Original ArticleLactobacillus GG Improves Recovery in Infants with Blood in the Stools and Presumptive Allergic Colitis Compared with Extensively Hydrolyzed Formula Alone
Section snippets
Methods
Infants from 0 to 12 months of age, fed a casein-based routine formula or breast milk, with presumptive diagnosis of CMAC (see below) were enrolled in group A; group B (comparison group) included healthy infants of the same sex and age, matched for the type of feeding (formula or breast milk), recruited from the general population of a local pediatric practice. Exclusion criteria were as follows: infants with Hirschsprung's disease, any kind of malformation, history of intestinal
Results
Thirty infants in group A and 32 in group B were enrolled. Both groups were similar with respect to gestational age and anthropometric data at birth (not shown) and at the time of enrollment (Table I). Age ranged from 1 to 10 months. At enrollment, 26 infants in group A were being fed a casein-based formula, and 4 were exclusively breastfed. Eighteen infants in group B were fed a casein-based formula, and 14 were breastfed. As anthropometric data were not significantly different between formula
Discussion
In allergic enteritis/colitis the mucosal inflammatory process is most likely result of a reaction to dietary antigens, typically, cow's milk proteins.1, 2, 4, 17 The condition rapidly resolves after antigen exclusion, and a normal diet can usually be achieved by 1 year of age.18
Calprotectin is a calcium and zinc-binding protein that accounts for 60% of the cytosol proteins in neutrophils and is elevated in the presence of ongoing inflammation.19 There is an age-dependent variation in fecal
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Probiotics to Prebiotics and Their Clinical Use
2022, Encyclopedia of Infection and ImmunityThe Impact of Formula Choice for the Management of Pediatric Cow's Milk Allergy on the Occurrence of Other Allergic Manifestations: The Atopic March Cohort Study
2021, Journal of PediatricsCitation Excerpt :The results of this cohort study indicate that EHCF + LGG also has a greater potential in reducing disease duration. We provide additional evidence on the positive effect elicited by EHCF + LGG on immune tolerance acquisition in children with IgE-mediated CMA.18-23 In the present study, we confirmed that the effect of EHCF + LGG is sustained until 36 months of intervention also in comparison with other formulas.
Non-IgE-mediated food allergy
2023, Revista Alergia Mexico
Supported in part with funds from USDA/Agricultural Research Service under Cooperative Agreement number 58-6250-6001. The contents of this publication do not necessarily reflect the views or policies of the U.S. Department of Agriculture, nor does mention of trade names, commercial products, or organization imply endorsement by the U.S. Government. Mead Johnson Nutritionals supplied the blinded formula. The kits to analyze the stool samples for calprotectin were supplied by Eurospital. C.L. was a part-time employee of Mead Johnson Nutritionals while the study was planned and conducted. M.E.B. wrote the first draft of the manuscript, and no honorarium, grant, or other form of payment was given to anyone to produce the manuscript. The other authors declare no conflicts of interest.