TY - JOUR T1 - Low FODMAPs diet for functional abdominal pain disorders in children: critical review of current knowledge JO - Jornal de Pediatria (English Edition) T2 - AU - Pensabene,Licia AU - Salvatore,Silvia AU - Turco,Rossella AU - Tarsitano,Flora AU - Concolino,Daniela AU - Baldassarre,Maria Elisabetta AU - Borrelli,Osvaldo AU - Thapar,Nikhil AU - Vandenplas,Yvan AU - Staiano,Annamaria AU - Saps,Miguel SN - 00217557 M3 - 10.1016/j.jped.2019.03.004 DO - 10.1016/j.jped.2019.03.004 UR - https://jped.elsevier.es/en-low-fodmaps-diet-for-functional-articulo-S002175571930110X AB - ObjectiveThis narrative review aimed to provide practitioners a synthesis of the current knowledge on the role of a low Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols diet in reducing symptoms associated with functional abdominal pain disorders in children. This review is focused on the pathophysiology, efficacy and criticism of low Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols diet in children. SourcesCochrane Database, Pubmed and Embase were searched using specific terms for Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols diet interventions and functional abdominal pain disorders. Summary of the findingsIn children, only one Randomized Control Trial and one open-label study reported positive results of low Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols diet; one Randomized Control Trial showed exacerbation of symptoms with fructans in children with Irritable Bowel Syndrome; no effect was found for the lactose-free diet whilst fructose-restricted diets were effective in 5/6 studies. ConclusionsIn children there are few trials evaluating low Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols in functional abdominal pain disorders, with encouraging data on the therapeutic efficacy particularly of fructose-restricted diet. Additional efforts are still needed to fill this research gap and clarify the most efficient way for tailoring dietary restrictions based on the patient's tolerance and/or identification of potential biomarkers of low Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols efficacy, to maintain nutritional adequacy and to simplify the adherence to diet by labeling Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols content in commercial products. ER -