ResearchResearch and Professional BriefTolerance of an Enteral Formula with Insoluble and Prebiotic Fiber in Children with Compromised Gastrointestinal Function
Section snippets
Methods
The study was conducted using a prospective, double-blind, randomized, 2×2 cross-over design during January 2005-June 2006.
Patients
A total of 14 participants were included in the study. All nine patients with neurological impairment had documented delayed gastric emptying by radionuclide scans and were fed exclusively through a gastrostomy tube. Both short bowel syndrome patients had intact colons and ileocecal valves, but about 12 inches of ileum resected during the neonatal period. They were fed orally and through a gastrostomy tube. The three patients with Crohn's disease had stable disease but poor weight gain and were
Conclusions
A 100% whey, peptide–based diet containing insoluble and prebiotic fiber was as well tolerated as a commercially available, fiber-free control diet in a small and heterogeneous population of children with impaired gastrointestinal function and was associated with a substantial improvement in stool consistency, especially in neurologically impaired children. Although participants had varied underlying diagnoses, they were all chronically tube-fed patients with well-established feeding regimens.
V. Khoshoo was consulting physician, Pediatric Gastroenterology and Nutrition, West Jefferson Medical Center, New Orleans, LA.
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Cited by (0)
V. Khoshoo was consulting physician, Pediatric Gastroenterology and Nutrition, West Jefferson Medical Center, New Orleans, LA.
S. S. Sun is professor and chair, Department of Biostatistics, and director, Biomedical Informatics, Virginia Commonwealth University, School of Medicine, Richmond, VA.
H. Storm is head of Clinical Sciences, Nestlé Nutrition, Florham Park, NJ.
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Deceased.