#40;IQ 25&#176;&#8208;75&#176;&#41;&#59; com rela&#231;&#227;o ao di&#225;rio alimentar&#44; o c&#225;lculo usado foi registro do di&#225;rio alimentar&#47;recomendado para a idade x 100&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0080" class="elsevierStylePara elsevierViewall">No que diz respeito &#224; ingest&#227;o nutricional&#44; 57&#44;2&#37; dos 91 pacientes estavam 95&#37; abaixo das calorias recomendadas&#44; sem diferen&#231;a estatisticamente significativa entre os com e sem cirrose &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;32&#41; e entre crian&#231;as com e sem icter&#237;cia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;80&#41;&#46; Ao comparar pacientes com ingest&#227;o 95&#37; abaixo do recomendado com os pacientes com deple&#231;&#227;o nutricional&#44; n&#227;o encontramos diferen&#231;a estatisticamente significativa na CB &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;14&#41;&#44; na TST &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;09&#41; e na CMB &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;09&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">A <a class="elsevierStyleCrossRef" href="#tbl0015">tabela 3</a> mostra a classifica&#231;&#227;o nutricional com base em &#237;ndices antropom&#233;tricos em todo o grupo e em pacientes estratificados de acordo com a presen&#231;a de cirrose&#46; N&#227;o houve diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose com rela&#231;&#227;o aos &#237;ndices P&#47;I &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;48&#41; e A&#47;I &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;92&#41;&#44; bem como n&#227;o houve diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose com rela&#231;&#227;o aos &#237;ndices P&#47;A &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;28&#41; e IMC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;07&#41;&#46; Com rela&#231;&#227;o &#224; CB&#44; houve uma diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;006&#41;&#46; Com rela&#231;&#227;o &#224; TST e &#224; CMB&#44; n&#227;o houve uma diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;07 para TST e 83&#44;3&#37; em compara&#231;&#227;o a 66&#44;7&#37; com p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;24 para CMB&#41;&#46; A <a class="elsevierStyleCrossRef" href="#tbl0020">tabela 4</a> apresenta a classifica&#231;&#227;o nutricional com base em &#237;ndices antropom&#233;tricos em todo o grupo e em pacientes estratificados de acordo com a presen&#231;a de icter&#237;cia&#46; Nenhuma diferen&#231;a foi observada na compara&#231;&#227;o entre os dados de crian&#231;as com e sem icter&#237;cia com rela&#231;&#227;o ao &#237;ndice P&#47;I &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;18&#41;&#44; A&#47;I &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;92&#41;&#44; P&#47;A &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;45&#41; e IMC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;07&#41;&#46; No que diz respeito &#224; presen&#231;a de qualquer grau de deple&#231;&#227;o na CB e na TST&#44; pacientes com icter&#237;cia apresentaram frequ&#234;ncia significativamente maior de deple&#231;&#227;o em ambos os par&#226;metros do que os sem icter&#237;cia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;045 e p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#44; respectivamente&#41;&#46; N&#227;o houve diferen&#231;a estatisticamente significativa com rela&#231;&#227;o &#224; CMB &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;08&#41;&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0090" class="elsevierStylePara elsevierViewall">Ao comparar pacientes com deple&#231;&#227;o nutricional por TST com pacientes com baixo peso para a altura ou idade&#44; encontramos uma diferen&#231;a estatisticamente significativa em ambos &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;000&#41;&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">No que diz respeito &#224; avalia&#231;&#227;o da CB&#44; 39 &#40;43&#44;8&#37;&#41; de 89 pacientes apresentaram algum grau de deple&#231;&#227;o&#46; Por outro lado&#44; ao avaliar e comparar com o P&#47;A&#44; observamos que apenas 11 &#40;12&#44;3&#37;&#41; de 89 pacientes apresentaram baixo peso para a altura &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e com o P&#47;I&#44; apenas 28 &#40;31&#44;5&#37;&#41; apresentaram baixo peso para a idade &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;000&#41;&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">Da mesma forma&#44; quando avaliamos a CMB&#44; 32 &#40;71&#44;1&#37;&#41; de 45 pacientes apresentaram algum grau de deple&#231;&#227;o&#44; ao passo que apenas dois &#40;4&#44;4&#37;&#41; apresentaram baixo peso para a altura &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;000&#41; e apenas sete &#40;15&#44;6&#37;&#41; de 45 pacientes apresentaram baixo peso para a idade &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;000&#41;&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discuss&#227;o</span><p id="par0105" class="elsevierStylePara elsevierViewall">A avalia&#231;&#227;o nutricional dessas crian&#231;as &#233; essencial&#44; por&#233;m apresenta diversos desafios&#46; A presen&#231;a de visceromegalia&#44; ascite e edema perif&#233;rico pode limitar o uso do peso&#44; o &#237;ndice mais comum de avalia&#231;&#227;o nutricional&#46; Portanto&#44; um exame f&#237;sico meticuloso&#44; v&#225;rias medidas antropom&#233;tricas e exames complementares individualizados s&#227;o essenciais para uma avalia&#231;&#227;o nutricional confi&#225;vel desses pacientes&#46; As medidas de TST e CB s&#227;o mais confi&#225;veis porque esses par&#226;metros n&#227;o levam em considera&#231;&#227;o o peso e podem ser extremamente importantes na pr&#225;tica cl&#237;nica ao permitir um diagn&#243;stico antecipado de d&#233;ficits nutricionais&#46; A estimativa de dep&#243;sitos de gordura por meio da TST e de conte&#250;do proteico pela CMB e CB s&#227;o dados complementares que permitem a avalia&#231;&#227;o nutricional precisa desses pacientes&#46;<a class="elsevierStyleCrossRefs" href="#bib0140"><span class="elsevierStyleSup">3&#44;21&#44;22</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">Neste estudo&#44; um ter&#231;o dos pacientes mostrou &#237;ndices P&#47;A e A&#47;I com escore Z abaixo de &#8211;2&#46; Considerando o &#237;ndice P&#47;A&#44; apenas 12&#44;1&#37; dos pacientes apresentaram escore Z abaixo de &#8211;2&#59; com rela&#231;&#227;o ao IMC&#44; o percentual foi de 16&#44;5&#37;&#46; Isso mostra que o &#237;ndice P&#47;A sempre deve ser usado em combina&#231;&#227;o com o &#237;ndice A&#47;I&#44; j&#225; que os d&#233;ficits proporcionais no peso e altura n&#227;o s&#227;o identificados nesse primeiro m&#233;todo&#44; e mostra tamb&#233;m que o IMC n&#227;o permite uma boa aferi&#231;&#227;o da composi&#231;&#227;o corporal&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Da mesma forma&#44; em outro estudo brasileiro com 22 crian&#231;as e adolescentes com colestase&#44; 23&#44;8&#37; e 33&#44;3&#37; dos pacientes estavam malnutridos de acordo com os crit&#233;rios de P&#47;I e A&#47;I&#44; respectivamente&#44; e nenhum deles ficou com escore Z abaixo de &#8211;2 com rela&#231;&#227;o ao &#237;ndice P&#47;A&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">23</span></a> A inadequa&#231;&#227;o nutricional foi maior quando os &#237;ndices de CB&#44; TST e CMB foram usados&#46; A CB revelou 43&#44;9&#37; dos pacientes com algum grau de deple&#231;&#227;o&#44; a TST mostrou 46&#44;2&#37; e a CMB&#44; 71&#44;1&#37;&#46; Embora os &#237;ndices P&#47;I e a A&#47;I tenham revelado quase um ter&#231;o de pacientes com deple&#231;&#227;o nutricional&#44; os &#237;ndices CB&#44; TST e CMB mostraram maior frequ&#234;ncia de desnutri&#231;&#227;o&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">A CMB provavelmente mostrou uma propor&#231;&#227;o maior de pacientes com nutri&#231;&#227;o inadequada em compara&#231;&#227;o com a CB e a TST devido &#224; idade dos pacientes avaliados neste estudo&#46; A CMB foi relatada apenas em pacientes acima de um ano&#44; ou seja&#44; com um tempo mais longo de evolu&#231;&#227;o da colestase&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Schneider et al&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">24</span></a> relataram em seu estudo sobre crian&#231;as com cirrose que o &#237;ndice que refletiu melhor o risco nutricional foi a TST&#46; Isso confirma que ela pode medir a massa de gordura corporal e mostrar a extens&#227;o e a gravidade da desnutri&#231;&#227;o&#46; Portanto&#44; essa medida &#233; muito importante na avalia&#231;&#227;o nutricional desses pacientes&#46; Sokol et al&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">25</span></a> enfatizaram a import&#226;ncia das medidas de TST e CB como m&#233;todos mais precisos de avaliar dep&#243;sitos de gordura e teor de prote&#237;na em pacientes com doen&#231;a hep&#225;tica cr&#244;nica&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Com rela&#231;&#227;o aos &#237;ndices de P&#47;I e IMC&#44; ocorre uma falha importante&#44; que pode ser explicada&#44; pelo menos em parte&#44; pelo padr&#227;o cr&#244;nico de comprometimento nutricional observado nesses pacientes quando tanto o peso quanto a altura est&#227;o envolvidos&#46; Isso refor&#231;a que o uso de &#237;ndices antropom&#233;tricos convencionais como P&#47;I&#44; A&#47;I&#44; P&#47;A e IMC pode superestimar a situa&#231;&#227;o nutricional de pacientes com colestase&#44; mesmo quando edema e ascite n&#227;o s&#227;o evidentes&#46; Al&#233;m disso&#44; a visceromegalia contribui para o aumento do peso desses pacientes&#44; o que compromete o uso de &#237;ndices que incluem peso&#46;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">2</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">A inadequa&#231;&#227;o desses &#237;ndices tamb&#233;m pode ser observada ao se compararem pacientes com e sem icter&#237;cia e com e sem cirrose hep&#225;tica&#46; Nenhuma diferen&#231;a estat&#237;stica foi detectada entre esses subgrupos com rela&#231;&#227;o aos &#237;ndices P&#47;I&#44; A&#47;I&#44; P&#47;A ou IMC&#46; Por outro lado&#44; a avalia&#231;&#227;o da CB mostrou uma diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose e entre crian&#231;as com e sem icter&#237;cia&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">A avalia&#231;&#227;o da TST e da CMB n&#227;o apresentou diferen&#231;a estat&#237;stica entre pacientes com e sem cirrose&#46; Isso pode ser explicado pelo fato de que a avalia&#231;&#227;o dos pacientes foi feita em um &#250;nico momento&#46; Em resumo&#44; na maioria dos casos&#44; a desnutri&#231;&#227;o foi detectada apenas quando a avalia&#231;&#227;o n&#227;o estava restrita &#224;s medidas de peso e altura&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">A frequ&#234;ncia de deple&#231;&#227;o nutricional com base na avalia&#231;&#227;o da CB e da TST foi semelhante&#44; o que indica deple&#231;&#227;o semelhante de gordura e massa magra&#46; Esse achado diferiu dos resultados relatados por Cardoso et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> que observaram perda inicial de gordura mais elevada&#46; Essa diferen&#231;a pode ser atribu&#237;da &#224; idade dos pacientes&#44; pois&#44; no estudo de Cardoso et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> os pacientes eram mais novos&#44; com idade m&#233;dia de nove meses&#46; A CMB pareceu superestimar a desnutri&#231;&#227;o&#44; pois 71&#44;1&#37; dos pacientes apresentaram algum grau de deple&#231;&#227;o&#44; com 83&#44;3&#37; entre o grupo de pacientes com cirrose e 66&#44;7&#37; entre o grupo de pacientes sem cirrose&#46; A avalia&#231;&#227;o da CMB feita apenas em pacientes com mais de um ano pode explicar esses resultados&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">No que diz respeito &#224; ingest&#227;o alimentar&#44; 57&#44;2&#37; de 91 pacientes ingeriram menos de 95&#37; da recomenda&#231;&#227;o nutricional&#44; sem diferen&#231;as significativas entre pacientes com e sem cirrose &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;32&#41; e entre crian&#231;as com e sem icter&#237;cia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;80&#41;&#59; esse achado pode estar relacionado ao fato de que a avalia&#231;&#227;o nutricional foi feita em um &#250;nico momento&#46; Ao comparar os pacientes com baixa ingest&#227;o de calorias com aqueles com algum grau de deple&#231;&#227;o nutricional identificado por meio da CB&#44; da TST ou da CMB&#44; n&#227;o houve diferen&#231;a estat&#237;stica&#46; Esses m&#233;todos provaram ser semelhantes e importantes na avalia&#231;&#227;o nutricional de pacientes com colestase cr&#244;nica&#46; Da mesma forma&#44; Cardoso et al&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> mostraram &#237;ndices ainda mais elevados de dietas inadequadas &#40;90&#37;&#41; quando a ingest&#227;o de alimentos foi avaliada quantitativa e qualitativamente&#46; Isso &#233; ainda mais preocupante&#44; uma vez que a ingest&#227;o cal&#243;rica deve ser aprimorada at&#233; 140&#37; do esperado&#46; Considerando essa recomenda&#231;&#227;o&#44; apenas 2&#44;2&#37; dos pacientes apresentaram uma ingest&#227;o cal&#243;rica adequada&#46; Ap&#243;s essa avalia&#231;&#227;o&#44; as fam&#237;lias foram orientadas a respeito da ingest&#227;o de alimentos e das necessidades diet&#233;ticas&#44; por&#233;m os resultados das interven&#231;&#245;es ainda n&#227;o foram estudados&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">Estamos cientes das limita&#231;&#245;es de nosso estudo&#46; A mais importante delas &#233; que a avalia&#231;&#227;o nutricional foi feita em um &#250;nico momento&#44; o que dificulta as compara&#231;&#245;es entre pacientes com ou sem cirrose e com ou sem icter&#237;cia&#44; pois os pacientes est&#227;o em diferentes est&#225;gios da doen&#231;a&#46; Outra limita&#231;&#227;o estava relacionada ao di&#225;rio alimentar&#44; pois&#44; mesmo se formos muito rigorosos na coleta de dados&#44; esse di&#225;rio sempre pode ter falhas&#44; j&#225; que depende da mem&#243;ria e da coopera&#231;&#227;o do paciente&#46; Al&#233;m disso&#44; uma quest&#227;o importante &#233; que a avalia&#231;&#227;o nutricional foi feita pelo mesmo nutricionista&#44; o ideal seria que fosse feita por dois nutricionistas com uma compara&#231;&#227;o posterior dos resultados&#46; Contudo&#44; acreditamos que essas limita&#231;&#245;es n&#227;o reduzem a import&#226;ncia de nossos achados&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">Concluindo&#44; o uso do peso na avalia&#231;&#227;o nutricional pode subestimar a detec&#231;&#227;o de desnutri&#231;&#227;o em pacientes com doen&#231;as hep&#225;ticas cr&#244;nicas devido a visceromegalia&#44; edema subcl&#237;nico e&#47;ou ascite&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> Os &#237;ndices que consideram peso e altura&#44; como P&#47;A e IMC&#44; tamb&#233;m podem n&#227;o mostrar o grau real de deple&#231;&#227;o atribu&#237;vel &#224; doen&#231;a cl&#237;nica cr&#244;nica desses pacientes em que tanto o peso quanto a altura s&#227;o prejudicados&#46; As medidas de TST e CB parecem par&#226;metros mais precisos de avalia&#231;&#227;o nutricional de pacientes com doen&#231;as hep&#225;ticas e colestase&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conflitos de interesse</span><p id="par0165" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
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            0 => "Neonatal cholestasis"
            1 => "Nutrition"
            2 => "Chronic liver disease"
            3 => "Anthropometry"
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            0 => "Colestase neonatal"
            1 => "Nutri&#231;&#227;o"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To evaluate the nutritional status of children with persistent cholestasis and to compare the anthropometric indices between children with and without liver cirrhosis and children with and without jaundice&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Children with persistent cholestasis&#44; <span class="elsevierStyleItalic">i&#46;e</span> increased direct bilirrubin or changes in the canalicular enzyme gamma&#8208;glutamyl transferase &#40;GGT&#41;&#44; were included&#46; The anthropometric measures were weight &#40;W&#41;&#44; height or length &#40;H&#41;&#44; arm circumference &#40;AC&#41;&#44; triceps skinfold thickness &#40;TST&#41;&#44; arm muscle circumference &#40;AMC&#41;&#44; and body mass index &#40;BMI&#41;&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Ninety&#8208;one children with cholestasis&#44; with current median age of 12 months&#44; were evaluated&#46; W&#47;age &#40;A&#41; and H&#47;A indices below &#8211;2 Z&#8208;scores were observed in 33&#37; and 30&#46;8&#37; of patients&#44; respectively&#46; Concerning the W&#47;H index and BMI&#44; only 12&#37; and 16&#37; of patients&#44; respectively&#44; were below &#8211;2 Z&#8208;scores&#46; Regarding AC&#44; 43&#46;8&#37; of 89 evaluated patients had some depletion&#46; Observing the TST&#44; 64&#37; of patients had depletion&#44; and 71&#46;1&#37; of the 45 evaluated patients had some degree of depletion regarding the ACM index&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Evaluation using weight in patients with chronic liver diseases may overestimate the nutritional status due to visceromegaly&#44; subclinical edema&#44; or ascites&#46; Indices that correlate weight and height&#44; such as W&#47;H and BMI&#44; may also not show depletion because of the chronic condition in which there are depletion of both weight and height&#46; TST&#44; AC&#44; and ACM are parameters that better estimate nutritional status and should be part of the management of patients with liver diseases and cholestasis&#46;</p></span>"
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      "pt" => array:3 [
        "titulo" => "Resumo"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Avaliar a situa&#231;&#227;o nutricional de crian&#231;as com colestase persistente e comparar os &#237;ndices antropom&#233;tricos entre crian&#231;as com e sem cirrose hep&#225;tica e crian&#231;as com e sem icter&#237;cia&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Foram inclu&#237;das crian&#231;as com colestase persistente&#44; ou seja&#44; aumento da bilirrubina direta ou altera&#231;&#245;es na enzima canalicular&#44; gamaglutamiltransferase &#40;GGT&#41;&#46; As medidas antropom&#233;tricas foram peso&#44; estatura ou altura&#44; circunfer&#234;ncia do bra&#231;o &#40;CB&#41;&#44; espessura da prega cut&#226;nea do tr&#237;ceps &#40;TST&#41;&#44; circunfer&#234;ncia muscular do bra&#231;o &#40;CMB&#41; e &#237;ndice de massa corporal &#40;IMC&#41;&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Foram avaliadas 91 crian&#231;as com colestase&#44; com idade m&#233;dia de 12 meses&#59; 33&#37; e 30&#44;8&#37; dos pacientes apresentaram &#237;ndices P&#47;I e A&#47;I com escore Z abaixo de &#8211;2&#44; respectivamente&#46; Com rela&#231;&#227;o ao &#237;ndice P&#47;A e IMC&#44; somente 12&#37; e 16&#37; dos pacientes&#44; respectivamente&#44; apresentaram escore Z abaixo de &#8211;2&#46; Com rela&#231;&#227;o &#224; CB&#44; 43&#44;8&#37; de 89 pacientes avaliados apresentaram alguma deple&#231;&#227;o&#46; Observando a TST&#44; 64&#37; dos pacientes que apresentaram deple&#231;&#227;o&#44; 71&#44;1&#37; dos 45 pacientes avaliados apresentaram algum grau de deple&#231;&#227;o com rela&#231;&#227;o ao &#237;ndice de CMB&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#227;o</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A avalia&#231;&#227;o do peso em pacientes com doen&#231;as hep&#225;ticas cr&#244;nicas poder&#225; superestimar a situa&#231;&#227;o nutricional devido a visceromegalia&#44; edema subcl&#237;nico ou ascite&#46; Os &#237;ndices que correlacionam peso e altura&#44; como P&#47;A e IMC&#44; tamb&#233;m podem n&#227;o mostrar deple&#231;&#227;o devido &#224; doen&#231;a cr&#244;nica em que h&#225; deple&#231;&#227;o tanto do peso quanto da altura&#46; A TST&#44; BC e CMB s&#227;o par&#226;metros que estimam melhor a situa&#231;&#227;o nutricional e devem fazer parte de gest&#227;o de pacientes com doen&#231;as hep&#225;ticas e colestase&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Objetivo"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "M&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclus&#227;o"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0035">Como citar este artigo&#58; Silva FV&#44; Ferri PM&#44; Queiroz TC&#44; Barbosa PS&#44; Oliveira MC&#44; Pereira LJ&#44; et al&#46; Nutritional evaluation of children with chronic cholestatic disease&#46; J Pediatr &#40;Rio J&#41;&#46; 2016&#59;92&#58;197&#8211;205&#46;</p>"
      ]
    ]
    "multimedia" => array:4 [
      0 => array:7 [
        "identificador" => "tbl0005"
        "etiqueta" => "Tabela 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">P&#47;I&#44; &#237;ndice peso&#47;idade&#59; A&#47;I&#44; &#237;ndice altura&#47;idade&#59; P&#47;A&#44; &#237;ndice peso&#47;altura&#59; IMC&#44; &#237;ndice de massa corporal&#59; TST&#44; espessura da prega cut&#226;nea do tr&#237;ceps&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col">Com cirrose&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#40;91 crian&#231;as&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">24 &#40;96&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">37 &#40;56&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21 &#40;84&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21 &#40;31&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hepatomegalia n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
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              "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Com rela&#231;&#227;o a alguns dados&#44; foram usados a mediana e o intervalo interquartil &#40;IQ 25&#176;&#8208;75&#176;&#41;&#59; com rela&#231;&#227;o ao di&#225;rio alimentar&#44; o c&#225;lculo usado foi&#58; registro do di&#225;rio alimentar&#47;recomendado para a idade x 100&#46;</p>"
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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Dados cl&#237;nicos&#44; laboratoriais&#44; nutricionais e antropom&#233;tricos de crian&#231;as diagnosticadas com colestase neonatal em geral e divididas de acordo com a presen&#231;a de cirrose</p>"
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          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">P&#47;I&#44; &#237;ndice peso&#47;idade&#59; A&#47;I&#44; &#237;ndice altura&#47;idade&#59; P&#47;A&#44; &#237;ndice peso&#47;altura&#59; IMC&#44; &#237;ndice de massa corporal&#59; TST&#44; espessura da prega cut&#226;nea do tr&#237;ceps&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
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                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Idade &#40;meses&#41;</span><a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">31 &#91;10&#8208;56&#44;5&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Cirrose</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">51 &#40;72&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10 &#40;47&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Esplenomegalia n &#40;5&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">37 &#40;52&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">05 &#40;23&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hepatomegalia n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48 &#40;68&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">09 &#40;42&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hepatoesplenomegalia n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">38 &#40;41&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17 &#40;24&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19 &#40;90&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Ascite n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 &#40;10&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Bilirrubina total &#40;md&#47;dL&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;4 &#91;1&#44;7&#8208;7&#44;45&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;5 &#91;0&#44;25&#8208;0&#44;7&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Bilirrubina direta &#40;mg&#47;dL&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#44;0 &#91;1&#44;37&#8208;5&#44;6&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;2 &#91;0&#44;1&#8208;0&#44;32&#93;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">402 &#91;180&#8208;686&#44;8&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">234 &#91;180&#8208;554&#93;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;1 &#91;3&#44;7&#8208;4&#44;45&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;2 &#91;4&#44;0&#8208;4&#44;6&#93;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Escore Z A&#47;I</span><a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">39 &#40;55&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;52&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>95&#37; a 105&#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;15&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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              "nota" => "<p class="elsevierStyleNotepara" id="npar0010">Com rela&#231;&#227;o a alguns dados&#44; foram usados a mediana e o intervalo interquartil &#40;IQ 25&#176;&#8208;75&#176;&#41;&#59; com rela&#231;&#227;o ao di&#225;rio alimentar&#44; o c&#225;lculo usado foi registro do di&#225;rio alimentar&#47;recomendado para a idade x 100&#46;</p>"
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          "pt" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Dados cl&#237;nicos&#44; laboratoriais&#44; nutricionais e antropom&#233;tricos de crian&#231;as diagnosticadas com colestase neonatal em geral e divididas de acordo com a presen&#231;a de icter&#237;cia</p>"
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          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Obs&#46;&#58; Para a avalia&#231;&#227;o do &#237;ndice A&#47;I&#44; o escore Z foi classificado como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2&#41;&#46; Para a avalia&#231;&#227;o do &#237;ndice P&#47;I&#44; como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;2&#41;&#59; Alto &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;2&#41;&#46; Para a avalia&#231;&#227;o do &#237;ndice P&#47;A&#44; como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;1&#41;&#59; Alto &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;1&#41;&#46; Para a avalia&#231;&#227;o do IMC&#44; o escore Z foi classificado como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;1&#41;&#59; Risco de sobrepeso &#40;&#62; escore Z &#43;1 e &#8804; escore Z &#43;2&#41; e &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;2 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#43;3&#41;&#46; Para a avalia&#231;&#227;o da Circunfer&#234;ncia do Bra&#231;o&#44; da Espessura da Prega Cut&#226;nea do Tr&#237;ceps e da Circunfer&#234;ncia Muscular do Bra&#231;o&#44; a classifica&#231;&#227;o utilizada foi&#58; Deple&#231;&#227;o grave&#58; 70&#37; do esperado&#59; Deple&#231;&#227;o moderada&#58; &#8805; 70&#37; e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>80&#37; do esperado&#59; Deple&#231;&#227;o leve&#58; &#8805; 80&#37; e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>90&#37; do esperado&#59; Eutrofia&#58; &#8805; 90&#37; e &#8804; 110&#37; do esperado&#59; Sobrepeso<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>110&#37; e &#8804; 120&#37; do esperado&#59; e Obesidade&#58;<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>120&#37; do esperado&#46;</p>"
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              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#205;ndice&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Geral &#40;91 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Com cirrose &#40;25 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Sem cirrose &#40;66 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Altura&#47;Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;17&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;16&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;13&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;12&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;13&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63 &#40;69&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;68&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46 &#40;69&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Peso&#47;Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;16&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19 &#40;20&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;21&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59 &#40;64&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;60&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">44 &#40;66&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Alto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;2&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;1&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Peso&#47;Altura</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;6&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;6&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;5&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;12&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;15&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">66 &#40;72&#44;50&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;64&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">50 &#40;75&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Alto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;15&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;25&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;15&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">&#205;ndice de massa corporal</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;7&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;12&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;6&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;8&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;16&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;6&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59 &#40;64&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;48&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">44 &#40;66&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Risco de sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;17&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;21&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;1&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Circunfer&#234;ncia do bra&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">a</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;3&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;3&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;7&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;3&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;32&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;44&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18 &#40;28&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42 &#40;47&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;28&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35 &#40;54&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;8&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Obesidade&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Espessura da prega cut&#226;nea do tr&#237;ceps</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21 &#40;23&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;48&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;13&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;16&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;8&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;19&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;6&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;8&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;6&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;18&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;16&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;19&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;15&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Obesidade&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21 &#40;23&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;16&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;25&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Circunfer&#234;ncia muscular do bra&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">b</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;13&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;16&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;22&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;33&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;18&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;35&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;33&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;36&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;28&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;16&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;33&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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              "identificador" => "tblfn0015"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0015">O n&#250;mero total de pacientes avaliados neste &#237;ndice foi 89&#46;</p>"
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            1 => array:3 [
              "identificador" => "tblfn0020"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0020">O n&#250;mero total de pacientes avaliados neste &#237;ndice foi 45&#46;</p>"
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          "pt" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Classifica&#231;&#227;o nutricional com base nos &#237;ndices antropom&#233;tricos de todo o grupo de pacientes e estratificado de acordo com a presen&#231;a de cirrose</p>"
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          "leyenda" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Obs&#46;&#58; Para a avalia&#231;&#227;o do &#237;ndice A&#47;I&#44; o escore Z foi classificado como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2&#41;&#46; Para a avalia&#231;&#227;o do &#237;ndice P&#47;I&#44; como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e &#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;2&#41;&#59; Alto &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;2&#41;&#46; Para a avalia&#231;&#227;o do &#237;ndice P&#47;A&#44; como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;1&#41;&#59; Alto &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;1&#41;&#46; Para a avalia&#231;&#227;o do IMC&#44; o escore Z foi classificado como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;1&#41;&#59; Risco de sobrepeso &#40;&#62; escore Z &#43;1 e &#8804; escore Z &#43;2&#41; e &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;2 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#43;3&#41;&#46; Para a avalia&#231;&#227;o da Circunfer&#234;ncia do Bra&#231;o&#44; da Espessura da Prega Cut&#226;nea do Tr&#237;ceps e da Circunfer&#234;ncia Muscular do Bra&#231;o&#44; a classifica&#231;&#227;o usada foi&#58; Deple&#231;&#227;o grave&#58; 70&#37; do esperado&#59; Deple&#231;&#227;o moderada&#58; &#8805; 70&#37; e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>80&#37; do esperado&#59; Deple&#231;&#227;o leve&#58; &#8805; 80&#37; e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>90&#37; do esperado&#59; Eutrofia&#58; &#8805; 90&#37; e &#8804; 110&#37; do esperado&#59; Sobrepeso<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>110&#37; e &#8804; 120&#37; do esperado&#59; e Obesidade&#58;<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>120&#37; do esperado&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#205;ndice&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Geral &#40;91 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Com icter&#237;cia &#40;70 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Sem icter&#237;cia &#40;21 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Altura&#47;Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;17&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;13&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;15&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63 &#40;69&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">45 &#40;64&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18 &#40;85&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Peso&#47;Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;12&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19 &#40;20&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;24&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59 &#40;64&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42 &#40;60&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;81&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Peso&#47;Altura</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Alto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;2&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;2&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;6&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;5&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">66 &#40;72&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">53 &#40;75&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;61&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Alto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;15&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;33&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">IMC</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;7&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;8&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;8&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;11&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59 &#40;64&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48 &#40;68&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;52&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Risco de sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;17&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;42&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;1&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;1&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Circunfer&#234;ncia do bra&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0025"><span class="elsevierStyleSup">a</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;3&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;4&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;7&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;32&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24 &#40;35&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;23&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42 &#40;47&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;42&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;61&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;8&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;14&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Obesidade&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Espessura da prega cut&#226;nea do tr&#237;ceps</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21 &#40;23&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19 &#40;27&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;16&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;21&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;6&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;18&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;11&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;42&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;11&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;14&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Obesidade&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21 &#40;23&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;21&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;28&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Circunfer&#234;ncia muscular do bra&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0030"><span class="elsevierStyleSup">b</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;13&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;22&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;26&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;35&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;40&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;26&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;28&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;46&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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                0 => "xTab1031771.png"
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            ]
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          "notaPie" => array:2 [
            0 => array:3 [
              "identificador" => "tblfn0025"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0025">O n&#250;mero total de pacientes avaliados neste &#237;ndice foi 89&#46;</p>"
            ]
            1 => array:3 [
              "identificador" => "tblfn0030"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0030">O n&#250;mero total de pacientes avaliados neste &#237;ndice foi 45&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "pt" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Classifica&#231;&#227;o nutricional com base nos &#237;ndices antropom&#233;tricos de todo o grupo de pacientes e estratificada de acordo com a presen&#231;a de icter&#237;cia</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Refer&#234;ncias"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:25 [
            0 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "EASL Clinical Practice Guidelines&#58; management of cholestatic liver diseases"
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Artigo original
Nutritional evaluation of children with chronic cholestatic disease
Avaliação nutricional de crianças com colestase crônica
Francislaine Veiga da Silvaa,b, Priscila Menezes Ferrib,c,
Autor para correspondência
pmferri.liu@gmail.com

Autor para correspondência.
, Thaís Costa Nascentes Queirozb,d, Pamela de Souza Haueisen Barbosae, Maria Cristina Cassiano de Oliveiraf, Laura Jácome de Melo Pereirad, Ana Cristina Simões e Silvac,g, Francisco José Pennab,c, Eleonora Druve Tavares Fagundesb,c, Alexandre Rodrigues Ferreirab,c,
Autor para correspondência
alexfer1403@gmail.com

Autor para correspondência.
a Grupo de Hepatologia e Gastroenterologia Pediátrica, Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil
b Grupo de Gastroenterologia Pediátrica, Faculdade de Medicina, Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil
c Departamento de Pediatria, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil
d Gastroenterologista Pediátrico, Brasil
e Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil
f Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil
g Laboratório Interdisciplinar de Investigação Médica, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil
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          0 => array:3 [
            "entidad" => "Grupo de Hepatologia e Gastroenterologia Pedi&#225;trica&#44; Hospital das Cl&#237;nicas&#44; Universidade Federal de Minas Gerais &#40;UFMG&#41;&#44; Belo Horizonte&#44; MG&#44; Brasil"
            "etiqueta" => "a"
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          ]
          1 => array:3 [
            "entidad" => "Grupo de Gastroenterologia Pedi&#225;trica&#44; Faculdade de Medicina&#44; Hospital das Cl&#237;nicas&#44; Universidade Federal de Minas Gerais &#40;UFMG&#41;&#44; Belo Horizonte&#44; MG&#44; Brasil"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Departamento de Pediatria&#44; Faculdade de Medicina&#44; Universidade Federal de Minas Gerais &#40;UFMG&#41;&#44; Belo Horizonte&#44; MG&#44; Brasil"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Gastroenterologista Pedi&#225;trico&#44; Brasil"
            "etiqueta" => "d"
            "identificador" => "aff0020"
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          4 => array:3 [
            "entidad" => "Faculdade de Medicina&#44; Universidade Federal de Minas Gerais &#40;UFMG&#41;&#44; Belo Horizonte&#44; MG&#44; Brasil"
            "etiqueta" => "e"
            "identificador" => "aff0025"
          ]
          5 => array:3 [
            "entidad" => "Hospital das Cl&#237;nicas&#44; Universidade Federal de Minas Gerais &#40;UFMG&#41;&#44; Belo Horizonte&#44; MG&#44; Brasil"
            "etiqueta" => "f"
            "identificador" => "aff0030"
          ]
          6 => array:3 [
            "entidad" => "Laborat&#243;rio Interdisciplinar de Investiga&#231;&#227;o M&#233;dica&#44; Universidade Federal de Minas Gerais &#40;UFMG&#41;&#44; Belo Horizonte&#44; MG&#44; Brasil"
            "etiqueta" => "g"
            "identificador" => "aff0035"
          ]
        ]
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          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Autor para correspond&#234;ncia&#46;"
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    "titulosAlternativos" => array:1 [
      "pt" => array:1 [
        "titulo" => "Avalia&#231;&#227;o nutricional de crian&#231;as com colestase cr&#244;nica"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introdu&#231;&#227;o</span><p id="par0005" class="elsevierStylePara elsevierViewall">Colestase &#233; uma manifesta&#231;&#227;o comum de doen&#231;a hep&#225;tica em crian&#231;as&#44; que ocorre em cerca de 65&#37; desses pacientes&#46; A doen&#231;a consiste no impedimento do fluxo da bile devido a uma obstru&#231;&#227;o no trato biliar ou um impedimento da absor&#231;&#227;o&#44; conjuga&#231;&#227;o ou excre&#231;&#227;o de &#225;cidos biliares&#46;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">1&#44;2</span></a> A colestase prejudica a situa&#231;&#227;o nutricional dessas crian&#231;as&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">3</span></a> A desnutri&#231;&#227;o leva &#224; morbidez e mortalidade cada vez maiores em pacientes com doen&#231;a hep&#225;tica cr&#244;nica&#46; Barshes et al&#46;<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">4</span></a> relataram que a desnutri&#231;&#227;o no per&#237;odo anterior ao transplante est&#225; associada a maior interna&#231;&#227;o e gastos hospitalares&#46; Al&#233;m disso&#44; Moukarzel et al&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">5</span></a> mostraram uma estreita correla&#231;&#227;o entre situa&#231;&#227;o nutricional e resultados do transplante de f&#237;gado em crian&#231;as&#46; Neste estudo&#44; crian&#231;as com um escore Z abaixo de &#8211;2 desvios padr&#227;o apresentaram uma incid&#234;ncia mais elevada de infec&#231;&#227;o no per&#237;odo posterior ao transplante&#44; mais complica&#231;&#245;es cir&#250;rgicas e mortalidade mais elevada&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Aproximadamente 60&#37; das crian&#231;as com doen&#231;a hep&#225;tica cr&#244;nica est&#227;o abaixo do peso e da altura esperados para sua idade&#46;<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">6&#44;7</span></a> Uma assist&#234;ncia nutricional adequada pode evitar a r&#225;pida progress&#227;o da doen&#231;a de base&#44; com melhoria da fun&#231;&#227;o imune&#46;<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">6&#44;8&#44;9</span></a> A avalia&#231;&#227;o nutricional dessas crian&#231;as &#233; essencial&#44; por&#233;m o peso pode ser superestimado em casos de visceromegalia&#44; ascite e edema perif&#233;rico&#59; portanto&#44; separadamente&#44; essa avalia&#231;&#227;o n&#227;o &#233; um bom par&#226;metro para identificar a desnutri&#231;&#227;o&#46; As medidas mais sens&#237;veis para determinar a situa&#231;&#227;o nutricional na doen&#231;a hep&#225;tica cr&#244;nica s&#227;o a circunfer&#234;ncia do bra&#231;o e a prega cut&#226;nea do tr&#237;ceps&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">10</span></a> Um exame f&#237;sico meticuloso&#44; v&#225;rias medidas f&#237;sicas e antropom&#233;tricas e exames complementares individualizados s&#227;o indispens&#225;veis&#46; Como a desnutri&#231;&#227;o &#233; consequ&#234;ncia da colestase cr&#244;nica&#44; o conhecimento do impacto dessa doen&#231;a em crian&#231;as afetadas poder&#225; auxiliar na recomenda&#231;&#227;o de uma interven&#231;&#227;o nutricional&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">O objetivo deste estudo &#233; avaliar a situa&#231;&#227;o nutricional de crian&#231;as diagnosticadas com colestase acompanhadas na Cl&#237;nica de Hepatologia Pedi&#225;trica de nossa institui&#231;&#227;o e correlacionar a ingest&#227;o de alimentos com a situa&#231;&#227;o nutricional&#46; Al&#233;m disso&#44; os &#237;ndices antropom&#233;tricos s&#227;o comparados em pacientes com e sem cirrose hep&#225;tica e crian&#231;as com e sem icter&#237;cia&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Pacientes e m&#233;todos</span><p id="par0020" class="elsevierStylePara elsevierViewall">Este estudo de s&#233;rie de casos foi feito na Cl&#237;nica de Hepatologia Pedi&#225;trica de nossa institui&#231;&#227;o &#40;Hospital das Cl&#237;nicas&#44; UFMG&#44; Brasil&#41; de janeiro de 2009 a dezembro de 2013&#46; Foram inclu&#237;das crian&#231;as com colestase cl&#237;nica e&#47;ou laboratorial persistente&#46; A colestase persistente foi definida como um aumento da bilirrubina direta &#40;bilirrubina direta acima de 20&#37; da bilirrubina total ou acima de 2<span class="elsevierStyleHsp" style=""></span>mg&#47;dL quando os n&#237;veis est&#227;o acima de 5<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#44; ou bilirrubina direta acima de 1<span class="elsevierStyleHsp" style=""></span>mg&#47;dL quando o total &#233; inferior a 5<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41; ou aumento da enzima canalicular&#44; gamaglutamiltransferase &#40;GGT&#41;&#44; acima do valor de refer&#234;ncia para a idade&#46;<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">11</span></a> Todos os pacientes foram submetidos a bi&#243;psia do f&#237;gado&#44; indicada na avalia&#231;&#227;o inicial do paciente para obter um diagn&#243;stico diferenciado da colestase e&#47;ou durante o curso da doen&#231;a para o monitoramento de achados histopatol&#243;gicos&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">O estudo foi aprovado pelo Comit&#234; de &#201;tica de nossa institui&#231;&#227;o &#40;n&#250;mero de protocolo ETIC 310&#47;08&#41;&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">As medidas antropom&#233;tricas foram peso&#44; estatura ou altura&#44; circunfer&#234;ncia do bra&#231;o &#40;CB&#41;&#44; espessura da prega cut&#226;nea do tr&#237;ceps &#40;TST&#41;&#44; circunfer&#234;ncia muscular do bra&#231;o &#40;CMB&#41; e &#237;ndice de massa corporal &#40;IMC&#41;&#46; As vari&#225;veis analisadas foram&#58; sexo&#44; idade em meses na &#233;poca da avalia&#231;&#227;o cl&#237;nica&#44; classifica&#231;&#227;o em com e sem cirrose &#40;com base na histopatologia&#41;&#44; classifica&#231;&#227;o da cirrose pelos crit&#233;rios de Child&#8208;Pugh&#44; testes de laborat&#243;rio &#40;albumina e bilirrubina&#41; e ingest&#227;o cal&#243;rica por meio do di&#225;rio alimentar de 72 horas&#46; Os dados cl&#237;nicos e laboratoriais foram obtidos na mesma &#233;poca da avalia&#231;&#227;o nutricional&#44; ou seja&#44; em um &#250;nico momento&#46; A ingest&#227;o de alimentos foi registrada durante 72 horas ap&#243;s a avalia&#231;&#227;o nutricional&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">As crian&#231;as com menos de dois anos e com peso at&#233; 16<span class="elsevierStyleHsp" style=""></span>kg foram medidas por um antrop&#244;metro horizontal &#40;R&#233;gua Antropom&#233;trica Pedi&#225;trica&#44; NutriVida<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; Brasil&#41; e pesadas&#44; sem roupas e fralda&#44; em uma balan&#231;a eletr&#244;nica digital calibrada &#40;Balan&#231;a Digital Infantil&#44; Welmy<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; Brasil&#41;&#46; O estadi&#244;metro vertical &#40;Physical NutriVida<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; Brasil&#41; e uma plataforma eletr&#244;nica digital calibrada &#40;Balan&#231;a Digital&#44; Balmak<span class="elsevierStyleSup">&#174;</span>&#44; S&#227;o Paulo&#44; Brasil&#41; foram usados para medir crian&#231;as com mais de dois anos&#46; Os pacientes foram avaliados descal&#231;os e&#44; normalmente&#44; apenas com roupas &#237;ntimas&#46; Todos os equipamentos foram verificados antes de ser usados&#46; Essas medidas foram classificadas com o aux&#237;lio do protocolo Sisvan &#40;Sistema de Vigil&#226;ncia Alimentar e Nutricional&#41; 2008<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">12</span></a> por fase da vida&#44; adaptado da Organiza&#231;&#227;o Mundial de Sa&#250;de 2006&#59;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">13</span></a> os pontos de corte usados tiveram os gr&#225;ficos da OMS como refer&#234;ncia e foram calculados pela vers&#227;o 3&#46;2&#46;2 do Anthro da OMS&#46;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">14</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Uma fita inel&#225;stica foi usada para medir a CBe um plic&#244;metro para a medi&#231;&#227;o do TST&#46; Esses par&#226;metros foram calculados e classificados com base nos padr&#245;es da OMS de acordo com idade e altura&#46;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">15</span></a> As medidas foram feitas no lado direito da crian&#231;a&#46; Os pacientes com menos de dois anos foram avaliados de p&#233;&#44; no colo da m&#227;e ou do tutor&#46; A CB foi medida em um ponto intermedi&#225;rio entre o acr&#244;mio e a borda inferior do olecrano&#46; A TST foi medida na mesma posi&#231;&#227;o da CB&#44; ou seja&#44; no lado posterior do bra&#231;o&#46; A medi&#231;&#227;o foi feita ao longo do eixo longitudinal do membro&#46; Tr&#234;s medidas foram tiradas na mesma posi&#231;&#227;o com uma diferen&#231;a de tr&#234;s segundos entre si e a m&#233;dia dos valores foi calculada para evitar poss&#237;veis erros conforme recomendado pela literatura&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">12</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Os pacientes foram classificados com base no c&#225;lculo do <span class="elsevierStyleItalic">software</span> Anthro<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">14</span></a> da OMS ao usar os seguintes valores&#58; deple&#231;&#227;o grave &#40;menos de 70&#37;&#41;&#44; deple&#231;&#227;o moderada &#40;entre 70&#37; e 80&#37;&#41;&#44; deple&#231;&#227;o leve &#40;entre 80&#37; e 90&#37;&#41;&#44; eutrofia &#40;entre 90&#37; e 110&#37;&#41;&#44; sobrepeso &#40;entre 110&#37; e 120&#37;&#41; e obesidade &#40;mais de 120&#37;&#41;&#46; As f&#243;rmulas para esses c&#225;lculos foram&#58; adequa&#231;&#227;o da CB &#40;&#37;&#41;<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#91;CB obtida &#40;cm&#41; &#247; 50&#176; percentil da CB&#93; x 100&#59; adequa&#231;&#227;o da TST &#40;&#37;&#41;<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#91;TST obtida &#40;cm&#41; &#247; 50&#176; percentil da TST&#93; x 100&#59; CMB &#40;cm&#41;<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>CB &#40;cm&#41; &#8208; 3&#44;14 x TST &#40;cm&#41;&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Os valores de CMB&#44; de acordo com sexo e idade&#44; foram comparados com os valores de refer&#234;ncia do Levantamento Nacional de Exame de Sa&#250;de e Nutri&#231;&#227;o &#40;NHANES&#41;&#44; expressos em tabelas de percentis por Frisancho a partir de um ano de idade&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">16</span></a> Pacientes com menos de um ano foram exclu&#237;dos desta an&#225;lise devido &#224; aus&#234;ncia de valores de refer&#234;ncia para essa faixa et&#225;ria&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Ap&#243;s uma avalia&#231;&#227;o cl&#237;nica&#44; o cuidador da crian&#231;a relatou todos os alimentos ingeridos pela crian&#231;a por tr&#234;s dias consecutivos&#46; Foram informados o n&#250;mero de dias&#44; o hor&#225;rio&#44; o tipo e a quantidade de comida ingerida pela crian&#231;a&#46; Quanto a crian&#231;as exclusivamente amamentadas&#44; a m&#227;e anotou o hor&#225;rio da amamenta&#231;&#227;o para estimar&#44; de acordo com a idade e o tempo de suc&#231;&#227;o&#44; o volume de leite ingerido pelo neonato&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">O c&#225;lculo da ingest&#227;o de calorias e prote&#237;nas foi feito com o <span class="elsevierStyleItalic">software</span> DietPro&#44; vers&#227;o 4&#46;0 &#40;Agrom&#237;dia Softwares<span class="elsevierStyleSup">&#174;</span>&#44; Minas Gerais&#44; Brasil&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">17</span></a> bem como com base na Tabela de Composi&#231;&#227;o de Alimentos de S&#244;nia Tucunduva<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">18</span></a> e na tabela de medidas caseiras&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">19</span></a> incluindo os macronutrientes carboidrato&#44; prote&#237;na e lip&#237;dio&#46; A seguir&#44; as recomenda&#231;&#245;es di&#225;rias de calorias foram calculadas de acordo com a idade pela Organiza&#231;&#227;o das Na&#231;&#245;es Unidas para Agricultura e Alimenta&#231;&#227;o &#40;FAO&#47;OMS&#47;ONU&#41; 1985&#44; com base na necessidade cal&#243;rica de consumo total de energia mais o crescimento de crian&#231;as amamentadas&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">20</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">Os dados foram analisados pelo Epi Info&#44; vers&#227;o 6&#46;04 &#40;Centro de Controle e Preven&#231;&#227;o de Doen&#231;as&#44; Atlanta&#44; EUA&#41;&#46; As vari&#225;veis cont&#237;nuas com distribui&#231;&#227;o n&#227;o gaussiana foram apresentadas como medianas e intervalo interquartil &#40;IQ do 25&#176; ao 75&#176;&#41; e comparadas com o teste de Kruskal&#8208;Wallis n&#227;o param&#233;trico&#46; A distribui&#231;&#227;o das vari&#225;veis dicot&#244;micas foi comparada pelo teste qui&#8208;quadrado&#44; com corre&#231;&#227;o de Yates&#44; ou pelo teste exato de Fisher bicaudal&#44; caso necess&#225;rio&#46; A probabilidade foi considerada significativa quando inferior a 0&#44;05 &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41;&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="par0070" class="elsevierStylePara elsevierViewall">Foram avaliadas 91 crian&#231;as com diagn&#243;stico inicial de colestase&#46; A idade m&#233;dia era de 12 meses e 52&#44;7&#37; delas eram do sexo masculino&#46; As etiologias de colestase eram&#58; atresia biliar em 31 pacientes &#40;34&#44;1&#37;&#41;&#44; hepatite neonatal idiop&#225;tica em 25 &#40;27&#44;5&#37;&#41;&#44; colestase multifatorial em oito &#40;8&#44;8&#37;&#41;&#44; s&#237;ndrome de Alagille em oito &#40;8&#44;8&#37;&#41;&#44; defici&#234;ncia de alfa&#8208;1&#8208;antitripsina em seis &#40;6&#44;6&#37;&#41;&#44; hipoplasia de vias biliares em quatro &#40;4&#44;4&#37;&#41; e outros diagn&#243;sticos em seis &#40;6&#44;6&#37;&#41;&#59; 25 pacientes &#40;27&#44;5&#37;&#41; apresentaram cirrose no exame histopatol&#243;gico &#40;18 com atresia biliar e sete com hepatite neonatal idiop&#225;tica&#41; e 11 pacientes foram classificados como Child&#8208;Pug A &#40;44&#37;&#41;&#44; 12 como B &#40;48&#37;&#41; e dois como C &#40;8&#37;&#41;&#59; 70 &#40;76&#44;9&#37;&#41; apresentaram icter&#237;cia com n&#237;veis excepcionalmente altos de bilirrubina&#44; GGT e aminotransferase&#44; ao passo que 21 crian&#231;as &#40;23&#44;1&#37;&#41; apresentaram n&#237;veis normais de bilirrubina&#44; sem icter&#237;cia&#44; por&#233;m com aumento dos n&#237;veis de GGT&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Dados cl&#237;nicos&#44; laboratoriais&#44; nutricionais e antropom&#233;tricos dos pacientes s&#227;o apresentados nas <a class="elsevierStyleCrossRefs" href="#tbl0005">tabelas 1 e 2</a>&#46; As seguintes abreviaturas foram usadas&#58; P&#47;I&#58; &#237;ndice peso&#47;idade&#59; A&#47;I&#58; &#237;ndice altura&#47;idade&#59; P&#47;A&#58; &#237;ndice peso&#47;altura&#59; IMC&#58; &#237;ndice de massa corporal&#46; Com rela&#231;&#227;o a alguns dados&#44; marcados com um asterisco&#44; foram usadas a mediana e o intervalo interquartil &#40;IQ 25&#176;&#8208;75&#176;&#41;&#59; com rela&#231;&#227;o ao di&#225;rio alimentar&#44; o c&#225;lculo usado foi registro do di&#225;rio alimentar&#47;recomendado para a idade x 100&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0080" class="elsevierStylePara elsevierViewall">No que diz respeito &#224; ingest&#227;o nutricional&#44; 57&#44;2&#37; dos 91 pacientes estavam 95&#37; abaixo das calorias recomendadas&#44; sem diferen&#231;a estatisticamente significativa entre os com e sem cirrose &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;32&#41; e entre crian&#231;as com e sem icter&#237;cia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;80&#41;&#46; Ao comparar pacientes com ingest&#227;o 95&#37; abaixo do recomendado com os pacientes com deple&#231;&#227;o nutricional&#44; n&#227;o encontramos diferen&#231;a estatisticamente significativa na CB &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;14&#41;&#44; na TST &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;09&#41; e na CMB &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;09&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">A <a class="elsevierStyleCrossRef" href="#tbl0015">tabela 3</a> mostra a classifica&#231;&#227;o nutricional com base em &#237;ndices antropom&#233;tricos em todo o grupo e em pacientes estratificados de acordo com a presen&#231;a de cirrose&#46; N&#227;o houve diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose com rela&#231;&#227;o aos &#237;ndices P&#47;I &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;48&#41; e A&#47;I &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;92&#41;&#44; bem como n&#227;o houve diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose com rela&#231;&#227;o aos &#237;ndices P&#47;A &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;28&#41; e IMC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;07&#41;&#46; Com rela&#231;&#227;o &#224; CB&#44; houve uma diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;006&#41;&#46; Com rela&#231;&#227;o &#224; TST e &#224; CMB&#44; n&#227;o houve uma diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;07 para TST e 83&#44;3&#37; em compara&#231;&#227;o a 66&#44;7&#37; com p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;24 para CMB&#41;&#46; A <a class="elsevierStyleCrossRef" href="#tbl0020">tabela 4</a> apresenta a classifica&#231;&#227;o nutricional com base em &#237;ndices antropom&#233;tricos em todo o grupo e em pacientes estratificados de acordo com a presen&#231;a de icter&#237;cia&#46; Nenhuma diferen&#231;a foi observada na compara&#231;&#227;o entre os dados de crian&#231;as com e sem icter&#237;cia com rela&#231;&#227;o ao &#237;ndice P&#47;I &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;18&#41;&#44; A&#47;I &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;92&#41;&#44; P&#47;A &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;45&#41; e IMC &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;07&#41;&#46; No que diz respeito &#224; presen&#231;a de qualquer grau de deple&#231;&#227;o na CB e na TST&#44; pacientes com icter&#237;cia apresentaram frequ&#234;ncia significativamente maior de deple&#231;&#227;o em ambos os par&#226;metros do que os sem icter&#237;cia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;045 e p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#44; respectivamente&#41;&#46; N&#227;o houve diferen&#231;a estatisticamente significativa com rela&#231;&#227;o &#224; CMB &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;08&#41;&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0090" class="elsevierStylePara elsevierViewall">Ao comparar pacientes com deple&#231;&#227;o nutricional por TST com pacientes com baixo peso para a altura ou idade&#44; encontramos uma diferen&#231;a estatisticamente significativa em ambos &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;000&#41;&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">No que diz respeito &#224; avalia&#231;&#227;o da CB&#44; 39 &#40;43&#44;8&#37;&#41; de 89 pacientes apresentaram algum grau de deple&#231;&#227;o&#46; Por outro lado&#44; ao avaliar e comparar com o P&#47;A&#44; observamos que apenas 11 &#40;12&#44;3&#37;&#41; de 89 pacientes apresentaram baixo peso para a altura &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; e com o P&#47;I&#44; apenas 28 &#40;31&#44;5&#37;&#41; apresentaram baixo peso para a idade &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;000&#41;&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">Da mesma forma&#44; quando avaliamos a CMB&#44; 32 &#40;71&#44;1&#37;&#41; de 45 pacientes apresentaram algum grau de deple&#231;&#227;o&#44; ao passo que apenas dois &#40;4&#44;4&#37;&#41; apresentaram baixo peso para a altura &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;000&#41; e apenas sete &#40;15&#44;6&#37;&#41; de 45 pacientes apresentaram baixo peso para a idade &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;000&#41;&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discuss&#227;o</span><p id="par0105" class="elsevierStylePara elsevierViewall">A avalia&#231;&#227;o nutricional dessas crian&#231;as &#233; essencial&#44; por&#233;m apresenta diversos desafios&#46; A presen&#231;a de visceromegalia&#44; ascite e edema perif&#233;rico pode limitar o uso do peso&#44; o &#237;ndice mais comum de avalia&#231;&#227;o nutricional&#46; Portanto&#44; um exame f&#237;sico meticuloso&#44; v&#225;rias medidas antropom&#233;tricas e exames complementares individualizados s&#227;o essenciais para uma avalia&#231;&#227;o nutricional confi&#225;vel desses pacientes&#46; As medidas de TST e CB s&#227;o mais confi&#225;veis porque esses par&#226;metros n&#227;o levam em considera&#231;&#227;o o peso e podem ser extremamente importantes na pr&#225;tica cl&#237;nica ao permitir um diagn&#243;stico antecipado de d&#233;ficits nutricionais&#46; A estimativa de dep&#243;sitos de gordura por meio da TST e de conte&#250;do proteico pela CMB e CB s&#227;o dados complementares que permitem a avalia&#231;&#227;o nutricional precisa desses pacientes&#46;<a class="elsevierStyleCrossRefs" href="#bib0140"><span class="elsevierStyleSup">3&#44;21&#44;22</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">Neste estudo&#44; um ter&#231;o dos pacientes mostrou &#237;ndices P&#47;A e A&#47;I com escore Z abaixo de &#8211;2&#46; Considerando o &#237;ndice P&#47;A&#44; apenas 12&#44;1&#37; dos pacientes apresentaram escore Z abaixo de &#8211;2&#59; com rela&#231;&#227;o ao IMC&#44; o percentual foi de 16&#44;5&#37;&#46; Isso mostra que o &#237;ndice P&#47;A sempre deve ser usado em combina&#231;&#227;o com o &#237;ndice A&#47;I&#44; j&#225; que os d&#233;ficits proporcionais no peso e altura n&#227;o s&#227;o identificados nesse primeiro m&#233;todo&#44; e mostra tamb&#233;m que o IMC n&#227;o permite uma boa aferi&#231;&#227;o da composi&#231;&#227;o corporal&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Da mesma forma&#44; em outro estudo brasileiro com 22 crian&#231;as e adolescentes com colestase&#44; 23&#44;8&#37; e 33&#44;3&#37; dos pacientes estavam malnutridos de acordo com os crit&#233;rios de P&#47;I e A&#47;I&#44; respectivamente&#44; e nenhum deles ficou com escore Z abaixo de &#8211;2 com rela&#231;&#227;o ao &#237;ndice P&#47;A&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">23</span></a> A inadequa&#231;&#227;o nutricional foi maior quando os &#237;ndices de CB&#44; TST e CMB foram usados&#46; A CB revelou 43&#44;9&#37; dos pacientes com algum grau de deple&#231;&#227;o&#44; a TST mostrou 46&#44;2&#37; e a CMB&#44; 71&#44;1&#37;&#46; Embora os &#237;ndices P&#47;I e a A&#47;I tenham revelado quase um ter&#231;o de pacientes com deple&#231;&#227;o nutricional&#44; os &#237;ndices CB&#44; TST e CMB mostraram maior frequ&#234;ncia de desnutri&#231;&#227;o&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">A CMB provavelmente mostrou uma propor&#231;&#227;o maior de pacientes com nutri&#231;&#227;o inadequada em compara&#231;&#227;o com a CB e a TST devido &#224; idade dos pacientes avaliados neste estudo&#46; A CMB foi relatada apenas em pacientes acima de um ano&#44; ou seja&#44; com um tempo mais longo de evolu&#231;&#227;o da colestase&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Schneider et al&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">24</span></a> relataram em seu estudo sobre crian&#231;as com cirrose que o &#237;ndice que refletiu melhor o risco nutricional foi a TST&#46; Isso confirma que ela pode medir a massa de gordura corporal e mostrar a extens&#227;o e a gravidade da desnutri&#231;&#227;o&#46; Portanto&#44; essa medida &#233; muito importante na avalia&#231;&#227;o nutricional desses pacientes&#46; Sokol et al&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">25</span></a> enfatizaram a import&#226;ncia das medidas de TST e CB como m&#233;todos mais precisos de avaliar dep&#243;sitos de gordura e teor de prote&#237;na em pacientes com doen&#231;a hep&#225;tica cr&#244;nica&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Com rela&#231;&#227;o aos &#237;ndices de P&#47;I e IMC&#44; ocorre uma falha importante&#44; que pode ser explicada&#44; pelo menos em parte&#44; pelo padr&#227;o cr&#244;nico de comprometimento nutricional observado nesses pacientes quando tanto o peso quanto a altura est&#227;o envolvidos&#46; Isso refor&#231;a que o uso de &#237;ndices antropom&#233;tricos convencionais como P&#47;I&#44; A&#47;I&#44; P&#47;A e IMC pode superestimar a situa&#231;&#227;o nutricional de pacientes com colestase&#44; mesmo quando edema e ascite n&#227;o s&#227;o evidentes&#46; Al&#233;m disso&#44; a visceromegalia contribui para o aumento do peso desses pacientes&#44; o que compromete o uso de &#237;ndices que incluem peso&#46;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">2</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">A inadequa&#231;&#227;o desses &#237;ndices tamb&#233;m pode ser observada ao se compararem pacientes com e sem icter&#237;cia e com e sem cirrose hep&#225;tica&#46; Nenhuma diferen&#231;a estat&#237;stica foi detectada entre esses subgrupos com rela&#231;&#227;o aos &#237;ndices P&#47;I&#44; A&#47;I&#44; P&#47;A ou IMC&#46; Por outro lado&#44; a avalia&#231;&#227;o da CB mostrou uma diferen&#231;a estatisticamente significativa entre pacientes com e sem cirrose e entre crian&#231;as com e sem icter&#237;cia&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">A avalia&#231;&#227;o da TST e da CMB n&#227;o apresentou diferen&#231;a estat&#237;stica entre pacientes com e sem cirrose&#46; Isso pode ser explicado pelo fato de que a avalia&#231;&#227;o dos pacientes foi feita em um &#250;nico momento&#46; Em resumo&#44; na maioria dos casos&#44; a desnutri&#231;&#227;o foi detectada apenas quando a avalia&#231;&#227;o n&#227;o estava restrita &#224;s medidas de peso e altura&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">A frequ&#234;ncia de deple&#231;&#227;o nutricional com base na avalia&#231;&#227;o da CB e da TST foi semelhante&#44; o que indica deple&#231;&#227;o semelhante de gordura e massa magra&#46; Esse achado diferiu dos resultados relatados por Cardoso et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> que observaram perda inicial de gordura mais elevada&#46; Essa diferen&#231;a pode ser atribu&#237;da &#224; idade dos pacientes&#44; pois&#44; no estudo de Cardoso et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> os pacientes eram mais novos&#44; com idade m&#233;dia de nove meses&#46; A CMB pareceu superestimar a desnutri&#231;&#227;o&#44; pois 71&#44;1&#37; dos pacientes apresentaram algum grau de deple&#231;&#227;o&#44; com 83&#44;3&#37; entre o grupo de pacientes com cirrose e 66&#44;7&#37; entre o grupo de pacientes sem cirrose&#46; A avalia&#231;&#227;o da CMB feita apenas em pacientes com mais de um ano pode explicar esses resultados&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">No que diz respeito &#224; ingest&#227;o alimentar&#44; 57&#44;2&#37; de 91 pacientes ingeriram menos de 95&#37; da recomenda&#231;&#227;o nutricional&#44; sem diferen&#231;as significativas entre pacientes com e sem cirrose &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;32&#41; e entre crian&#231;as com e sem icter&#237;cia &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;80&#41;&#59; esse achado pode estar relacionado ao fato de que a avalia&#231;&#227;o nutricional foi feita em um &#250;nico momento&#46; Ao comparar os pacientes com baixa ingest&#227;o de calorias com aqueles com algum grau de deple&#231;&#227;o nutricional identificado por meio da CB&#44; da TST ou da CMB&#44; n&#227;o houve diferen&#231;a estat&#237;stica&#46; Esses m&#233;todos provaram ser semelhantes e importantes na avalia&#231;&#227;o nutricional de pacientes com colestase cr&#244;nica&#46; Da mesma forma&#44; Cardoso et al&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> mostraram &#237;ndices ainda mais elevados de dietas inadequadas &#40;90&#37;&#41; quando a ingest&#227;o de alimentos foi avaliada quantitativa e qualitativamente&#46; Isso &#233; ainda mais preocupante&#44; uma vez que a ingest&#227;o cal&#243;rica deve ser aprimorada at&#233; 140&#37; do esperado&#46; Considerando essa recomenda&#231;&#227;o&#44; apenas 2&#44;2&#37; dos pacientes apresentaram uma ingest&#227;o cal&#243;rica adequada&#46; Ap&#243;s essa avalia&#231;&#227;o&#44; as fam&#237;lias foram orientadas a respeito da ingest&#227;o de alimentos e das necessidades diet&#233;ticas&#44; por&#233;m os resultados das interven&#231;&#245;es ainda n&#227;o foram estudados&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">Estamos cientes das limita&#231;&#245;es de nosso estudo&#46; A mais importante delas &#233; que a avalia&#231;&#227;o nutricional foi feita em um &#250;nico momento&#44; o que dificulta as compara&#231;&#245;es entre pacientes com ou sem cirrose e com ou sem icter&#237;cia&#44; pois os pacientes est&#227;o em diferentes est&#225;gios da doen&#231;a&#46; Outra limita&#231;&#227;o estava relacionada ao di&#225;rio alimentar&#44; pois&#44; mesmo se formos muito rigorosos na coleta de dados&#44; esse di&#225;rio sempre pode ter falhas&#44; j&#225; que depende da mem&#243;ria e da coopera&#231;&#227;o do paciente&#46; Al&#233;m disso&#44; uma quest&#227;o importante &#233; que a avalia&#231;&#227;o nutricional foi feita pelo mesmo nutricionista&#44; o ideal seria que fosse feita por dois nutricionistas com uma compara&#231;&#227;o posterior dos resultados&#46; Contudo&#44; acreditamos que essas limita&#231;&#245;es n&#227;o reduzem a import&#226;ncia de nossos achados&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">Concluindo&#44; o uso do peso na avalia&#231;&#227;o nutricional pode subestimar a detec&#231;&#227;o de desnutri&#231;&#227;o em pacientes com doen&#231;as hep&#225;ticas cr&#244;nicas devido a visceromegalia&#44; edema subcl&#237;nico e&#47;ou ascite&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">21</span></a> Os &#237;ndices que consideram peso e altura&#44; como P&#47;A e IMC&#44; tamb&#233;m podem n&#227;o mostrar o grau real de deple&#231;&#227;o atribu&#237;vel &#224; doen&#231;a cl&#237;nica cr&#244;nica desses pacientes em que tanto o peso quanto a altura s&#227;o prejudicados&#46; As medidas de TST e CB parecem par&#226;metros mais precisos de avalia&#231;&#227;o nutricional de pacientes com doen&#231;as hep&#225;ticas e colestase&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conflitos de interesse</span><p id="par0165" class="elsevierStylePara elsevierViewall">Os autores declaram n&#227;o haver conflitos de interesse&#46;</p></span></span>"
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            0 => "Neonatal cholestasis"
            1 => "Nutrition"
            2 => "Chronic liver disease"
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            0 => "Colestase neonatal"
            1 => "Nutri&#231;&#227;o"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To evaluate the nutritional status of children with persistent cholestasis and to compare the anthropometric indices between children with and without liver cirrhosis and children with and without jaundice&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Children with persistent cholestasis&#44; <span class="elsevierStyleItalic">i&#46;e</span> increased direct bilirrubin or changes in the canalicular enzyme gamma&#8208;glutamyl transferase &#40;GGT&#41;&#44; were included&#46; The anthropometric measures were weight &#40;W&#41;&#44; height or length &#40;H&#41;&#44; arm circumference &#40;AC&#41;&#44; triceps skinfold thickness &#40;TST&#41;&#44; arm muscle circumference &#40;AMC&#41;&#44; and body mass index &#40;BMI&#41;&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Ninety&#8208;one children with cholestasis&#44; with current median age of 12 months&#44; were evaluated&#46; W&#47;age &#40;A&#41; and H&#47;A indices below &#8211;2 Z&#8208;scores were observed in 33&#37; and 30&#46;8&#37; of patients&#44; respectively&#46; Concerning the W&#47;H index and BMI&#44; only 12&#37; and 16&#37; of patients&#44; respectively&#44; were below &#8211;2 Z&#8208;scores&#46; Regarding AC&#44; 43&#46;8&#37; of 89 evaluated patients had some depletion&#46; Observing the TST&#44; 64&#37; of patients had depletion&#44; and 71&#46;1&#37; of the 45 evaluated patients had some degree of depletion regarding the ACM index&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Evaluation using weight in patients with chronic liver diseases may overestimate the nutritional status due to visceromegaly&#44; subclinical edema&#44; or ascites&#46; Indices that correlate weight and height&#44; such as W&#47;H and BMI&#44; may also not show depletion because of the chronic condition in which there are depletion of both weight and height&#46; TST&#44; AC&#44; and ACM are parameters that better estimate nutritional status and should be part of the management of patients with liver diseases and cholestasis&#46;</p></span>"
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      "pt" => array:3 [
        "titulo" => "Resumo"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Avaliar a situa&#231;&#227;o nutricional de crian&#231;as com colestase persistente e comparar os &#237;ndices antropom&#233;tricos entre crian&#231;as com e sem cirrose hep&#225;tica e crian&#231;as com e sem icter&#237;cia&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Foram inclu&#237;das crian&#231;as com colestase persistente&#44; ou seja&#44; aumento da bilirrubina direta ou altera&#231;&#245;es na enzima canalicular&#44; gamaglutamiltransferase &#40;GGT&#41;&#46; As medidas antropom&#233;tricas foram peso&#44; estatura ou altura&#44; circunfer&#234;ncia do bra&#231;o &#40;CB&#41;&#44; espessura da prega cut&#226;nea do tr&#237;ceps &#40;TST&#41;&#44; circunfer&#234;ncia muscular do bra&#231;o &#40;CMB&#41; e &#237;ndice de massa corporal &#40;IMC&#41;&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Foram avaliadas 91 crian&#231;as com colestase&#44; com idade m&#233;dia de 12 meses&#59; 33&#37; e 30&#44;8&#37; dos pacientes apresentaram &#237;ndices P&#47;I e A&#47;I com escore Z abaixo de &#8211;2&#44; respectivamente&#46; Com rela&#231;&#227;o ao &#237;ndice P&#47;A e IMC&#44; somente 12&#37; e 16&#37; dos pacientes&#44; respectivamente&#44; apresentaram escore Z abaixo de &#8211;2&#46; Com rela&#231;&#227;o &#224; CB&#44; 43&#44;8&#37; de 89 pacientes avaliados apresentaram alguma deple&#231;&#227;o&#46; Observando a TST&#44; 64&#37; dos pacientes que apresentaram deple&#231;&#227;o&#44; 71&#44;1&#37; dos 45 pacientes avaliados apresentaram algum grau de deple&#231;&#227;o com rela&#231;&#227;o ao &#237;ndice de CMB&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclus&#227;o</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A avalia&#231;&#227;o do peso em pacientes com doen&#231;as hep&#225;ticas cr&#244;nicas poder&#225; superestimar a situa&#231;&#227;o nutricional devido a visceromegalia&#44; edema subcl&#237;nico ou ascite&#46; Os &#237;ndices que correlacionam peso e altura&#44; como P&#47;A e IMC&#44; tamb&#233;m podem n&#227;o mostrar deple&#231;&#227;o devido &#224; doen&#231;a cr&#244;nica em que h&#225; deple&#231;&#227;o tanto do peso quanto da altura&#46; A TST&#44; BC e CMB s&#227;o par&#226;metros que estimam melhor a situa&#231;&#227;o nutricional e devem fazer parte de gest&#227;o de pacientes com doen&#231;as hep&#225;ticas e colestase&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Objetivo"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "M&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclus&#227;o"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0035">Como citar este artigo&#58; Silva FV&#44; Ferri PM&#44; Queiroz TC&#44; Barbosa PS&#44; Oliveira MC&#44; Pereira LJ&#44; et al&#46; Nutritional evaluation of children with chronic cholestatic disease&#46; J Pediatr &#40;Rio J&#41;&#46; 2016&#59;92&#58;197&#8211;205&#46;</p>"
      ]
    ]
    "multimedia" => array:4 [
      0 => array:7 [
        "identificador" => "tbl0005"
        "etiqueta" => "Tabela 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">P&#47;I&#44; &#237;ndice peso&#47;idade&#59; A&#47;I&#44; &#237;ndice altura&#47;idade&#59; P&#47;A&#44; &#237;ndice peso&#47;altura&#59; IMC&#44; &#237;ndice de massa corporal&#59; TST&#44; espessura da prega cut&#226;nea do tr&#237;ceps&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col">Com cirrose&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#40;91 crian&#231;as&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">24 &#40;96&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">37 &#40;56&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21 &#40;84&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">21 &#40;31&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hepatomegalia n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
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              "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Com rela&#231;&#227;o a alguns dados&#44; foram usados a mediana e o intervalo interquartil &#40;IQ 25&#176;&#8208;75&#176;&#41;&#59; com rela&#231;&#227;o ao di&#225;rio alimentar&#44; o c&#225;lculo usado foi&#58; registro do di&#225;rio alimentar&#47;recomendado para a idade x 100&#46;</p>"
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          "pt" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Dados cl&#237;nicos&#44; laboratoriais&#44; nutricionais e antropom&#233;tricos de crian&#231;as diagnosticadas com colestase neonatal em geral e divididas de acordo com a presen&#231;a de cirrose</p>"
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          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">P&#47;I&#44; &#237;ndice peso&#47;idade&#59; A&#47;I&#44; &#237;ndice altura&#47;idade&#59; P&#47;A&#44; &#237;ndice peso&#47;altura&#59; IMC&#44; &#237;ndice de massa corporal&#59; TST&#44; espessura da prega cut&#226;nea do tr&#237;ceps&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
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                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Idade &#40;meses&#41;</span><a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">31 &#91;10&#8208;56&#44;5&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Cirrose</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">51 &#40;72&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10 &#40;47&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Esplenomegalia n &#40;5&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">37 &#40;52&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">05 &#40;23&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hepatomegalia n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">48 &#40;68&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">09 &#40;42&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hepatoesplenomegalia n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">38 &#40;41&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17 &#40;24&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">19 &#40;90&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Ascite n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 &#40;10&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Bilirrubina total &#40;md&#47;dL&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3&#44;4 &#91;1&#44;7&#8208;7&#44;45&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;5 &#91;0&#44;25&#8208;0&#44;7&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Bilirrubina direta &#40;mg&#47;dL&#41;</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#44;0 &#91;1&#44;37&#8208;5&#44;6&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;2 &#91;0&#44;1&#8208;0&#44;32&#93;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">402 &#91;180&#8208;686&#44;8&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">234 &#91;180&#8208;554&#93;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;1 &#91;3&#44;7&#8208;4&#44;45&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;2 &#91;4&#44;0&#8208;4&#44;6&#93;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Escore Z A&#47;I</span><a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">39 &#40;55&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;52&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>95&#37; a 105&#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;15&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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              "nota" => "<p class="elsevierStyleNotepara" id="npar0010">Com rela&#231;&#227;o a alguns dados&#44; foram usados a mediana e o intervalo interquartil &#40;IQ 25&#176;&#8208;75&#176;&#41;&#59; com rela&#231;&#227;o ao di&#225;rio alimentar&#44; o c&#225;lculo usado foi registro do di&#225;rio alimentar&#47;recomendado para a idade x 100&#46;</p>"
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          "pt" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Dados cl&#237;nicos&#44; laboratoriais&#44; nutricionais e antropom&#233;tricos de crian&#231;as diagnosticadas com colestase neonatal em geral e divididas de acordo com a presen&#231;a de icter&#237;cia</p>"
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          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Obs&#46;&#58; Para a avalia&#231;&#227;o do &#237;ndice A&#47;I&#44; o escore Z foi classificado como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2&#41;&#46; Para a avalia&#231;&#227;o do &#237;ndice P&#47;I&#44; como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;2&#41;&#59; Alto &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;2&#41;&#46; Para a avalia&#231;&#227;o do &#237;ndice P&#47;A&#44; como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;1&#41;&#59; Alto &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;1&#41;&#46; Para a avalia&#231;&#227;o do IMC&#44; o escore Z foi classificado como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;1&#41;&#59; Risco de sobrepeso &#40;&#62; escore Z &#43;1 e &#8804; escore Z &#43;2&#41; e &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;2 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#43;3&#41;&#46; Para a avalia&#231;&#227;o da Circunfer&#234;ncia do Bra&#231;o&#44; da Espessura da Prega Cut&#226;nea do Tr&#237;ceps e da Circunfer&#234;ncia Muscular do Bra&#231;o&#44; a classifica&#231;&#227;o utilizada foi&#58; Deple&#231;&#227;o grave&#58; 70&#37; do esperado&#59; Deple&#231;&#227;o moderada&#58; &#8805; 70&#37; e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>80&#37; do esperado&#59; Deple&#231;&#227;o leve&#58; &#8805; 80&#37; e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>90&#37; do esperado&#59; Eutrofia&#58; &#8805; 90&#37; e &#8804; 110&#37; do esperado&#59; Sobrepeso<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>110&#37; e &#8804; 120&#37; do esperado&#59; e Obesidade&#58;<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>120&#37; do esperado&#46;</p>"
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              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#205;ndice&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Geral &#40;91 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Com cirrose &#40;25 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Sem cirrose &#40;66 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Altura&#47;Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;17&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;16&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;13&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;12&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;13&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63 &#40;69&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;68&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46 &#40;69&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Peso&#47;Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;16&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19 &#40;20&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;21&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59 &#40;64&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;60&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">44 &#40;66&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Alto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;2&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;1&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Peso&#47;Altura</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;6&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;6&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;5&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;12&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;15&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">66 &#40;72&#44;50&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;64&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">50 &#40;75&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Alto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;15&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;25&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;15&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">&#205;ndice de massa corporal</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;7&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;12&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;6&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;8&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;16&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;6&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59 &#40;64&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;48&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">44 &#40;66&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Risco de sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;17&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;21&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;1&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Circunfer&#234;ncia do bra&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">a</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;3&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;3&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;7&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;3&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;32&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;44&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18 &#40;28&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42 &#40;47&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;28&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35 &#40;54&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;8&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Obesidade&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Espessura da prega cut&#226;nea do tr&#237;ceps</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21 &#40;23&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;48&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;13&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;16&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;8&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;19&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;6&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;8&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;6&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;18&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;16&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;19&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;15&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Obesidade&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21 &#40;23&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;16&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;25&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Circunfer&#234;ncia muscular do bra&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">b</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;13&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;16&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;22&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;33&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;18&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;35&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;33&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;36&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;28&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;16&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;33&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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              "identificador" => "tblfn0015"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0015">O n&#250;mero total de pacientes avaliados neste &#237;ndice foi 89&#46;</p>"
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            1 => array:3 [
              "identificador" => "tblfn0020"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0020">O n&#250;mero total de pacientes avaliados neste &#237;ndice foi 45&#46;</p>"
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          "pt" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Classifica&#231;&#227;o nutricional com base nos &#237;ndices antropom&#233;tricos de todo o grupo de pacientes e estratificado de acordo com a presen&#231;a de cirrose</p>"
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          "leyenda" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Obs&#46;&#58; Para a avalia&#231;&#227;o do &#237;ndice A&#47;I&#44; o escore Z foi classificado como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2&#41;&#46; Para a avalia&#231;&#227;o do &#237;ndice P&#47;I&#44; como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e &#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;2&#41;&#59; Alto &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;2&#41;&#46; Para a avalia&#231;&#227;o do &#237;ndice P&#47;A&#44; como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;1&#41;&#59; Alto &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;1&#41;&#46; Para a avalia&#231;&#227;o do IMC&#44; o escore Z foi classificado como Muito Baixo &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;3&#41;&#59; Baixo &#40;escore Z &#8805; &#8211;3 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#8211;2&#41;&#59; Adequado &#40;escore Z &#8805; &#8211;2 e &#8804; &#43;1&#41;&#59; Risco de sobrepeso &#40;&#62; escore Z &#43;1 e &#8804; escore Z &#43;2&#41; e &#40;escore Z<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#43;2 e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#43;3&#41;&#46; Para a avalia&#231;&#227;o da Circunfer&#234;ncia do Bra&#231;o&#44; da Espessura da Prega Cut&#226;nea do Tr&#237;ceps e da Circunfer&#234;ncia Muscular do Bra&#231;o&#44; a classifica&#231;&#227;o usada foi&#58; Deple&#231;&#227;o grave&#58; 70&#37; do esperado&#59; Deple&#231;&#227;o moderada&#58; &#8805; 70&#37; e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>80&#37; do esperado&#59; Deple&#231;&#227;o leve&#58; &#8805; 80&#37; e<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>90&#37; do esperado&#59; Eutrofia&#58; &#8805; 90&#37; e &#8804; 110&#37; do esperado&#59; Sobrepeso<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>110&#37; e &#8804; 120&#37; do esperado&#59; e Obesidade&#58;<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>120&#37; do esperado&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#205;ndice&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Geral &#40;91 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Com icter&#237;cia &#40;70 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Sem icter&#237;cia &#40;21 pacientes&#41;&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Altura&#47;Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;17&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;13&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;15&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63 &#40;69&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">45 &#40;64&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18 &#40;85&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Peso&#47;Idade</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;12&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19 &#40;20&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;24&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59 &#40;64&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42 &#40;60&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;81&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Peso&#47;Altura</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Alto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;2&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;2&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;6&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;5&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">66 &#40;72&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">53 &#40;75&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;61&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Alto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;15&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;33&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">IMC</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Muito baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;7&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;8&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Baixo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;8&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;11&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Adequado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59 &#40;64&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48 &#40;68&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;52&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Risco de sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;17&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;42&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;1&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;1&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Circunfer&#234;ncia do bra&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0025"><span class="elsevierStyleSup">a</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;3&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;4&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;7&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;10&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;32&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24 &#40;35&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;23&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42 &#40;47&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;42&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;61&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;8&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;14&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Obesidade&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#44;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Espessura da prega cut&#226;nea do tr&#237;ceps</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21 &#40;23&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19 &#40;27&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;16&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;21&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;6&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;4&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;18&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;11&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;42&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Sobrepeso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;12&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;11&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;14&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Obesidade&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21 &#40;23&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;21&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;28&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="char" valign="top"><span class="elsevierStyleItalic">Circunfer&#234;ncia muscular do bra&#231;o</span><a class="elsevierStyleCrossRef" href="#tblfn0030"><span class="elsevierStyleSup">b</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o grave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;13&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;22&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;26&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Deple&#231;&#227;o leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;35&#44;6&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;40&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;26&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Eutrofia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;28&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;20&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;46&#44;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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                0 => "xTab1031771.png"
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            ]
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          "notaPie" => array:2 [
            0 => array:3 [
              "identificador" => "tblfn0025"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0025">O n&#250;mero total de pacientes avaliados neste &#237;ndice foi 89&#46;</p>"
            ]
            1 => array:3 [
              "identificador" => "tblfn0030"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0030">O n&#250;mero total de pacientes avaliados neste &#237;ndice foi 45&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "pt" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Classifica&#231;&#227;o nutricional com base nos &#237;ndices antropom&#233;tricos de todo o grupo de pacientes e estratificada de acordo com a presen&#231;a de icter&#237;cia</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Refer&#234;ncias"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:25 [
            0 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "EASL Clinical Practice Guidelines&#58; management of cholestatic liver diseases"
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ISSN: 22555536
Idioma original: Português
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