Short communicationVaricella vaccination coverage inverse correlation with varicella hospitalizations in Spain
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Conflict of interest statement
MSM is employee of Sanofi Pasteur, MSD, Spain. RGP and AGM have received support for grants and travel grants for Scientific Congress from Sanofi Pasteur, MSD and GSK.
Acknowledgement
The Subdirección General del Instituto de Información Sanitaria provided with the information in which this study is based.
References (20)
- et al.
A decline in varicella but an uncertain impact on zoster following varicella vaccination in Victoria, Australia
Vaccine
(2010) - et al.
Impact of universal vaccination on the epidemiology of varicella in Veneto, Italy
Vaccine
(2011) Varicella vaccination in Japan: necessity of implementing a routine vaccination program
J Infect Chemother
(2013)- et al.
Varicella rates among unvaccinated and one-dose vaccinated healthy children in Izmir, Turkey
Int J Infect Dis
(2011) - et al.
Modelling the impact of a combined varicella and zoster vaccination programme on the epidemiology of varicella zoster virus in England
Vaccine
(2011) - et al.
Evaluation of Australia's varicella vaccination program for children and adolescents
Vaccine
(2013) Systematic review of economic evaluation studies: are vaccination programs efficient in Spain?
Vaccine
(2013)- et al.
Varicella vaccination in Europe-taking the practical approach
BMC Med
(2009) - et al.
Varicella routine vaccination and the effects on varicella epidemiology—results from the Bavarian Varicella Surveillance Project (BaVariPro), 2006–2011
BMC Infect Dis
(2013) - et al.
Impact of vaccination on the epidemiology of varicella: 1995–2009
Pediatrics
(2014)
Cited by (16)
Impact of six years of routine varicella vaccination on the disease-related hospitalizations at Minas Gerais, Brazil
2022, VaccineCitation Excerpt :In this study, it was possible to ascertain that a 20% increase in vaccine coverage is able to reduce the number of varicella cases by up to 30% [25]. In Spain, an inverse relationship was established between the number of hospitalizations and the vaccine coverage rate [26]. The relevance of this relationship may help to clarify the peak in hospital admissions that occurred in 2017, when vaccination coverage rates lowered to under 80%.
Varicella vaccination as useful strategy for reducing the risk of varicella-related hospitalizations in both vaccinated and unvaccinated cohorts (Italy, 2003–2018)
2020, VaccineCitation Excerpt :These estimates were subjected to a significant reduction after the introduction of the varicella vaccination, with a decrease higher than 80% during the first five years. Similarly, decreasing percentages were found in other European countries, as Germany (−77.6% in children <5 years, VC = 53%) [22] or Spain (−83.5% in children <5 years, VC = 32%) [23] or in non-European countries such as Australia (−76.8% in children 1–4 years, VC = 90%) [24], Canada (−93.0% in children 1–4 years, VC = 93%) [25], and Uruguay (−94% in children 1–4 years, VC = 96%) [26]. We observed that hospitalization rates consistently decreased two or more years after the introduction of the vaccination and this finding would explain why some countries, with short observation period after vaccine implementation (2–4 years) and low vaccination coverage, could observe only smaller reductions.
Seeking the optimal schedule for chickenpox vaccination in Canada: Using an agent-based model to explore the impact of dose timing, coverage and waning of immunity on disease outcomes
2020, VaccineCitation Excerpt :Chickenpox vaccine timing is only one of a variety of other unknowns that may impact chickenpox disease outcomes. For instance, coverage rates vary by region, and it would be valuable to understand how this impacts herd immunity and population-level disease outcomes [9]. Moreover, there is substantial variation in the primary chickenpox vaccine failure estimates in the literature, as well as in estimates of the rate at which vaccine immunity wanes [10,11].
Evaluation of impact of one dose varicella vaccine on the incidence of chickenpox in Argentina
2020, VaccineCitation Excerpt :However, these studies are based on theoretical models, unlike this study, which incorporates varicella cases informed to the monitoring system [54]. It is expected that costs decrease as incidence rates and hospitalization decrease, as it occurs in other countries [55–57]. We would like to mention some limitations of the presented study.
Early impact of universal varicella vaccination on childhood varicella and herpes zoster hospitalizations in Brazil
2018, VaccineCitation Excerpt :The overall effectiveness of single dose varicella vaccine in preventing infection and severe disease is estimated to be 81 and 98%, respectively [6]. In a two doses schedule, the effectiveness against all forms of disease increases to more than 90%, with most of the data obtained from high-income countries, as United States of America, Australia, Germany, Italy, Spain and Canada [6–12]. In 2013, a tetraviral combined live and attenuated vaccine including measles, mumps, rubella and varicella (MMRV) was introduced in the Brazilian National Immunization Program (NIP), including all Brazilian states.