TY - JOUR T1 - Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children JO - Jornal de Pediatria (English Edition) T2 - AU - Castro,Ana Paula Pereira AU - Hermsdorff,Helen Hermana Miranda AU - Milagres,Luana Cupertino AU - Albuquerque,Fernanda Martins de AU - Filgueiras,Mariana de Santis AU - Rocha,Naruna Pereira AU - Novaes,Juliana Farias de SN - 00217557 M3 - 10.1016/j.jped.2017.12.008 DO - 10.1016/j.jped.2017.12.008 UR - https://jped.elsevier.es/en-increased-apob-apoa1-ratio-is-associated-articulo-S0021755717306812 AB - ObjectiveTo investigate ApoB/ApoA1 ratio and its association with cardiovascular risk factors in children. MethodsCross-sectional study with 258 children aged 8 and 9 years old, enrolled in all urban schools in the city of Viçosa-MG. Anthropometric and body composition assessment, as well as biochemical profile of the children was performed. Socioeconomic variables and sedentary lifestyle were evaluated through a semi-structured questionnaire. ResultsMany children had excess weight (35.2%), abdominal adiposity (10.5%), and body fat (15.6%), as well as increased ApoB/ApoA1 ratio (14.7%), total cholesterol (51.8%), and triglycerides (19.8%). Children with excess weight and total and central fat had a higher prevalence of having a higher ApoB/ApoA1 ratio, as well as those with atherogenic lipid profile (increased LDL-c and triglycerides and low HDL-c). A direct association was found between the number of cardiovascular risk factors and the ApoB/ApoA1 ratio (p=0.001), regardless of age and income. ConclusionThe increased ApoB/ApoA1 ratio was associated with excess weight, body adiposity (total and central), and altered lipid profile in children. Children with a higher number of cardiovascular risk factors had higher ApoB/ApoA1 ratio, in both genders. ER -